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Results: 150
Evaluating the Clinical Feasibility of an Artificial Intelligence-Powered, Web-Based Clinical Decision Support System for the Treatment of Depression in Adults
Christina Popescu, Grace Golden, David Benrimoh, Myriam Tanguay-Sela, Dominique Slowey, Eryn Lundrigan, Jérôme Williams, Bennet Desormeau, Divyesh Kardani, Tamara Perez, Colleen Rollins, Sonia Israel, Kelly Perlman, Caitrin Armstrong, Jacob Baxter, Kate Whitmore, Marie-Jeanne Fradette, Kaelan Felcarek-Hope, Ghassen Soufi, Robert Fratila, Joseph Mehltretter, Karl Looper, Warren Steiner, Soham Rej, Jordan F Karp, Katherine Heller, Sagar V Parikh, Rebecca McGuire-Snieckus, Manuela Ferrari, Howard Margolese, Gustavo Turecki
Jan 06, 2022
BACKGROUND: Approximately two-thirds of patients with major depressive disorder do not achieve remission during their first treatment. There has been increasing interest in the use of digital, artificial intelligence-powered...
Dendritic cells induce antigen-specific regulatory T cells that prevent graft versus host disease and persist in mice
Foxp3 + regulatory T cells (T reg cells) effectively suppress immunity, but it is not determined if antigen-induced T reg cells (iT reg cells) are able to persist under conditions of inflammation and to stably express the...
regulatory T lymphocyte spleen cell dendritic cell graft versus host reaction mixed lymphocyte reaction
Published by: Rockefeller University
Dendritic cells induce a subpopulation of IL-12R?2-expressing treg that specifically consumes IL-12 to control Th1 responses
Cytokines secreted from dendritic cells (DCs) play an important role in the regulation of T helper (Th) cell differentiation and activation into effector cells. Therefore, controlling cytokine secretion from DCs may potentially...
interleukin 12 interleukin 6 Cell Proliferation Immunophenotyping Th1 cell dendritic cell Cytology regulatory T lymphocyte tumor necrosis factor
Published by: Rockefeller University
Customer Satisfaction Towards Online Shopping by Empirical Validation of Self-Determination Theory
The chapter aims at understanding the predictors of customer satisfaction with online shopping in India by using self-determination theory. This research validates perceived enjoyment, social influence, social media...
Published by: IGI Global Scientific Publishing
Spatio-Temporal Graph for Improvement of Decision-Making in Risks Treatment
Failures that hinder the proper functioning of complex systems are characterised by frequencies of occurrence, rates of evolution, and variables periodicities. Indeed, a good design of this kind of system requires the...
Published by: IGI Global Scientific Publishing
Motivations for Labour Provision on Digital Platforms in Europe
Research on the gig economy has rarely addressed the study on the motivations for the provision of labour services on digital platforms. Through a sample of 3,619 gigers in Europe, obtained from the COLLEM research, results have...
Published by: IGI Global Scientific Publishing
Digital future of luxury brands
Leading luxury brands have incorporated technologies to recreate brand images and reinvent consumer experience. The fashion industry is experiencing a historic transformation thanks to emerging technologies such as blockchain...
Flips, dualities and symmetry enhancements
Abstract: We present various 4d N = 1 theories enjoying IR global symmetry enhancement. The models we consider have the USp(2N) gauge group, 8 fundamental, one antisymmetric chirals and various numbers of gauge singlets. By...
Nuclear calcium signatures are associated with root development.
In plants, nuclear Ca2+ releases are essential to the establishment of nitrogen-fixing and phosphate-delivering arbuscular mycorrhizal endosymbioses. In the legume Medicago truncatula, these nuclear Ca2+ signals are generated by...
Digital future of luxury brands
Leading luxury brands have incorporated technologies to recreate brand images and reinvent consumer experience. The fashion industry is experiencing a historic transformation thanks to emerging technologies such as blockchain...
A Transmissible RNA Pathway in Honey Bees.
Eyal Maori, Yael Garbian, Vered Kunik, Rita Mozes-Koch, Osnat Malka, Haim Kalev, Niv Sabath, Ilan Sela, Sharoni Shafir
Apr 24, 2019
Brown and beige fat
Stefania Carobbio, Anne-Claire Guénantin, Isabella Samuelson, Myriam Bahri, Antonio Vidal-Puig
Nov 18, 2020
The adipose organ portrays adipocytes of diverse tones: white, brown and beige, each type with distinct functions. Adipocytes orchestrate their adaptation and expansion to provide storage to excess nutrients, the quick...
Accounting for the Multiple Natures of Missing Values in Label-Free Quantitative Proteomics Data Sets to Compare Imputation Strategies.
Targeting adhesion to the vascular niche to improve therapy for acute myeloid leukemia.
Niche hijack by malignant cells is considered to be a prominent cause of disease relapse. Barbier and colleagues uncover (E)-selectin as a novel mediator of malignant cell survival and regeneration which, upon blockade, has the...
Impact of tobacco outlet density and proximity on smoking cessation
A previous study conducted in the USA reported an association between residential proximity to a tobacco outlet and reduced likelihood of a quit attempt enduring beyond six months. We replicated this study in an English urban...
Genomic Analysis of Staphylococcus aureus of the Lineage CC130, Including mecC-Carrying MRSA and MSSA Isolates Recovered of Animal, Human, and Environmental Origins.
Paula Gómez, Laura Ruiz-Ripa, Rosa Fernández-Fernández, Haythem Gharsa, Karim Ben Slama, Ursula Höfle, Myriam Zarazaga, Mark A Holmes, Carmen Torres
Mar 04, 2021
Most methicillin resistant Staphylococcus aureus (MRSA) isolates harboring mecC gene belong to clonal complex CC130. This lineage has traditionally been regarded as animal-associated as it lacks the human specific immune evasion...
Development of a quantitative methodology to assess the impacts of urban transport interventions and related noise on well-being
Matthias Braubach, Myriam Tobollik, Pierpaolo Mudu, Rosemary Hiscock, Dimitris Chapizanis, Denis A. Sarigiannis, Menno Keuken, Laura Perez, Marco Martuzzi
May 26, 2015
Well-being impact assessments of urban interventions are a difficult challenge, as there is no agreed methodology and scarce evidence on the relationship between environmental conditions and well-being. The European Union...
climate change Greenhouse gas impact assessment Mitigation Noise transport Urban policies well-being /dk/atira/pure/subjectarea/asjc/2700/2739 name=Public Health, Environmental and Occupational Health /dk/atira/pure/subjectarea/asjc/2300/2307 name=Health, Toxicology and Mutagenesis /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being /dk/atira/pure/sustainabledevelopmentgoals/climate_action name=SDG 13 - Climate Action
Cell-to-cell heterogeneity in Sox2 and Bra expression guides progenitor motility and destiny
Michèle Romanos, Guillaume Allio, Myriam Roussigné, Léa Combres, Nathalie Escalas, Cathy Soula, François Médevielle, Benjamin Steventon, Ariane Trescases, Bertrand Bénazéraf
Oct 05, 2021
Although cell-to-cell heterogeneity in gene and protein expression within cell populations has been widely documented, we know little about its biological functions. By studying progenitors of the posterior region of bird...
BAP1/ASXL complex modulation regulates epithelial-mesenchymal transition during trophoblast differentiation and invasion.
Vicente Perez-Garcia, Georgia Lea, Pablo Lopez-Jimenez, Hanneke Okkenhaug, Graham J Burton, Ashley Moffett, Margherita Y Turco, Myriam Hemberger
Sep 05, 2021
Normal function of the placenta depends on the earliest developmental stages when trophoblast cells differentiate and invade into the endometrium to establish the definitive maternal-fetal interface. Previously, we identified...
CRISPR gene editing developmental biology Epithelial-Mesenchymal Transition human MOUSE Placenta Regenerative Medicine stem cell self-renewal Stem Cells trophoblast trophoblast invasion Animals Cell Differentiation Epithelial-Mesenchymal Transition Gene Expression Regulation Humans Mice Repressor Proteins Trophoblasts Tumor Suppressor Proteins Ubiquitin Thiolesterase
Flips, dualities and symmetry enhancements
Abstract
We present various 4d $$ \mathcal{N} $$
ZFP57 regulation of transposable elements and gene expression within and beyond imprinted domains
Hui Shi, Ruslan Strogantsev, Nozomi Takahashi, Anastasiya Kazachenka, Matthew C. Lorincz, Myriam Hemberger, Anne C. Ferguson-Smith
Aug 08, 2020
Abstract: Background: KRAB zinc finger proteins (KZFPs) represent one of the largest families of DNA-binding proteins in vertebrate genomes and appear to have evolved to silence transposable elements (TEs) including endogenous...
BAP1/ASXL complex modulation regulates epithelial-mesenchymal transition during trophoblast differentiation and invasion
Vicente Perez-Garcia, Georgia Lea, Pablo Lopez-Jimenez, Hanneke Okkenhaug, Graham J Burton, Ashley Moffett, Margherita Y Turco, Myriam Hemberger
Jun 25, 2021
Normal function of the placenta depends on the earliest developmental stages when trophoblast cells differentiate and invade into the endometrium to establish the definitive maternal-fetal interface. Previously, we identified...
Decidualisation and placentation defects are a major cause of age-related reproductive decline.
Laura Woods, Vicente Perez-Garcia, Jens Kieckbusch, Xiaoqiu Wang, Francesco DeMayo, Francesco Colucci, Myriam Hemberger
Dec 17, 2018
ZFP57 regulation of transposable elements and gene expression within and beyond imprinted domains.
Hui Shi, Ruslan Strogantsev, Nozomi Takahashi, Anastasiya Kazachenka, Matthew C Lorincz, Myriam Hemberger, Anne C Ferguson-Smith
Jul 30, 2019
BACKGROUND: KRAB zinc finger proteins (KZFPs) represent one of the largest families of DNA-binding proteins in vertebrate genomes and appear to have evolved to silence transposable elements (TEs) including endogenous...
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