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Change Management Perceptions in Portuguese Hospital Institutions Through ITIL
Organizations function in complex, dynamic and unpredictable environments. Implementing changes must therefore be well planned, managed, and evaluated as such ongoing efforts link organizational performance to peer...
Published by: IGI Global Scientific Publishing
Vocal Acoustic Analysis
Vocal acoustic analysis is becoming a useful tool for the classification and recognition of laryngological pathologies. This technique enables a non-invasive and low-cost assessment of voice disorders, allowing a more efficient...
Published by: IGI Global Scientific Publishing
Volatility Transmission Between ASEAN-5 Stock Exchanges
This article aims to analyse risk transmission among the financial markets of China and ASEAN-5 in the context of the 2015 Chinese stock market crash. For this purpose, the authors test if (1) the volatility resulting from the...
Published by: IGI Global Scientific Publishing
Technical-Economic Feasibility Study of a Tri-Generation System in an Isolated Tropical Island
Over the years, and despite the energy efficiency measures and possibilities, there has been an increase in energy consumption worldwide. However, the resources and primary energies are limited and short stocked, and the energy...
Published by: IGI Global Scientific Publishing
Stimulation of cell invasion by the Golgi Ion Channel GAAP/TMBIM4 via an H2O2-Dependent Mechanism.
Nuno Almeida, Guia Carrara, Carlos M Palmeira, Ana S Fernandes, Maddy Parsons, Geoffrey L Smith, Nuno Saraiva
Oct 29, 2019
The mechanisms by which the Golgi apparatus (GA) impacts on cell invasion are poorly understood. The human Golgi Anti-Apoptotic Protein (hGAAP, also known as TMBIM4) is a highly conserved Golgi cation channel that modulates...
Calcium cell invasion Golgi Apparatus Hydrogen Peroxide metabolism TMBIM Animals Calcium Signaling Cell Adhesion Cell Line Tumor Cell Movement Cell Survival Humans Hydrogen Peroxide MCF-7 Cells Membrane Proteins Mice Mitochondria Neoplasm Invasiveness Neoplasm Transplantation Neoplasms Reactive Oxygen Species Up-Regulation
Stimulation of cell invasion by the Golgi Ion Channel GAAP/TMBIM4 via an H2O2-Dependent Mechanism.
Nuno Almeida, Guia Carrara, Carlos M Palmeira, Ana S Fernandes, Maddy Parsons, Geoffrey L Smith, Nuno Saraiva
Dec 10, 2019
The mechanisms by which the Golgi apparatus (GA) impacts on cell invasion are poorly understood. The human Golgi Anti-Apoptotic Protein (hGAAP, also known as TMBIM4) is a highly conserved Golgi cation channel that modulates...
Nuclear calcium signatures are associated with root development.
In plants, nuclear Ca2+ releases are essential to the establishment of nitrogen-fixing and phosphate-delivering arbuscular mycorrhizal endosymbioses. In the legume Medicago truncatula, these nuclear Ca2+ signals are generated by...
A Transcriptomic Analysis of Xylan Mutants Does Not Support the Existence of a Secondary Cell Wall Integrity System in Arabidopsis.
Yeast have long been known to possess a cell wall integrity (CWI) system, and recently an analogous system has been described for the primary walls of plants (PCWI) that leads to changes in plant growth and cell wall...
Soil reinforcement through addition and subsequent carbonation of wollasonite microfibres
This study describes the application of wollasonite microfibres for stabilising soil with the additional function of sequestering CO2. The high aspect ratio, needle-like structure of wollasonite imparted a microfibre mechanical...
Immunocapture of <i>Escherichia coli</i> in a fluoropolymer microcapillary array
This study presents novel experimental insights into the direct quantitation and immunocapture of bacteria cells in a fluoropolymer microcapillary array, using Escherichia coli as work model, a pathogen responsible for around...
Microfluidic smartphone quantitation of <i>Escherichia coli</i> in synthetic urine
In spite of the clinical need, there is a major gap in rapid diagnostics for identification and quantitation of E. coli and other pathogens, also regarded as the biggest bottleneck in the fight against the spread of...
Transparent, Hydrophobic Fluorinated Ethylene Propylene Offers Rapid, Robust, and Irreversible Passive Adsorption of Diagnostic Antibodies for Sensitive Optical Biosensing
Current literature data is scarce and somehow contradictory in respect to the suitability of "nonstick" fluoropolymer surfaces for immobilization of biomolecules. We have previously shown empirically that transparent Teflon...
Teflon FEP Adsorption kinetics antibody adsorption biosensing microcapillary film Microfluidics /dk/atira/pure/subjectarea/asjc/2500/2502 name=Biomaterials /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry /dk/atira/pure/subjectarea/asjc/2200/2204 name=Biomedical Engineering /dk/atira/pure/subjectarea/asjc/2700/2704 name=Biochemistry, medical
Mind the Gap
The way organelles are viewed by cell biologists is quickly changing. For many years, these cellular entities were thought to be unique and singular structures that performed specific roles. However, in recent decades...
Microfluidic smartphone quantitation of <i>Escherichia coli</i> in synthetic urine
In spite of the clinical need, there is a major gap in rapid diagnostics for identification and quantitation of E. coli and other pathogens, also regarded as the biggest bottleneck in the fight against the spread of...
Transparent, Hydrophobic Fluorinated Ethylene Propylene Offers Rapid, Robust, and Irreversible Passive Adsorption of Diagnostic Antibodies for Sensitive Optical Biosensing
Current literature data is scarce and somehow contradictory in respect to the suitability of "nonstick" fluoropolymer surfaces for immobilization of biomolecules. We have previously shown empirically that transparent Teflon...
Teflon FEP Adsorption kinetics antibody adsorption biosensing microcapillary film Microfluidics /dk/atira/pure/subjectarea/asjc/2500/2502 name=Biomaterials /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry /dk/atira/pure/subjectarea/asjc/2200/2204 name=Biomedical Engineering /dk/atira/pure/subjectarea/asjc/2700/2704 name=Biochemistry, medical
Evaluating genetic drift in time-series evolutionary analysis.
The Wright-Fisher model is the most popular population model for describing the behaviour of evolutionary systems with a finite population size. Approximations have commonly been used but the model itself has rarely been tested...
The effects of maturity matched and un-matched opposition on physical performance and spatial exploration behavior during youth basketball matches
The aim of this study was analyze the effect of playing against biological matched and un-matched opposition, on physical performance and spatial exploration behavior of youth basketball players. Thirty under-14 to 16 basketball...
Artefactual nanoparticle activation of the inflammasome platform
AIM: To determine whether in vitro experimental conditions dictate cellular activation of the inflammasome by apatitic calcium phosphate nanoparticles. MATERIAL & METHODS: The responses of blood-derived primary human cells to in...
A New Zebrafish Model to Measure Neuronal α-Synuclein Clearance In Vivo
The accumulation and aggregation of α-synuclein (α-SYN) is a common characteristic of synucleinopathies, such as Parkinson’s Disease (PD), Dementia with Lewy Bodies (DLB) or Multiple System Atrophy (MSA). Multiplications of the...
The effects of maturity matched and un-matched opposition on physical performance and spatial exploration behavior during youth basketball matches
The aim of this study was analyze the effect of playing against biological matched and un-matched opposition, on physical performance and spatial exploration behavior of youth basketball players. Thirty under-14 to 16 basketball...
Immunocapture of <i>Escherichia coli</i> in a fluoropolymer microcapillary array
This study presents novel experimental insights into the direct quantitation and immunocapture of bacteria cells in a fluoropolymer microcapillary array, using Escherichia coli as work model, a pathogen responsible for around...
Sustainable soil stabilisation with ground granulated blast-furnace slag activated by olivine and sodium hydroxide
Mohammad Hamed Fasihnikoutalab, Shahram Pourakbar, Richard Ball, Cise Unuler, Nuno Cristelo
Jul 31, 2020
Ground granulated blast-furnace slag (GGBS), activated with olivine (Mg2SiO4) and sodium hydroxide (NaOH), was used to stabilise a clayey soil. Mechanical and microstructural properties of the stabilised soil were assessed...
Soil reinforcement through addition and subsequent carbonation of wollasonite microfibres
This study describes the application of wollasonite microfibres for stabilising soil with the additional function of sequestering CO2. The high aspect ratio, needle-like structure of wollasonite imparted a microfibre mechanical...
Fast prototyping using 3D printed templates and flexible fluoropolymer microcapillary films offers enhanced micromixing in immobilised (bio)catalytic reactions
Microreactors offer large surface-area-to-volume (SAV) ratios and short diffusion distances, yet, even at sub-millimetre space, there remains a level of mass transfer control of reactions. This can be minimised using passive...
3D printing Immobilised enzymatic reactions Mass transfer Micromixers Microreactor RTD /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry /dk/atira/pure/subjectarea/asjc/2300/2304 name=Environmental Chemistry /dk/atira/pure/subjectarea/asjc/1500/1500 name=General Chemical Engineering /dk/atira/pure/subjectarea/asjc/2200/2209 name=Industrial and Manufacturing Engineering
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