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Perioperative management of patients with rheumatoid arthritis undergoing orthopaedic surgery.
Rheumatoid arthritis is an autoimmune disease which is characterised by systemic inflammation. In the recent decades, the advent of disease modifying anti-rheumatic drugs have reduced the need for orthopaedic procedures....
Understanding cost-utility analysis studies in the trauma and orthopaedic surgery literature.
Cost-utility analysis (CUA) studies are becoming increasingly important due to the need to reduce healthcare spending, especially in the field of trauma and orthopaedics.There is an increasing need for trauma and orthopaedic...
Meta-Analysis of Adipose Tissue Derived Cell-Based Therapy for the Treatment of Knee Osteoarthritis
Osteoarthritis (OA) is a degenerative disorder associated with cartilage loss and is a leading cause of disability around the world. In old age, the capacity of cartilage to regenerate is diminished. With an aging population...
Meta-Analysis of Adipose Tissue Derived Cell-Based Therapy for the Treatment of Knee Osteoarthritis.
Osteoarthritis (OA) is a degenerative disorder associated with cartilage loss and is a leading cause of disability around the world. In old age, the capacity of cartilage to regenerate is diminished. With an aging population...
Affect-Driven Learning of Robot Behaviour for Collaborative Human-Robot Interactions.
Collaborative interactions require social robots to share the users' perspective on the interactions and adapt to the dynamics of their affective behaviour. Yet, current approaches for affective behaviour generation in robots...
Biosensors for screening kinase inhibitors
For successful drug discovery it is important to understand the fundamentals of the underlying causes and consequences of the diseases for which the drug is being developed. One such physiological process in eukaryotic cells is...
An experimental investigation to model wheezing in lungs.
A quarter of the world's population experience wheezing. These sounds have been used for diagnosis since the time of the Ebers Papyrus (ca 1500 BC). We know that wheezing is a result of the oscillations of the airways...
The shaken realist
Abstract: Bernard Williams thought that philosophy should address real human concerns felt beyond academic philosophy. But what wider concerns are addressed by Ethics and the Limits of Philosophy, a book he introduces as being...
Exploiting the signatures of nanoplasmon-exciton coupling on proton sensitive insulator-semiconductor devices for drug discovery applications
Multimodal sensing methods have a great promise in biosensing applications as they can measure independently several properties that characterise the biomolecular interaction to be detected as well as providing inherent on-chip...
Introduction to biosensors
Biosensors are nowadays ubiquitous in biomedical diagnosis as well as a wide range of other areas such as point-of-care monitoring of treatment and disease progression, environmental monitoring, food control, drug discovery...
Semiconductor technology in protein kinase research and drug discovery
Since the discovery of protein kinase activity in 1954, close to 600 kinases have been discovered that have crucial roles in cell physiology. In several pathological conditions, aberrant protein kinase activity leads to abnormal...
Protein phosphorylation analysis based on proton release detection
Phosphorylation is the most important post-translational modification of proteins in eukaryotic cells and it is catalysed by enzymes called kinases. The balance between protein phosphorylation and dephosphorylation is critical...
Dominant hemisphere functional networks compensate for structural connectivity loss to preserve phonological retrieval with aging.
INTRODUCTION: Loss of hemispheric asymmetry during cognitive tasks has been previously demonstrated in the literature. In the context of language, increased right hemisphere activation is observed with aging. Whether this...
Coping with personhood limbo
Prevailing socio-legal structures create a state of personhood limbo for undocumented workers, where broader society undermines various aspects of their personhood in a way that prevents them from fully representing and...
Protein phosphorylation detection using dual-mode field-effect devices and nanoplasmonic sensors
Phosphorylation by kinases is an important post-translational modification of proteins. It is a critical control for the regulation of vital cellular activities, and its dysregulation is implicated in several diseases. A common...
Protein phosphorylation detection using dual-mode field-effect devices and nanoplasmonic sensors
Phosphorylation by kinases is an important post-translational modification of proteins. It is a critical control for the regulation of vital cellular activities, and its dysregulation is implicated in several diseases. A common...
Introduction to biosensors
Biosensors are nowadays ubiquitous in biomedical diagnosis as well as a wide range of other areas such as point-of-care monitoring of treatment and disease progression, environmental monitoring, food control, drug discovery...
Exploiting the signatures of nanoplasmon-exciton coupling on proton sensitive insulator-semiconductor devices for drug discovery applications
Multimodal sensing methods have a great promise in biosensing applications as they can measure independently several properties that characterise the biomolecular interaction to be detected as well as providing inherent on-chip...
Coping with personhood limbo
Prevailing socio-legal structures create a state of personhood limbo for undocumented workers, where broader society undermines various aspects of their personhood in a way that prevents them from fully representing and...
Ordering Policy Estimation for High Utility Item-Sets Considering Negative Item Values in Large Databases
Reshu Agarwal
Jan 01, 2022
Utility mining with negative item values has recently received interest in the data mining field due to its practical considerations. Previously, the values of utility item-sets have been taken into consideration as positive....
A simple non-parametric method for resolving merged doublet lines

Doublet line emission and absorption are common in astronomical sources (e.g. [OIII], [O II], NaD, MgII). In many cases, complex kinematics in the emitting source can cause the doublet lines to merge, making characterization...

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