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Murine Kupffer cells: mononuclear phagocytes deficient in the generation of reactive oxygen intermediates
Lepay, D.A., Nathan, C.F., Steinman, R.M., Murray, H.W., and Cohn, Z.A. Murine Kupffer cells: mononuclear phagocytes deficient in the generation of reactive oxygen intermediates. J. Exp. Med. 161: 1079-1096, 1985
Published by: The Rockefeller University Press
The application of a monolithic triphenylphosphine reagent for conducting Appel reactions in flow microreactors.
Kimberley A Roper, Heiko Lange, Anastasios Polyzos, Malcolm B Berry, Ian R Baxendale, Steven V Ley
Jun 17, 2021
Herein we describe the application of a monolithic triphenylphosphine reagent to the Appel reaction in flow-chemistry processing, to generate various brominated products with high purity and in excellent yields, and with no...
Towards brain-tissue-like biomaterials.
Many biomaterials have been developed which aim to match the elastic modulus of the brain for improved interfacing. However, other properties such as ultimate toughness, tensile strength, poroviscoelastic responses, energy...
Archives Moving From Dacus Library and Will Reopen on Jan. 2
Winthrop University
Jan 01, 0001
Researchers, scholars, genealogists and others are expected to flock to the archives to pore over its contents, which number more than six million items. Some of the most popular draws will be the 5,000-year-old cuneiform...
Published by: Winthrop University
SIFE Team Declared as 2012 Charlotte Regional Champions
Winthrop University
Jan 01, 0001
This makes the eighth straight year that Winthrop's team has taken first place at regionals. Team members are Deja Frederick, a senior integrated marketing communication major; Kayla Dugger, a junior digital information design...
Published by: Winthrop University
The application of a monolithic triphenylphosphine reagent for conducting Ramirez gem-dibromoolefination reactions in flow.
The application of a monolithic form of triphenylphosphine to the Ramirez gem-dibromoolefination reaction using flow chemistry techniques is reported. A variety of gem-dibromides were synthesised in high purity and excellent...
Genetic approaches to understand cellular responses to oxygen availability.
Oxygen-sensing mechanisms have evolved to allow organisms to respond and adapt to oxygen availability. In metazoans, oxygen-sensing is predominantly mediated by the hypoxia inducible factors (HIFs). These transcription factors...
Metabolic Regulation of Hypoxia-Inducible Transcription Factors
Hypoxia-inducible transcription factors (HIFs) facilitate cellular adaptations to low-oxygen environments. However, it is increasingly recognised that HIFs may be activated in response to metabolic stimuli, even when oxygen is...
A Multiscale Model for Solute Diffusion in Hydrogels.
Eneko Axpe, Doreen Chan, Giovanni S Offeddu, Yin Chang, David Merida, Hector Lopez Hernandez, Eric A Appel
Apr 20, 2020
The number of biomedical applications of hydrogels is increasing rapidly on account of their unique physical, structural, and mechanical properties. The utility of hydrogels as drug delivery systems or tissue engineering...
Energy Autonomous Sweat-Based Wearable Systems.
The continuous operation of wearable electronics demands reliable sources of energy, currently met through Li-ion batteries and various energy harvesters. These solutions are being used out of necessity despite potential safety...
Tail state mediated conduction in zinc tin oxide thinfilm phototransistors under below bandgap optical excitation.
We report on the appearance of a strong persistent photoconductivity (PPC) and conductor-like behaviour in zinc tin oxide (ZTO) thinfilm phototransistors. The active ZTO channel layer was prepared by remote plasma reactive...
Decoupled Associative and Dissociative Processes in Strong yet Highly Dynamic Host-Guest Complexes.
Eric A Appel, Frank Biedermann, Dominique Hoogland, Jesús del Barrio, Max D Driscoll, Sam Hay, David J Wales, Oren A Scherman
Nov 28, 2017
Kinetics and thermodynamics in supramolecular systems are intimately linked, yet both are independently important for application in sensing assays and stimuli-responsive switching/self-healing of materials. Host-guest...
Current therapy of granulomatosis with polyangiitis and microscopic polyangiitis
Duvuru Geetha, Cees Kallenberg, John H Stone, Alan D Salama, Gerald B Appel, George Duna, Paul Brunetta, David Jayne
Nov 24, 2020
Granulomatosis with polyangiitis and microscopic polyangiitis are anti-neutrophil cytoplasmic antibody-associated vasculitides (AAVs) that are prone to cycles of remission and relapse. The introduction of cytotoxic therapy has...
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