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The Variable CTCF Site from Drosophila melanogaster Ubx Gene is Redundant and Has no Insulator Activity.
CTCF is the most thoroughly studied chromatin architectural protein and it is found in both Drosophila and mammals. CTCF preferentially binds to promoters and insulators and is thought to facilitate formation of chromatin loops....
The Variable CTCF Site from Drosophila melanogaster Ubx Gene is Redundant and Has no Insulator Activity.
CTCF is the most thoroughly studied chromatin architectural protein and it is found in both Drosophila and mammals. CTCF preferentially binds to promoters and insulators and is thought to facilitate formation of chromatin loops....
Ecological selectivity and the evolution of mammalian substrate preference across the K–Pg boundary
Jonathan J. Hughes, Jacob S. Berv, Stephen G. B. Chester, Eric J. Sargis, Daniel J. Field
Oct 11, 2021
Abstract: The Cretaceous–Paleogene (K–Pg) mass extinction 66 million years ago was characterized by a worldwide ecological catastrophe and rapid species turnover. Large‐scale devastation of forested environments resulting from...
RESEARCH ARTICLE RESEARCH ARTICLES ancestral state reconstruction euarchontans marsupials Paleoecology placentals substrate use
Published by: Ecology and Evolution
Genomic signature of an avian Lilliput Effect across the K-Pg Extinction
Survivorship following major mass extinctions may be associated with a decrease in body size-a phenomenon called the Lilliput Effect. Body size is a strong predictor of many life history traits (LHTs), and is known to...
Birds K-Pg Body Size divergence times Life history evolution Mass extinction metabolic rate molecular clocks Life History Traits Extinction Biological Fossils Animals Amino Acid Substitution/genetics Body Size/genetics evolution Molecular /dk/atira/pure/subjectarea/asjc/1300/1311 name=Genetics /dk/atira/pure/subjectarea/asjc/1100/1105 name=Ecology, Evolution, Behavior and Systematics
Dinosaur diversification rates were not in decline prior to the K-Pg boundary
Determining the tempo and mode of non-avian dinosaur extinction is one of the most contentious issues in palaeobiology. Extensive disagreements remain over whether their extinction was catastrophic and geologically instantaneous...
Genomic signature of an avian Lilliput Effect across the K-Pg Extinction
Survivorship following major mass extinctions may be associated with a decrease in body size-a phenomenon called the Lilliput Effect. Body size is a strong predictor of many life history traits (LHTs), and is known to...
Birds K-Pg Body Size divergence times Life history evolution Mass extinction metabolic rate molecular clocks Life History Traits Extinction Biological Fossils Animals Amino Acid Substitution/genetics Body Size/genetics evolution Molecular /dk/atira/pure/subjectarea/asjc/1300/1311 name=Genetics /dk/atira/pure/subjectarea/asjc/1100/1105 name=Ecology, Evolution, Behavior and Systematics
Dinosaur diversification rates were not in decline prior to the K-Pg boundary
Determining the tempo and mode of non-avian dinosaur extinction is one of the most contentious issues in palaeobiology. Extensive disagreements remain over whether their extinction was catastrophic and geologically instantaneous...
Early Evolution of Modern Birds Structured by Global Forest Collapse at the End-Cretaceous Mass Extinction
Daniel Field, Antoine Bercovici, Jacob S Berv, Regan Dunn, David Fastovsky, Tyler R. Lyson, Vivi Vajda, Jacques Gauthier
Jun 04, 2018
The fossil record and recent molecular phylogenies support an extraordinary early-Cenozoic radiation of crown birds (Neornithes) after the Cretaceous-Paleogene (K-Pg) mass extinction [1–3]. However, questions remain regarding...
K-Pg Ancestral states Birds ecological selectivity Mass extinction Paleobotany /dk/atira/pure/subjectarea/asjc/1300/1300 name=General Biochemistry,Genetics and Molecular Biology /dk/atira/pure/subjectarea/asjc/1100/1100 name=General Agricultural and Biological Sciences /dk/atira/pure/sustainabledevelopmentgoals/life_on_land name=SDG 15 - Life on Land
Cultural Values and Its Influence on the Enactment of Leadership in Public Sector Organisations
Pg Idris
Oct 01, 2021
This research contributes to our understanding of leadership in public sector organisations by examining the influence of national culture on the enactment of public sector leadership in the context of Brunei. It followed a...
Published by: IGI Global Scientific Publishing
Trans-myocardial Extraction of Endothelin-1 Correlates with Increased Microcirculatory Resistance following Percutaneous Coronary Intervention.
George R Abraham, Duuamene Nyimanu, Rhoda E Kuc, Janet J Maguire, Anthony P Davenport, Stephen P Hoole
Nov 19, 2022
OBJECTIVE: Coronary microvascular dysfunction (CMD) can complicate successful percutaneous coronary intervention (PCI). The potent endogenous vasoconstrictor peptide Endothelin-1 (ET-1) may be an important mediator. To...
Early Evolution of Modern Birds Structured by Global Forest Collapse at the End-Cretaceous Mass Extinction
Daniel Field, Antoine Bercovici, Jacob S Berv, Regan Dunn, David Fastovsky, Tyler R. Lyson, Vivi Vajda, Jacques Gauthier
Jun 04, 2018
The fossil record and recent molecular phylogenies support an extraordinary early-Cenozoic radiation of crown birds (Neornithes) after the Cretaceous-Paleogene (K-Pg) mass extinction [1–3]. However, questions remain regarding...
K-Pg Ancestral states Birds ecological selectivity Mass extinction Paleobotany /dk/atira/pure/subjectarea/asjc/1300/1300 name=General Biochemistry,Genetics and Molecular Biology /dk/atira/pure/subjectarea/asjc/1100/1100 name=General Agricultural and Biological Sciences /dk/atira/pure/sustainabledevelopmentgoals/life_on_land name=SDG 15 - Life on Land
Circulating levels of angiogenic factors and their association with preeclampsia among pregnant women at Mulago National Referral Hospital in Uganda
Sheila Nabweyambo, Obondo James Sande, Naomi McGovern, Freddie Bwanga, Alfred Ssekagiri, Annette Keesiga, Moses Adroma, Ronald Wasswa, Maxine Atuheirwe, Juliet Namugenyi, Barbara Castelnuovo, Annettee Nakimuli
May 20, 2021
Preeclampsia (PE) is a major cause of maternal and new-born morbidity and mortality. Angiogenic factors contribute a major role in the vascular dysfunction associated with PE. We investigated the circulating levels of vascular...
Effects of Growth Rate on Peptidoglycan Crosslink Density of E. coli Using Fluorescent Labeling
Morgan Olszewski
Jan 01, 0001
Peptidoglycan (PG) is a polymer composed of polysaccharides and crosslinked peptide chains found in bacterial cell walls. It helps to protect the cell from environmental stress and maintain cell morphology throughout its life...
Published by: Harrisburg University of Science and Technology
Circulating levels of angiogenic factors and their association with preeclampsia among pregnant women at Mulago National Referral Hospital in Uganda.
Sheila Nabweyambo, Obondo James Sande, Naomi McGovern, Freddie Bwanga, Alfred Ssekagiri, Annette Keesiga, Moses Adroma, Ronald Wasswa, Maxine Atuheirwe, Juliet Namugenyi, Barbara Castelnuovo, Annettee Nakimuli
Jul 05, 2021
Preeclampsia (PE) is a major cause of maternal and new-born morbidity and mortality. Angiogenic factors contribute a major role in the vascular dysfunction associated with PE. We investigated the circulating levels of vascular...
Circulating levels of angiogenic factors and their association with preeclampsia among pregnant women at Mulago National Referral Hospital in Uganda.
Sheila Nabweyambo, Obondo James Sande, Naomi McGovern, Freddie Bwanga, Alfred Ssekagiri, Annette Keesiga, Moses Adroma, Ronald Wasswa, Maxine Atuheirwe, Juliet Namugenyi, Barbara Castelnuovo, Annettee Nakimuli
Jun 19, 2021
Preeclampsia (PE) is a major cause of maternal and new-born morbidity and mortality. Angiogenic factors contribute a major role in the vascular dysfunction associated with PE. We investigated the circulating levels of vascular...
Published by: PLOS ONE
Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration.
Julio C Rojas, Ping Wang, Adam M Staffaroni, Carolin Heller, Yann Cobigo, Amy Wolf, Sheng-Yang M Goh, Peter A Ljubenkov, Hilary W Heuer, Jamie C Fong, Joanne B Taylor, Eliseo Veras, Linan Song, Andreas Jeromin, David Hanlon, Lili Yu, Arvind Khinikar, Rajeev Sivasankaran, Agnieszka Kieloch, Marie-Anne Valentin, Anna M Karydas, Laura L Mitic, Rodney Pearlman, John Kornak, Joel H Kramer, Bruce L Miller, Kejal Kantarci, David S Knopman, Neill Graff-Radford, Leonard Petrucelli, Rosa Rademakers, David J Irwin, Murray Grossman, Eliana Marisa Ramos, Giovanni Coppola, Mario F Mendez, Yvette Bordelon, Bradford C Dickerson, Nupur Ghoshal, Edward D Huey, Ian R Mackenzie, Brian S Appleby, Kimiko Domoto-Reilly, Ging-Yuek R Hsiung, Arthur W Toga, Sandra Weintraub, Daniel I Kaufer, Diana Kerwin, Irene Litvan, Chiadikaobi U Onyike, Alexander Pantelyat, Erik D Roberson, Maria C Tartaglia, Tatiana Foroud, Weiping Chen, Julie Czerkowicz, Danielle L Graham, John C van Swieten, Barbara Borroni, Raquel Sanchez-Valle, Fermin Moreno, Robert Laforce, Caroline Graff, Matthis Synofzik, Daniela Galimberti, James B Rowe, Mario Masellis, Elizabeth Finger, Rik Vandenberghe, Alexandre de Mendonça, Fabrizio Tagliavini, Isabel Santana, Simon Ducharme, Chris R Butler, Alexander Gerhard, Johannes Levin, Adrian Danek, Markus Otto, Sandro Sorbi, David M Cash, Rhian S Convery, Martina Bocchetta, Martha Foiani, Caroline V Greaves, Georgia Peakman, Lucy Russell, Imogen Swift, Emily Todd, Jonathan D Rohrer, Bradley F Boeve, Howard J Rosen, Adam L Boxer, ALLFTD and GENFI consortia
Apr 13, 2021
OBJECTIVE: We tested the hypothesis that plasma neurofilament light chain (NfL) identifies asymptomatic carriers of familial frontotemporal lobar degeneration (FTLD)-causing mutations at risk of disease progression. METHODS...
Evolution and dispersal of snakes across the Cretaceous-Paleogene mass extinction.
Catherine G Klein, Davide Pisani, Daniel J Field, Rebecca Lakin, Matthew A Wills, Nicholas R Longrich
Oct 18, 2021
Mass extinctions have repeatedly shaped global biodiversity. The Cretaceous-Paleogene (K-Pg) mass extinction caused the demise of numerous vertebrate groups, and its aftermath saw the rapid diversification of surviving mammals...
Animals Birds Fishes Mammals Snakes Biodiversity Phylogeny Fossils History Ancient Genetic Speciation Extinction Biological Amphibians Phylogeography Animal Distribution DNA Ancient
Published by: Nature Communications
Saharan dust electrification perceived by a triangle of atmospheric electricity stations in Southern Portugal
HG Silva, F Lopes, S Pereira, Kerianne Nicoll, S M Barbosa, R Conceicao, S Neves, S Neves, Giles Harrison, M Collares Pereira
Dec 01, 2016
Atmospheric Electric Potential Gradient (PG) measurements were carried out in three sites forming a triangular array in Southern Portugal. The campaign was performed during the summer, characterized by Saharan dust outbreaks;...
Evolution and dispersal of snakes across the Cretaceous-Paleogene mass extinction.
Catherine G Klein, Davide Pisani, Daniel J Field, Rebecca Lakin, Matthew A Wills, Nicholas R Longrich
Sep 15, 2021
Mass extinctions have repeatedly shaped global biodiversity. The Cretaceous-Paleogene (K-Pg) mass extinction caused the demise of numerous vertebrate groups, and its aftermath saw the rapid diversification of surviving mammals...
Circulating levels of GDF15 in patients with myalgic encephalomyelitis/chronic fatigue syndrome.
BACKGROUND: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating condition characterised by fatigue and post-exertional malaise. Its pathogenesis is poorly understood. GDF15 is a circulating protein...
Chronic fatigue syndrome GDF15 Myalgic encephalomyelitis Adult Case-Control Studies Fatigue Syndrome Chronic Female Follow-Up Studies Growth Differentiation Factor 15 Humans Linear Models Longitudinal Studies Male Middle Aged Multivariate Analysis Outcome Assessment Health Care Self Report Time Factors
Circulating levels of GDF15 in patients with myalgic encephalomyelitis/chronic fatigue syndrome.
BACKGROUND:Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating condition characterised by fatigue and post-exertional malaise. Its pathogenesis is poorly understood. GDF15 is a circulating protein...
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