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Poly(2-oxazolines) in biological and biomedical application contexts.
Polyoxazolines of various architectures and chemical functionalities can be prepared in a living and therefore controlled manner via cationic ring-opening polymerisation. They have found widespread applications, ranging from...
Assessing the measurement invariance and antecedents of legal cynicism in São Paulo, Zurich, and Montevideo.
Amy Nivette, Nico Trajtenberg, Manuel Eisner, Denis Ribeaud, Maria Fernanda Tourinho Peres
Feb 19, 2021
INTRODUCTION: This paper accomplishes two goals. First, we assesses the measurement invariance of legal cynicism among adolescents in São Paulo, Brazil, Montevideo, Uruguay, and Zurich, Switzerland. Second, we evaluate a series...
Sensorimotor pathway controlling stopping behavior during chemotaxis in the Drosophila melanogaster larva.
Ibrahim Tastekin, Avinash Khandelwal, David Tadres, Nico D Fessner, James W Truman, Marta Zlatic, Albert Cardona, Matthieu Louis
Dec 19, 2018
Sensory navigation results from coordinated transitions between distinct behavioral programs. During chemotaxis in the Drosophila melanogaster larva, the detection of positive odor gradients extends runs while negative gradients...
Chemotaxis D. melanogaster behavioral quantification descending neuron motor control neuroscience olfaction sensorimotor transformation Animals Behavior Animal Biological Assay Chemotaxis Drosophila melanogaster Genetic Testing Larva Locomotion Motor Activity Motor Neurons olfactory receptor neurons optogenetics Peristalsis Phenotype Sensorimotor Cortex Smell
Brain responses to different types of salience in antipsychotic naïve first episode psychosis
Franziska Knolle, Anna O Ermakova, Azucena Justicia, Paul C Fletcher, Nico Bunzeck, Emrah Düzel, Graham K Murray
Oct 03, 2018
Abnormal salience processing has been suggested to contribute to the formation of positive psychotic symptoms in schizophrenia and related conditions. Previous research utilising reward learning or anticipation paradigms has...
The Grizzly, October 12, 2023
Marie Sykes, Michael Nieves-Hoblin, Nico Yanzaguano, Andrew J. Perez, Adam Denn, Dominic Minicozzi
Jan 01, 0001
Meet the New Professors on Campus Center for Career and Post-Graduate Events Professor Feature: Dr. Andy Davis Let's Do the (Rocky Horror: A Breakaway Student Production) Again The Captivating Collegeville Diner Crossword...
Ursinus College Collegeville Pennsylvania newspaper Career and Post-Graduate Development Andy Davis Breakaway Student Productions Collegeville Diner field hockey cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Targeting the Ubiquitin System in Glioblastoma
Glioblastoma is the most common primary brain tumor in adults with poor overall outcome and 5-year survival of less than 5%. Treatment has not changed much in the last decade or so, with surgical resection and radio/chemotherapy...
Targeting the Ubiquitin System in Glioblastoma
Glioblastoma is the most common primary brain tumor in adults with poor overall outcome and 5-year survival of less than 5%. Treatment has not changed much in the last decade or so, with surgical resection and radio/chemotherapy...
Multimodel inference for biomarker development
Jason D Cooper, Sung Yeon Sarah Han, Jakub Tomasik, Sureyya Ozcan, Nitin Rustogi, Nico JM van Beveren, F Markus Leweke, Sabine Bahn
May 01, 2019
In the present study, to improve the predictive performance of a model and its reproducibility when applied to an independent data set, we investigated the use of multimodel inference to predict the probability of having a...
Pretreatment levels of the fatty acid handling proteins H-FABP and CD36 predict response to olanzapine in recent-onset schizophrenia patients.
Jakub Tomasik, Emanuel Schwarz, Santiago G Lago, Matthias Rothermundt, F Markus Leweke, Nico JM van Beveren, Paul C Guest, Hassan Rahmoune, Johann Steiner, Sabine Bahn
Dec 04, 2015
biomarker CD36 FABP3 Olanzapine Personalised medicine Schizophrenia Adult Antipsychotic Agents Benzodiazepines CD36 Antigens Cohort Studies Fatty Acid Binding Protein 3 Fatty Acid-Binding Proteins Female Humans Interleukin-10 Male Middle Aged Olanzapine Quetiapine Fumarate Risperidone Schizophrenia Young Adult
An excitable Rho GTPase signaling network generates dynamic subcellular contraction patterns.
Melanie Graessl, Johannes Koch, Abram Calderon, Dominic Kamps, Soumya Banerjee, Tomáš Mazel, Nina Schulze, Jana Kathrin Jungkurth, Rutuja Patwardhan, Djamschid Solouk, Nico Hampe, Bernd Hoffmann, Leif Dehmelt, Perihan Nalbant
Nov 19, 2019
Rho GTPase-based signaling networks control cellular dynamics by coordinating protrusions and retractions in space and time. Here, we reveal a signaling network that generates pulses and propagating waves of cell contractions....
Using transfer learning from prior reference knowledge to improve the clustering of single-cell RNA-Seq data.
Bettina Mieth, James R F Hockley, Nico Görnitz, Marina M-C Vidovic, Klaus-Robert Müller, Alex Gutteridge, Daniel Ziemek
Feb 02, 2020
In many research areas scientists are interested in clustering objects within small datasets while making use of prior knowledge from large reference datasets. We propose a method to apply the machine learning concept of...
Published by: Scientific reports, volume 9, issue 1
Saccade dysmetria indicates attenuated visual exploration in autism spectrum disorder.
Nico Bast, Luke Mason, Christine M Freitag, Tim Smith, Ana Maria Portugal, Luise Poustka, Tobias Banaschewski, Mark Johnson, EU-AIMS LEAP group
Apr 12, 2021
BACKGROUND: Visual exploration in autism spectrum disorder (ASD) is characterized by attenuated social attention. The underlying oculomotor function during visual exploration is understudied, whereas oculomotor function during...
Obesity-Induced Metabolic Stress Leads to Biased Effector Memory CD4+ T Cell Differentiation via PI3K p110δ-Akt-Mediated Signals.
Claudio Mauro, Joanne Smith, Danilo Cucchi, David Coe, Hongmei Fu, Fabrizia Bonacina, Andrea Baragetti, Gaia Cermenati, Donatella Caruso, Nico Mitro, Alberico L Catapano, Enrico Ammirati, Maria P Longhi, Klaus Okkenhaug, Giuseppe D Norata, Federica M Marelli-Berg
Jun 27, 2018
Low-grade systemic inflammation associated to obesity leads to cardiovascular complications, caused partly by infiltration of adipose and vascular tissue by effector T cells. The signals leading to T cell differentiation and...
Akt CD4 T lymphocyte DIFFERENTIATION effector memory High-fat diet Inflammation obesity palmitate saturated fatty acid Adiposity Animals Antigen Presentation CD4-Positive T-Lymphocytes Cell Differentiation Cell Movement Dendritic Cells Diet High-Fat Fatty Acids Female Humans Immunologic Memory Inflammation Lymphocyte Activation Lymphoid Tissue Male Mice Inbred C57BL obesity Oxidation-Reduction Phenotype Phosphatidylinositol 3-Kinases Proto-Oncogene Proteins c-akt Receptors CXCR3 Signal Transduction Stress Physiological
Spontaneous organization of supracolloids into three-dimensional structured materials.
Mohammad-Amin Moradi, E Deniz Eren, Massimiliano Chiappini, Sebastian Rzadkiewicz, Maurits Goudzwaard, Mark MJ van Rijt, Arthur DA Keizer, Alexander F Routh, Marjolein Dijkstra, Gijsbertus de With, Nico Sommerdijk, Heiner Friedrich, Joseph P Patterson
Feb 15, 2021
Periodic nano- or microscale structures are used to control light, energy and mass transportation. Colloidal organization is the most versatile method used to control nano- and microscale order, and employs either the...
Dovetailing biology and chemistry
David P Hill, Nico Adams, Mike Bada, Colin Batchelor, Tanya Z Berardini, Heiko Dietze, Harold J Drabkin, Marcus Ennis, Rebecca E Foulger, Midori A Harris, Janna Hastings, Namrata S Kale, Paula de Matos, Christopher J Mungall, Gareth Owen, Paola Roncaglia, Christoph Steinbeck, Steve Turner, Jane Lomax
May 06, 2020
BACKGROUND: The Gene Ontology (GO) facilitates the description of the action of gene products in a biological context. Many GO terms refer to chemical entities that participate in biological processes. To facilitate accurate and...
Affect-Driven Learning of Robot Behaviour for Collaborative Human-Robot Interactions.
Collaborative interactions require social robots to share the users' perspective on the interactions and adapt to the dynamics of their affective behaviour. Yet, current approaches for affective behaviour generation in robots...
Two distinct β-sheet structures in Italian-mutant amyloid-beta fibrils
Ellen Hubin, Stéphanie Deroo, Gabriele Kaminksi Schierle, Clemens Kaminski, Louise Serpell, Vinod Subramaniam, Nico van Nuland, Kerensa Broersen, Vincent Raussens, Rabia Sarroukh
Feb 12, 2020
Most Alzheimer's disease (AD) cases are late-onset and characterized by the aggregation and deposition of the amyloid-beta (Aβ) peptide in extracellular plaques in the brain. However, a few rare and hereditary Aβ mutations, such...
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