Many cancers express mutant p53 proteins that have lost wild-type tumor suppressor activity and, in many cases, have acquired oncogenic functions that can contribute to tumor progression. These activities of mutant p53 reflect...
The gastro-intestinal tract is the most extensive mucosal surface in mammals and harbors the most numerous immune cell reservoir as well as a complex and autonomous nervous system. The GI tract is continuously exposed to foreign...
Cetaceans possess brains that rank among the largest to have ever evolved, either in terms of absolute mass or relative to body size. Cetaceans have evolved these huge brains under relatively unique environmental conditions...
In previous publications, we found that the membrane of macrophage phagolysosomes could be selectively radioiodinated in living cells. The technique required phagocytosis of lactoperoxidase covalently coupled to latex spheres...
A method has been developed to deliver an iodinating system into the confines of the phagolysosome, allowing us to study the nature of the phagolysosomal membrane. Lactoperoxidase (LPO) is covalently coupled to carboxylated...
We describe investigations of the largely unexplored field of mesoscopic type-I superconductors. Micromagnetometry and 3D Ginzburg-Landau simulations of our single crystal β-tin samples in this regime reveal size- and...
The shape evolution of mesoscopic tin crystals electrodeposited on boron-doped diamond (BDD) substrates is described as a function of the ion concentration and deposition potential. Concentrations of 5-100 mM Sn(II) in 1 M...
The shape evolution of mesoscopic tin crystals electrodeposited on boron-doped diamond (BDD) substrates is described as a function of the ion concentration and deposition potential. Concentrations of 5-100 mM Sn(II) in 1 M...
We have studied electron states present at the Pb(111) surface above Ar-fillednanocavities created by ion beam irradiation and annealing. Vertical confinement between the parallel crystal and nanocavity surfaces creates a series...
Using a scanning tunneling microscope, confined electron states are studied that exist above subsurface nanometer-sized voids at Pb(111), where potential barriers at the parallel vacuum–Pb(111) and Pb(111)–void interfaces...
In this paper we analyze inexact inverse iteration for the nonsymmetric generalized eigenvalue problem Ax = λMx, where M is symmetric positive definite and the problem is diagonalizable. Our analysis is designed to apply to the...
Senior Alex Muller, president of the Winthrop Iota Mu Chapter of Sigma Tau Delta and editor of the Winthrop Literary Magazine The Anthology, was awarded the $4,000 Sigma Tau Delta Senior Scholarship for his outstanding scholarly...
A method has been developed to deliver an iodinating system into the confines of the phagolysosome, allowing us to study the nature of the phagolysosomal membrane. Lactoperoxidase (LPO) is covalently coupled to carboxylated...