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Results: 150
Log-transformation improves the prognostic value of serial NT-proBNP levels in apparently stable pulmonary arterial hypertension.
Elaine Soon, Natalie J Doughty, Carmen M Treacy, Robert M Ross, Mark Toshner, Paul D Upton, Karen Sheares, Nicholas W Morrell, Joanna Pepke-Zaba
Aug 28, 2020
N-terminal pro B-type natriuretic peptide (NT-proBNP) is a product of cleavage of the cardiac prohormone pro B-type natriuretic peptide into its active form. It has proven to be a useful biomarker in left heart failure. However...
Primary care REFerral for EchocaRdiogram (REFER) in heart failure
Clare J Taylor, Andrea K Roalfe, Rachel Iles, FD Richard Hobbs, REFER investigators, P Barton, J Deeks, D McCahon, MR Cowie, G Sutton, RC Davis, J Mant, T McDonagh, L Tait
May 02, 2018
BACKGROUND: Symptoms of breathlessness, fatigue, and ankle swelling are common in general practice but deciding which patients are likely to have heart failure is challenging. AIM: To evaluate the performance of a clinical...
clinical decision rule Diagnostic Echocardiography General Practice Heart Failure Natriuretic Peptide Adult Aged Biomarkers Clinical Protocols Dyspnea Electrocardiography England fatigue Female Heart Failure Humans Male Middle Aged Natriuretic Peptide Brain Peptide Fragments Primary Health Care Prospective Studies ROC Curve Referral and Consultation Research Design
Sustained heavy drinking over 25 years is associated with increased N-terminal-pro-B-type natriuretic peptides in early old age
UNLABELLED: Heavy alcohol consumption is associated with an increased risk of heart failure. We sought to investigate whether levels of NT-proBNP differ by alcohol consumption profiles, both current drinking as well as...
Biomarker changes with systolic anterior motion of the mitral valve in cats with hypertrophic cardiomyopathy.
Joonbum Seo, Jessie Rosie Payne, Jose Novo Matos, Wesley Wynne Fong, David J Connolly, Virginia Luis Fuentes
Sep 23, 2021
BACKGROUND: N-terminal pro B-type natriuretic peptide (NT-proBNP) and cardiac troponin-I (cTnI) are biomarkers commonly evaluated in cats with suspected heart disease. Many cats with hypertrophic cardiomyopathy (HCM) have...
Reference exome data for Australian Aboriginal populations to support health-based research
Alexia L. Weeks, Heather A. D’Antoine, Melita McKinnon, Genevieve Syn, Dawn Bessarab, Ngiare Brown, Steven Y. C. Tong, Bo Reményi, Andrew Steer, Lesley-Ann Gray, Michael Inouye, Jonathan R. Carapetis, Jenefer M. Blackwell, Timo Lassmann
Feb 16, 2021
Abstract: Whole exome sequencing (WES) is a popular and successful technology which is widely used in both research and clinical settings. However, there is a paucity of reference data for Aboriginal Australians to underpin the...
Exploration of inositol 1,4,5-trisphosphate (IP3) regulated dynamics of N-terminal domain of IP3 receptor reveals early phase molecular events during receptor activation.
Inositol 1, 4, 5-trisphosphate (IP3) binding at the N-terminus (NT) of IP3 receptor (IP3R) allosterically triggers the opening of a Ca2+-conducting pore located ~100 Å away from the IP3-binding core (IBC). However, the precise...
The Arabidopsis thaliana N-recognin E3 ligase PROTEOLYSIS1 influences the immune response.
Christopher J Till, Jorge Vicente, Hongtao Zhang, Maria Oszvald, Michael J Deery, Victoria Pastor, Kathryn S Lilley, Rumiana V Ray, Frederica L Theodoulou, Michael J Holdsworth
Feb 24, 2020
N-degron pathways of ubiquitin-mediated proteolysis (formerly known as the N-end rule pathway) control the stability of substrate proteins dependent on the amino-terminal (Nt) residue. Unlike yeast or mammalian N-recognin E3...
Size-Exclusion Chromatography Separation Reveals That Vesicular and Non-Vesicular Small RNA Profiles Differ in Cell Free Urine.
Jenni Karttunen, Sarah E Stewart, Lajos Kalmar, Andrew J Grant, Fiona E Karet Frankl, Tim L Williams
Jul 07, 2021
Urinary extracellular vesicles (EVs) and their RNA cargo are a novel source of biomarkers for various diseases. We aimed to identify the optimal method for isolating small (<200 nm) EVs from human urine prior to small RNA...
Urine small RNA extracellular vesicles Cell-Free System Humans MicroRNAs ultrafiltration Ultracentrifugation Chromatography Gel
Published by: International journal of molecular sciences
The Arabidopsis thaliana N-recognin E3 ligase PROTEOLYSIS1 influences the immune response.
Christopher J Till, Jorge Vicente, Hongtao Zhang, Maria Oszvald, Michael J Deery, Victoria Pastor, Kathryn S Lilley, Rumiana V Ray, Frederica L Theodoulou, Michael J Holdsworth
Feb 02, 2020
N-degron pathways of ubiquitin-mediated proteolysis (formerly known as the N-end rule pathway) control the stability of substrate proteins dependent on the amino-terminal (Nt) residue. Unlike yeast or mammalian N-recognin E3...
Published by: Plant direct, volume 3, issue 12
Returning Thermal Advantage Instrument's DSC 2920 and SDT 2960 to Functioning Order
Ethan B Haldeman
Jan 01, 0001
Thermal Advantage (TA) Instruments DSC 2920 and SDT 2960 require a computer running Windows NT 2000 and an Industry Standard Architecture (ISA) expansion card to output and record data. Due to the lack of availability for this...
SDT 2960 DSC 2920 Windows NT 2000 Software TA Instruments Computer Sciences Physical Sciences and Mathematics Physics
Published by: Ursinus College
Mechanistic insights into non-coding Y RNA processing.
Martina Billmeier, Darrell Green, Adam E Hall, Carly Turnbull, Archana Singh, Ping Xu, Simon Moxon, Tamas Dalmay
May 01, 2022
Y RNAs (84-112 nt) are non-coding RNAs transcribed by RNA polymerase III and are characterized by a distinctive secondary structure. Human Y RNAs interact with the autoimmune proteins SSB and RO60 that together form a...
Oxidative stress in the developing brain
Emily J Camm, Deodata Tijsseling, Hans G Richter, Alexandra Adler, Jeremy A Hansell, Jan B Derks, Christine M Cross, Dino A Giussani
Sep 08, 2020
In premature infants, glucocorticoids ameliorate chronic lung disease, but have adverse effects on long-term neurological function. Glucocorticoid excess promotes free radical overproduction. We hypothesised that the adverse...
Mixing closures for conservation laws in stratified flows
A closure for shocks involving the mixing of the fluids in two-layer stratified flows is proposed. The closure maximizes the rate of mixing, treating the dynamical hydraulic equations and entropy conditions as constraints. This...
Microbiological evaluation of UV disinfection effectiveness in a specialist cystic fibrosis clinic.
O Allen, L Jadkauskaite, NT Shafi, A Jackson, V Athithan, Y-D Chiu, Evans Ies, RA Floto, CS Haworth
Jun 27, 2019
The aim of the study was to evaluate the impact of manual cleaning and manual cleaning followed by Ultraviolet-C disinfection on the colony forming units of bacteria retrievable from equipment and surfaces within clinic rooms...
The minus sign in the first law of de Sitter horizons
Abstract
Due to a well-known, but curious, minus sign in the Gibbons-Hawking first law for the static patch of de Sitter space, the entropy of the...
Size-Exclusion Chromatography Separation Reveals That Vesicular and Non-Vesicular Small RNA Profiles Differ in Cell Free Urine
Jenni Karttunen, Sarah E. Stewart, Lajos Kalmar, Andrew J. Grant, Fiona E. Karet Frankl, Tim L. Williams
May 06, 2021
Urinary extracellular vesicles (EVs) and their RNA cargo are a novel source of biomarkers for various diseases. We aimed to identify the optimal method for isolating small (200 nm) EVs from human urine prior to small RNA...
Reference exome data for Australian Aboriginal populations to support health-based research.
Alexia L Weeks, Heather A D'Antoine, Melita McKinnon, Genevieve Syn, Dawn Bessarab, Ngiare Brown, Steven YC Tong, Bo Reményi, Andrew Steer, Lesley-Ann Gray, Michael Inouye, Jonathan R Carapetis, Jenefer M Blackwell, Timo Lassmann
May 20, 2020
Whole exome sequencing (WES) is a popular and successful technology which is widely used in both research and clinical settings. However, there is a paucity of reference data for Aboriginal Australians to underpin the...
Reference exome data for Australian Aboriginal populations to support health-based research
Alexia L. Weeks, Heather A. D’Antoine, Melita McKinnon, Genevieve Syn, Dawn Bessarab, Ngiare Brown, Steven Y. C. Tong, Bo Reményi, Andrew Steer, Lesley-Ann Gray, Michael Inouye, Jonathan R. Carapetis, Jenefer M. Blackwell, Timo Lassmann
Apr 29, 2021
Abstract: Whole exome sequencing (WES) is a popular and successful technology which is widely used in both research and clinical settings. However, there is a paucity of reference data for Aboriginal Australians to underpin the...
Size-Exclusion Chromatography Separation Reveals That Vesicular and Non-Vesicular Small RNA Profiles Differ in Cell Free Urine.
Jenni Karttunen, Sarah E Stewart, Lajos Kalmar, Andrew J Grant, Fiona E Karet Frankl, Tim L Williams
May 03, 2021
Urinary extracellular vesicles (EVs) and their RNA cargo are a novel source of biomarkers for various diseases. We aimed to identify the optimal method for isolating small (<200 nm) EVs from human urine prior to small RNA...
Resting state EEG power spectrum and functional connectivity in autism
Pilar Garcés, Sarah Baumeister, Luke Mason, Christopher H Chatham, Stefan Holiga, Juergen Dukart, Emily JH Jones, Tobias Banaschewski, Simon Baron-Cohen, Sven Bölte, Jan K Buitelaar, Sarah Durston, Bob Oranje, Antonio M Persico, Christian F Beckmann, Thomas Bougeron, Flavio Dell'Acqua, Christine Ecker, Carolin Moessnang, Tony Charman, Julian Tillmann, Declan GM Murphy, Mark Johnson, Eva Loth, Daniel Brandeis, Joerg F Hipp, EU-AIMS LEAP group authorship
Jun 29, 2022
BACKGROUND: Understanding the development of the neuronal circuitry underlying autism spectrum disorder (ASD) is critical to shed light into its etiology and for the development of treatment options. Resting state EEG provides a...
Mixing closures for conservation laws in stratified flows
A closure for shocks involving the mixing of the fluids in two-layer stratified flows is proposed. The closure maximizes the rate of mixing, treating the dynamical hydraulic equations and entropy conditions as constraints. This...
Hepatitis E in southern Vietnam
A Berto, HA Pham, TTN Thao, NHT Vy, SL Caddy, R Hiraide, NT Tue, I Goodfellow, JJ Carrique-Mas, GE Thwaites, S Baker, MF Boni, VIZIONS consortium
Apr 10, 2019
Viral pathogens account for a significant proportion of the burden of emerging infectious diseases in humans. The Wellcome Trust-Vietnamese Initiative on Zoonotic Infections (WT-VIZIONS) is aiming to understand the circulation...
Label-free electrical detection of DNA hybridization for the example of influenza virus gene sequences
Microarrays based on DNA-DNA hybridization are potentially useful for detecting and subtyping viruses but require fluorescence labeling and imaging equipment. We investigated a label-free electrical detection system using...
The Grizzly, January 22, 1991
Krishni Patrick, Sara Jacobson, Nicholas O. Berry, Mark Wilhelms, Hugh R. Clark, Kathleen Bowers
Jan 01, 0001
Student Activism Rises Across the Country Caught in the Crossfire: Iraqi Speaks on the War What to Look for in the Gulf War Taking War to Heart Limerick Prepared Saddam Hussein Must be Stopped Ruminations of a Confused...
Ursinus College Collegeville Pennsylvania newspaper Gulf War Limerick nuclear power plant Mohammed Latif Iraq Saddam Hussein cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
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