Search
Results: 618
Bioactivity assessment of natural compounds using machine learning models trained on target similarity between drugs.
Vinita Periwal, Stefan Bassler, Sergej Andrejev, Natalia Gabrielli, Kaustubh Raosaheb Patil, Athanasios Typas, Kiran Patil
May 09, 2022
Natural compounds constitute a rich resource of potential small molecule therapeutics. While experimental access to this resource is limited due to its vast diversity and difficulties in systematic purification, computational...
Unravelling metabolic cross-feeding in a yeast-bacteria community using 13 C-based proteomics.
Natalia Gabrielli, Christoniki Maga-Nteve, Eleni Kafkia, Mandy Rettel, Jakob Loeffler, Stephan Kamrad, Athanasios Typas, Kiran Raosaheb Patil
Feb 13, 2023
Cross-feeding is fundamental to the diversity and function of microbial communities. However, identification of cross-fed metabolites is often challenging due to the universality of metabolic and biosynthetic intermediates....
Bioactivity assessment of natural compounds using machine learning models trained on target similarity between drugs.
Vinita Periwal, Stefan Bassler, Sergej Andrejev, Natalia Gabrielli, Kaustubh Raosaheb Patil, Athanasios Typas, Kiran Raosaheb Patil
May 26, 2022
Natural compounds constitute a rich resource of potential small molecule therapeutics. While experimental access to this resource is limited due to its vast diversity and difficulties in systematic purification, computational...
High-throughput ultrastructure screening using electron microscopy and fluorescent barcoding.
Yury S Bykov, Nir Cohen, Natalia Gabrielli, Hetty Manenschijn, Sonja Welsch, Petr Chlanda, Wanda Kukulski, Kiran R Patil, Maya Schuldiner, John AG Briggs
Mar 05, 2020
The Chinese Experience of Developing Cross-Border E-Commerce Under the “Belt and Road” Framework
Cross-border e-commerce is becoming the driver of digital globalization and is of strategic importance in the growth of world trade. Under the framework of the Belt and Road Initiative, China has released a number of guidelines...
Published by: IGI Global Scientific Publishing
The Learning Value of Personalization in Children's Reading Recommendation Systems
Natalia Kucirkova
Oct 01, 2019
This article critically reviews the personalization logic embedded in reading recommendation systems developed for 2- to 11-year-old children and its (dis)alignment with Papert's constructionist and socio-constructionist...
Published by: IGI Global Scientific Publishing
Audio vs. Video Conferencing for Language Learning
Natalia Barley
May 14, 2021
This chapter will trace recent trends in research on audio and video conferencing for language learning and teaching and outline the affordances and mediating effects of each platform that have communicative, socio-affective...
Published by: IGI Global Scientific Publishing
Advancing English Language Learners' Speaking Skills Using VoiceThread in Mobile Learning for Russian Tertiary Context
Maria Zemlyanova, Natalia Muravyeva, Svetlana Masterskikh, Lyudmila Shilova, Anna Shevtsova
Nov 01, 2021
This research examines the effectiveness of using the VoiceThread (VT) application (both web and mobile-based) for the development of oral English skills of Russian university students. The study involved 44 full-time bachelor...
Published by: IGI Global Scientific Publishing
The Antecedents of Satisfaction and Revisit Intention for Full-Service Restaurants
The purpose of this research is to identify the factors influencing customers' satisfaction and revisit intentions for full-service restaurants in Jakarta. The recent economic crisis is known to have had a great impact on...
Published by: IGI Global Scientific Publishing
Mobile Applications in Education
The purpose of the study is to consider the features of the use of mobile applications for the development of professional competencies, in particular cognitive skills, and their general impact on the effectiveness of learning....
Published by: IGI Global Scientific Publishing
Supramolecular catalysis by recognition-encoded oligomers
All key chemical transformations in biology are catalysed by linear oligomers. Catalytic properties could be programmed into synthetic oligomers in the same way as they are programmed into proteins, and an example of the...
Published by: Chemical science
Two-component assembly of recognition-encoded oligomers that form stable H-bonded duplexes.
A new family of recognition-encoded oligomers that form stable duplexes in chloroform have been prepared. Monomer building blocks composed of dialdehydes functionalised with either a trifluoromethylphenol or phosphine oxide...
Published by: Chemical science
Defective ? interferon production in leprosy reversal with antigen and interleukin 2
[No abstract available]
Published by: Rockefeller University
Indirect effects of bullying on school mathematics achievement in Chile
Students who experience bullying at school present different negative outcomes, including lower academic achievement. However, the process by which bullying is connected to academic achievement is not clear. Using the Trends in...
Defects in the NC2 repressor affect both canonical and non-coding RNA polymerase II transcription initiation in yeast.
BACKGROUND: The formation of the pre-initiation complex in eukaryotic genes is a key step in transcription initiation. The TATA-binding protein (TBP) is a universal component of all pre-initiation complexes for all kinds of RNA...
Global optimization of spin Hamiltonians with gain-dissipative systems.
Recently, several platforms were proposed and demonstrated a proof-of-principle for finding the global minimum of the spin Hamiltonians such as the Ising and XY models using gain-dissipative quantum and classical systems. The...
Parental attachment security and problematic internet use in children
Problematic Internet Use (PIU) is a growing problem among children. Insecure attachment has been associated with PIU and emotion dysregulation. Furthermore, there is evidence suggesting that maladaptive Cognitive Emotion...
catastrophizing other-blame Parent-child attachment Problematic internet use rumination self-blame /dk/atira/pure/subjectarea/asjc/2700/2735 name=Pediatrics, Perinatology, and Child Health /dk/atira/pure/subjectarea/asjc/3200/3203 name=Clinical Psychology /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Recruitment of endogenous CNS stem cells for regeneration in demyelinating disease.
Demyelinating diseases, such as multiple sclerosis (MS), are responsible for a significant portion of the neurological disability burden worldwide, especially in young adults. Demyelination can be followed by a spontaneous...
Drosophila p120-catenin is crucial for endocytosis of the dynamic E-cadherin-Bazooka complex.
Indirect effects of bullying on school mathematics achievement in Chile
Students who experience bullying at school present different negative outcomes, including lower academic achievement. However, the process by which bullying is connected to academic achievement is not clear. Using the Trends in...
End user engagement in refugee shelter design
Debate about participatory design (PD) has focussed considerably upon process. Factors such as facilitation skills and commitment to a participatory ethos have been highlighted as factors mediating stakeholder engagement....
Human Factors humanitarianism Interdisciplinarity participatory design Research Methods /dk/atira/pure/subjectarea/asjc/2200/2216 name=Architecture /dk/atira/pure/subjectarea/asjc/1200/1201 name=Arts and Humanities (miscellaneous) /dk/atira/pure/subjectarea/asjc/2200/2200 name=General Engineering /dk/atira/pure/subjectarea/asjc/3300/3300 name=General Social Sciences /dk/atira/pure/subjectarea/asjc/1700/1706 name=Computer Science Applications /dk/atira/pure/subjectarea/asjc/1700/1702 name=Artificial Intelligence /dk/atira/pure/sustainabledevelopmentgoals/peace_justice_and_strong_institutions name=SDG 16 - Peace, Justice and Strong Institutions
Deciphering the role of miR-71 in Echinococcus multilocularis early development in vitro.
Matías Gastón Pérez, Markus Spiliotis, Natalia Rego, Natalia Macchiaroli, Laura Kamenetzky, Nancy Holroyd, Marcela Alejandra Cucher, Klaus Brehm, Mara Cecilia Rosenzvit
Jan 13, 2020
Echinococcosis represents a major public health problem worldwide and is considered a neglected disease by the World Health Organization. The etiological agents are Echinococcus tapeworms, which display elaborate developmental...
|
|< |
< |
1 |