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Fiction and Physicality
Rapid technological progression results in exciting new ways of interacting with our world whilst simultaneously limiting our experiences. Due to the pervasiveness of emerging technologies, designers are constantly faced with...
Fiction and Physicality
Rapid technological progression results in exciting new ways of interacting with our world whilst simultaneously limiting our experiences. Due to the pervasiveness of emerging technologies, designers are constantly faced with...
Profiting from innovation through cross-border market co-creation and co-opetition
We study the impact of the new intellectual property (IP) regime, as shaped by international agreements such as the Trade-Related-Aspects-of-IP-Rights (TRIPS), on the competitive positions of emerging country firms and advanced...
Handwriting with sound-speed imaging using ultrasound computed tomography.
This letter proposes the use of ultrasound computed tomography (USCT) for handwriting by imaging sound velocity changes in a medium caused by a rod. The rod was used as a writing object, and the tomographic instrument was able...
Profiting from innovation through cross-border market co-creation and co-opetition
We study the impact of the new intellectual property (IP) regime, as shaped by international agreements such as the Trade-Related-Aspects-of-IP-Rights (TRIPS), on the competitive positions of emerging country firms and advanced...
Social Media in Emergency Management
One of the main challenges of emergency management lies in communicating risks to the public. On some occasions, risk communicators might seek to increase awareness over emerging risks, while on others the aim might be to avoid...
A triple-modality ultrasound computed tomography based on full-waveform data for industrial processes
Ultrasound computed tomography (USCT) is gaining interests in many application areas in industrial processes. The recent scientific research focuses on the possible uses of USCT for varied fields of industry such as flow...
AA imaging TOF imaging Ultrasound computed tomography (USCT) full-waveform rich tomography industrial processes multi-modality ultrasound tomography reflection imaging ultrasound process tomography (UPT) /dk/atira/pure/subjectarea/asjc/3100/3105 name=Instrumentation /dk/atira/pure/subjectarea/asjc/2200/2208 name=Electrical and Electronic Engineering
Social Media in Emergency Management
One of the main challenges of emergency management lies in communicating risks to the public. On some occasions, risk communicators might seek to increase awareness over emerging risks, while on others the aim might be to avoid...
A triple-modality ultrasound computed tomography based on full-waveform data for industrial processes
Ultrasound computed tomography (USCT) is gaining interests in many application areas in industrial processes. The recent scientific research focuses on the possible uses of USCT for varied fields of industry such as flow...
AA imaging TOF imaging Ultrasound computed tomography (USCT) full-waveform rich tomography industrial processes multi-modality ultrasound tomography reflection imaging ultrasound process tomography (UPT) /dk/atira/pure/subjectarea/asjc/3100/3105 name=Instrumentation /dk/atira/pure/subjectarea/asjc/2200/2208 name=Electrical and Electronic Engineering
Handwriting with sound-speed imaging using ultrasound computed tomography.
This letter proposes the use of ultrasound computed tomography (USCT) for handwriting by imaging sound velocity changes in a medium caused by a rod. The rod was used as a writing object, and the tomographic instrument was able...
Towards Real-Time Control of a Semibatch Crystallization Process by Electrical and Ultrasound Tomographic Techniques
S. Aghajanian, G Rao, Panos Koulountzios, L Jackowska-Strumillo, Manuchehr Soleimani, T Koiranen
Jun 15, 2021
This research work presents a feasibility study to demonstrate the application of Electrical Resistance Tomography and transmission-based Ultrasound Computed Tomography for monitoring and control of micron-sized calcium...
Towards Real-Time Control of a Semibatch Crystallization Process by Electrical and Ultrasound Tomographic Techniques
S. Aghajanian, G Rao, Panos Koulountzios, L Jackowska-Strumillo, Manuchehr Soleimani, T Koiranen
Jun 15, 2021
This research work presents a feasibility study to demonstrate the application of Electrical Resistance Tomography and transmission-based Ultrasound Computed Tomography for monitoring and control of micron-sized calcium...
A framework of social media engagement
For organisations that interface with a large audience (i.e. governments, businesses, consumer bodies, non-profits), there are expectations that engagement on social media can improve responsiveness. The paper develops a...
A framework of social media engagement
For organisations that interface with a large audience (i.e. governments, businesses, consumer bodies, non-profits), there are expectations that engagement on social media can improve responsiveness. The paper develops a...
High-throughput analysis of candidate imprinted genes and allele-specific gene expression in the human term placenta.
Caroline Daelemans, Matthew E Ritchie, Guillaume Smits, Sayeda Abu-Amero, Ian M Sudbery, Matthew S Forrest, Susana Campino, Taane G Clark, Philip Stanier, Dominic Kwiatkowski, Panos Deloukas, Emmanouil T Dermitzakis, Simon Tavaré, Gudrun E Moore, Ian Dunham
Jun 14, 2011
Genetically modulated educational attainment and coronary disease risk.
Lingyao Zeng, Ioanna Ntalla, Thorsten Kessler, Adnan Kastrati, Jeanette Erdmann, UK Biobank CardioMetabolic Consortium CHD working group, John Danesh, Hugh Watkins, Nilesh J Samani, Panos Deloukas, Heribert Schunkert
May 03, 2019
Atherosclerosis Coronary Artery Disease Genetics genome-wide association studies School education Coronary Disease Educational Status Female Genetic Predisposition to Disease genetic variation Genome-Wide Association Study Humans Life Style Male Mendelian Randomization Analysis Polymorphism Single Nucleotide Risk Factors
Thyroid Function and Mood Disorders
Aleksander Kuś, Alisa D Kjaergaard, Eirini Marouli, Fabiola del Greco M, Rosalie BTM Sterenborg, Layal Chaker, Robin P Peeters, Tomasz Bednarczuk, Bjørn O Åsvold, Stephen Burgess, Panos Deloukas, Alexander Teumer, Christina Ellervik, Marco Medici
Apr 28, 2021
Background: Observational studies suggest that even minor variations in thyroid function are associated with the risk of mood disorders, including major depressive disorder (MDD) and bipolar disorder (BD). However, it is unknown...
Mendelian randomization study Bipolar Disorder Depression Mood Disorders normal-range thyroid function Thyroid Adult Bipolar Disorder Depressive Disorder Major Genome-Wide Association Study Humans Male Mendelian Randomization Analysis Mood Disorders risk Thyroid Function Tests Thyroid Gland Thyrotropin Thyroxine
Pathway-based subnetworks enable cross-disease biomarker discovery.
Syed Haider, Cindy Q Yao, Vicky S Sabine, Michal Grzadkowski, Vincent Stimper, Maud HW Starmans, Jianxin Wang, Francis Nguyen, Nathalie C Moon, Xihui Lin, Camilla Drake, Cheryl A Crozier, Cassandra L Brookes, Cornelis JH van de Velde, Annette Hasenburg, Dirk G Kieback, Christos J Markopoulos, Luc Y Dirix, Caroline Seynaeve, Daniel W Rea, Arek Kasprzyk, Philippe Lambin, Pietro Lio', John MS Bartlett, Paul C Boutros
May 13, 2019
Biomarkers lie at the heart of precision medicine. Surprisingly, while rapid genomic profiling is becoming ubiquitous, the development of biomarkers usually involves the application of bespoke techniques that cannot be directly...
Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes.
Kerrin S Small, Asa K Hedman, Elin Grundberg, Alexandra C Nica, Gudmar Thorleifsson, Augustine Kong, Unnur Thorsteindottir, So-Youn Shin, Hannah B Richards, GIANT Consortium, MAGIC Investigators, DIAGRAM Consortium, Nicole Soranzo, Kourosh R Ahmadi, Cecilia M Lindgren, Kari Stefansson, Emmanouil T Dermitzakis, Panos Deloukas, Timothy D Spector, Mark I McCarthy, MuTHER Consortium
Jun 11, 2018
Genome-wide association studies have identified many genetic variants associated with complex traits. However, at only a minority of loci have the molecular mechanisms mediating these associations been characterized. In...
Effects of Thyroid Function on Hemostasis, Coagulation, and Fibrinolysis
Christina Ellervik, Samia Mora, Aleksander Kuś, Bjørn Åsvold, Eirini Marouli, Panos Deloukas, Rosalie BTM Sterenborg, Alexander Teumer, Stephen Burgess, Maria Sabater-Lleal, Jennifer Huffman, Andrew D Johnson, David-Alexandre Trégouet, Nicolas L Smith, Marco Medici, Paul S DeVries, Daniel I Chasman, Alisa D Kjaergaard
Jul 26, 2021
Background: Untreated hypothyroidism is associated with acquired von Willebrand syndrome, and hyperthyroidism is associated with increased thrombosis risk. However, the causal effects of thyroid function on hemostasis...
Coagulation Fibrinolysis Hemostasis hyperthyroidism Hypothyroidism thyroid hormone thyroid peroxidase antibody Thyrotropin Autoantibodies Biomarkers Blood Coagulation Blood Coagulation Factors Blood Coagulation Tests Case-Control Studies Fibrinolysis Genetic Predisposition to Disease Genome-Wide Association Study Hemostasis Humans hyperthyroidism Hypothyroidism Mendelian Randomization Analysis Phenotype Polymorphism Single Nucleotide Risk Assessment Risk Factors Thyrotropin Thyroxine von Willebrand factor
Novel loci associated with increased risk of sudden cardiac death in the context of coronary artery disease.
Adriana Huertas-Vazquez, Christopher P Nelson, Xiuqing Guo, Kyndaron Reinier, Audrey Uy-Evanado, Carmen Teodorescu, Jo Ayala, Katherine Jerger, Harpriya Chugh, WTCCC+, Peter S Braund, Panos Deloukas, Alistair S Hall, Anthony J Balmforth, Michelle Jones, Kent D Taylor, Sara L Pulit, Christopher Newton-Cheh, Karen Gunson, Jonathan Jui, Jerome I Rotter, Christine M Albert, Nilesh J Samani, Sumeet S Chugh
Nov 17, 2017
BACKGROUND: Recent genome-wide association studies (GWAS) have identified novel loci associated with sudden cardiac death (SCD). Despite this progress, identified DNA variants account for a relatively small portion of overall...
Novel genetic loci associated with long-term deterioration in blood lipid concentrations and coronary artery disease in European adults.
Tibor V Varga, Azra Kurbasic, Mattias Aine, Pontus Eriksson, Ashfaq Ali, George Hindy, Stefan Gustafsson, Jian'an Luan, Dmitry Shungin, Yan Chen, Christina-Alexandra Schulz, Peter M Nilsson, Göran Hallmans, Inês Barroso, Panos Deloukas, Claudia Langenberg, Robert A Scott, Nicholas J Wareham, Lars Lind, Erik Ingelsson, Olle Melander, Marju Orho-Melander, Frida Renström, Paul W Franks
Aug 15, 2017
BACKGROUND: Cross-sectional genome-wide association studies have identified hundreds of loci associated with blood lipids and related cardiovascular traits, but few genetic association studies have focused on long-term changes...
Prospective cohort study Genetic epidemiology longitudinal analysis Morbidity single nucleotide polymorphism Total cholesterol Triglycerides Adult Aged Coronary Artery Disease Cross-Sectional Studies Female Genetic Loci Genome-Wide Association Study Genotype Humans Lipids Male Meta-Analysis as Topic Middle Aged Polymorphism Single Nucleotide Prospective Studies Sweden White People
Big data from electronic health records for early and late translational cardiovascular research
Harry Hemingway, Folkert W Asselbergs, John Danesh, Richard Dobson, Nikolaos Maniadakis, Aldo Maggioni, Ghislaine JM van Thiel, Maureen Cronin, Gunnar Brobert, Panos Vardas, Stefan D Anker, Diederick E Grobbee, Spiros Denaxas, Big Data for Better Outcomes, BigData@Heart Consortium of 20 academic and industry partners including ESC Innovative Medicines Initiative 2nd programme
Jul 30, 2018
AIMS: Cohorts of millions of people's health records, whole genome sequencing, imaging, sensor, societal and publicly available data present a rapidly expanding digital trace of health. We aimed to critically review, for the...
Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants.
Fiona Allum, Xiaojian Shao, Frédéric Guénard, Marie-Michelle Simon, Stephan Busche, Maxime Caron, John Lambourne, Julie Lessard, Karolina Tandre, Åsa K Hedman, Tony Kwan, Bing Ge, Multiple Tissue Human Expression Resource Consortium, Lars Rönnblom, Mark I McCarthy, Panos Deloukas, Todd Richmond, Daniel Burgess, Timothy D Spector, André Tchernof, Simon Marceau, Mark Lathrop, Marie-Claude Vohl, Tomi Pastinen, Elin Grundberg
Aug 04, 2015
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