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Results: 79
High-throughput bacterial SNP typing identifies distinct clusters of Salmonella Typhi causing typhoid in Nepalese children.
Kathryn E Holt, Stephen Baker, Sabina Dongol, Buddha Basnyat, Neelam Adhikari, Stephen Thorson, Anoop S Pulickal, Yajun Song, Julian Parkhill, Jeremy J Farrar, David R Murdoch, Dominic F Kelly, Andrew J Pollard, Gordon Dougan
Sep 06, 2019
BACKGROUND: Salmonella Typhi (S. Typhi) causes typhoid fever, which remains an important public health issue in many developing countries. Kathmandu, the capital of Nepal, is an area of high incidence and the pediatric...
Bacterial Proteins Bacterial Typing Techniques Child Child Preschool Cluster Analysis DNA Gyrase DNA Bacterial Drug Resistance Bacterial Female Genotype Haplotypes High-Throughput Screening Assays Humans Infant Male molecular epidemiology Nepal Polymorphism Single Nucleotide Salmonella typhi Typhoid Fever
Laboratory and molecular surveillance of paediatric typhoidal Salmonella in Nepal
Carl D Britto, Zoe A Dyson, Sebastian Duchene, Michael J Carter, Meeru Gurung, Dominic F Kelly, David R Murdoch, Imran Ansari, Stephen Thorson, Shrijana Shrestha, Neelam Adhikari, Gordon Dougan, Kathryn E Holt, Andrew J Pollard
Sep 08, 2018
BACKGROUND: Children are substantially affected by enteric fever in most settings with a high burden of the disease, including Nepal. However pathogen population structure and transmission dynamics are poorly delineated in young...
A Deadline-Constrained Time-Cost-Effective Salp Swarm Algorithm for Resource Optimization in Cloud Computing
Nowadays, Cloud Computing has become the most attractive platform, which provides anything as a Service (XaaS). Many applications may be developed and run on the cloud without worrying about platforms. It is a big challenge to...
Published by: IGI Global Scientific Publishing
Melanoma Detection From Lesion Images Using Optimized Features Selected by Metaheuristic Algorithms
This paper deals with a simple but efficient method for detection of deadly malignant melanoma with optimized hand-crafted feature sets selected by three alternative metaheuristic algorithms, namely Particle Swarm Optimization...
Published by: IGI Global Scientific Publishing
A Hybrid Approach to Discover Entity Synonyms
A major part of the current web information retrieval involves the fulfilment of people's daily needs based upon finding entities involving movies, events, persons, places, concepts, etc. The trend has been the outcome of the...
Published by: IGI Global Scientific Publishing
Competing chemical and hydrodynamic interactions in autophoretic colloidal suspensions.
At the surfaces of autophoretic colloids, slip velocities arise from local chemical gradients that are many-body functions of particle configuration and activity. For rapid chemical diffusion, coupled with slip-induced...
Internal friction controls active ciliary oscillations near the instability threshold.
Ciliary oscillations driven by molecular motors cause fluid motion at micron scale. Stable oscillations require a substantial source of dissipation to balance the energy input of motors. Conventionally, it stems from external...
Antecedents to the Adoption of Digital Marketing by Start-Ups Under Startup-India and E-Governance Initiatives
India is witnessing a dual transformation marked by technological advancements and a surge in entrepreneurial activity following the launch of various e-governance schemes and the Startup India program. However, the high failure...
Published by: IGI Global Scientific Publishing
Chemical profiling of DNA G-quadruplex-interacting proteins in live cells.
Xiaoyun Zhang, Jochen Spiegel, Sergio Martínez Cuesta, Santosh Adhikari, Shankar Balasubramanian
Aug 02, 2021
DNA-protein interactions regulate critical biological processes. Identifying proteins that bind to specific, functional genomic loci is essential to understand the underlying regulatory mechanisms on a molecular level. Here we...
Published by: Nature chemistry
Controlled Optofluidic Crystallization of Colloids Tethered at Interfaces.
We report experiments that show rapid crystallization of colloids tethered to an oil-water interface in response to laser illumination. This light-induced transition is due to a combination of long-ranged thermophoretic pumping...
A new Himalayan crisis? Exploring transformative resilience pathways
This paper demonstrates that a new crisis has emerged in the Himalayas in recent years, as five decades of well-intentioned policy responses failed to tackle escalating environment and development challenges. It then suggests...
Impact of the announcement and implementation of the UK Soft Drinks Industry Levy on sugar content, price, product size and number of available soft drinks in the UK, 2015-19
Peter Scarborough, Vyas Adhikari, Richard A Harrington, Ahmed Elhussein, Adam Briggs, Mike Rayner, Jean Adams, Steven Cummins, Tarra Penney, Martin White
Jan 09, 2020
BACKGROUND: Dietary sugar, especially in liquid form, increases risk of dental caries, adiposity, and type 2 diabetes. The United Kingdom Soft Drinks Industry Levy (SDIL) was announced in March 2016 and implemented in April 2018...
Effect of Light & Colour on Shade Selection
Now a day’s dental restoration is consolidated around three mainstays: The use of non-metallic materials, such as composite resins and ceramics; adhesion to dental structures; and achieving a natural cosmetic...
Published by: IJHS Medical Association
Effect of Light & Colour on Shade Selection
Now a day’s dental restoration is consolidated around three mainstays: The use of non-metallic materials, such as composite resins and ceramics; adhesion to dental structures; and achieving a natural cosmetic...
Published by: IJHS Medical Association
Structure and Piezoelectricity Due to B Site Cation Variation in AB<sup>n+</sup>Cl<sub>n+2</sub>Hybrid Histammonium Chlorometallate Materials
Michael Wells, Jacob Hempel, Santosh Adhikari, Qingping Wang, Daniel Allen, Alison Costello, Chris Bowen, Sean Parkin, Christopher Sutton, Aron J. Huckaba
Nov 07, 2022
To provide new insights for understanding the influence of B site cations on the structure in chlorometallate materials of the form ABn+Cln+2, we report novel organic-inorganic hybrid metallates (OIHMs) incorporating...
G-quadruplexes are transcription factor binding hubs in human chromatin
Jochen Spiegel, Sergio Martínez Cuesta, Santosh Adhikari, Robert Hänsel-Hertsch, David Tannahill, Shankar Balasubramanian
Apr 23, 2021
Abstract: Background: The binding of transcription factors (TF) to genomic targets is critical in the regulation of gene expression. Short, double-stranded DNA sequence motifs are routinely implicated in TF recruitment, but many...
Prediction of Piezoelectric Tile Performance in Flat and Mountainous Terrains Through Deep Neural Network
Jitendra Adhikari, Kamalpreet Singh, Anjani Kumar Sagar, Vikki Kumar Sharma, Rajeev Kumar, Satish Chandra Jain
Sep 13, 2023
Piezoelectric tiles harvest mechanical vibrations and convert them into electrical energy, making them an attractive energy-harvesting technology. However, their performance is heavily influenced by the terrain where they are...
Bayesian inference across multiple models suggests a strong increase in lethality of COVID-19 in late 2020 in the UK.
Patrick Pietzonka, Erik Brorson, William Bankes, Michael E Cates, Robert Jack, Ronojoy Adhikari
Nov 24, 2021
We apply Bayesian inference methods to a suite of distinct compartmental models of generalised SEIR type, in which diagnosis and quarantine are included via extra compartments. We investigate the evidence for a change in...
Bayesian inference across multiple models suggests a strong increase in lethality of COVID-19 in late 2020 in the UK.
Patrick Pietzonka, Erik Brorson, William Bankes, Michael E Cates, Robert L Jack, Ronojoy Adhikari
Jan 07, 2022
We apply Bayesian inference methods to a suite of distinct compartmental models of generalised SEIR type, in which diagnosis and quarantine are included via extra compartments. We investigate the evidence for a change in...
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