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Results: 49
Human GPR42 is a transcribed multisite variant that exhibits copy number polymorphism and is functional when heterologously expressed.
FFAR3 (GPR41) is a G-protein coupled receptor for which short-chain fatty acids serve as endogenous ligands. The receptor is found on gut enteroendocrine L-cells, pancreatic β-cells, and sympathetic neurons, and is implicated in...
A 3.7 kb fragment of the mouse Scn10a gene promoter directs neural crest but not placodal lineage EGFP expression in a transgenic animal.
dorsal root ganglia nodose ganglion Pain Sodium Channels transgenic Animals Cell Lineage Female Gene Expression Regulation Developmental Green Fluorescent Proteins Male Mice Mice Transgenic NAV1.8 Voltage-Gated Sodium Channel Nerve Fibers Myelinated Neural Crest Neural Stem Cells Neurogenesis Organ Specificity Promoter Regions Genetic Sensory Receptor Cells
Rem2, a member of the RGK family of small GTPases, is enriched in nuclei of the basal ganglia.
Rem2 is a member of the RGK subfamily of RAS small GTPases. Rem2 inhibits high voltage activated calcium channels, is involved in synaptogenesis, and regulates dendritic morphology. Rem2 is the primary RGK protein expressed in...
Assessment of direct and indirect associations between children active school travel and environmental, household and child factors using structural equation modelling.
BACKGROUND: Active school travel (AST) is influenced by multiple factors including built and social environments, households and individual variables. A holistic theory such as Mitra's Behavioural Model of School Transportation...
Sociodemographic and Built Environment Associates of Travel to School by Car among New Zealand Adolescents
Sandra Mandic, Erika Ikeda, Tom Stewart, Nicholas Garrett, Debbie Hopkins, Jennifer S. Mindell, El Shadan Tautolo, Melody Smith
Dec 10, 2020
Travelling to school by car diminishes opportunities for physical activity and contributes to traffic congestion and associated noise and air pollution. This meta-analysis examined sociodemographic characteristics and built...
Features of effective staff training programmes within school-based interventions targeting student activity behaviour
Abstract
Background
Evaluations of school-based activity behaviour interventions suggest limited effectiveness on students’...
Mairead Ryan, Olivia Alliott, Erika Ikeda, Jian’an Luan, Riikka Hofmann, Esther van Sluijs
Sep 25, 2022
Tracing the cellular basis of islet specification in mouse pancreas.
Magdalena K Sznurkowska, Edouard Hannezo, Roberta Azzarelli, Lemonia Chatzeli, Tatsuro Ikeda, Shosei Yoshida, Anna Philpott, Benjamin D Simons
Sep 16, 2020
Animals Cell Differentiation Cell Lineage Computer Simulation Embryo Mammalian Embryonic Development Female Genes Reporter Glucagon-Secreting Cells Imaging Three-Dimensional Insulin-Secreting Cells Luminescent Proteins Male Mice Mice Transgenic Microscopy Confocal Models Animal Models Biological Organogenesis Pancreas Stem Cells
Tracing the cellular basis of islet specification in mouse pancreas
Magdalena K. Sznurkowska, Edouard Hannezo, Roberta Azzarelli, Lemonia Chatzeli, Tatsuro Ikeda, Shosei Yoshida, Anna Philpott, Benjamin D. Simons
Oct 07, 2021
Abstract: Pancreatic islets play an essential role in regulating blood glucose level. Although the molecular pathways underlying islet cell differentiation are beginning to be resolved, the cellular basis of islet morphogenesis...
Visualising Combined Time Use Patterns of Children's Activities and Their Association with Weight Status and Neighbourhood Context.
Jinfeng Zhao, Lisa Mackay, Kevin Chang, Suzanne Mavoa, Tom Stewart, Erika Ikeda, Niamh Donnellan, Melody Smith
Jan 06, 2020
Compositional data techniques are an emerging method in physical activity research. These techniques account for the complexities of, and interrelationships between, behaviours that occur throughout a day (e.g., physical...
Associations between Children's Physical Activity and Neighborhood Environments Using GIS
Melody Smith, Suzanne Mavoa, Erika Ikeda, Kamyar Hasanzadeh, Jinfeng Zhao, Tiina E Rinne, Niamh Donnellan, Marketta Kyttä, Jianqiang Cui
Mar 18, 2022
Regular participation in physical activity is essential for children's physical, mental, and cognitive health. Neighborhood environments may be especially important for children who are more likely to spend time in the...
Tracing the cellular basis of islet specification in mouse pancreas
Magdalena K. Sznurkowska, Edouard Hannezo, Roberta Azzarelli, Lemonia Chatzeli, Tatsuro Ikeda, Shosei Yoshida, Anna Philpott, Benjamin D. Simons
Oct 07, 2020
Abstract: Pancreatic islets play an essential role in regulating blood glucose level. Although the molecular pathways underlying islet cell differentiation are beginning to be resolved, the cellular basis of islet morphogenesis...
Metabolomics Identifies Metabolic Markers of Maturation in Human Pluripotent Stem Cell-Derived Cardiomyocytes.
Vijesh J Bhute, Xiaoping Bao, Kaitlin K Dunn, Kylie R Knutson, Eric C McCurry, Gyuhyung Jin, Wei-Hua Lee, Sarah Lewis, Akihiro Ikeda, Sean P Palecek
Jun 20, 2018
Cardiovascular disease is a leading cause of death worldwide. Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) hold immense clinical potential and recent studies have enabled generation of virtually pure hPSC-CMs...
Sociodemographic and Built Environment Associates of Travel to School by Car among New Zealand Adolescents
Sandra Mandic, Erika Ikeda, Tom Stewart, Nicholas Garrett, Debbie Hopkins, Jennifer S Mindell, El Shadan Tautolo, Melody Smith
Jan 07, 2021
Travelling to school by car diminishes opportunities for physical activity and contributes to traffic congestion and associated noise and air pollution. This meta-analysis examined sociodemographic characteristics and built...
Cross-sectional and longitudinal associations of active travel, organised sport and physical education with accelerometer-assessed moderate-to-vigorous physical activity in young people
Connectivity Gradient in the Human Left Inferior Frontal Gyrus
Takuro Nakae, Riki Matsumoto, Takeharu Kunieda, Yoshiki Arakawa, Katsuya Kobayashi, Akihiro Shimotake, Yukihiro Yamao, Takayuki Kikuchi, Toshihiko Aso, Masao Matsuhashi, Kazumichi Yoshida, Akio Ikeda, Ryosuke Takahashi, Matthew A Lambon Ralph, Susumu Miyamoto
Mar 11, 2020
In the dual-stream model of language processing, the exact connectivity of the ventral stream to the anterior temporal lobe remains elusive. To investigate the connectivity between the inferior frontal gyrus (IFG) and the...
Results from New Zealand's 2018 Report Card on Physical Activity for Children and Youth.
Melody Smith, Erika Ikeda, Erica Hinckson, Scott Duncan, Ralph Maddison, Kim Meredith-Jones, Caroline Walker, Sandra Mandic
Jan 06, 2020
In New Zealand (NZ), 88% of health loss is now caused by non-communicable diseases, in part attributed to low levels of physical activity (PA) and high levels of inactivity, and the downstream impacts of these, including...
Dynamic 13C Flux Analysis Captures the Reorganization of Adipocyte Glucose Metabolism in Response to Insulin.
Lake-Ee Quek, James R Krycer, Satoshi Ohno, Katsuyuki Yugi, Daniel J Fazakerley, Richard Scalzo, Sarah D Elkington, Ziwei Dai, Akiyoshi Hirayama, Satsuki Ikeda, Futaba Shoji, Kumi Suzuki, Jason W Locasale, Tomoyoshi Soga, David E James, Shinya Kuroda
Apr 06, 2020
Cellular metabolism is dynamic, but quantifying non-steady metabolic fluxes by stable isotope tracers presents unique computational challenges. Here, we developed an efficient 13C-tracer dynamic metabolic flux analysis...
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