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When Emotions Rule Knowledge
Although emotions play an important role in human behavior and knowledge studies, knowledge management (KM) research considers them from specific angles and, to date, has lacked a comprehensive understanding of the emotions...
Published by: IGI Global Scientific Publishing
The Ursinus Weekly, October 8, 1970
Alan Gold, Bob Swarr, Candy Silver, Marc Hauser, Charles Chambers, Cris Crane, Peter von Sothen
Jan 01, 0001
Pettit inauguration scheduled; Appointments still undetermined Ursinus institutes security measures to protect students Obituaries: Dr. Paul R. Wagner; Nora Shuler Helfferich Ashley Montagu appears in first Forum program ...
Ursinus College Collegeville Pennsylvania newspaper William Schuyler Pettit Donald L. Helfferich security Miley Detective Agency identification cards Paul R. Wagner Nora Shuler Helfferich Ashley Montagu Art Severance field hockey Football cross country Bruce Albert cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer.
Zhi Hu, Jian-Hua Mao, Christina Curtis, Ge Huang, Shenda Gu, Laura Heiser, Marc E Lenburg, James E Korkola, Nora Bayani, Shamith Samarajiwa, Jose A Seoane, Mark A Dane, Amanda Esch, Heidi S Feiler, Nicholas J Wang, Mary Ann Hardwicke, Sylvie Laquerre, Jeff Jackson, Kenneth W Wood, Barbara Weber, Paul T Spellman, Samuel Aparicio, Richard Wooster, Carlos Caldas, Joe W Gray
Oct 18, 2018
BACKGROUND: High mitotic activity is associated with the genesis and progression of many cancers. Small molecule inhibitors of mitotic apparatus proteins are now being developed and evaluated clinically as anticancer agents....
Breast Cancer Mitotic Index Novel therapeutics Predictive biomarker Aurora Kinases Breast Neoplasms Cell Cycle Proteins Cell Line Tumor Cell Proliferation Chromosomal Proteins Non-Histone Female Gene Amplification Gene Expression Profiling Gene Expression Regulation Neoplastic Gene Regulatory Networks Genome Human Humans Kaplan-Meier Estimate Mitosis Prognosis Protein Serine-Threonine Kinases Proto-Oncogene Proteins RNA Interference Small Molecule Libraries Treatment Outcome
Identification of a Microrna Network that Regulates Melanoma Metastasis and Angiogenesis by Targeting Apoe
Nora Pencheva
Jan 01, 0001
Metastatic melanoma, a prevalent and deadly form of skin cancer, remains an aggressive clinical outcome that lacks effective preventative and/or curative therapeutics. Patients diagnosed with advanced metastatic melanoma face a...
Published by: Rockefeller University
A Statistical-Mechanical Model for the Binding of Flexible Ligands to Proteins
Nora Dawn Laiken
Jan 01, 0001
In this dissertation, a theoretical model is presented for the binding of flexible ligands to proteins. The model explicitly accounts for the ability of these chain-like molecules to bind in a large number of configurations...
Published by: Rockefeller University
Development and validation of risk score for predicting positive repeat prostate biopsy in patients with a previous negative biopsy in a UK population.
Giant pyroelectric energy harvesting and a negative electrocaloric effect in multilayered nanostructures
This work examines the potential of PbZr0.53Ti0.47O3/CoFe2O4 (PZT/CFO) multi-layered nanostructures (MLNs) to achieve a giant electrocaloric effect (ECE) and enhanced...
Galaxy shape statistics in the effective field theory
Abstract: Intrinsic galaxy alignments yield an important contribution to the observed statistics of galaxy shapes. The general bias expansion for galaxy sizes and shapes in three dimensions has been recently described by Vlah...
Computational approaches to support comparative analysis of multiparametric tests
John MS Bartlett, Jane Bayani, Elizabeth N Kornaga, Patrick Danaher, Cheryl Crozier, Tammy Piper, Cindy Q Yao, Janet A Dunn, Paul C Boutros, Robert C Stein, OPTIMA Trial Management Group
Nov 09, 2020
Multiparametric assays for risk stratification are widely used in the management of breast cancer, with applications being developed for a number of other cancer settings. Recent data from multiple sources suggests that...
Galaxy shape statistics in the effective field theory
Abstract: Intrinsic galaxy alignments yield an important contribution to the observed statistics of galaxy shapes. The general bias expansion for galaxy sizes and shapes in three dimensions has been recently described by Vlah...
Cost-effectiveness of primary offer of IVF vs. primary offer of IUI followed by IVF (for IUI failures) in couples with unexplained or mild male factor subfertility.
Pyroelectric control of magnetization for tuning thermomagnetic energy conversion and magnetocaloric effect
Tri-layered PbZr0.53Ti0.47O3/CoFe2O4/PbZr0.53Ti0.47O3 (PZT/CFO/PZT) nanostructures have been reported to have the highest pyroelectric...
Reducing global health inequalities for a rare disorder
Tanzil Rujeedawa, Nora McNairney, Shelly Cordner, James O'Brien, Georgina Loughnan, Anthony Holland
Nov 21, 2022
BACKGROUND: People with rare disorders face significant global health inequalities; the challenge is how to raise awareness and develop a nucleus of experts in a country who are then able to provide guidance to others in that...
Dicer1 is required for pigment cell and craniofacial development in zebrafish
Andrea Weiner, Nadia Scampoli, Tomas Steeman, C. M. Dooley, Elisabeth Busch-Nentwich, Robert N. Kelsh, Nora Calcaterra
Apr 30, 2019
The multidomain RNase III endoribonuclease DICER is required for the generation of most functional microRNAs (miRNAs). Loss of Dicer affects developmental processes at different levels. Here, we characterized the zebrafish...
Neural Crest Zebrafish miRNAs Sox10 /dk/atira/pure/subjectarea/asjc/1300/1304 name=Biophysics /dk/atira/pure/subjectarea/asjc/1300/1315 name=Structural Biology /dk/atira/pure/subjectarea/asjc/1300/1303 name=Biochemistry /dk/atira/pure/subjectarea/asjc/1300/1312 name=Molecular Biology /dk/atira/pure/subjectarea/asjc/1300/1311 name=Genetics
Cost-effectiveness and Benefit-to-Harm Ratio of Risk-Stratified Screening for Breast Cancer
IMPORTANCE: The age-based or "one-size-fits-all" breast screening approach does not take into account the individual variation in risk. Mammography screening reduces death from breast cancer at the cost of overdiagnosis....
Polygenic risk-tailored screening for prostate cancer
Tom Callender, Mark Emberton, Steve Morris, Ros Eeles, Ros Eeles, Zsofia Kote-Jarai, Paul D P Pharoah, Nora Pashayan
Jan 27, 2020
BACKGROUND:The United States Preventive Services Task Force supports individualised decision-making for prostate-specific antigen (PSA)-based screening in men aged 55-69. Knowing how the potential benefits and harms of screening...
Giant pyroelectric energy harvesting and a negative electrocaloric effect in multilayered nanostructures
This work examines the potential of PbZr0.53Ti0.47O3/CoFe2O4 (PZT/CFO) multi-layered nanostructures (MLNs) to achieve a giant electrocaloric effect (ECE) and enhanced...
Pyroelectric control of magnetization for tuning thermomagnetic energy conversion and magnetocaloric effect
Tri-layered PbZr0.53Ti0.47O3/CoFe2O4/PbZr0.53Ti0.47O3 (PZT/CFO/PZT) nanostructures have been reported to have the highest pyroelectric...
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