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A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns.
Wei Jiao, Gurnit Atwal, Paz Polak, Rosa Karlic, Edwin Cuppen, PCAWG Tumor Subtypes and Clinical Translation Working Group, Alexandra Danyi, Jeroen de Ridder, Carla van Herpen, Martijn P Lolkema, Neeltje Steeghs, Gad Getz, Quaid D Morris, Lincoln D Stein, PCAWG Consortium
May 14, 2020
In cancer, the primary tumour's organ of origin and histopathology are the strongest determinants of its clinical behaviour, but in 3% of cases a patient presents with a metastatic tumour and no obvious primary. Here, as part of...
Repeatable group differences in the collective behaviour of stickleback shoals across ecological contexts.
Establishing how collective behaviour emerges is central to our understanding of animal societies. Previous research has highlighted how universal interaction rules shape collective behaviour, and that individual differences can...
Coping with strangers
Riva J Riley, Elizabeth R Gillie, Cat Horswill, Rufus A Johnstone, Neeltje J Boogert, Andrea Manica
Oct 31, 2019
Social groups composed of familiar individuals exhibit better coordination than unfamiliar groups; however, the ways familiarity contributes to coordination are poorly understood. Prior social experience probably allows...
Dose-response and transmission
Tamika J Lunn, Olivier Restif, Alison J Peel, Vincent J Munster, Emmie de Wit, Sanna Sokolow, Neeltje van Doremalen, Peter Hudson, Hamish McCallum
May 07, 2019
A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns
Wei Jiao, Rosa Karlic, Edwin Cuppen, Alexandra Danyi, Jeroen de Ridder, Carla van Herpen, Martijn P. Lolkema, Neeltje Steeghs, Quaid Morris, Fatima Al-Shahrour, Gurnit Atwal, Peter J. Bailey, Andrew V. Biankin, Paul C. Boutros, Peter J. Campbell, David K. Chang, Susanna L. Cooke, Vikram Deshpande, Bishoy M. Faltas, William C. Faquin, Levi Garraway, Gad Getz, Sean M. Grimmond, Syed Haider, Katherine A. Hoadley, Vera B. Kaiser, Rosa Karlić, Mamoru Kato, Kirsten Kübler, Alexander J. Lazar, Constance H. Li, David N. Louis, Adam Margolin, Sancha Martin, Hardeep K. Nahal-Bose, G. Petur Nielsen, Serena Nik-Zainal, Larsson Omberg, Christine P’ng, Marc D. Perry, Paz Polak, Esther Rheinbay, Mark A. Rubin, Colin A. Semple, Dennis C. Sgroi, Tatsuhiro Shibata, Reiner Siebert, Jaclyn Smith, Lincoln D. Stein, Miranda D. Stobbe, Ren X. Sun, Kevin Thai, Derek W. Wright, Chin-Lee Wu, Ke Yuan, Junjun Zhang
Feb 04, 2021
Abstract: In cancer, the primary tumour’s organ of origin and histopathology are the strongest determinants of its clinical behaviour, but in 3% of cases a patient presents with a metastatic tumour and no obvious primary....
10Kin1day
Martijn P van den Heuvel, Lianne H Scholtens, Hannelore K van der Burgh, Federica Agosta, Clara Alloza, Celso Arango, Bonnie Auyeung, Simon Baron-Cohen, Silvia Basaia, Manon JNL Benders, Frauke Beyer, Linda Booij, Kees PJ Braun, Geraldo Busatto Filho, Wiepke Cahn, Dara M Cannon, Tiffany M Chaim-Avancini, Sandra SM Chan, Eric YH Chen, Benedicto Crespo-Facorro, Eveline A Crone, Udo Dannlowski, Sonja MC de Zwarte, Bruno Dietsche, Gary Donohoe, Stefan Du Plessis, Sarah Durston, Covadonga M Díaz-Caneja, Ana M Díaz-Zuluaga, Robin Emsley, Massimo Filippi, Thomas Frodl, Martin Gorges, Beata Graff, Dominik Grotegerd, Dariusz Gąsecki, Julie M Hall, Laurena Holleran, Rosemary Holt, Helene J Hopman, Andreas Jansen, Joost Janssen, Krzysztof Jodzio, Lutz Jäncke, Vasiliy G Kaleda, Jan Kassubek, Shahrzad Kharabian Masouleh, Tilo Kircher, Martijn GJC Koevoets, Vladimir S Kostic, Axel Krug, Stephen M Lawrie, Irina S Lebedeva, Edwin HM Lee, Tristram A Lett, Simon JG Lewis, Franziskus Liem, Michael V Lombardo, Carlos Lopez-Jaramillo, Daniel S Margulies, Sebastian Markett, Paulo Marques, Ignacio Martínez-Zalacaín, Colm McDonald, Andrew M McIntosh, Genevieve McPhilemy, Susanne L Meinert, José M Menchón, Christian Montag, Pedro S Moreira, Pedro Morgado, David O Mothersill, Susan Mérillat, Hans-Peter Müller, Leila Nabulsi, Pablo Najt, Krzysztof Narkiewicz, Patrycja Naumczyk, Bob Oranje, Victor Ortiz-Garcia de la Foz, Jiska S Peper, Julian A Pineda, Paul E Rasser, Ronny Redlich, Jonathan Repple, Martin Reuter, Pedro GP Rosa, Amber NV Ruigrok, Agnieszka Sabisz, Ulrich Schall, Soraya Seedat, Mauricio H Serpa, Stavros Skouras, Carles Soriano-Mas, Nuno Sousa, Edyta Szurowska, Alexander S Tomyshev, Diana Tordesillas-Gutierrez, Sofie L Valk, Leonard H Van den Berg, Theo GM van Erp, Neeltje EM van Haren, Judith MC van Leeuwen, Arno Villringer, Christiaan H Vinkers, Christian Vollmar, Lea Waller, Henrik Walter, Heather C Whalley, Marta Witkowska, A Veronica Witte, Marcus V Zanetti, Rui Zhang, Siemon C de Lange
Jun 12, 2019
We organized 10Kin1day, a pop-up scientific event with the goal to bring together neuroimaging groups from around the world to jointly analyze 10,000+ existing MRI connectivity datasets during a 3-day workshop. In this report...