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The neuroblast timer gene nubbin exhibits functional redundancy with gap genes to regulate segment identity in Tribolium.
The neuroblast timer genes hunchback, Krüppel, nubbin and castor are expressed in temporal sequence in neural stem cells, and in corresponding spatial sequence along the Drosophila blastoderm. As canonical gap genes, hunchback...
Tribolium castaneum castor nubbin Gap gene Hox gene Neuroblast Animals Blastoderm Body Patterning DNA-Binding Proteins Drosophila Embryonic Development Female Gene Expression Gene Expression Regulation Developmental Gene Regulatory Networks Genes Homeobox Homeodomain Proteins Insect Proteins Male Neural Stem Cells POU Domain Factors RNA Interference Repressor Proteins Tribolium
Precarietà allora/ora
Adalgisa Giorgio
Dec 01, 2011
The author provides a reflection and ‘long vision’ on the term ‘precariousness’ by means of the microhistory of the members of her high school class in Southern Italy in the late 1970s. She traces their life and career paths...
Precarietà allora/ora
Adalgisa Giorgio
Dec 01, 2011
The author provides a reflection and ‘long vision’ on the term ‘precariousness’ by means of the microhistory of the members of her high school class in Southern Italy in the late 1970s. She traces their life and career paths...
Fatal infantile mitochondrial encephalomyopathy, hypertrophic cardiomyopathy and optic atrophy associated with a homozygous OPA1 mutation.
Ronen Spiegel, Ann Saada, Padraig J Flannery, Florence Burté, Devorah Soiferman, Morad Khayat, Verónica Eisner, Eugene Vladovski, Robert W Taylor, Laurence A Bindoff, Avraham Shaag, Hanna Mandel, Ora Schuler-Furman, Stavit A Shalev, Orly Elpeleg, Patrick Yu-Wai-Man
Jun 28, 2018
BACKGROUND: Infantile-onset encephalopathy and hypertrophic cardiomyopathy caused by mitochondrial oxidative phosphorylation defects are genetically heterogeneous with defects involving both the mitochondrial and nuclear...
Rituximab as therapy to induce remission after relapse in ANCA-associated vasculitis.
Rona M Smith, Rachel Bronwen Jones, Ulrich Specks, Simon Bond, Marianna Nodale, Reem Aljayyousi, Jacqueline Andrews, Annette Bruchfeld, Brian Camilleri, Simon Carette, Chee Kay Cheung, Vimal Derebail, Tim Doulton, Lindsy Forbess, Shouichi Fujimoto, Shunsuke Furuta, Ora Gewurz-Singer, Lorraine Harper, Toshiko Ito-Ihara, Nader Khalidi, Rainer Klocke, Curry Koening, Yoshinori Komagata, Carol Langford, Peter Lanyon, Raashid Ahmed Luqmani, Hirofumi Makino, Carole A McAlear, Paul Monach, Larry W Moreland, Kim Mynard, Patrick Nachman, Christian Pagnoux, Fiona Pearce, Chen Au Peh, Charles Pusey, Dwarakanathan Ranganathan, Rennie L Rhee, Robert Spiera, Antoine G Sreih, Vladimir Tesar, Giles Walters, Michael H Weisman, Caroline Wroe, Peter A Merkel, David Jayne, RITAZAREM coinvestigators, RITAZAREM co-investigators
May 06, 2020
B cells Granulomatosis with polyangiitis Systemic Vasculitis Treatment Adult Aged Aged 80 and over Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Antirheumatic Agents Drug Therapy Combination Female Glucocorticoids Humans Induction Chemotherapy Male Middle Aged Prospective Studies Recurrence Rituximab Treatment Outcome Young Adult
Rituximab versus azathioprine for maintenance of remission for patients with ANCA-associated vasculitis and relapsing disease
Rona M Smith, Rachel B Jones, Ulrich Specks, Simon Bond, Marianna Nodale, Reem Al-Jayyousi, Jacqueline Andrews, Annette Bruchfeld, Brian Camilleri, Simon Carette, Chee Kay Cheung, Vimal Derebail, Tim Doulton, Alastair Ferraro, Lindsy Forbess, Shouichi Fujimoto, Shunsuke Furuta, Ora Gewurz-Singer, Lorraine Harper, Toshiko Ito-Ihara, Nader Khalidi, Rainer Klocke, Curry Koening, Yoshinori Komagata, Carol Langford, Peter Lanyon, Raashid Luqmani, Carol McAlear, Larry W Moreland, Kim Mynard, Patrick Nachman, Christian Pagnoux, Chen Au Peh, Charles Pusey, Dwarakanathan Ranganathan, Rennie L Rhee, Robert Spiera, Antoine G Sreih, Vladamir Tesar, Giles Walters, Caroline Wroe, David Jayne, Peter A Merkel, RITAZAREM co-investigators
Mar 29, 2023
Rituximab as therapy to induce remission after relapse in ANCA-associated vasculitis
Rona M Smith, Rachel Bronwen Jones, Ulrich Specks, Simon Bond, Marianna Nodale, Reem Aljayyousi, Jacqueline Andrews, Annette Bruchfeld, Brian Camilleri, Simon Carette, Chee Kay Cheung, Vimal Derebail, Tim Doulton, Lindsy Forbess, Shouichi Fujimoto, Shunsuke Furuta, Ora Gewurz-Singer, Lorraine Harper, Toshiko Ito-Ihara, Nader Khalidi, Rainer Klocke, Curry Koening, Yoshinori Komagata, Carol Langford, Peter Lanyon, Raashid Ahmed Luqmani, Hirofumi Makino, Carole McAlear, Paul Monach, Larry W Moreland, Kim Mynard, Patrick Nachman, Christian Pagnoux, Fiona Pearce, Chen Au Peh, Charles Pusey, Dwarakanathan Ranganathan, Rennie L Rhee, Robert Spiera, Antoine G Sreih, Vladimir Tesar, Giles Walters, Michael H Weisman, Caroline Wroe, Peter Merkel, David Jayne, RITAZAREM co-investigators, Y Arimura, M Clarkson, J de Zoysa, T Endo, Y Hamano, H Kono, S Lawman, E Muso, K Sada, R Smith, K Suzuki, T Tsukamoto, S Uchida, A Vaglio, R Watts
Jun 26, 2020
A randomised trial of anti-GM-CSF otilimab in severe COVID-19 pneumonia (OSCAR).
Jatin Patel, Damon Bass, Albertus Beishuizen, Xavier Bocca Ruiz, Hatem Boughanmi, Anthony Cahn, Hugo Colombo, Gerard J Criner, Katherine Davy, Javier de-Miguel-Díez, Pablo A Doreski, Sofia Fernandes, Bruno François, Anubha Gupta, Kate Hanrott, Timothy Hatlen, Dave Inman, John D Isaacs, Emily Jarvis, Natalia Kostina, Tatiana Kropotina, Jean-Claude Lacherade, Divya Lakshminarayanan, Pedro Martinez-Ayala, Charlene McEvoy, Ferhat Meziani, Mehran Monchi, Sumanta Mukherjee, Rosana Muñoz-Bermúdez, Jessica Neisen, Ciara O'Shea, Gaëtan Plantefeve, Lorrie Schifano, Lee E Schwab, Zainab Shahid, Michinori Shirano, Julia E Smith, Eduardo Sprinz, Charlotte Summers, Nicolas Terzi, Mark A Tidswell, Yuliya Trefilova, Russell Williamson, Duncan Wyncoll, Mark Layton
Nov 16, 2022
BACKGROUND: Granulocyte-macrophage colony-stimulating factor (GM-CSF) and dysregulated myeloid cell responses are implicated in the pathophysiology and severity of COVID-19. METHODS: In this randomised, sequential, multicentre...
Molecular evolutionary trends and feeding ecology diversification in the Hemiptera, anchored by the milkweed bug genome.
Kristen A Panfilio, Iris M Vargas Jentzsch, Joshua B Benoit, Deniz Erezyilmaz, Yuichiro Suzuki, Stefano Colella, Hugh M Robertson, Monica F Poelchau, Robert M Waterhouse, Panagiotis Ioannidis, Matthew T Weirauch, Daniel ST Hughes, Shwetha C Murali, John H Werren, Chris GC Jacobs, Elizabeth J Duncan, David Armisén, Barbara MI Vreede, Patrice Baa-Puyoulet, Chloé S Berger, Chun-Che Chang, Hsu Chao, Mei-Ju M Chen, Yen-Ta Chen, Christopher P Childers, Ariel D Chipman, Andrew G Cridge, Antonin JJ Crumière, Peter K Dearden, Elise M Didion, Huyen Dinh, Harsha Vardhan Doddapaneni, Amanda Dolan, Shannon Dugan, Cassandra G Extavour, Gérard Febvay, Markus Friedrich, Neta Ginzburg, Yi Han, Peter Heger, Christopher J Holmes, Thorsten Horn, Yi-Min Hsiao, Emily C Jennings, J Spencer Johnston, Tamsin E Jones, Jeffery W Jones, Abderrahman Khila, Stefan Koelzer, Viera Kovacova, Megan Leask, Sandra L Lee, Chien-Yueh Lee, Mackenzie R Lovegrove, Hsiao-Ling Lu, Yong Lu, Patricia J Moore, Monica C Munoz-Torres, Donna M Muzny, Subba R Palli, Nicolas Parisot, Leslie Pick, Megan L Porter, Jiaxin Qu, Peter N Refki, Rose Richter, Rolando Rivera-Pomar, Andrew J Rosendale, Siegfried Roth, Lena Sachs, M Emília Santos, Jan Seibert, Essia Sghaier, Jayendra N Shukla, Richard J Stancliffe, Olivia Tidswell, Lucila Traverso, Maurijn van der Zee, Séverine Viala, Kim C Worley, Evgeny M Zdobnov, Richard A Gibbs, Stephen Richards
Apr 18, 2019
BACKGROUND: The Hemiptera (aphids, cicadas, and true bugs) are a key insect order, with high diversity for feeding ecology and excellent experimental tractability for molecular genetics. Building upon recent sequencing of...
Evolution of development Gene family evolution Gene structure Lateral gene transfer Phytophagy RNAi Transcription Factors Amino Acid Sequence Animals CYS2-HIS2 Zinc Fingers evolution Molecular Feeding Behavior Gene Dosage Gene Expression Profiling Gene Transfer Horizontal Genes Homeobox Genome Insect hemiptera Pigmentation Smell Transcription Factors