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Results: 12
Climatic shifts drove major contractions in avian latitudinal distributions throughout the Cenozoic.
Erin E Saupe, Alexander Farnsworth, Daniel J Lunt, Navjit Sagoo, Karen V Pham, Daniel J Field
May 09, 2019
Many higher level avian clades are restricted to Earth's lower latitudes, leading to historical biogeographic reconstructions favoring a Gondwanan origin of crown birds and numerous deep subclades. However, several such...
Whole-Genome Sequencing of Retinoblastoma Reveals the Diversity of Rearrangements Disrupting RB1 and Uncovers a Treatment-Related Mutational Signature.
Helen R Davies, Kevin D Broad, Zerrin Onadim, Elizabeth A Price, Xueqing Zou, Ibrahim Sheriff, Esin Kotiloğlu Karaa, Irene Scheimberg, M Ashwin Reddy, Mandeep S Sagoo, Shin-Ichi Ohnuma, Serena Nik-Zainal
Feb 17, 2021
The development of retinoblastoma is thought to require pathological genetic changes in both alleles of the RB1 gene. However, cases exist where RB1 mutations are undetectable, suggesting alternative pathways to malignancy. We...
The DANTE trial protocol
Oliver Coen, Pippa Corrie, Helen Marshall, Ruth Plummer, Christian Ottensmeier, Jane Hook, Sue Bell, Gurdeep S. Sagoo, David Meads, Janine Bestall, Galina Velikova, Ferdia A. Gallagher, Alexandra Smith, Helen Howard, Ellen Mason, Eszter Katona, Shobha Silva, Michelle Collinson, Simon Rodwell, Sarah Danson
Jul 02, 2021
Abstract: Background: Immunotherapy is revolutionising the treatment of patients diagnosed with melanoma and other cancers. The first immune checkpoint inhibitor, ipilimumab (targeting cytotoxic T-lymphocyte-associated antigen 4...
The DANTE trial protocol
Oliver Coen, Pippa Corrie, Helen Marshall, Ruth Plummer, Christian Ottensmeier, Jane Hook, Sue Bell, Gurdeep S Sagoo, David Meads, Janine Bestall, Galina Velikova, Ferdia A Gallagher, Alexandra Smith, Helen Howard, Ellen Mason, Eszter Katona, Shobha Silva, Michelle Collinson, Simon Rodwell, Sarah Danson
Aug 02, 2021
Background
Immunotherapy is revolutionising the treatment of patients diagnosed with melanoma and other cancers. The first immune checkpoint inhibitor, ipilimumab (targeting cytotoxic T-lymphocyte-associated antigen 4...
Safety Immunotherapy Quality of life EFFICACY Metastatic melanoma schedule Anti-PD-1 checkpoint inhibitor
Published by: BMC cancer
Whole-Genome Sequencing of Retinoblastoma Reveals the Diversity of Rearrangements Disrupting RB1 and Uncovers a Treatment-Related Mutational Signature
Helen R. Davies, Kevin D. Broad, Zerrin Onadim, Elizabeth A. Price, Xueqing Zou, Ibrahim Sheriff, Esin Kotiloğlu Karaa, Irene Scheimberg, M. Ashwin Reddy, Mandeep S. Sagoo, Shin-Ichi Ohnuma, Serena Nik-Zainal
Feb 12, 2021
The development of retinoblastoma is thought to require pathological genetic changes in both alleles of the RB1 gene. However, cases exist where RB1 mutations are undetectable, suggesting alternative pathways to malignancy. We...
Two Secreted Proteoglycans, Activators of Urothelial Cell–Cell Adhesion, Negatively Contribute to Bladder Cancer Initiation and Progression
Vasiliki Papadaki, Ken Asada, Julie K. Watson, Toshiya Tamura, Alex Leung, Jack Hopkins, Margaret Dellett, Noriaki Sasai, Hongorzul Davaapil, Serena Nik-Zainal, Rebecca Longbottom, Makoto Nakakido, Ryo Torii, Abhi Veerakumarasivam, Syuzo Kaneko, Mandeep S. Sagoo, Gillian Murphy, Akihisa Mitani, Kohei Tsumoto, John D. Kelly, Ryuji Hamamoto, Shin-Ichi Ohnuma
Nov 14, 2020
Osteomodulin (OMD) and proline/arginine-rich end leucine repeat protein (PRELP) are secreted extracellular matrix proteins belonging to the small leucine-rich proteoglycans family. We found that OMD and PRELP were specifically...
The DANTE trial protocol
Oliver Coen, Pippa Corrie, Helen Marshall, Ruth Plummer, Christian Ottensmeier, Jane Hook, Sue Bell, Gurdeep S Sagoo, David Meads, Janine Bestall, Galina Velikova, Ferdia A Gallagher, Alexandra Smith, Helen Howard, Ellen Mason, Eszter Katona, Shobha Silva, Michelle Collinson, Simon Rodwell, Sarah Danson
Sep 05, 2021
BACKGROUND: Immunotherapy is revolutionising the treatment of patients diagnosed with melanoma and other cancers. The first immune checkpoint inhibitor, ipilimumab (targeting cytotoxic T-lymphocyte-associated antigen 4...
Alternatives to Student Outbound Mobility-Improving Students' Cultural Competency Skills Online to Improve Global Health Without Travel.
Anette Wu, Vinay Maddula, Jasmine Singh, Mandeep Gill Sagoo, Chung-Liang Chien, Richard Wingate, Heike Kielstein, Hannes Traxler, Cecilia Brassett, Jens Waschke, Fransziska Vielmuth, Takeshi Sakurai, Mina Zeroual, Jorgen Olsen, Salma El-Batti, Suvi Viranta-Kovanen, Shuji Kitahara, Kevin Keay, Carol Kunzel, Paulette Bernd, Geoffroy PJC Noël
Jul 28, 2021
INTRODUCTION: Student outbound mobility is a major element in internationalization of medical education and global health education. However, this approach is often criticized, as it is inherently inequitable....
The Anatomy Course During COVID-19
Anette Wu, Que Yun Xiao, Sean McWatt, Rachel Utomo, Austin Talis, Kerstin Saraci, Cecilia Brassett, Mandeep Gill Sagoo, Richard Wingate, Chung-Liang Chien, Hannes Traxler, Jens Waschke, Franziska Vielmuth, Yukari Yamada, Takeshi Sakurai, Mina Zeroual, Jorgen Olsen, Salma El-Batti, Suvi Viranta-Kovanen, Kevin Keay, William Stewart, Carol Kunzel, Paulette Bernd, Heike Kielstein, Geoffroy PJC Noël
Oct 14, 2022
BACKGROUND: During the COVID-19 pandemic, in-person cadaveric dissection laboratories for teaching anatomy were omitted by many schools around the world. While knowledge domains can be easily evaluated via remote exams...
Two Secreted Proteoglycans, Activators of Urothelial Cell-Cell Adhesion, Negatively Contribute to Bladder Cancer Initiation and Progression.
Vasiliki Papadaki, Ken Asada, Julie K Watson, Toshiya Tamura, Alex Leung, Jack Hopkins, Margaret Dellett, Noriaki Sasai, Hongorzul Davaapil, Serena Nik-Zainal, Rebecca Longbottom, Makoto Nakakido, Ryo Torii, Abhi Veerakumarasivam, Syuzo Kaneko, Mandeep S Sagoo, Gillian Murphy, Akihisa Mitani, Kohei Tsumoto, John D Kelly, Ryuji Hamamoto, Shin-Ichi Ohnuma
Dec 17, 2020
Osteomodulin (OMD) and proline/arginine-rich end leucine repeat protein (PRELP) are secreted extracellular matrix proteins belonging to the small leucine-rich proteoglycans family. We found that OMD and PRELP were specifically...
Initiating Students' Reflections on Life's Passing in the Anatomy Course - an International Observation at 14 Universities.
Anette Wu, Ann Chen Xi Yu, Cynthia Soledad Chang, Rahul Goel, Mandeep Gill Sagoo, Takeshi Sakurai, Suvi Viranta-Kovanen, Chung-Liang Chien, Hannes Traxler, Jens Waschke, Shuji Kitahara, Kevin Keay, Jorgen Olsen, Cecilia Brassett, Salma El Batti, Franziska Vielmuth, Anna Magdalena Sigmund, Mina Zeroual, Carol Kunzel, Paulette Bernd, Richard Wingate, Heike Kielstein, Geoffroy PJC Noel
Apr 23, 2021
BACKGROUND: Medical and dental students' feelings and thoughts about the topic of death and life's passing are often associated with learning in the gross anatomy course, when students begin working with a deceased body donor in...
New paradigms for BRCA1/BRCA2 testing in women with ovarian cancer
Inga Plaskocinska, Hannah Shipman, James Drummond, Edward Thompson, Vanessa Buchanan, Barbara Newcombe, Charlotte Hodgkin, Elisa Barter, Paul Ridley, Rita Ng, Suzanne Miller, Adela Dann, Victoria Licence, Hayley Webb, Li Tee Tan, Margaret Daly, Sarah Ayers, Barnaby Rufford, Helena Earl, Christine Parkinson, Timothy Duncan, Mercedes Jimenez-Linan, Gurdeep S Sagoo, Stephen Abbs, Nicholas Hulbert-Williams, Paul Pharoah, Robin Crawford, James D Brenton, Marc Tischkowitz
Apr 28, 2016
Clinical genetics Genetic screening/counselling Obstetrics and Gynaecology Adult Aged Aged 80 and over BRCA1 Protein BRCA2 Protein Carcinoma Ovarian Epithelial Female Genetic Predisposition to Disease Genetic Testing Germ-Line Mutation Humans Middle Aged Neoplasms Glandular and Epithelial Ovarian Neoplasms