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The pharmaceutical solvent N-methyl-2-pyrollidone (NMP) attenuates inflammation through Krüppel-like factor 2 activation to reduce atherogenesis.
Marta Roche-Molina, Bryn Hardwick, Cristina Sanchez-Ramos, David Sanz-Rosa, Dirk Gewert, Francisco M Cruz, Andres Gonzalez-Guerra, Vicente Andres, Joaquin A Palma, Borja Ibanez, Grahame McKenzie, Juan A Bernal
Jul 28, 2021
N-methyl-2-pyrrolidone (NMP) is a versatile water-miscible polar aprotic solvent. It is used as a drug solubilizer and penetration enhancer in human and animal, yet its bioactivity properties remain elusive. Here, we report that...
Animals Anti-Inflammatory Agents Aorta Apoptosis Atherosclerosis Cell Adhesion Cell Line DNA Complementary Endothelial Cells Gene Expression Profiling Gene Library Human Umbilical Vein Endothelial Cells Humans Inflammation Kruppel-Like Transcription Factors Mice Mice Knockout ApoE Monocytes Pyrrolidinones RNA Small Interfering Solvents Tumor Necrosis Factor-alpha
The pharmaceutical solvent N-methyl-2-pyrollidone (NMP) attenuates inflammation through Krüppel-like factor 2 activation to reduce atherogenesis
Marta Roche-Molina, Bryn Hardwick, Cristina Sanchez-Ramos, David Sanz-Rosa, Dirk Gewert, Francisco M. Cruz, Andres Gonzalez-Guerra, Vicente Andres, Joaquin A. Palma, Borja Ibanez, Grahame McKenzie, Juan A. Bernal
Jul 15, 2020
Abstract: N-methyl-2-pyrrolidone (NMP) is a versatile water-miscible polar aprotic solvent. It is used as a drug solubilizer and penetration enhancer in human and animal, yet its bioactivity properties remain elusive. Here, we...
A Comparative Analysis of Deep Learning Approaches for Network Intrusion Detection Systems (N-IDSs)
Recently, due to the advance and impressive results of deep learning techniques in the fields of image recognition, natural language processing and speech recognition for various long-standing artificial intelligence (AI) tasks...
Published by: IGI Global Scientific Publishing
The neural basis of hot and cold cognition in depressed patients, unaffected relatives, and low-risk healthy controls
BACKGROUND: Modern cognitive neuropsychological models of depression posit that negatively biased emotional ("hot") processing confers risk for depression, while preserved executive function ("cold") cognition promotes...
Non-Lorentzian SU(1, n) Spacetime Symmetry In Various Dimensions
We discuss non-Lorentzian Lagrangian field theories in $2n-1$ dimensions that
admit an $SU(1,n)$ spacetime symmetry which includes a scaling transformation.
These can be obtained by a conformal compactification of a...
Exact properties of an integrated correlator in N = 4 SU( N ) SYM
Abstract: We present a novel expression for an integrated correlation function of four superconformal primaries in SU(N) N = 4 supersymmetric Yang-Mills (N = 4 SYM) theory. This integrated correlator, which is based on...
Factorisation of 3d N = 4 twisted indices and the geometry of vortex moduli space
We study the twisted indices of $\mathcal{N}=4$ supersymmetric gauge theories
in three dimensions on spatial $S^{2}$ with an angular momentum refinement. We
demonstrate factorisation of the index into holomorphic blocks for...
HONORING TORSEN N. WIESEL
The Rockefeller University
Jan 01, 0001
A Celebration in Honor of Torsten N. Wiesel: Entering his Tenth Decade
Published by: The Rockefeller University
Voltammetric Monitoring of a Solid-Liquid Phase Transition in N,N,N’,N’-Tetraoctyl-2,6-diamino-9,10-anthraquinone (TODAQ)
Sun Yhik Ahn, Thomas Forder, Matthew Jones, Richard Blackburn, Paul Fordred, Steven Bull, Frank Marken
Jan 31, 2020
Exploratory experiments on effects from a phase transition are reported for a low-melting microcrystalline anthraquinone (N,N,N′,N′-tetraoctyl-2,6-diamino-9,10-anthraquinone or TODAQ). Data for the solid-liquid phase...
Battery materials Calorimetry Melting point Phase Transition Plastic crystalline solids Triple phase boundary Voltammetry /dk/atira/pure/subjectarea/asjc/2500/2500 name=General Materials Science /dk/atira/pure/subjectarea/asjc/3100/3104 name=Condensed Matter Physics /dk/atira/pure/subjectarea/asjc/1600/1603 name=Electrochemistry /dk/atira/pure/subjectarea/asjc/2200/2208 name=Electrical and Electronic Engineering
On the appearance of nitrite anion in [PdX(OAc)L<sub>2</sub>] and [Pd(X)(C∧N)L] syntheses (X = OAc or NO<sub>2</sub>)
S E Bajwa, T E Storr, Lauren E Hatcher, T J Williams, C G Baumann, A C Whitwood, D R Allan, S J Teat, Paul R Raithby, I J S Fairlamb
May 01, 2012
Pd 3(OAc) 5NO 2, an impurity in "Pd(OAc) 2" {formally Pd 3(OAc) 6}, emerges as a serious issue in the synthesis of pure Pd II complexes derived from Pd(OAc) 2, for example in our C-H activation precatalyst, Pd(OAc) 2(pip) 2 (pip...
k-Root-n
Blockchains such as the bitcoin blockchain depend on reaching a global consensus on the distributed ledger; therefore, they suffer from well-known scalability problems. This paper proposes an algorithm that avoids...
Zvi Schreiber
Feb 08, 2020
Exact properties of an integrated correlator in N = 4 SU(N) SYM
Abstract
We present a novel expression for an integrated correlation function of four superconformal primaries in SU(N )...
Optimization-Driven Kernel and Deep Convolutional Neural Network for Multi-View Face Video Super Resolution
One of the major challenges faced by video surveillance is recognition from low-resolution videos or person identification. Image enhancement methods play a significant role in enhancing the resolution of the video. This article...
Published by: IGI Global Scientific Publishing
Local Limit Theorems for the Random Conductance Model and Applications to the Ginzburg–Landau $$\nabla \phi $$ Interface Model
Abstract We study a continuous-time random walk on$${\mathbb {Z}}^d$$
The N-terminal RASSF family
The RASSF (Ras-association domain family) has recently gained several new members and now contains ten proteins (RASSF1–10), several of which are potential tumour suppressors. The family can be split into two groups, the...
Voltammetric Monitoring of a Solid-Liquid Phase Transition in N,N,N’,N’-Tetraoctyl-2,6-diamino-9,10-anthraquinone (TODAQ)
Sun Yhik Ahn, Thomas Forder, Matthew Jones, Richard Blackburn, Paul Fordred, Steven Bull, Frank Marken
Jan 31, 2020
Exploratory experiments on effects from a phase transition are reported for a low-melting microcrystalline anthraquinone (N,N,N′,N′-tetraoctyl-2,6-diamino-9,10-anthraquinone or TODAQ). Data for the solid-liquid phase...
Battery materials Calorimetry Melting point Phase Transition Plastic crystalline solids Triple phase boundary Voltammetry /dk/atira/pure/subjectarea/asjc/2500/2500 name=General Materials Science /dk/atira/pure/subjectarea/asjc/3100/3104 name=Condensed Matter Physics /dk/atira/pure/subjectarea/asjc/1600/1603 name=Electrochemistry /dk/atira/pure/subjectarea/asjc/2200/2208 name=Electrical and Electronic Engineering
The N-terminal RASSF family
The RASSF (Ras-association domain family) has recently gained several new members and now contains ten proteins (RASSF1–10), several of which are potential tumour suppressors. The family can be split into two groups, the...
Dollfustrema durum n. sp. and Heterobucephalopsis perardua n. sp. (Digenea: Bucephalidae) from the giant moray eel, Gymnothorax javanicus (Bleeker) (Anguilliformes
Matthew J Nolan, Stephen S Curran, Terrence L Miller, Scott C Cutmore, Cinzia Cantacessi, Thomas H Cribb
Jul 16, 2015
On (n+1/2)-Engel groups
Let n be a positive integer. We say that a group G is an (n+1/2)-Engel group if it satisfies the law [ x, y n, x ] = 1. The variety of (n+1/2)-Engel groups lies between the varieties of n-Engel groups and (n+1) -Engel groups. In...
A Review of Spectrum Sensing Techniques Based on Machine Learning
This article presents a survey of current spectrum sensing (SS) research involving the application of image processing and deep learning techniques. This document includes approaches to narrowband, wideband, and cooperative SS....
Global Information Technology Computer Science and Information Technology Global Information Technology Physical Sciences and Engineering Business and Management
Published by: IGI Global Scientific Publishing
[Arg(6), D-Trp(7,9), N(me)Phe(8)]-substance P (6-11) (antagonist G) induces AP-1 transcription and sensitizes cells to chemotherapy.
[Arg(6), D-Trp(7,9), N(me)Phe(8)]-substance P (6-11) (antagonist G) inhibits small cell lung cancer (SCLC) growth and is entering Phase II clinical investigation for the treatment of SCLC. As well as acting as a neuropeptide...
Acetylcysteine Animals Antineoplastic Agents Antineoplastic Agents Phytogenic Apoptosis CHO Cells Carcinoma Small Cell Cell Division Cricetinae Drug Synergism Etoposide Free Radical Scavengers Glutathione Growth Inhibitors JNK Mitogen-Activated Protein Kinases Lipid Peroxidation Lung Neoplasms MAP Kinase Kinase 4 Mitogen-Activated Protein Kinase Kinases Oligopeptides Oxidation-Reduction Reactive Oxygen Species Stimulation Chemical Transcription Factor AP-1 Transcription Genetic Tumor Cells Cultured
Local Limit Theorems for the Random Conductance Model and Applications to the Ginzburg–Landau ∇ ϕ Interface Model
Abstract: We study a continuous-time random walk on Zd in an environment of random conductances taking values in (0, ∞). For a static environment, we extend the quenched local limit theorem to the case of a general speed...
Autism screening and conditional cash transfers in Chile
Andres Roman-Urrestarazu, Carolina Yáñez, Claudia López-Garí, Constanza Elgueta, Carrie Allison, Carol Brayne, Mónica Troncoso, Simon Baron-Cohen
May 11, 2021
Diagnosis of Autism Spectrum Conditions (ASC) can be an extended procedure since ASC tend to both vary greatly across individual symptoms and diagnostic pathways with serious challenges to opportune access and diagnosis in low...
On (n+1/2)-Engel groups
Let n be a positive integer. We say that a group G is an (n+1/2)-Engel group if it satisfies the law [ x, y n, x ] = 1. The variety of (n+1/2)-Engel groups lies between the varieties of n-Engel groups and (n+1) -Engel groups. In...
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