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In silico identification of Drosophila melanogaster genes encoding RNA polymerase subunits.
Three highly conserved, multisubunit RNA polymerase (RNAP) enzymes, RNAPs I, II, and III, transcribe the eukaryotic nuclear genome (reviewed by Cramer et al. 2008, Vannini and Cramer 2012, Griesenbeck et al. 2017, Cramer 2019)....
Published by: MicroPubl Biol
Presymptomatic white matter integrity loss in familial frontotemporal dementia in the GENFI cohort
Lize C Jiskoot, Martina Bocchetta, Jennifer M Nicholas, David M Cash, David Thomas, Marc Modat, Sebastien Ourselin, Serge ARB Rombouts, Elise GP Dopper, Lieke H Meeter, Jessica L Panman, Rick van Minkelen, Emma L van der Ende, Laura Donker Kaat, Yolande AL Pijnenburg, Barbara Borroni, Daniela Galimberti, Mario Masellis, Maria Carmela Tartaglia, James Rowe, Caroline Graff, Fabrizio Tagliavini, Giovanni B Frisoni, Robert Laforce, Elizabeth Finger, Alexandre de Mendonça, Sandro Sorbi, Genetic Frontotemporal dementia Initiative (GENFI), Janne M Papma, John C van Swieten, Jonathan D Rohrer
Oct 10, 2018
OBJECTIVE: We aimed to investigate mutation-specific white matter (WM) integrity changes in presymptomatic and symptomatic mutation carriers of the C9orf72,MAPT, and GRN mutations by use of diffusion-weighted imaging within the...