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Results: 155
A kinase-independent function of PAK is crucial for pathogen-mediated actin remodelling.
The p21-activated kinase (PAK) family regulate a multitude of cellular processes, including actin cytoskeleton remodelling. Numerous bacterial pathogens usurp host signalling pathways that regulate actin reorganisation in order...
Complete Genome Sequence of Pseudomonas aeruginosa Reference Strain PAK.
Amy K Cain, Laura M Nolan, Geraldine J Sullivan, Cynthia B Whitchurch, Alain Filloux, Julian Parkhill
Nov 20, 2019
We report the complete genome of Pseudomonas aeruginosa strain PAK, a strain which has been instrumental in the study of a range of P. aeruginosa virulence and pathogenesis factors and has been used for over 50 years as a...
Development of System Typology and Choice of Preferred Simulation Modelling Methods for DSS-Toolkit
Oleg Dmitriev
Jan 01, 2022
This paper formulated a position on the feasibility of developing and applying a highly developed simulation models of complex object within scope of justifying of managerial decisions. It selected a set of classification...
Published by: IGI Global Scientific Publishing
Logic of the Powers
Pak Nung Wong
Jul 30, 2021
What global future would ensure hope, justice and peace to the human mankind? In view of a fast evolving post-Covid world order, this volume explores a novel Christian post-colonial approach to global affairs. It examines the...
Published by: Routledge
Techno-Geopolitics
Pak Nung Wong
Sep 24, 2021
Techno-Geopolitics explores contemporary U.S.–China relations and the future of global cyber-security through the prisms of geopolitics and financial-technological competition. It puts forward a new conceptual framework for an...
/dk/atira/pure/sustainabledevelopmentgoals/decent_work_and_economic_growth name=SDG 8 - Decent Work and Economic Growth
Published by: Routledge
Open Science, Bandung and Ezekiel
Pak Nung Wong
Nov 07, 2017
To explore a new de-colonial option for the global future, this article grapples with three movements of our time: the ‘Open Science’ movement, the 1955 African-Asian conference and the Non-Aligned Movement, and the post-exilic...
Techno-Geopolitics
Pak Nung Wong
Sep 24, 2021
Techno-Geopolitics explores contemporary U.S.–China relations and the future of global cyber-security through the prisms of geopolitics and financial-technological competition. It puts forward a new conceptual framework for an...
/dk/atira/pure/sustainabledevelopmentgoals/decent_work_and_economic_growth name=SDG 8 - Decent Work and Economic Growth
Published by: Routledge
Impact of the mitochondria-targeted antioxidant MitoQ on hypoxia-induced pulmonary hypertension.
Oleg Pak, Susan Scheibe, Azadeh Esfandiary, Mareike Gierhardt, Akylbek Sydykov, Angela Logan, Athanasios Fysikopoulos, Florian Veit, Matthias Hecker, Florian Kroschel, Karin Quanz, Alexandra Erb, Katharina Schäfer, Mirja Fassbinder, Nasim Alebrahimdehkordi, Hossein A Ghofrani, Ralph T Schermuly, Ralf P Brandes, Werner Seeger, Michael P Murphy, Norbert Weissmann, Natascha Sommer
Jun 18, 2018
Increased mitochondrial reactive oxygen species (ROS), particularly superoxide have been suggested to mediate hypoxic pulmonary vasoconstriction (HPV), chronic hypoxia-induced pulmonary hypertension (PH) and right ventricular...
Open Science, Bandung and Ezekiel
Pak Nung Wong
Nov 07, 2017
To explore a new de-colonial option for the global future, this article grapples with three movements of our time: the ‘Open Science’ movement, the 1955 African-Asian conference and the Non-Aligned Movement, and the post-exilic...
Logic of the Powers
Pak Nung Wong
Jul 30, 2021
What global future would ensure hope, justice and peace to the human mankind? In view of a fast evolving post-Covid world order, this volume explores a novel Christian post-colonial approach to global affairs. It examines the...
Published by: Routledge
A generative model for age and income distribution
Abstract Each individual in society experiences an evolution of their income during their lifetime. Macroscopically, this dynamic creates a statistical relationship between age and income for each...
Inferring extrinsic noise from single-cell gene expression data using approximate Bayesian computation.
BACKGROUND: Gene expression is known to be an intrinsically stochastic process which can involve single-digit numbers of mRNA molecules in a cell at any given time. The modelling of such processes calls for the use of exact...
Human Computer Interaction During Clinical Decision Support With Electronic Health Records Improvement
Katerina Bolgova, Sergey Kovalchuk, Marina Balakhontceva, Nadezhda Zvartau, Oleg Metsker
Jan 01, 2020
This study investigated the most common challenges of human-computer interaction (HCI) while using electronic health records (EHR) based on the experience of a large Russian medical research center. The article presents the...
Published by: IGI Global Scientific Publishing
Behavioural deficits in transgenic mice expressing human truncated (1-120 amino acid) alpha-synuclein.
ALPHA-SYNUCLEIN dementia with Lewy bodies Memory neurodegeneration Transgenic mouse Age Factors Animals Calcium-Calmodulin-Dependent Protein Kinase Type 2 Disease Models Animal Exploratory Behavior Gene Expression Regulation Humans Lewy Body Disease Male Maze Learning Mice Mice Inbred C57BL Mice Transgenic Peptide Fragments Prosencephalon RNA Messenger ALPHA-SYNUCLEIN
Evaluation of transabdominal and transperineal ultrasound-derived prostate specific antigen (PSA) density and clinical utility compared to MRI prostate volumes
Maria Pantelidou, Iztok Caglic, Anne George, Oleg Blyuss, Vincent J Gnanapragasam, Tristan Barrett
Sep 09, 2022
PURPOSE: To investigate the accuracy of surface-based ultrasound-derived PSA-density (US-PSAD) versus gold-standard MRI-PSAD as a risk-stratification tool. METHODS: Single-centre prospective study of patients undergoing MRI for...
MRI-derived radiomics model for baseline prediction of prostate cancer progression on active surveillance
Nikita Sushentsev, Leonardo Rundo, Oleg Blyuss, Vincent J. Gnanapragasam, Evis Sala, Tristan Barrett
Jun 21, 2021
Abstract: Nearly half of patients with prostate cancer (PCa) harbour low- or intermediate-risk disease considered suitable for active surveillance (AS). However, up to 44% of patients discontinue AS within the first five years...
Evaluation of transabdominal and transperineal ultrasound-derived prostate specific antigen (PSA) density and clinical utility compared to MRI prostate volumes
Maria Pantelidou, Iztok Caglic, Anne George, Oleg Blyuss, Vincent J Gnanapragasam, Tristan Barrett
Oct 12, 2022
PURPOSE: To investigate the accuracy of surface-based ultrasound-derived PSA-density (US-PSAD) versus gold-standard MRI-PSAD as a risk-stratification tool. METHODS: Single-centre prospective study of patients undergoing MRI for...
MRI-derived radiomics model for baseline prediction of prostate cancer progression on active surveillance.
Nikita Sushentsev, Leonardo Rundo, Oleg Blyuss, Vincent J Gnanapragasam, Evis Sala, Tristan Barrett
Jun 04, 2021
Field effect transistors and phototransistors based upon p-type solution-processed PbS nanowires.
Paul Giraud, Bo Hou, Sangyeon Pak, Jung Inn Sohn, Stephen Morris, SeungNam Cha, Jong Min Kim
Dec 13, 2018
We demonstrate the fabrication of solution processed highly crystalline p-type PbS nanowires via the oriented attachment of nanoparticles. The analysis of single nanowire field effect transistor (FET) devices revealed a hole...
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