Search
Results: 537
Which Neuropsychological Tests? Predicting Cognitive Decline and Dementia in Parkinson's Disease in the ICICLE-PD Cohort.
Rachael A Lawson, Caroline H Williams-Gray, Marta Camacho, Gordon W Duncan, Tien K Khoo, David P Breen, Roger A Barker, Lynn Rochester, David J Burn, Alison J Yarnall, ICICLE-PD study group
May 28, 2021
BACKGROUND: Cognitive impairment is common in Parkinson's disease (PD), with 80% cumulatively developing dementia (PDD). OBJECTIVE: We sought to identify tests that are sensitive to change over time above normal ageing so as to...
On the appearance of nitrite anion in [PdX(OAc)L<sub>2</sub>] and [Pd(X)(C∧N)L] syntheses (X = OAc or NO<sub>2</sub>)
S E Bajwa, T E Storr, Lauren E Hatcher, T J Williams, C G Baumann, A C Whitwood, D R Allan, S J Teat, Paul R Raithby, I J S Fairlamb
May 01, 2012
Pd 3(OAc) 5NO 2, an impurity in "Pd(OAc) 2" {formally Pd 3(OAc) 6}, emerges as a serious issue in the synthesis of pure Pd II complexes derived from Pd(OAc) 2, for example in our C-H activation precatalyst, Pd(OAc) 2(pip) 2 (pip...
On the appearance of nitrite anion in [PdX(OAc)L<sub>2</sub>] and [Pd(X)(C∧N)L] syntheses (X = OAc or NO<sub>2</sub>)
S E Bajwa, T E Storr, Lauren E Hatcher, T J Williams, C G Baumann, A C Whitwood, D R Allan, S J Teat, Paul R Raithby, I J S Fairlamb
May 01, 2012
Pd 3(OAc) 5NO 2, an impurity in "Pd(OAc) 2" {formally Pd 3(OAc) 6}, emerges as a serious issue in the synthesis of pure Pd II complexes derived from Pd(OAc) 2, for example in our C-H activation precatalyst, Pd(OAc) 2(pip) 2 (pip...
ALMA Observations of the HD 110058 Debris Disk
Abstract
We present Atacama Large Millimeter/submillimeter Array (ALMA) observations of the young, gas-rich debris disk around HD 110058 at 0.″3–0.″6 resolution. The disk is...
AS Hales, S Marino, PD Sheehan, S Ulloa, S Pérez, L Matrà, Q Kral, M Wyatt, W Dent, J Carpenter
Dec 08, 2022
Cognitive decline and quality of life in incident Parkinson's disease
Rachael A Lawson, Alison J Yarnall, Gordon W Duncan, David P Breen, Tien K Khoo, Caroline H Williams-Gray, Roger A Barker, Daniel Collerton, John-Paul Taylor, David J Burn, ICICLE-PD study group
Apr 12, 2018
INTRODUCTION: Parkinson's disease dementia (PDD) is associated with poorer quality of life (QoL). Prior to the onset of PDD, many patients experience progressive cognitive impairment. There is a paucity of longitudinal studies...
Cinnamaldehyde hydrogenation using Au–Pd catalysts prepared by sol immobilisation
Stefano Cattaneo, Simon J Freakley, David J Morgan, Meenakshisundaram Sankar, Nikolaos Dimitratos, Graham J Hutchings
Mar 21, 2018
We report the catalytic performance of Au–Pd nanoparticles prepared via a sol immobilisation technique for the catalytic hydrogenation of cinnamaldehyde under mild reaction conditions. We synthesised a series of bimetallic Au–Pd...
The direct synthesis of hydrogen peroxide from H<sub>2</sub> and O<sub>2</sub> using Pd-Ni/TiO<sub>2</sub> catalysts
David A. Crole, Ricci Underhill, Jennifer K. Edwards, Greg Shaw, Simon J. Freakley, Graham J. Hutchings, Richard J. Lewis
Jul 24, 2020
The direct synthesis of hydrogen peroxide (H2O2) from molecular H2 and O2 offers an attractive, decentralized alternative to production compared to the current means of production, the anthraquinone process. Herein we...
Green chemistry Hydrogen Peroxide Nanoparticles Nickel Palladium /dk/atira/pure/subjectarea/asjc/2600/2600 name=General Mathematics /dk/atira/pure/subjectarea/asjc/2200/2200 name=General Engineering /dk/atira/pure/subjectarea/asjc/3100/3100 name=General Physics and Astronomy /dk/atira/pure/sustainabledevelopmentgoals/decent_work_and_economic_growth name=SDG 8 - Decent Work and Economic Growth /dk/atira/pure/sustainabledevelopmentgoals/responsible_consumption_and_production name=SDG 12 - Responsible Consumption and Production
Cognitive impairment in Parkinson's disease
RA Lawson, AJ Yarnall, F Johnston, GW Duncan, TK Khoo, D Collerton, JP Taylor, DJ Burn, ICICLE-PD study group
Apr 12, 2018
BACKGROUND: The quality of life (QoL) of informal caregivers of people with Parkinson's disease (PD) (PwP) can be affected by the caring role. Because of cognitive symptoms and diminished activities of daily living, in addition...
The direct synthesis of hydrogen peroxide from H<sub>2</sub> and O<sub>2</sub> using Pd-Ni/TiO<sub>2</sub> catalysts
David A. Crole, Ricci Underhill, Jennifer K. Edwards, Greg Shaw, Simon J. Freakley, Graham J. Hutchings, Richard J. Lewis
Jul 24, 2020
The direct synthesis of hydrogen peroxide (H2O2) from molecular H2 and O2 offers an attractive, decentralized alternative to production compared to the current means of production, the anthraquinone process. Herein we...
Green chemistry Hydrogen Peroxide Nanoparticles Nickel Palladium /dk/atira/pure/subjectarea/asjc/2600/2600 name=General Mathematics /dk/atira/pure/subjectarea/asjc/2200/2200 name=General Engineering /dk/atira/pure/subjectarea/asjc/3100/3100 name=General Physics and Astronomy /dk/atira/pure/sustainabledevelopmentgoals/decent_work_and_economic_growth name=SDG 8 - Decent Work and Economic Growth /dk/atira/pure/sustainabledevelopmentgoals/responsible_consumption_and_production name=SDG 12 - Responsible Consumption and Production
Stability of mild cognitive impairment in newly diagnosed Parkinson's disease.
Rachael A Lawson, Alison J Yarnall, Gordon W Duncan, David P Breen, Tien K Khoo, Caroline H Williams-Gray, Roger A Barker, David J Burn, ICICLE-PD study group
Aug 16, 2017
BACKGROUND: Mild cognitive impairment (MCI) is common in early Parkinson's disease (PD). We evaluated the stability of PD-MCI over time to determine its clinical utility as a marker of disease. METHODS: 212 newly diagnosed...
Porous Nanocrystalline Silicon Supported Bimetallic Pd-Au Catalysts
Dmitriy I Potemkin, Dmitry K Maslov, Konstantin Loponov, Pavel V Snytnikov, Yuri V Shubin, Pavel E Plyusnin, Dmitry A Svintsitskiy, Vladimir A Sobyanin, Alexei A Lapkin
Feb 06, 2019
Bimetallic Pd-Au catalysts were prepared on the porous nanocrystalline silicon (PSi) for the first time. The catalysts were tested in the reaction of direct hydrogen peroxide synthesis and characterized by standard structural...
Pro-Saccades Predict Cognitive Decline in Parkinson's Disease
Samuel Stuart, Rachael A Lawson, Alison J Yarnall, Jeremy Nell, Lisa Alcock, Gordon W Duncan, Tien K Khoo, Roger A Barker, Lynn Rochester, David J Burn, ICICLE-PD study group
Jul 24, 2019
Embracing Monogenic Parkinson's Disease
Eva-Juliane Vollstedt, Susen Schaake, Katja Lohmann, Shalini Padmanabhan, Alexis Brice, Suzanne Lesage, Christelle Tesson, Marie Vidailhet, Isabel Wurster, Faycel Hentati, Anat Mirelman, Nir Giladi, Karen Marder, Cheryl Waters, Stanley Fahn, Meike Kasten, Norbert Brüggemann, Max Borsche, Tatiana Foroud, Eduardo Tolosa, Alicia Garrido, Grazia Annesi, Monica Gagliardi, Maria Bozi, Leonidas Stefanis, Joaquim J Ferreira, Leonor Correia Guedes, Micol Avenali, Simona Petrucci, Lorraine Clark, Ekaterina Y Fedotova, Natalya Y Abramycheva, Victoria Alvarez, Manuel Menéndez-González, Silvia Jesús Maestre, Pilar Gómez-Garre, Pablo Mir, Andrea Carmine Belin, Caroline Ran, Chin-Hsien Lin, Ming-Che Kuo, David Crosiers, Zbigniew K Wszolek, Owen A Ross, Joseph Jankovic, Kenya Nishioka, Manabu Funayama, Jordi Clarimon, Caroline H Williams-Gray, Marta Camacho, Mario Cornejo-Olivas, Luis Torres-Ramirez, Yih-Ru Wu, Guey-Jen Lee-Chen, Ana Morgadinho, Teeratorn Pulkes, Pichet Termsarasab, Daniela Berg, Gregor Kuhlenbäumer, Andrea A Kühn, Friederike Borngräber, Giuseppe de Michele, Anna De Rosa, Alexander Zimprich, Andreas Puschmann, George D Mellick, Jolanta Dorszewska, Jonathan Carr, Rosangela Ferese, Stefano Gambardella, Bruce Chase, Katerina Markopoulou, Wataru Satake, Tatsushi Toda, Malco Rossi, Marcelo Merello, Timothy Lynch, Diana A Olszewska, Shen-Yang Lim, Azlina Ahmad-Annuar, Ai Huey Tan, Bashayer Al-Mubarak, Hasmet Hanagasi, Dariusz Koziorowski, Sibel Ertan, Gençer Genç, Patricia de Carvalho Aguiar, Melinda Barkhuizen, Marcia MG Pimentel, Rachel Saunders-Pullman, Bart van de Warrenburg, Susan Bressman, Mathias Toft, Silke Appel-Cresswell, Anthony E Lang, Matej Skorvanek, Agnita JW Boon, Rejko Krüger, Esther M Sammler, Vitor Tumas, Bao-Rong Zhang, Gaetan Garraux, Sun Ju Chung, Yun Joong Kim, Juliane Winkelmann, Carolyn M Sue, Eng-King Tan, Joana Damásio, Péter Klivényi, Vladimir S Kostic, David Arkadir, Mika Martikainen, Vanderci Borges, Jens Michael Hertz, Laura Brighina, Mariana Spitz, Oksana Suchowersky, Olaf Riess, Parimal Das, Brit Mollenhauer, Emilia M Gatto, Maria Skaalum Petersen, Nobutaka Hattori, Ruey-Meei Wu, Sergey N Illarioshkin, Enza Maria Valente, Jan O Aasly, Anna Aasly, Roy N Alcalay, Avner Thaler, Matthew J Farrer, Kathrin Brockmann, Jean-Christophe Corvol, Christine Klein, MJFF Global Genetic Parkinson's Disease Study Group
Jan 24, 2023
BACKGROUND: As gene-targeted therapies are increasingly being developed for Parkinson's disease (PD), identifying and characterizing carriers of specific genetic pathogenic variants is imperative. Only a small fraction of the...
Cinnamaldehyde hydrogenation using Au–Pd catalysts prepared by sol immobilisation
Stefano Cattaneo, Simon J Freakley, David J Morgan, Meenakshisundaram Sankar, Nikolaos Dimitratos, Graham J Hutchings
Mar 21, 2018
We report the catalytic performance of Au–Pd nanoparticles prepared via a sol immobilisation technique for the catalytic hydrogenation of cinnamaldehyde under mild reaction conditions. We synthesised a series of bimetallic Au–Pd...
Anxiety is associated with cognitive impairment in newly-diagnosed Parkinson's disease.
Nadeeka NW Dissanayaka, Rachael A Lawson, Alison J Yarnall, Gordon W Duncan, David P Breen, Tien K Khoo, Roger A Barker, David J Burn, ICICLE-PD study group
Aug 17, 2017
INTRODUCTION: Anxiety and mild cognitive impairment (MCI) are prevalent non-motor manifestations of Parkinson's disease (PD). While few studies have demonstrated a possible link between cognitive dysfunction and anxiety in PD...
Detailed structural analysis of amorphous Pd<sub>40</sub>Cu<sub>40</sub>P<sub>20</sub>
Shinya Hosokawa, Jean François Bérar, Nathalie Boudet, Wolf Christian Pilgrim, László Pusztai, Satoshi Hiroi, Shinji Kohara, Hidemi Kato, Henry E. Fischer, Anita Zeidler
Mar 01, 2021
To clarify the relationship between the glass-forming ability (GFA) and local atomic structure of Pd-based metallic glasses, the structures of an amorphous Pd40Cu40P20 (PCP) were investigated...
Anomalous X-ray scattering Glass-forming ability Hyper-ordered structures metallic glasses neutron diffraction Reverse Monte Carlo modeling /dk/atira/pure/subjectarea/asjc/2500/2504 name=Electronic, Optical and Magnetic Materials /dk/atira/pure/subjectarea/asjc/2500/2503 name=Ceramics and Composites /dk/atira/pure/subjectarea/asjc/3100/3104 name=Condensed Matter Physics /dk/atira/pure/subjectarea/asjc/2500/2505 name=Materials Chemistry
Fc-null anti-PD-1 monoclonal antibodies deliver optimal checkpoint blockade in diverse immune environments.
Julia Moreno-Vicente, Jane E Willoughby, Martin C Taylor, Steven G Booth, Vikki L English, Emily L Williams, Christine A Penfold, C Ian Mockridge, Tatyana Inzhelevskaya, Jinny Kim, HT Claude Chan, Mark S Cragg, Juliet C Gray, Stephen A Beers
Jan 28, 2022
BACKGROUND: Despite extensive clinical use, the mechanisms that lead to therapeutic resistance to anti-programmed cell-death (PD)-1 monoclonal antibodies (mAbs) remain elusive. Here, we sought to determine how interactions...
Genetic impact on cognition and brain function in newly diagnosed Parkinson's disease
Cristina Nombela, James B Rowe, Sophie E Winder-Rhodes, Adam Hampshire, Adrian M Owen, David P Breen, Gordon W Duncan, Tien K Khoo, Alison J Yarnall, Michael J Firbank, Patrick F Chinnery, Trevor W Robbins, John T O'Brien, David J Brooks, David J Burn, ICICLE-PD study group, Roger A Barker
Feb 02, 2016
Parkinson’s disease Cognition Functional MRI Genetics Aged Apolipoproteins E Brain Catechol O-Methyltransferase Cognition Cognition Disorders Cohort Studies Female Humans Image Processing Computer-Assisted Imagination Longitudinal Studies Magnetic Resonance Imaging Male Memory Middle Aged Mitogen-Activated Protein Kinases Neuroimaging Neuropsychological Tests Parkinson Disease Psychomotor Performance Rotation Space Perception tau Proteins
Isolated Pd Sites as Selective Catalysts for Electrochemical and Direct Hydrogen Peroxide Synthesis
Marc Ledendecker, Enrico Pizzutilo, Grazia Malta, Guilherme V. Fortunato, Karl J.J. Mayrhofer, Graham J. Hutchings, Simon J. Freakley
May 15, 2020
Palladium nanoparticles have been studied extensively as catalysts for the direct synthesis of hydrogen peroxide, where selectivity remains a key challenge. Alloying Pd with other metals and using acid and halide promoters...
Detailed structural analysis of amorphous Pd<sub>40</sub>Cu<sub>40</sub>P<sub>20</sub>
Shinya Hosokawa, Jean François Bérar, Nathalie Boudet, Wolf Christian Pilgrim, László Pusztai, Satoshi Hiroi, Shinji Kohara, Hidemi Kato, Henry E. Fischer, Anita Zeidler
Mar 01, 2021
To clarify the relationship between the glass-forming ability (GFA) and local atomic structure of Pd-based metallic glasses, the structures of an amorphous Pd40Cu40P20 (PCP) were investigated...
Anomalous X-ray scattering Glass-forming ability Hyper-ordered structures metallic glasses neutron diffraction Reverse Monte Carlo modeling /dk/atira/pure/subjectarea/asjc/2500/2504 name=Electronic, Optical and Magnetic Materials /dk/atira/pure/subjectarea/asjc/2500/2503 name=Ceramics and Composites /dk/atira/pure/subjectarea/asjc/3100/3104 name=Condensed Matter Physics /dk/atira/pure/subjectarea/asjc/2500/2505 name=Materials Chemistry
Synthesis and Reactivity of Stable Alkyl-Pd(IV) Complexes Relevant to Monodentate N-Directed C(sp3)-H Functionalization Processes.
Alkyl-Pd(IV) complexes are frequently invoked in the proposed mechanisms of Pd-catalyzed C(sp3)-H functionalization reactions, though few examples of Pd(IV) complexes containing cyclopalladated substrates have been isolated due...
Azathioprine immunosuppression and disease modification in Parkinson’s disease (AZA-PD)
Julia C Greenland, Emma Cutting, Sonakshi Kadyan, Simon Bond, Anita Chhabra, Caroline H Williams-Gray
Nov 26, 2020
Introduction: The immune system is implicated in the aetiology and progression of Parkinson’s disease (PD). Inflammation and immune activation occur both in the brain and in the periphery, and a proinflammatory cytokine profile...
Isolated Pd Sites as Selective Catalysts for Electrochemical and Direct Hydrogen Peroxide Synthesis
Marc Ledendecker, Enrico Pizzutilo, Grazia Malta, Guilherme V. Fortunato, Karl J.J. Mayrhofer, Graham J. Hutchings, Simon J. Freakley
May 15, 2020
Palladium nanoparticles have been studied extensively as catalysts for the direct synthesis of hydrogen peroxide, where selectivity remains a key challenge. Alloying Pd with other metals and using acid and halide promoters...
Progression of Neuropsychiatric Symptoms over Time in an Incident Parkinson’s Disease Cohort (ICICLE-PD)
J. K. Dlay, G. W. Duncan, T. K. Khoo, C. H. Williams-Gray, D. P. Breen, R. A. Barker, D. J. Burn, R. A. Lawson, A. J. Yarnall
Feb 03, 2020
Background: Cross-sectional studies have identified that the prevalence of neuropsychiatric symptoms (NPS) in Parkinson’s disease (PD) ranges from 70−89%. However, there are few longitudinal studies determining the impact of NPS...
|
|< |
< |
1 |