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Control and Context Are Central for People With Advanced Illness Experiencing Breathlessness
CONTEXT: Breathlessness is common and distressing in advanced illness. It is a challenge to assess, with few effective treatment options. To evaluate new treatments, appropriate outcome measures that reflect the concerns of...
To What Extent Do the NRS and CRQ Capture Change in Patients' Experience of Breathlessness in Advanced Disease? Findings From a Mixed-Methods Double-Blind Randomized Feasibility Trial.
Natasha Lovell, Simon Noah Etkind, Sabrina Bajwah, Matthew Maddocks, Irene Julie Higginson
Dec 21, 2020
CONTEXT: Chronic or refractory breathlessness is common and distressing. To evaluate new treatments, outcome measures that capture change in patients' experience are needed. OBJECTIVES: To explore the extent to which the...
breathlessness advanced disease outcome measure Randomized controlled trial Shortness of breath Aged Aged 80 and over Chronic Disease Double-Blind Method Dyspnea Feasibility Studies Female Heart Failure Humans Lung Diseases Interstitial Male Middle Aged Neoplasms Pulmonary Disease Chronic Obstructive Quality of life Severity of Illness Index Surveys and Questionnaires
Finding a 'new normal' following acute illness
Simon Noah Etkind, Natasha Lovell, Caroline Jane Nicholson, Irene J Higginson, Fliss Em Murtagh
Nov 26, 2020
Characteristics, Symptom Management, and Outcomes of 101 Patients With COVID-19 Referred for Hospital Palliative Care.
Natasha Lovell, Matthew Maddocks, Simon N Etkind, Katie Taylor, Irene Carey, Vandana Vora, Lynne Marsh, Irene J Higginson, Wendy Prentice, Polly Edmonds, Katherine E Sleeman
Dec 09, 2020
Hospital palliative care is an essential part of the COVID-19 response but data are lacking. We identified symptom burden, management, response to treatment, and outcomes for a case series of 101 inpatients with confirmed...
Business Model Innovation Through Digital Entrepreneurship
Aggregator business network models are quickly becoming critical enablers of digital transformation across various industries and are increasingly active in service start-ups such as online food delivery. With their innovative...
Published by: IGI Global Scientific Publishing
Prevalence of Latent Tuberculosis Infection among Hospital Workers in a Tertiary Care Referral Centre
According to the World Health Organization, more than 2 billion people in the world are latently infected with Mycobacterium tuberculosis.The goal of testing for latent Mycobacterium tuberculosis infection is to identify persons...
Published by: IJHS Medical Association
Prevalence of Latent Tuberculosis Infection among Hospital Workers in a Tertiary Care Referral Centre
According to the World Health Organization, more than 2 billion people in the world are latently infected with Mycobacterium tuberculosis.The goal of testing for latent Mycobacterium tuberculosis infection is to identify persons...
Published by: IJHS Medical Association
Green space, health and wellbeing
This essay examines the assumptions of green space use underpinning much existing green space and health research. It considers opportunities to move the field forward through exploring two often overlooked aspects of...
The theoretical and practical determination of clinical cut-offs for the British Sign Language versions of PHQ-9 and GAD-7.
BACKGROUND: The PHQ-9 and the GAD-7 assess depression and anxiety respectively. There are standardised, reliability-tested versions in BSL (British Sign Language) that are used with Deaf users of the IAPT service. The aim of...
What influenced people with chronic or refractory breathlessness and advanced disease to take part and remain in a drug trial? A qualitative study.
BACKGROUND: Recruitment and retention in clinical trials remains an important challenge, particularly in the context of advanced disease. It is important to understand what affects retention to improve trial quality, minimise...
breathlessness Palliative Care person-centred care Qualitative randomised controlled trial Recruitment Retention Aged Aged 80 and over Chronic Disease Double-Blind Method Dyspnea Feasibility Studies Female Heart Failure Humans Lung Diseases Interstitial Male Middle Aged motivation Neoplasms Patient Participation Pulmonary Disease Chronic Obstructive qualitative research Quality of life Severity of Illness Index Surveys and Questionnaires United Kingdom
A secreted protein of 15 kDa plays an important role in Phytophthora palmivora development and pathogenicity
Sittiporn Pettongkhao, Natasha Navet, Sebastian Schornack, Miaoying Tian, Nunta Churngchow
Feb 10, 2021
Abstract: Phytophthora palmivora is a destructive oomycete plant pathogen with a wide host range. So far, little is known about the factors governing its infection structure development and pathogenicity. From the culture...
Using 'sentinel' plants to improve early detection of invasive plant pathogens.
Infectious diseases of plants present an ongoing and increasing threat to international biosecurity, with wide-ranging implications. An important challenge in plant disease management is achieving early detection of invading...
Unravelling compulsory happiness in exile
Natasha Tanna
Jul 19, 2018
A number of feminist critics of Latin American women writers in exile have suggested that women in exile may flourish as they are freed from the traditional gender restrictions imposed on them in their home countries. In this...
Using 'sentinel' plants to improve early detection of invasive plant pathogens.
Infectious diseases of plants present an ongoing and increasing threat to international biosecurity, with wide-ranging implications. An important challenge in plant disease management is achieving early detection of invading...
Published by: PLoS computational biology
Secondary structure assignment that accurately reflects physical and evolutionary characteristics.
The stability of care preferences following acute illness
BACKGROUND: Patient preferences are integral to person-centred care, but preference stability is poorly understood in older people, who may experience fluctuant illness trajectories with episodes of acute illness. We aimed to...
The Multiple Faces of the Marmot
Mongolians have long known of the association between marmots and the plague. We examine their understanding of the marmot not only as a biological species that can harbour the plague, but also from a cosmological perspective as...
Early GP Leavers Interim Report
Published by: University of Bath
The stability of care preferences following acute illness
S. N. Etkind, N. Lovell, A. E. Bone, P. Guo, C. Nicholson, F. E. M. Murtagh, I. J. Higginson
Sep 29, 2020
Abstract: Background: Patient preferences are integral to person-centred care, but preference stability is poorly understood in older people, who may experience fluctuant illness trajectories with episodes of acute illness. We...
How many people will need palliative care in 2040? Past trends, future projections and implications for services.
BACKGROUND: Current estimates suggest that approximately 75% of people approaching the end-of-life may benefit from palliative care. The growing numbers of older people and increasing prevalence of chronic illness in many...
Chronic Disease Comorbidity Forecasting Health Services Needs and Demand Mortality Needs Assessment Palliative Care Adolescent Adult Aged Aged 80 and over Child Child Preschool Chronic Disease Delivery of Health Care Dementia England Female Forecasting Humans Infant Infant Newborn Male Middle Aged Palliative Care Population Growth prevalence Wales Young Adult
A prospective trial of the effects of isotretinoin on quality of life and depressive symptoms
Background Isotretinoin is an efficacious treatment for acne, but has been controversially linked with depression. Objectives This study aimed to examine the effects of isotretinoin on quality of life (QoL) and depression using...
Green space, health and wellbeing
This essay examines the assumptions of green space use underpinning much existing green space and health research. It considers opportunities to move the field forward through exploring two often overlooked aspects of...
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