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Results: 232
Encoding optical control in LCK kinase to quantitatively investigate its activity in live cells.
LCK is a tyrosine kinase that is essential for initiating T-cell antigen receptor (TCR) signaling. A complete understanding of LCK function is constrained by a paucity of methods to quantitatively study its function within live...
How Lean principles can be applied to the development process of educational programs?
Lean is an approach to improving business processes such as production. The overall objective of lean principles is to reduce waste and increase value. These principles have been developed and successfully applied within...
Published by: University of Salford
Acute rejection and growth outcomes in paediatric kidney allograft recipients treated with a corticosteroid minimisation immunosuppressive protocol.
BACKGROUND: Corticosteroid minimisation immunosuppressive protocols (CMP) for children are an approach to safely reduce unwanted medication side effects associated with long-term exposure following kidney transplantation. Here...
BK virus infection and outcome following kidney transplantation in childhood.
BK virus associated nephropathy (BKN) is an important cause of kidney allograft failure. In a cohort of paediatric kidney transplant recipients, we aimed to understand the incidence and clinical outcome associated with BKN, as...
Developing the menstrual justice agenda
This article develops the concept of ‘menstrual justice’. The legal scholar Margaret E. Johnson has developed an expansive approach to menstrual justice incorporating rights, justice and a framework for intersectional analysis...
Impact of Inflation and Credit Financing Policy on the Supply Chain With Learning
Technology drives many fields to improve the quality of items during the supply of the products. Despite proficient planning in the industrial system and the presence of sophisticated techniques, there may be some defective...
Published by: IGI Global Scientific Publishing
A General Approach for Financial Quantification of Climate Change Risk for Enterprises
Climate change is a major risk for the global economy. Increased frequency of climatic events coupled with unsustainable economic development without considering environmental & social aspects has resulted in runaway climatic...
Sustainable Development Business and Management Business and Organizational Research Media and Communications
Published by: IGI Global Scientific Publishing
A multisource energy harvesting utilizing highly efficient ferroelectric PMN-PT single crystal
This paper demonstrates a multi-source energy harvester that is able to utilize simultaneously both piezoelectric and pyroelectric effects in lead magnesium niobate-lead titanate (PMN-PT) single crystal. The paper presents a...
Developing the menstrual justice agenda
This article develops the concept of ‘menstrual justice’. The legal scholar Margaret E. Johnson has developed an expansive approach to menstrual justice incorporating rights, justice and a framework for intersectional analysis...
How Lean principles can be applied to the development process of educational programs?
Lean is an approach to improving business processes such as production. The overall objective of lean principles is to reduce waste and increase value. These principles have been developed and successfully applied within...
Published by: University of Salford
A multisource energy harvesting utilizing highly efficient ferroelectric PMN-PT single crystal
This paper demonstrates a multi-source energy harvester that is able to utilize simultaneously both piezoelectric and pyroelectric effects in lead magnesium niobate-lead titanate (PMN-PT) single crystal. The paper presents a...
BK virus infection and outcome following kidney transplantation in childhood
Abstract: BK virus associated nephropathy (BKN) is an important cause of kidney allograft failure. In a cohort of paediatric kidney transplant recipients, we aimed to understand the incidence and clinical outcome associated with...
Advanced glycation end products modulate amyloidogenic APP processing and Tau phosphorylation
Kedar Batkulwar, Rashmi Godbole, Reema Banarjee, Omar Kassaar, Robert J Williams, Mahesh Kulkarni
May 16, 2018
Advanced glycation end products (AGEs) are implicated in the pathology of Alzheimer's disease (AD), as they induce neurodegeneration following interaction with the receptor for AGE (RAGE). This study aimed to establish a...
Advanced glycation end products modulate amyloidogenic APP processing and Tau phosphorylation
Kedar Batkulwar, Rashmi Godbole, Reema Banarjee, Omar Kassaar, Robert J Williams, Mahesh Kulkarni
May 16, 2018
Advanced glycation end products (AGEs) are implicated in the pathology of Alzheimer's disease (AD), as they induce neurodegeneration following interaction with the receptor for AGE (RAGE). This study aimed to establish a...
Measurement of Student Engagement in a Generic and Online Learning Management System-Based Environment
Use of technology on campuses of higher education has changed how students are engaged in the process of learning. It also has brought lot of asynchrony to the definition of class room teaching, active learning, student-staff...
Published by: IGI Global Scientific Publishing
Clinical validation of a novel web-application for remote assessment of distance visual acuity.
Arun James Thirunavukarasu, Deborah Mullinger, Remi Mohan Rufus-Toye, Sarah Farrell, Louise E Allen
Oct 01, 2021
Background/objectives
Ophthalmic disorders cause 8% of hospital clinic attendances, the highest of any specialty. The fundamental need for a distance visual acuity (VA) measurement constrains remote consultation. A...
Impact of Credit Financing on the Ordering Policy for Imperfect Quality Items With Learning and Shortages
The paper develops an order quantity model with trade credit plus shortages under learning effects for deteriorating imperfect quality products. Generally, when the lot has imperfect items, the inspection of a lot is necessary...
Published by: IGI Global Scientific Publishing
Integrative analysis of copy number and gene expression in breast cancer using formalin-fixed paraffin-embedded core biopsy tissue
Mahesh Iddawela, Oscar Rueda, Jenny Eremin, Oleg Eremin, Jed Cowley, Helena Earl, Carlos Caldas
Jan 16, 2018
Humans Breast Neoplasms Formaldehyde Paraffin Embedding Tissue Fixation Feasibility Studies Gene Expression Profiling Gene Dosage Adult Aged Middle Aged Female
Published by: BMC genomics
Integrative analysis of copy number and gene expression in breast cancer using formalin-fixed paraffin-embedded core biopsy tissue
Mahesh Iddawela, Oscar Rueda, Jenny Eremin, Oleg Eremin, Jed Cowley, Helena M Earl, Carlos Caldas
Jul 12, 2017
BACKGROUND: An absence of reliable molecular markers has hampered individualised breast cancer treatments, and a major limitation for translational research is the lack of fresh tissue. There are, however, abundant banks of...
COVID-19 in People With Schizophrenia
As the global burden of mortality from COVID-19 continues to rise, an understanding of who is most at risk of adverse outcomes is of paramount importance. Pre-existing cardiometabolic, renal and respiratory diseases as well as...
Heard but not seen
We used capture (mist-netting) and acoustic methods to compare the species richness, abundance, and composition of a bat assemblage in different habitats in the Western Ghats of India. In the tropics, catching bats has been more...
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