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A simple spatial extension to the extended connectivity interaction features for binding affinity prediction
The representation of the protein-ligand complexes used in building machine learning models play an important role in the accuracy of binding affinity prediction. The Extended Connectivity Interaction Features (ECIF) is one such...
A simple spatial extension to the extended connectivity interaction features for binding affinity prediction.
The representation of the protein-ligand complexes used in building machine learning models play an important role in the accuracy of binding affinity prediction. The Extended Connectivity Interaction Features (ECIF) is one such...
Batched Bayesian Optimization for Drug Design in Noisy Environments.
The early stages of the drug design process involve identifying compounds with suitable bioactivities via noisy assays. As databases of possible drugs are often very large, assays can only be performed on a subset of the...
A simple spatial extension to the extended connectivity interaction features for binding affinity prediction.
The representation of the protein-ligand complexes used in building machine learning models play an important role in the accuracy of binding affinity prediction. The Extended Connectivity Interaction Features (ECIF) is one such...
An evaluation of machine-learning for predicting phenotype
In phenotype prediction the physical characteristics of an organism are predicted from knowledge of its genotype and environment. Such studies, often called genome-wide association studies, are of the highest societal...
Predicting rice phenotypes with meta and multi-target learning
Abstract: The features in some machine learning datasets can naturally be divided into groups. This is the case with genomic data, where features can be grouped by chromosome. In many applications it is common for these...
An evaluation of machine-learning for predicting phenotype
Abstract: In phenotype prediction the physical characteristics of an organism are predicted from knowledge of its genotype and environment. Such studies, often called genome-wide association studies, are of the highest societal...
An evaluation of machine-learning for predicting phenotype
Abstract: In phenotype prediction the physical characteristics of an organism are predicted from knowledge of its genotype and environment. Such studies, often called genome-wide association studies, are of the highest societal...
Batched Bayesian Optimization for Drug Design in Noisy Environments.
The early stages of the drug design process involve identifying compounds with suitable bioactivities via noisy assays. As databases of possible drugs are often very large, assays can only be performed on a subset of the...
Nearest Neighbor Decoding and Pilot-AidedChannel Estimation for Fading Channels
We study the information rates of noncoherent, stationary, Gaussian, and multiple-input multiple-output (MIMO) flat-fading channels that are achievable with nearest neighbor decoding and pilot-aided channel estimation. In...
Naturalism<i>in extremis</i>
Claire White
Oct 08, 2015
Nearest Neighbor Decoding and Pilot-AidedChannel Estimation for Fading Channels
We study the information rates of noncoherent, stationary, Gaussian, and multiple-input multiple-output (MIMO) flat-fading channels that are achievable with nearest neighbor decoding and pilot-aided channel estimation. In...
Multi-Class Cost-Constrained Random Coding for Correlated Sources over the Multiple-Access Channel.
This paper studies a generalized version of multi-class cost-constrained random-coding ensemble with multiple auxiliary costs for the transmission of N correlated sources over an N-user multiple-access channel. For...
<i>‘Court’ing Hindu nationalism</i>
Saumya Saxena
Dec 11, 2018
Of
<i>reaflac</i>
and
<i>rapina</i>
Brittany Hanlon
Jan 04, 2023
This article examines the meaning and function of the Old English noun reaflac in two tenth‐century lawsuit documents, Sawyer 877 and Sawyer 1211. It suggests that reaflac was the vernacular counterpart to the Latin terms...
A novel bacteriophage cocktail reduces and disperses <i style="box-sizing: border-box; color: rgb(28, 29, 30); font-family: "Open Sans", icomoon, sans-serif; font-size: 18px;">P</i><i style="box-sizing: border-box; color: rgb(28, 29, 30); font-family: "Open Sans", icomoon, sans-serif; font-size
Diana Alves, Patricia Pérez Esteban, W Kot, Jessica Bean, Thomas Arnot, LH Hansen, Mark Enright, Andrew Jenkins
Jan 01, 2016
Pseudomonas aeruginosa is an opportunistic human pathogen that forms highly stable communities - biofilms, which contribute to the establishment and maintenance of infections. The biofilm state and intrinsic / acquired...
A novel bacteriophage cocktail reduces and disperses <i style="box-sizing: border-box; color: rgb(28, 29, 30); font-family: "Open Sans", icomoon, sans-serif; font-size: 18px;">P</i><i style="box-sizing: border-box; color: rgb(28, 29, 30); font-family: "Open Sans", icomoon, sans-serif; font-size
Diana Alves, Patricia Pérez Esteban, W Kot, Jessica Bean, Thomas Arnot, LH Hansen, Mark Enright, Andrew Jenkins
Jan 01, 2016
Pseudomonas aeruginosa is an opportunistic human pathogen that forms highly stable communities - biofilms, which contribute to the establishment and maintenance of infections. The biofilm state and intrinsic / acquired...
Population biology and phenology of the colour polymorphic damselfly
<i>Ischnura elegans</i>
at its southern range limit in Cyprus
1. Geographically widespread species provide excellent opportunities to investigate how phenotypes change across large‐scale environmental gradients. Temperature is a fundamental environmental variable and an important...
The <i>JWST</i> FRESCO Survey
P A Oesch, G Brammer, R P Naidu, R J Bouwens, J Chisholm, G D Illingworth, J Matthee, E Nelson, Y Qin, N Reddy, A Shapley, I Shivaei, P van Dokkum, A Weibel, K Whitaker, S Wuyts, A Covelo-Paz, R Endsley, Y Fudamoto, E Giovinazzo, T Herard-Demanche, J Kerutt, I Kramarenko, I Labbe, E Leonova, J Lin, D Magee, D Marchesini, M Maseda, C Mason, J Matharu, R A Meyer, C Neufeld, G Prieto Lyon, D Schaerer, R Sharma, M Shuntov, R Smit, M Stefanon, J S B Wyithe, M Xiao
Oct 31, 2023
We present the JWST cycle 1 53.8 h medium program FRESCO, short for 'First Reionization Epoch Spectroscopically Complete Observations'. FRESCO covers 62 arcmin2 in each of the two GOODS/CANDELS fields for a total area of 124...
The <i>JWST</i> FRESCO Survey
P A Oesch, G Brammer, R P Naidu, R J Bouwens, J Chisholm, G D Illingworth, J Matthee, E Nelson, Y Qin, N Reddy, A Shapley, I Shivaei, P van Dokkum, A Weibel, K Whitaker, S Wuyts, A Covelo-Paz, R Endsley, Y Fudamoto, E Giovinazzo, T Herard-Demanche, J Kerutt, I Kramarenko, I Labbe, E Leonova, J Lin, D Magee, D Marchesini, M Maseda, C Mason, J Matharu, R A Meyer, C Neufeld, G Prieto Lyon, D Schaerer, R Sharma, M Shuntov, R Smit, M Stefanon, J S B Wyithe, M Xiao
Oct 31, 2023
We present the JWST cycle 1 53.8 h medium program FRESCO, short for 'First Reionization Epoch Spectroscopically Complete Observations'. FRESCO covers 62 arcmin2 in each of the two GOODS/CANDELS fields for a total area of 124...
<i>Ixodes ricinus</i> Salivary Serpin Iripin-8 Inhibits the Intrinsic Pathway of Coagulation and Complement.
Jan Kotál, Stéphanie G I Polderdijk, Helena Langhansová, Monika Ederová, Larissa A Martins, Zuzana Beránková, Adéla Chlastáková, Ondřej Hajdušek, Michail Kotsyfakis, James A Huntington, Jindřich Chmelař
Oct 13, 2021
Tick saliva is a rich source of antihemostatic, anti-inflammatory, and immunomodulatory molecules that actively help the tick to finish its blood meal. Moreover, these molecules facilitate the transmission of tick-borne...
Published by: International journal of molecular sciences
Exploring the Impact of Terminators on Transgene Expression in <i>Chlamydomonas reinhardtii</i> with a Synthetic Biology Approach.
Katrin Geisler, Mark A Scaife, Paweł M Mordaka, Andre Holzer, Eleanor V Tomsett, Payam Mehrshahi, Gonzalo I Mendoza Ochoa, Alison G Smith
Oct 29, 2021
Chlamydomonas reinhardtii has many attractive features for use as a model organism for both fundamental studies and as a biotechnological platform. Nonetheless, despite the many molecular tools and resources that have...
A farewell to <i>R</i>
The time-dependent reproduction number, Rt, is a key metric used by epidemiologists to assess the current state of an outbreak of an infectious disease. This quantity is usually estimated using...
Electronic and optical properties of spinel zinc ferrite
Daniel Fritsch
Feb 14, 2018
Spinel ferrites in general show a rich interplay of structural, electronic, and magnetic properties. Here, we particularly focus on zinc ferrite (ZFO), which has been observed experimentally to crystallise in the cubic normal...
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