The modeling of Alzheimer's disease by the overexpression of mutant Presenilin 1 in human embryonic stem cells.
Makoto Honda,
Itsunari Minami,
Norie Tooi,
Nobuhiro Morone,
Hisae Nishioka,
Kengo Uemura,
Ayae Kinoshita,
John E Heuser,
Norio Nakatsuji,
Kazuhiro Aiba
May 28, 2019
Cellular disease models are useful tools for Alzheimer's disease (AD) research. Pluripotent stem cells, including human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs), are promising materials for...