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Results: 480
Complotype affects the extent of down-regulation by Factor I of the C3b feedback cycle in vitro.
E Lay, S Nutland, JE Smith, I Hiles, RAG Smith, DJ Seilly, A Buchberger, W Schwaeble, PJ Lachmann
Oct 09, 2014
Lectin pathway effector enzyme mannan-binding lectin-associated serine protease-2 can activate native complement C3 in absence of C4 and/or C2.
Sadam Yaseen, Gregory Demopulos, Thomas Dudler, Munehisa Yabuki, Christi L Wood, W Jason Cummings, Larry W Tjoelker, Teizo Fujita, Steven Sacks, Peter Garred, Peter Andrew, Robert B Sim, Peter J Lachmann, Russell Wallis, Nicholas Lynch, Wilhelm J Schwaeble
Aug 05, 2019
All 3 activation pathways of complement-the classic pathway (CP), the alternative pathway, and the lectin pathway (LP)- converge into a common central event: the cleavage and activation of the abundant third complement...
Looking back on the alternative complement pathway.
Peter J Lachmann
Apr 30, 2019
The alternative pathway of complement originated from the Properdin pathway originally described by the Pillemer laboratory in the 1950s. This work generated great controversy and it took several decades for a consensus on its...
Fit Perceptions, Work Engagement, Satisfaction and Commitment
Purpose: The purpose of this paper is to explore the relationship between fit (organization and job) perceptions and work engagement (WE). Design/methodology/approach: The authors deployed a two-wave survey among 377 clerical...
job satisfaction Organizational Commitment Person–environment fit Work Engagement /dk/atira/pure/subjectarea/asjc/3200/3207 name=Social Psychology /dk/atira/pure/subjectarea/asjc/3200/3202 name=Applied Psychology /dk/atira/pure/subjectarea/asjc/1800/1803 name=Management Science and Operations Research /dk/atira/pure/subjectarea/asjc/1400/1407 name=Organizational Behavior and Human Resource Management
Fit Perceptions, Work Engagement, Satisfaction and Commitment
Purpose: The purpose of this paper is to explore the relationship between fit (organization and job) perceptions and work engagement (WE). Design/methodology/approach: The authors deployed a two-wave survey among 377 clerical...
job satisfaction Organizational Commitment Person–environment fit Work Engagement /dk/atira/pure/subjectarea/asjc/3200/3207 name=Social Psychology /dk/atira/pure/subjectarea/asjc/3200/3202 name=Applied Psychology /dk/atira/pure/subjectarea/asjc/1800/1803 name=Management Science and Operations Research /dk/atira/pure/subjectarea/asjc/1400/1407 name=Organizational Behavior and Human Resource Management
Outsourcing natural resource requirements within China.
Yaowen Zhang, Ling Shao, Xudong Sun, Mengyao Han, Xueli Zhao, Jing Meng, Bo Zhang, Han Qiao
Apr 12, 2019
Consumption demands are final drivers for the extraction and allocation of natural resources. This paper investigates demand-driven natural resource requirements and spatial outsourcing within China in 2012 by using the latest...
A novel and sensitive functional assay for complement Factor I based on the third proteolytic clip of C3b.
A sensitive assay for the functional activity of complement Factor I is described. This is based on its third proteolytic clip whereby Factor I cleaves cell-bound iC3b to cell-bound C3dg and soluble C3c, thereby abolishing...
Barriers to completing oral glucose tolerance testing in women at risk of gestational diabetes.
Functional expression of complement factor I following AAV-mediated gene delivery in the retina of mice and human cells.
Anna K Dreismann, Michelle E McClements, Alun R Barnard, Elise Orhan, Jane P Hughes, Peter J Lachmann, Robert E MacLaren
May 26, 2021
The in vivo expression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-ssDNA and anti-histone autoantibodies in a murine model of systemic lupus erythematosus.
Anthony P Manderson, Francesco Carlucci, Peter J Lachmann, Robert A Lazarus, Richard J Festenstein, H Terence Cook, Mark J Walport, Marina Botto
Jun 17, 2011
'Las partes donde Amor el cetro tiene'
PJ Lennon
Dec 21, 2015
Spreading the word
PJ Tracey
Apr 15, 2016
I examine the microlevel processes involved when members of an organization seek to persuade others to internalize a new institutional logic. To do so I conduct a qualitative study of the Alpha course, an evangelizing movement...
Book review
PJ Williamson
Aug 23, 2021
The title of this book, International Business Strategy, immediately begs the question: How does this differ from strategy in general? In the Introduction, the editors suggest several possibilities, including the need to operate...
Paratextual subversion
PJ Lennon
Dec 21, 2015
Wordsworth's 'Sonnets Dedicated to Liberty' and the British Revolutionary Past
PJ Connell
Jun 26, 2017
William Wordsworth's sonnets of 1802-3 offer an unusually rich insight into the poet's heightened political commitments during the short-lived Peace of Amiens and the subsequent resumption of hostilities with Napoleonic France....
English literature 1800-1899 Wordsworth William(1770-1850) 0000 0001 2127 8691 poetry "Sonnets Dedicated to Liberty" creativity republicanism Radicalism revolutionary politics French Revolution Burke Edmund(1729-1797) 0000 0001 2145 0834 Reflections on the Revolution in France(1790) Milton John(1608-1674) 0000 0001 2099 3562 Irish literature 1700-1799 prose 1600-1699
A calculus for flows in periodic domains
We present a constructive procedure for the calculation of 2-D potential
flows in periodic domains with multiple boundaries per period window. The
solution requires two steps: (i) a conformal mapping from a canonical...
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