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Inferring exemplar discriminability in brain representations.
Representational distinctions within categories are important in all perceptual modalities and also in cognitive and motor representations. Recent pattern-information studies of brain activity have used condition-rich designs to...
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A small number of anti-CD3 molecules on dendritic cells stimulates DNA synthesis in mouse T lymphocytes
Romani, N., Inaba, K., Puré, E., Crowley, M., Witmer-Pack, M., and Steinman, R.M. A small number of anti-CD3 molecules on dendritic cells stimulates DNA synthesis in mouse T lymphocytes. J. Exp. Med. 169: 1153-1168, 1989
Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte-macrophage colony stimulating factor
Inaba, K., Inaba, M., Romani, N., Aya, H., Deguchi, M., Ikehara, S., Muramatsu, S., and Steinman, R.M. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte-macrophage...
Presentation of exogenous protein antigens by dendritic cells to T cell clones. Intact protein is presented best by immature, epidermal Langerhans cells
The capacity of dendritic cells to present protein antigens has been studied with two MHC class II-restricted, myoglobin-specific, T cell clones. Spleen dendritic cells and cultured epidermal Langerhans cells (LC) presented...
Published by: Rockefeller University
Presentation of exogenous protein antigens by dendritic cells to T cell clones: intact protein is presented best by immature, epidermal Langerhans cells
Romani, N., Koide, S., Crowley, M., Witmer-Pack, M., Livingston, A.M., Fathman, C.G., Inaba, K., and Steinman, R.M. Presentation of exogenous protein antigens by dendritic cells to T cell clones: intact protein is presented best...
A comparison of murine epidermal Langerhans cells with spleen dendritic cells
To establish if epidermal Langerhans cells (LC) are related to spleen dendritic cells, we have considered the morphology, phenotype, and function of the 2 cell types in culture. Cultured LC could be partially enriched (up to...
Published by: Rockefeller University
Recurrent Convolutional Neural Networks
Feedforward neural networks provide the dominant model of how the brain performs visual object recognition. However, these networks lack the lateral and feedback connections, and the resulting recurrent neuronal dynamics, of the...
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Proliferating dendritic cell progenitors in human blood
CD34+cells in human cord blood and marrow are known to give rise to dendritic cells (DC), as well as to other myeloid lineages. CD34+cells are rare in adult blood, however, making it difficult to use CD34 + ceils to ascertain if...
Published by: Rockefeller University
An antigen-independent contact mechanism as an early step in T cell-proliferative responses to dendritic cells
Dendritic cells bearing antigen efficiently aggregate and stimulate antigen-specific T cells. We describe an experimental model in which an initial, apparently antigen-independent binding step is followed by ligation of the TCR....
Published by: Rockefeller University
Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor
Antigen-presenting, major histocompatibility complex (MHC) class II-rich dendritic cells are known to arise from bone marrow. However, marrow lacks mature dendritic cells, and substantial numbers of proliferating less-mature...
Published by: Rockefeller University
A small number of anti-CD3 molecules on dendritic cells stimulate DNA synthesis in mouse T lymphocytes
Resting T cells enter cell cycle when challenged with anti-CD3 mAb and accessory cells that bear required Fc receptor (FcR). Presentation of anti-CD3 is though to be a model for antigens presented by accessory cells to the TCR...
Published by: Rockefeller University
Proliferating dendritic cell progenitors in human blood
Romani, N., Gruner, S., Brang, D., Kampgen, E., Lenz, A., Trockenbacher, B., Konwalinka, G., Fritsch, P.O., Steinman, R.M., and Schuler, G. Proliferating dendritic cell progenitors in human blood. J. Exp. Med. 180:83-93, 1994
Clinical Validation of an Automated Fluorogenic Factor XIII Activity Assay Based on Isopeptidase Activity.
Hereditary factor XIII (FXIII) deficiency is a rare autosomal bleeding disorder which can cause life-threatening bleeding. Acquired deficiency can be immune-mediated or due to increased consumption or reduced synthesis. The most...
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A toolbox for representational similarity analysis.
Neuronal population codes are increasingly being investigated with multivariate pattern-information analyses. A key challenge is to use measured brain-activity patterns to test computational models of brain information...
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Recurrent neural networks can explain flexible trading of speed and accuracy in biological vision.
Deep feedforward neural network models of vision dominate in both computational neuroscience and engineering. The primate visual system, by contrast, contains abundant recurrent connections. Recurrent signal flow enables...
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Individual differences among deep neural network models.
Deep neural networks (DNNs) excel at visual recognition tasks and are increasingly used as a modeling framework for neural computations in the primate brain. Just like individual brains, each DNN has a unique connectivity and...
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