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Influenza virus-infected dendritic cells stimulate strong proliferative and cytolytic responses from human CD8+ T cells
Bhardwaj, N., Bender, A., Gonzalez, N., Bui, L.K., Garrett, M.C., and Steinman, R.M. Influenza virus-infected dendritic cells stimulate strong proliferative and cytolytic responses from human CD8+ T cells. J. Clin. Invest. 94...
Published by: The American Society for Clinical Investigation
Influenza virus-infected dendritic cells stimulate strong proliferative and cytolytic responses from human CD8+ T cells
Antigen-specific, CD8+, cytolytic T lymphocytes (CTLs) could potentially provide resistance to several infectious and malignant diseases. However, the cellular requirements for the generation of specific CTLs in human lymphocyte...
Published by: Rockefeller University
Sign-Inverting Vectors Underlie a Coordinate Transformation in the Drosophila Central Brain
Itzel Gonzalez Ishida
Jan 01, 0001
Our coherent sense of orientation is built from combining sensory experiences across different modalities. How animal brains compute and remember the directions of motion of the body, limbs, objects or landmarks in a shared...
Published by: Rockefeller University
Insoluble tau aggregates induce neuronal death through modification of membrane ion conductance, activation of voltage-gated calcium channels and NADPH oxidase.
Noemi Esteras, Franziska Kundel, Giuseppe F Amodeo, Evgeny V Pavlov, David Klenerman, Andrey Y Abramov
May 11, 2020
BLM NADPH oxidase insoluble tau nifedipine voltage-gated calcium channels Amyloid beta-Peptides Animals Animals Newborn Astrocytes Calcium Calcium Channels Cell Death Coculture Techniques Gene Expression Regulation Humans NADPH Oxidases Neurons Nifedipine Oxidation-Reduction Primary Cell Culture Protein Aggregates Rats Rats Sprague-Dawley Reactive Oxygen Species Thapsigargin Verapamil tau Proteins
Decision-to-delivery interval of emergency cesarean section in Uganda
Noemi J Hughes, Imelda Namagembe, Annettee Nakimuli, Musa Sekikubo, Ashley Moffett, Charlotte J Patient, Catherine E Aiken
May 13, 2020
Catching the Sugars
Ana Diaz-Fernandez, Rebeca Miranda-Castro, Pedro Estrela, Noemi de los Santos Alvarez, Maria Jesus Lobo Castanon
Nov 02, 2020
Prostate-specific Antigen (PSA) is the biomarker that is used for prostate cancer (PCa) detection, although its lack of specificity results in a high rate of false-positives and many unnecessary biopsies. Therefore, there is a...
Aptamer-based Glycan PSA Score for Discrimination of Prostate Cancer from other Prostate Diseases
Ana Diaz-Fernandez, Rebeca Miranda-Castro, Noemi de los Santos Alvarez, Maria Jesus Lobo Castanon, Pedro Estrela
Mar 01, 2021
Prostate specific antigen (PSA) is the common biomarker for prostate cancer (PCa). However, its lack of specificity to differentiate PCa from benign prostate disorders stimulates the search for alternative cancer biomarkers to...
Catching the Sugars
Ana Diaz-Fernandez, Rebeca Miranda-Castro, Pedro Estrela, Noemi de los Santos Alvarez, Maria Jesus Lobo Castanon
Nov 02, 2020
Prostate-specific Antigen (PSA) is the biomarker that is used for prostate cancer (PCa) detection, although its lack of specificity results in a high rate of false-positives and many unnecessary biopsies. Therefore, there is a...
Sex-specific associations of basal steroid hormones and neuropeptides with Conduct Disorder and neuroendocrine mediation of environmental risk
Anka Bernhard, Marietta Kirchner, Anne Martinelli, Katharina Ackermann, Gregor Kohls, Karen Gonzalez-Madruga, Amy Wells, Aranzazu Fernández-Rivas, Maider Gonzalez De Artaza-Lavesa, Nora Maria Raschle, Angeliki Konsta, Réka Siklósi, Amaia Hervás, Beate Herpertz-Dahlmann, Stephane A. De Brito, Arne Popma, Christina Stadler, Kerstin Konrad, Graeme Fairchild, Christine M. Freitag
Aug 31, 2021
Conduct Disorder (CD) is characterized by severe aggressive and antisocial behavior. The stress hormone system has frequently been investigated as a neurobiological correlate of CD, while other interacting neuroendocrine...
Conduct Disorder Environmental risk factors FEMNAT-CD Neuropeptides Sex differences Steroid hormones /dk/atira/pure/subjectarea/asjc/3000/3004 name=Pharmacology /dk/atira/pure/subjectarea/asjc/2800/2808 name=Neurology /dk/atira/pure/subjectarea/asjc/2700/2728 name=Clinical Neurology /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/subjectarea/asjc/2800/2803 name=Biological Psychiatry /dk/atira/pure/subjectarea/asjc/2700/2736 name=Pharmacology (medical) /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Aptamer-based Glycan PSA Score for Discrimination of Prostate Cancer from other Prostate Diseases
Ana Diaz-Fernandez, Rebeca Miranda-Castro, Noemi de los Santos Alvarez, Maria Jesus Lobo Castanon, Pedro Estrela
Mar 01, 2021
Prostate specific antigen (PSA) is the common biomarker for prostate cancer (PCa). However, its lack of specificity to differentiate PCa from benign prostate disorders stimulates the search for alternative cancer biomarkers to...
Sex-specific associations of basal steroid hormones and neuropeptides with Conduct Disorder and neuroendocrine mediation of environmental risk
Anka Bernhard, Marietta Kirchner, Anne Martinelli, Katharina Ackermann, Gregor Kohls, Karen Gonzalez-Madruga, Amy Wells, Aranzazu Fernández-Rivas, Maider Gonzalez De Artaza-Lavesa, Nora Maria Raschle, Angeliki Konsta, Réka Siklósi, Amaia Hervás, Beate Herpertz-Dahlmann, Stephane A. De Brito, Arne Popma, Christina Stadler, Kerstin Konrad, Graeme Fairchild, Christine M. Freitag
Aug 31, 2021
Conduct Disorder (CD) is characterized by severe aggressive and antisocial behavior. The stress hormone system has frequently been investigated as a neurobiological correlate of CD, while other interacting neuroendocrine...
Conduct Disorder Environmental risk factors FEMNAT-CD Neuropeptides Sex differences Steroid hormones /dk/atira/pure/subjectarea/asjc/3000/3004 name=Pharmacology /dk/atira/pure/subjectarea/asjc/2800/2808 name=Neurology /dk/atira/pure/subjectarea/asjc/2700/2728 name=Clinical Neurology /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/subjectarea/asjc/2800/2803 name=Biological Psychiatry /dk/atira/pure/subjectarea/asjc/2700/2736 name=Pharmacology (medical) /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Genome-Scale Metabolic Model Driven Design of a Defined Medium for Campylobacter jejuni M1cam.
Noemi Tejera, Lisa Crossman, Bruce Pearson, Emily Stoakes, Fauzy Nasher, Bilal Djeghout, Mark Poolman, John Wain, Dipali Singh
Jul 03, 2020
Campylobacter jejuni, the most frequent cause of food-borne bacterial gastroenteritis, is a fastidious organism when grown in the laboratory. Oxygen is required for growth, despite the presence of the metabolic mechanism for...
Facial geometry parameterisation based on Partial Differential Equations
Geometric modelling using Partial Differential Equations (PDEs) has been gradually recognised due to its smooth instinct, as well as the ability to generate a variety of geometric shapes by intuitively manipulating a relatively...
Decision-to-delivery interval of emergency cesarean section in Uganda
Noemi J. Hughes, Imelda Namagembe, Annettee Nakimuli, Musa Sekikubo, Ashley Moffett, Charlotte J. Patient, Catherine E. Aiken
May 27, 2021
HaloFlippers
Karolína Straková, Javier López-Andarias, Noemi Jiménez-Rojo, Joseph E Chambers, Stefan J Marciniak, Howard Riezman, Naomi Sakai, Stefan Matile
Oct 21, 2020
Tools to image membrane tension in response to mechanical stimuli are badly needed in mechanobiology. We have recently introduced mechanosensitive flipper probes to report quantitatively global membrane tension changes in...
Decision-to-delivery interval of emergency cesarean section in Uganda
Noemi J. Hughes, Imelda Namagembe, Annettee Nakimuli, Musa Sekikubo, Ashley Moffett, Charlotte J. Patient, Catherine E. Aiken
Jun 06, 2020
Facial geometry parameterisation based on Partial Differential Equations
Geometric modelling using Partial Differential Equations (PDEs) has been gradually recognised due to its smooth instinct, as well as the ability to generate a variety of geometric shapes by intuitively manipulating a relatively...
A soil microbial fuel cell-based biosensor for dissolved oxygen monitoring in water
Water pollution can cause significant depletions of dissolved oxygen (DO) in water systems with serious environmental and economic consequences. Online and continuous monitoring of DO can help prevent or minimise the risks...
A soil microbial fuel cell-based biosensor for dissolved oxygen monitoring in water
Water pollution can cause significant depletions of dissolved oxygen (DO) in water systems with serious environmental and economic consequences. Online and continuous monitoring of DO can help prevent or minimise the risks...
Symposium overview:
Javier T. Gonzalez
Jul 15, 2019
Substrate Utilisation and Energy Metabolism in Non-Growing Campylobacter jejuni M1cam.
Emily Stoakes, George M Savva, Ruby Coates, Noemi Tejera, Mark G Poolman, Andrew J Grant, John Wain, Dipali Singh
Sep 02, 2022
Campylobacter jejuni, the major cause of bacterial foodborne illness, is also a fastidious organism that requires strict growth requirements in the laboratory. Our aim was to study substrate utilisation and energy metabolism in...
Measurement of Tau Filament Fragmentation Provides Insights into Prion-like Spreading.
Franziska Kundel, Liu Hong, Benjamin Falcon, William A McEwan, Thomas CT Michaels, Georg Meisl, Noemi Esteras, Andrey Y Abramov, Tuomas JP Knowles, Michel Goedert, David Klenerman
Jul 13, 2018
The ordered assembly of amyloidogenic proteins causes a wide spectrum of common neurodegenerative diseases, including Alzheimer's and Parkinson's diseases. These diseases share common features with prion diseases, in which...
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