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Docosahexaenoic Acid Supplementation in Pregnancy Modulates Placental Cellular Signaling and Nutrient Transport Capacity in Obese Women.
Susanne Lager, Vanessa I Ramirez, Ometeotl Acosta, Christiane Meireles, Evelyn Miller, Francesca Gaccioli, Fredrick J Rosario, Jonathan AL Gelfond, Kevin Hakala, Susan T Weintraub, Debra A Krummel, Theresa L Powell
Apr 05, 2018
CONTEXT: Maternal obesity in pregnancy has profound impacts on maternal metabolism and promotes placental nutrient transport, which may contribute to fetal overgrowth in these pregnancies. The fatty acid docosahexaenoic acid...
Development of an Infection-Responsive Fluorescent Sensor for the Early Detection of Urinary Catheter Blockage
Scarlet Milo, Florianne B. Acosta, Hollie J. Hathaway, Laura A. Wallace, Naing T. Thet, Andrew Jenkins
Mar 23, 2018
Formation of crystalline biofilms following infection by Proteus mirabilis can lead to encrustation and blockage of longterm indwelling catheters, with serious clinical consequences. We describe a simple sensor, placed within...
Proteus mirabilis Biofilms carboxyfluorescein Indwelling catheter sensor /dk/atira/pure/subjectarea/asjc/1500/1502 name=Bioengineering /dk/atira/pure/subjectarea/asjc/1500/1507 name=Fluid Flow and Transfer Processes /dk/atira/pure/subjectarea/asjc/1500/1508 name=Process Chemistry and Technology /dk/atira/pure/subjectarea/asjc/3100/3105 name=Instrumentation
Oxidised alginate hydrogels as niche environments for corneal epithelial cells
Bernice Wright, Paul A. De Bank, Kimberley Luetchford, Fernando R. Acosta, Che J. Connon
Oct 01, 2014
Chemical and biochemical modification of hydrogels is one strategy to create physiological constructs that maintain cell function. The aim of this study was to apply oxidised alginate hydrogels as a basis for development of a...
Development of an Infection-Responsive Fluorescent Sensor for the Early Detection of Urinary Catheter Blockage
Scarlet Milo, Florianne B. Acosta, Hollie J. Hathaway, Laura A. Wallace, Naing T. Thet, Andrew Jenkins
Mar 23, 2018
Formation of crystalline biofilms following infection by Proteus mirabilis can lead to encrustation and blockage of longterm indwelling catheters, with serious clinical consequences. We describe a simple sensor, placed within...
Proteus mirabilis Biofilms carboxyfluorescein Indwelling catheter sensor /dk/atira/pure/subjectarea/asjc/1500/1502 name=Bioengineering /dk/atira/pure/subjectarea/asjc/1500/1507 name=Fluid Flow and Transfer Processes /dk/atira/pure/subjectarea/asjc/1500/1508 name=Process Chemistry and Technology /dk/atira/pure/subjectarea/asjc/3100/3105 name=Instrumentation
Oxidised alginate hydrogels as niche environments for corneal epithelial cells
Bernice Wright, Paul A. De Bank, Kimberley Luetchford, Fernando R. Acosta, Che J. Connon
Oct 01, 2014
Chemical and biochemical modification of hydrogels is one strategy to create physiological constructs that maintain cell function. The aim of this study was to apply oxidised alginate hydrogels as a basis for development of a...
Neighbourhood environment and dementia in older people from high-, middle- and low-income countries
Yu-Tzu Wu, Carol Brayne, Zhaorui Liu, Yueqin Huang, Ana Luisa Sosa, Daisy Acosta, Matthew Prina
Sep 10, 2020
BACKGROUND: A growing number of studies have explored how features of the neighbourhood environment can be related to cognitive health in later life. Yet few have focused on low- and middle-income countries and compared the...
Built environment Dementia Epidemiological cohorts geographic information system Green and blue spaces Local amenities older people Aged Aged 80 and over China Cognition Cohort Studies Cross-Sectional Studies Dementia Developed Countries Developing Countries Dominican Republic Female Geriatric Assessment Humans Logistic Models Male Mental Status and Dementia Tests Mexico Residence Characteristics Social Environment United Kingdom
Classification of brain tumours from MR spectra
Margarida Julià-Sapé, John R Griffiths, A Rosemary Tate, Franklyn A Howe, Dionisio Acosta, Geert Postma, Joshua Underwood, Carles Majós, Carles Arús
Oct 06, 2015
Sensitivity to pain expectations
The thoughts and feelings people have about pain (referred to as 'pain expectations') are known to alter the perception of pain. However little is known about the cognitive processes that underpin pain expectations, or what...
The Extended Continental Crust West of Islas Marías (Mexico)
The crustal structure around the Islas Marías Archipelago has been debated for a long time. An important unresolved question is where the Rivera-North American plate subduction ends and the Tamayo fracture zone begins...
Brain-predicted age in Down syndrome is associated with beta amyloid deposition and cognitive decline.
James H Cole, Tiina Annus, Liam R Wilson, Ridhaa Remtulla, Young T Hong, Tim D Fryer, Julio Acosta-Cabronero, Arturo Cardenas-Blanco, Robert Smith, David K Menon, Shahid H Zaman, Peter J Nestor, Anthony J Holland
Apr 06, 2018
Notch Signaling Mediates Secondary Senescence.
Yee Voan Teo, Nattaphong Rattanavirotkul, Nelly Olova, Angela Salzano, Andrea Quintanilla, Nuria Tarrats, Christos Kiourtis, Miryam Müller, Anthony R Green, Peter D Adams, Juan-Carlos Acosta, Thomas G Bird, Kristina Kirschner, Nicola Neretti, Tamir Chandra
Apr 17, 2019
CEBPB Notch TGFB bystander senescence oncogene induced senescence paracrine senescence secondary senescence Senescence senescence associated secretory phenotype single-cell RNA sequencing Animals Cells Cultured Cellular Senescence Humans Mice Inbred C57BL Oncogenes Receptors Notch Signal Transduction Single-Cell Analysis Transcriptome
Neighbourhood environment and dementia in older people from high-, middle- and low-income countries
Yu-Tzu Wu, Carol Brayne, Zhaorui Liu, Yueqin Huang, Ana Luisa Sosa, Daisy Acosta, Matthew Prina
Sep 02, 2020
Abstract: Background: A growing number of studies have explored how features of the neighbourhood environment can be related to cognitive health in later life. Yet few have focused on low- and middle-income countries and...
Neighbourhood environment and dementia in older people from high-, middle- and low-income countries
Yu-Tzu Wu, Carol Brayne, Zhaorui Liu, Yueqin Huang, Ana Luisa Sosa, Daisy Acosta, Matthew Prina
Sep 01, 2021
Abstract: Background: A growing number of studies have explored how features of the neighbourhood environment can be related to cognitive health in later life. Yet few have focused on low- and middle-income countries and...
Intrinsically disordered protein biosensor tracks the physical-chemical effects of osmotic stress on cells.
Cesar L Cuevas-Velazquez, Tamara Vellosillo, Karina Guadalupe, Hermann Broder Schmidt, Feng Yu, David Moses, Jennifer A N Brophy, Dante Cosio-Acosta, Alakananda Das, Lingxin Wang, Alexander M Jones, Alejandra A Covarrubias, Shahar Sukenik, José R Dinneny
Oct 18, 2021
Cell Line Tumor Osteoblasts Humans Escherichia coli Saccharomyces cerevisiae Arabidopsis water Molecular Chaperones Arabidopsis Proteins Recombinant Proteins Fluorescence Resonance Energy Transfer Biosensing Techniques Gene Expression Binding Sites Protein Conformation Protein Binding Kinetics Osmolar Concentration Osmotic Pressure Thermodynamics Models Molecular Protein Interaction Domains and Motifs Intrinsically Disordered Proteins
Published by: Nature Communications
Brown Adipose Tissue Volume and Fat Content Are Positively Associated With Whole-Body Adiposity in Young Men-Not in Women.
Guillermo Sanchez-Delgado, Borja Martinez-Tellez, Francisco M Acosta, Samuel Virtue, Antonio Vidal-Puig, Angel Gil, Jose M Llamas-Elvira, Jonatan R Ruiz
Apr 23, 2021
Human brown adipose tissue (BAT) volume has consistently been claimed to be inversely associated with whole-body adiposity. However, recent advances in the assessment of human BAT suggest that previously reported associations...
In vivo visualization of age-related differences in the locus coeruleus.
Kathy Y Liu, Julio Acosta-Cabronero, Arturo Cardenas-Blanco, Clare Loane, Alex J Berry, Matthew J Betts, Rogier A Kievit, Richard N Henson, Emrah Düzel, Cam-CAN, Robert Howard, Dorothea Hämmerer
Dec 18, 2018
The locus coeruleus (LC), the major origin of noradrenergic modulation of the central nervous system, may play an important role in neuropsychiatric disorders including Parkinson's disease and Alzheimer's disease. The pattern of...
AI4People
David Danks, Christoph Lütge, Franziska Poszler, Aida Acosta, Gail Gottehrer, Lucian Mihet-Popa, Aisha Naseer
Jan 01, 2021
This paper presents the work of the AI4People-Automotive Committee established to advise more concretely on specific ethical issues that arise from autonomous vehicles (AVs). Practical recommendations for the automotive sector...
Published by: IGI Global Scientific Publishing
Excess deaths associated with covid-19 pandemic in 2020
Nazrul Islam, Vladimir M Shkolnikov, Rolando J Acosta, Ilya Klimkin, Ichiro Kawachi, Rafael A Irizarry, Gianfranco Alicandro, Kamlesh Khunti, Tom Yates, Dmitri A Jdanov, Martin White, Sarah Lewington, Ben Lacey
May 21, 2021
Abstract: Objective: To estimate the direct and indirect effects of the covid-19 pandemic on mortality in 2020 in 29 high income countries with reliable and complete age and sex disaggregated mortality data. Design: Time series...
Cardiovascular Risk Detection Through Big Data Analysis
Cardiovascular diseases are the main cause of mortality in the world. As more people suffer from diabetes and hypertension, the risk of cardiovascular disease (CVD) increases. A sedentary lifestyle, an unhealthy diet, and...
Published by: IGI Global Scientific Publishing
Combination of Genome-Scale Models and Bioreactor Dynamics to Optimize the Production of Commodity Chemicals
Jorge Lázaro, Giorgio Jansen, Yiheng Yang, Mario A Torres-Acosta, Gary Lye, Stephen G Oliver, Jorge Júlvez
May 11, 2022
The current production of a number of commodity chemicals relies on the exploitation of fossil fuels and hence has an irreversible impact on the environment. Biotechnological processes offer an attractive alternative by enabling...
Drug therapies for peripheral joint disease in psoriatic arthritis
Maria Laura Acosta Felquer, Laura C Coates, Enrique R Soriano, Roberto Ranza, Luis R Espinoza, Philip S Helliwell, Oliver FitzGerald, Neil McHugh, Euthalia Roussou, Philip J Mease
Nov 01, 2014
In 2009, GRAPPA published their first evidence-based recommendations for the treatment of psoriasis and psoriatic arthritis (PsA). Since then, new information has been published and drugs developed. We summarize evidence for the...
Drug therapies for peripheral joint disease in psoriatic arthritis
Maria Laura Acosta Felquer, Laura C Coates, Enrique R Soriano, Roberto Ranza, Luis R Espinoza, Philip S Helliwell, Oliver FitzGerald, Neil McHugh, Euthalia Roussou, Philip J Mease
Nov 01, 2014
In 2009, GRAPPA published their first evidence-based recommendations for the treatment of psoriasis and psoriatic arthritis (PsA). Since then, new information has been published and drugs developed. We summarize evidence for the...
BLOC-1 and BLOC-3 regulate VAMP7 cycling to and from melanosomes via distinct tubular transport carriers.
Megan K Dennis, Cédric Delevoye, Amanda Acosta-Ruiz, Ilse Hurbain, Maryse Romao, Geoffrey G Hesketh, Philip S Goff, Elena V Sviderskaya, Dorothy C Bennett, J Paul Luzio, Thierry Galli, David J Owen, Graça Raposo, Michael S Marks
Aug 18, 2016
Animals Carrier Proteins Cell Membrane Endocytosis Green Fluorescent Proteins Humans Intracellular Signaling Peptides and Proteins Lectins Melanocytes Melanosomes Membrane Glycoproteins Mice Inbred C57BL Mitochondrial Proteins Nerve Tissue Proteins Oxidoreductases Pigmentation Protein Transport Qa-SNARE Proteins R-SNARE Proteins Recombinant Fusion Proteins Transport Vesicles rab GTP-Binding Proteins
Excess deaths associated with covid-19 pandemic in 2020
Nazrul Islam, Vladimir M Shkolnikov, Rolando J Acosta, Ilya Klimkin, Ichiro Kawachi, Rafael A Irizarry, Gianfranco Alicandro, Kamlesh Khunti, Tom Yates, Dmitri A Jdanov, Martin White, Sarah Lewington, Ben Lacey
May 03, 2021
Intrinsically disordered protein biosensor tracks the physical-chemical effects of osmotic stress on cells.
Cesar L Cuevas-Velazquez, Tamara Vellosillo, Karina Guadalupe, Hermann Broder Schmidt, Feng Yu, David Moses, Jennifer AN Brophy, Dante Cosio-Acosta, Alakananda Das, Lingxin Wang, Alexander M Jones, Alejandra A Covarrubias, Shahar Sukenik, José R Dinneny
Nov 22, 2021
Cell homeostasis is perturbed when dramatic shifts in the external environment cause the physical-chemical properties inside the cell to change. Experimental approaches for dynamically monitoring these intracellular effects are...
Arabidopsis Arabidopsis Proteins Binding Sites Biosensing Techniques Cell Line Tumor Escherichia coli Fluorescence Resonance Energy Transfer Gene Expression Humans Intrinsically Disordered Proteins Kinetics Models Molecular Molecular Chaperones Osmolar Concentration Osmotic Pressure Osteoblasts Protein Binding Protein Conformation Protein Interaction Domains and Motifs Recombinant Proteins Saccharomyces cerevisiae Thermodynamics water
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