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Results: 40
F-Actin nucleated on chromosomes coordinates their capture by microtubules in oocyte meiosis.
Capture of each and every chromosome by spindle microtubules is essential to prevent chromosome loss and aneuploidy. In somatic cells, astral microtubules search and capture chromosomes forming lateral attachments to...
Centrosome function is critical during terminal erythroid differentiation.
Red blood cells are produced by terminal erythroid differentiation, which involves the dramatic morphological transformation of erythroblasts into enucleated reticulocytes. Microtubules are important for enucleation, but it is...
Quantitative interpretation explains machine learning models for chemical reaction prediction and uncovers bias
Abstract: Organic synthesis remains a major challenge in drug discovery. Although a plethora of machine learning models have been proposed as solutions in the literature, they suffer from being opaque black-boxes. It is neither...
A disassembly-driven mechanism explains F-actin-mediated chromosome transport in starfish oocytes.
While contraction of sarcomeric actomyosin assemblies is well understood, this is not the case for disordered networks of actin filaments (F-actin) driving diverse essential processes in animal cells. For example, at the onset...
Ubiquitylation of Drosophila p54/Rpn10/S5a regulates its interaction with the UBA-UBL polyubiquitin receptors.
Quantitative interpretation explains machine learning models for chemical reaction prediction and uncovers bias.
Organic synthesis remains a major challenge in drug discovery. Although a plethora of machine learning models have been proposed as solutions in the literature, they suffer from being opaque black-boxes. It is neither clear if...
Developmental and tissue specific changes of ubiquitin forms in Drosophila melanogaster.
In most Eukaryotes, ubiquitin either exists as free monoubiquitin or as a molecule that is covalently linked to other proteins. These two forms cycle between each other and due to the concerted antagonistic activity of...
The role of agri-environment schemes in conservation and environmental management.
Common Agricultural Policy Europa Europe European Union Política Agrícola Común Unión Europea agricultural intensification farmland field margin grassland intensificación agrícola manejo orgánico margen del campo organic management pastizal tierra de cultivo agriculture Biodiversity Conservation of Natural Resources Cost-Benefit Analysis Ecosystem Environmental Policy Europe History 20th Century History 21st Century
Role of the deubiquitylating enzyme DmUsp5 in coupling ubiquitin equilibrium to development and apoptosis in Drosophila melanogaster.
Protein ubiquitylation is a dynamic process that affects the function and stability of proteins and controls essential cellular processes ranging from cell proliferation to cell death. This process is regulated through the...
Detection and Identification of Microbial Volatile Organic Compounds of the Green Mold Disease
Button mushrooms are one of the most commonly cultivated mushroom species facing different risks e.g.: viral, bacterial and fungal diseases. One of the most common problems is caused by Trichoderma aggressivum, or ‘green mould'...
Published by: IGI Global Scientific Publishing
Complement lectin pathway activation is associated with COVID-19 disease severity, independent of MBL2 genotype subgroups
Lisa Hurler, Ágnes Szilágyi, Federica Mescia, Laura Bergamaschi, Blanka Mező, György Sinkovits, Marienn Réti, Veronika Müller, Zsolt Iványi, János Gál, László Gopcsa, Péter Reményi, Beáta Szathmáry, Botond Lakatos, János Szlávik, Ilona Bobek, Zita Z Prohászka, Zsolt Förhécz, Dorottya Csuka, Erika Kajdácsi, László Cervenak, Petra Kiszel, Tamás Masszi, István Vályi-Nagy, Reinhard Würzner, Paul A Lyons, Erik JM Toonen, Zoltán Prohászka
Apr 10, 2023
Celecoxib Prevents Doxorubicin-Induced Multidrug Resistance in Canine and Mouse Lymphoma Cell Lines.
Edina Karai, Kornélia Szebényi, Tímea Windt, Sára Fehér, Eszter Szendi, Valéria Dékay, Péter Vajdovich, Gergely Szakács, András Füredi
Jul 17, 2020
BACKGROUND: Treatment of malignancies is still a major challenge in human and canine cancer, mostly due to the emergence of multidrug resistance (MDR). One of the main contributors of MDR is the overexpression P-glycoprotein...
Celecoxib Prevents Doxorubicin-Induced Multidrug Resistance in Canine and Mouse Lymphoma Cell Lines
Edina Karai, Kornélia Szebényi, Tímea Windt, Sára Fehér, Eszter Szendi, Valéria Dékay, Péter Vajdovich, Gergely Szakács, András Füredi
Apr 30, 2020
Background: Treatment of malignancies is still a major challenge in human and canine cancer, mostly due to the emergence of multidrug resistance (MDR). One of the main contributors of MDR is the overexpression P-glycoprotein...
Reference exome data for Australian Aboriginal populations to support health-based research
Alexia L. Weeks, Heather A. D’Antoine, Melita McKinnon, Genevieve Syn, Dawn Bessarab, Ngiare Brown, Steven Y. C. Tong, Bo Reményi, Andrew Steer, Lesley-Ann Gray, Michael Inouye, Jonathan R. Carapetis, Jenefer M. Blackwell, Timo Lassmann
Feb 16, 2021
Abstract: Whole exome sequencing (WES) is a popular and successful technology which is widely used in both research and clinical settings. However, there is a paucity of reference data for Aboriginal Australians to underpin the...
A CEP215-HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer.
Pavithra L Chavali, Gayathri Chandrasekaran, Alexis R Barr, Péter Tátrai, Chris Taylor, Evaggelia K Papachristou, C Geoffrey Woods, Sreenivas Chavali, Fanni Gergely
Feb 10, 2016
An optimised transformation protocol for Anthoceros agrestis and three more hornwort species.
Manuel Waller, Eftychios Frangedakis, Alan O Marron, Susanna Sauret-Gueto, Jenna Rever, Cyrus Raja Rubenstein Sabbagh, Julian M Hibberd, Jim Haseloff, Karen Renzaglia, Péter Szövényi
Apr 11, 2023
Step-by-step protocol for the isolation and transient transformation of hornwort protoplasts.
Anna Neubauer, Stéphanie Ruaud, Manuel Waller, Eftychios Frangedakis, Fay-Wei Li, Svenja I Nötzold, Susann Wicke, Aurélien Bailly, Péter Szövényi
Jun 07, 2022
PREMISE: A detailed protocol for the protoplast transformation of hornwort tissue is not yet available, limiting molecular biological investigations of these plants and comparative analyses with other bryophytes, which display a...
Step-by-step protocol for the isolation and transient transformation of hornwort protoplasts.
Anna Neubauer, Stéphanie Ruaud, Manuel Waller, Eftychios Frangedakis, Fay-Wei Li, Svenja I Nötzold, Susann Wicke, Aurélien Bailly, Péter Szövényi
Feb 11, 2022
Premise: A detailed protocol for the protoplast transformation of hornwort tissue is not yet available, limiting molecular biological investigations of these plants and comparative analyses with other bryophytes, which display a...
Irreproducibility in searches of scientific literature
Gábor Pozsgai, Gábor L Lövei, Liette Vasseur, Geoff Gurr, Péter Batáry, János Korponai, Nick A Littlewood, Jian Liu, Arnold Móra, John Obrycki, Olivia Reynolds, Jenni A Stockan, Heather VanVolkenburg, Jie Zhang, Wenwu Zhou, Minsheng You
Oct 18, 2021
Repeatability is the cornerstone of science, and it is particularly important for systematic reviews. However, little is known on how researchers' choice of database, and search platform influence the repeatability of systematic...
What can hornworts teach us?
Eftychios Frangedakis, Alan O Marron, Manuel Waller, Anna Neubauer, Sze Wai Tse, Yuling Yue, Stephanie Ruaud, Lucas Waser, Keiko Sakakibara, Péter Szövényi
Mar 22, 2023
Reference exome data for Australian Aboriginal populations to support health-based research.
Alexia L Weeks, Heather A D'Antoine, Melita McKinnon, Genevieve Syn, Dawn Bessarab, Ngiare Brown, Steven YC Tong, Bo Reményi, Andrew Steer, Lesley-Ann Gray, Michael Inouye, Jonathan R Carapetis, Jenefer M Blackwell, Timo Lassmann
May 20, 2020
Whole exome sequencing (WES) is a popular and successful technology which is widely used in both research and clinical settings. However, there is a paucity of reference data for Aboriginal Australians to underpin the...
Reference exome data for Australian Aboriginal populations to support health-based research
Alexia L. Weeks, Heather A. D’Antoine, Melita McKinnon, Genevieve Syn, Dawn Bessarab, Ngiare Brown, Steven Y. C. Tong, Bo Reményi, Andrew Steer, Lesley-Ann Gray, Michael Inouye, Jonathan R. Carapetis, Jenefer M. Blackwell, Timo Lassmann
Apr 29, 2021
Abstract: Whole exome sequencing (WES) is a popular and successful technology which is widely used in both research and clinical settings. However, there is a paucity of reference data for Aboriginal Australians to underpin the...
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