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A Systematic Review of Neurosurgical Care in Low-Income Countries.
Hannah K Weiss, Roxanna M Garcia, Jesutofunmi A Omiye, Dominique Vervoort, Robert Riestenberg, Ketan Yerneni, Nikhil Murthy, Annie B Wescott, Peter Hutchinson, Gail Rosseau
Feb 19, 2020
Objective:More than 5 billion individuals lack access to essential surgical care. Neurosurgical care is especially limited in low-income countries (LICs). Studies describing neurosurgical care in LICs are critical for...
Research Traumatic brain injury Hydrocephalus Literature review Global Health Low-income Countries TBI Traumatic Brain Injury Global neurosurgery Lcogs Lancet Commission On Global Surgery Lic Low-income Country
Published by: World neurosurgery: X
A Systematic Review of Neurosurgical Care in Low-Income Countries.
Hannah K Weiss, Roxanna M Garcia, Jesutofunmi A Omiye, Dominique Vervoort, Robert Riestenberg, Ketan Yerneni, Nikhil Murthy, Annie B Wescott, Peter Hutchinson, Gail Rosseau
Feb 24, 2020
OBJECTIVE: More than 5 billion individuals lack access to essential surgical care. Neurosurgical care is especially limited in low-income countries (LICs). Studies describing neurosurgical care in LICs are critical for...
Affect-Driven Learning of Robot Behaviour for Collaborative Human-Robot Interactions.
Collaborative interactions require social robots to share the users' perspective on the interactions and adapt to the dynamics of their affective behaviour. Yet, current approaches for affective behaviour generation in robots...
Impact of HR Practices on Organizational Effectiveness
The purpose of this paper is to identify the factors for both HR practices and organizational effectiveness along with what extent HR practices impact organizational effectiveness. The data were randomly collected from faculty...
Published by: IGI Global Scientific Publishing
Modified HEK cells simulate DCT cells in their sensitivity and response to changes in extracellular K.
A potassium (K+ ) rich diet is known to have an antihypertensive effect that has been embodied by the NHLBI in the DASH diet. However, the molecular basis for this blood pressure-lowering effect has been unclear, until a recent...
Biosensors for screening kinase inhibitors
For successful drug discovery it is important to understand the fundamentals of the underlying causes and consequences of the diseases for which the drug is being developed. One such physiological process in eukaryotic cells is...
Selective digestive decontamination in critically ill children
Background
Selective digestive decontamination of the digestive tract involves the routine administration of oral, gastric, and intravenous antibiotics to mechanically ventilated children to prevent hospital-acquired...
Modified HEK cells simulate DCT cells in their sensitivity and response to changes in extracellular K.
The shaken realist
Abstract: Bernard Williams thought that philosophy should address real human concerns felt beyond academic philosophy. But what wider concerns are addressed by Ethics and the Limits of Philosophy, a book he introduces as being...
Exploiting the signatures of nanoplasmon-exciton coupling on proton sensitive insulator-semiconductor devices for drug discovery applications
Multimodal sensing methods have a great promise in biosensing applications as they can measure independently several properties that characterise the biomolecular interaction to be detected as well as providing inherent on-chip...
Introduction to biosensors
Biosensors are nowadays ubiquitous in biomedical diagnosis as well as a wide range of other areas such as point-of-care monitoring of treatment and disease progression, environmental monitoring, food control, drug discovery...
Semiconductor technology in protein kinase research and drug discovery
Since the discovery of protein kinase activity in 1954, close to 600 kinases have been discovered that have crucial roles in cell physiology. In several pathological conditions, aberrant protein kinase activity leads to abnormal...
WNK signalling pathways in blood pressure regulation.
hyperkalemia Hypertension NCC Proteasome SPAK/OSR1 phosphorylation Ubiquitin-E3 ligase complex WNK kinases Animals blood pressure Cullin Proteins Humans Hypertension Neovascularization Physiologic Protein Serine-Threonine Kinases Pseudohypoaldosteronism Receptors Drug Signal Transduction Sodium Chloride Symporters Sodium-Potassium-Chloride Symporters
Protein phosphorylation analysis based on proton release detection
Phosphorylation is the most important post-translational modification of proteins in eukaryotic cells and it is catalysed by enzymes called kinases. The balance between protein phosphorylation and dephosphorylation is critical...
Protein phosphorylation detection using dual-mode field-effect devices and nanoplasmonic sensors
Phosphorylation by kinases is an important post-translational modification of proteins. It is a critical control for the regulation of vital cellular activities, and its dysregulation is implicated in several diseases. A common...
Protein phosphorylation detection using dual-mode field-effect devices and nanoplasmonic sensors
Phosphorylation by kinases is an important post-translational modification of proteins. It is a critical control for the regulation of vital cellular activities, and its dysregulation is implicated in several diseases. A common...
ROMK expression remains unaltered in a mouse model of familial hyperkalemic hypertension caused by the CUL3Δ403-459 mutation.
Cullin‐3 ROMK WNK kinases hyperkalemia Proteasome ubiquitin‐ligase complex Adaptor Proteins Signal Transducing Animals Biomarkers Cell Line Cullin Proteins Gene Knock-In Techniques Genetic Predisposition to Disease Kidney Membrane Potentials Mice Transgenic Microfilament Proteins Mutation Oocytes Phenotype Potassium Potassium Channels Inwardly Rectifying Protein Processing Post-Translational Protein Serine-Threonine Kinases Pseudohypoaldosteronism Transfection Xenopus laevis
Immune reconstitution after alemtuzumab therapy for multiple sclerosis triggering Graves' orbitopathy
Jonathan CP Roos, Carla Moran, V Krishna Chatterjee, Joanne Jones, Alasdair Coles, Rachna Murthy
Dec 20, 2018
Alemtuzumab-a monoclonal antibody targeting the CD52 glycoprotein expressed by most mature leucocytes-effectively decreases relapse rate and disability progression in early, relapsing-remitting multiple sclerosis (MS). However...
Adolescent Adult Alemtuzumab Antineoplastic Agents Immunological Autoantibodies Disease Progression Enzyme-Linked Immunosorbent Assay Female Graves Ophthalmopathy Humans Immune Reconstitution Magnetic Resonance Imaging Male Middle Aged Multiple Sclerosis Receptors Thyrotropin Recurrence Retrospective Studies Risk Factors
Introduction to biosensors
Biosensors are nowadays ubiquitous in biomedical diagnosis as well as a wide range of other areas such as point-of-care monitoring of treatment and disease progression, environmental monitoring, food control, drug discovery...
Exploiting the signatures of nanoplasmon-exciton coupling on proton sensitive insulator-semiconductor devices for drug discovery applications
Multimodal sensing methods have a great promise in biosensing applications as they can measure independently several properties that characterise the biomolecular interaction to be detected as well as providing inherent on-chip...
A simple non-parametric method for resolving merged doublet lines
Doublet line emission and absorption are common in astronomical sources (e.g. [OIII], [O II], NaD, MgII). In many cases, complex kinematics in the emitting source can cause the doublet lines to merge, making characterization...
Understanding cost-utility analysis studies in the trauma and orthopaedic surgery literature.
Cost-utility analysis (CUA) studies are becoming increasingly important due to the need to reduce healthcare spending, especially in the field of trauma and orthopaedics.There is an increasing need for trauma and orthopaedic...
T2-relaxation mapping and fat fraction assessment to objectively quantify clinical activity in thyroid eye disease
Imaging in thyroid eye disease (TED) is used to exclude other diagnoses, assess for apical crowding and plan surgery. But to quantify TED activity objectively, subjective clinical scoring assessments remain the norm. Magnetic...
Biosensors for screening kinase inhibitors
For successful drug discovery it is important to understand the fundamentals of the underlying causes and consequences of the diseases for which the drug is being developed. One such physiological process in eukaryotic cells is...
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