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Fifty important research questions in microbial ecology.
Rachael E Antwis, Sarah M Griffiths, Xavier A Harrison, Paz Aranega-Bou, Andres Arce, Aimee S Bettridge, Francesca L Brailsford, Alexandre de Menezes, Andrew Devaynes, Kristian M Forbes, Ellen L Fry, Ian Goodhead, Erin Haskell, Chloe Heys, Chloe James, Sarah R Johnston, Gillian R Lewis, Zenobia Lewis, Michael C Macey, Alan McCarthy, James E McDonald, Nasmille L Mejia-Florez, David O'Brien, Chloé Orland, Marco Pautasso, William DK Reid, Heather A Robinson, Kenneth Wilson, William J Sutherland
May 13, 2019
Longitudinal effects of clozapine concentration and clozapine to N-desmethylclozapine ratio on cognition
Francesco Dal Santo, Isaac Jarratt-Barnham, Leticia González-Blanco, María Paz García-Portilla, Julio Bobes, Emilio Fernández-Egea
Jan 28, 2020
Co-delivery of buparvaquone and polymyxin B in a nanostructured lipid carrier for leishmaniasis treatment
L.M Monteiro, Raimar Löbenberg, Nikoletta Fotaki, Gabriel Lima Barros de Araujo, P.C Cotrim, Nádia Araci Bou-Chacra
Sep 01, 2019
Objectives: This study aimed to describe the preparation and in vitro evaluation of a surface-modified nanostructured lipid carrier (NLC) using chitosan and dextran for co-delivery of buparvaquone (BPQ) and polymyxin B (PB)...
Buparvaquone Chitosan Dextran Leishmaniasis Nanostructured lipid carrier Polymyxin B /dk/atira/pure/subjectarea/asjc/2400/2404 name=Microbiology /dk/atira/pure/subjectarea/asjc/2700/2723 name=Immunology and Allergy /dk/atira/pure/subjectarea/asjc/2400/2403 name=Immunology /dk/atira/pure/subjectarea/asjc/2700/2726 name=Microbiology (medical)
Determination of the molecular diffusion coefficients in ternary mixtures by the sliding symmetric tubes technique
A new analytical methodology has been developed to determine the diagonal and cross-diagonal molecular diffusion coefficients in ternary mixtures by the Sliding Symmetric Tubes technique. The analytical solution is tested in...
Determination of the molecular diffusion coefficients in ternary mixtures by the sliding symmetric tubes technique
A new analytical methodology has been developed to determine the diagonal and cross-diagonal molecular diffusion coefficients in ternary mixtures by the Sliding Symmetric Tubes technique. The analytical solution is tested in...
Anisotropic growth is achieved through the additive mechanical effect of material anisotropy and elastic asymmetry.
Firas Bou Daher, Yuanjie Chen, Behruz Bozorg, Jack Clough, Henrik Jönsson, Siobhan A Braybrook
Nov 22, 2018
Fast directional growth is a necessity for the young seedling; after germination, it needs to quickly penetrate the soil to begin its autotrophic life. In most dicot plants, this rapid escape is due to the anisotropic elongation...
Co-delivery of buparvaquone and polymyxin B in a nanostructured lipid carrier for leishmaniasis treatment
L.M Monteiro, Raimar Löbenberg, Nikoletta Fotaki, Gabriel Lima Barros de Araujo, P.C Cotrim, Nádia Araci Bou-Chacra
Sep 01, 2019
Objectives: This study aimed to describe the preparation and in vitro evaluation of a surface-modified nanostructured lipid carrier (NLC) using chitosan and dextran for co-delivery of buparvaquone (BPQ) and polymyxin B (PB)...
Buparvaquone Chitosan Dextran Leishmaniasis Nanostructured lipid carrier Polymyxin B /dk/atira/pure/subjectarea/asjc/2400/2404 name=Microbiology /dk/atira/pure/subjectarea/asjc/2700/2723 name=Immunology and Allergy /dk/atira/pure/subjectarea/asjc/2400/2403 name=Immunology /dk/atira/pure/subjectarea/asjc/2700/2726 name=Microbiology (medical)
Systematic structural studies on cobalt(II) complexes of tricyclohexylphosphine oxide and related ligands
R Bou-Moreno, S A Cotton, V Hunter, K Leonard, A W G Platt, Paul R Raithby, Stefanie Schiffers
Nov 03, 2011
The new cobalt(II) phosphine oxide complexes Co(Cy(3)PO)(2)Cl(2) (1), Co(Cy(3)PO)(2)Br(2) (2), Co(Cy(3)PO)(2)I(2) (3), Co(Ph(2)CyPO)(2)Cl(2) (4), Co(Ph(2)CyPO)(2)Br(2) (5), Co(Ph(2)CyPO)(2)I(2) (6), Co(Ph(2)EtPO)(2)Br(2) (7)...
Contribution to the benchmark for ternary mixtures
Miren Larrañaga, M. Mounir Bou-Ali, David Alonso de Mezquıa, D. Andrew S Rees, Jose Antonio Madariaga, Carlos Santamaría, Jean K. Platten
Apr 01, 2015
This work is part of an international project for the research on the transport properties in ternary mixtures. Six different teams have analysed the same mixture by independent techniques in order to compare the results and...
Systematic structural studies on cobalt(II) complexes of tricyclohexylphosphine oxide and related ligands
R Bou-Moreno, S A Cotton, V Hunter, K Leonard, A W G Platt, Paul R Raithby, Stefanie Schiffers
Nov 03, 2011
The new cobalt(II) phosphine oxide complexes Co(Cy(3)PO)(2)Cl(2) (1), Co(Cy(3)PO)(2)Br(2) (2), Co(Cy(3)PO)(2)I(2) (3), Co(Ph(2)CyPO)(2)Cl(2) (4), Co(Ph(2)CyPO)(2)Br(2) (5), Co(Ph(2)CyPO)(2)I(2) (6), Co(Ph(2)EtPO)(2)Br(2) (7)...
Contribution to the benchmark for ternary mixtures
Miren Larrañaga, M. Mounir Bou-Ali, David Alonso de Mezquıa, D. Andrew S Rees, Jose Antonio Madariaga, Carlos Santamaría, Jean K. Platten
Apr 01, 2015
This work is part of an international project for the research on the transport properties in ternary mixtures. Six different teams have analysed the same mixture by independent techniques in order to compare the results and...
Extracting in Situ Charge Carrier Diffusion Parameters in Perovskite Solar Cells with Light Modulated Techniques.
Agustín Bou, Haralds A Boliņš, Arjun Ashoka, Héctor Cruanyes, Antonio Guerrero, Felix Deschler, Juan Bisquert
Jan 07, 2022
Frequency resolved methods are widely used to determine device properties of perovskite solar cells. However, obtaining the electronic parameters for diffusion and recombination by impedance spectroscopy has been so far elusive...
Influence of secondary sources in the Brief Negative Symptom Scale.
Devi Treen, George Savulich, Gisela Mezquida, Maria Paz García-Portilla, Alba Toll, Clemente García-Rizo, Leticia García-Álvarez, Daniel Bergé, Julio Bobes, Miguel bernardo, Emilio Fernandez-Egea, Anna Mané
Nov 23, 2018
Highly Water-Soluble Orotic Acid Nanocrystals Produced by High-Energy Milling
Jéssica de Cássia Zaghi Compri, Veni Maria Andres Felli, Felipe Rebello Lourenço, Takayuki Takatsuka, Nikoletta Fotaki, Raimar Löbenberg, Nádia Araci Bou-Chacra, Gabriel Lima Barros de Araujo
May 01, 2019
Orotic acid (OA), a heterocyclic compound also known as vitamin B13, has shown potent antimalarial and cardiac protection activities; however, its limited water solubility has posed a barrier to its use in therapeutic...
A transposable element insertion is associated with an alternative life history strategy.
Alyssa Woronik, Kalle Tunström, Michael W Perry, Ramprasad Neethiraj, Constanti Stefanescu, Maria de la Paz Celorio-Mancera, Oskar Brattström, Jason Hill, Philipp Lehmann, Reijo Käkelä, Christopher W Wheat
Dec 22, 2020
Animals Butterflies CRISPR-Cas Systems Color DNA Transposable Elements Female Gene Editing Gene Expression Profiling Gene Expression Regulation Developmental Genetic Loci Homeodomain Proteins Life History Traits Male Pigmentation Pigments Biological Reproduction Sex Factors whole genome sequencing Wings Animal
Obstetric Phenotypes in the Heterogeneity of Schizophrenia.
Gisela Mezquida, Emilio Fernandez-Egea, Devi Treen, Anna Mané, Daniel Bergé, George Savulich, Leticia Garcia-Alvarez, Paz García-Portilla, Julio Bobes, Miguel bernardo, Clemente Garcia-Rizo
Dec 03, 2018
Highly Water-Soluble Orotic Acid Nanocrystals Produced by High-Energy Milling
Jéssica de Cássia Zaghi Compri, Veni Maria Andres Felli, Felipe Rebello Lourenço, Takayuki Takatsuka, Nikoletta Fotaki, Raimar Löbenberg, Nádia Araci Bou-Chacra, Gabriel Lima Barros de Araujo
May 01, 2019
Orotic acid (OA), a heterocyclic compound also known as vitamin B13, has shown potent antimalarial and cardiac protection activities; however, its limited water solubility has posed a barrier to its use in therapeutic...
A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns.
Wei Jiao, Gurnit Atwal, Paz Polak, Rosa Karlic, Edwin Cuppen, PCAWG Tumor Subtypes and Clinical Translation Working Group, Alexandra Danyi, Jeroen de Ridder, Carla van Herpen, Martijn P Lolkema, Neeltje Steeghs, Gad Getz, Quaid D Morris, Lincoln D Stein, PCAWG Consortium
May 14, 2020
In cancer, the primary tumour's organ of origin and histopathology are the strongest determinants of its clinical behaviour, but in 3% of cases a patient presents with a metastatic tumour and no obvious primary. Here, as part of...
A transposable element insertion is associated with an alternative life history strategy.
Alyssa Woronik, Kalle Tunström, Michael W Perry, Ramprasad Neethiraj, Constanti Stefanescu, Maria de la Paz Celorio-Mancera, Oskar Brattström, Jason Hill, Philipp Lehmann, Reijo Käkelä, Christopher W Wheat
Jan 27, 2020
Tradeoffs affect resource allocation during development and result in fitness consequences that drive the evolution of life history strategies. Yet despite their importance, we know little about the mechanisms underlying life...
The effect of early life events on glucose levels in first-episode psychosis.
Clemente Garcia-Rizo, Bibiana Cabrera, Miquel Bioque, Gisela Mezquida, Antonio Lobo, Ana Gonzalez-Pinto, Covadonga M Diaz-Caneja, Iluminada Corripio, Eduard Vieta, Inmaculada Baeza, Maria Paz Garcia-Portilla, Miguel Gutierrez-Fraile, Roberto Rodriguez-Jimenez, Marina Garriga, Emilio Fernandez-Egea, Miguel bernardo, PEPs GROUP
Dec 19, 2022
A new medium-throughput screening design approach for the development of hydroxymethylnitrofurazone (NFOH) nanostructured lipid carrier for treating leishmaniasis
Aline de Souza, Megumi Nishitani Yukuyama, Eduardo José Barbosa, Lis Marie Monteiro, Ana Cristina Breithaupt Faloppa, Leandro Augusto Calixto, Gabriel Lima de Barros Araújo, Nikoletta Fotaki, Raimar Löbenberg, Nádia Araci Bou-Chacra
Sep 01, 2020
Hydroxymethilnitrofurazone (NFOH) is a nitrofurazone derivative and has potential use in treating leishmaniasis. However, due to low water solubility and bioavailability, NFOH has failed in in vivo tests. Nanostructured lipid...
Drug delivery system(s) Hydroxymethylnitrofurazone Leishmaniasis Lipid-based formulation(s) Nanoparticle(s) Nanostructured lipid carrier /dk/atira/pure/subjectarea/asjc/1300/1305 name=Biotechnology /dk/atira/pure/subjectarea/asjc/3100/3110 name=Surfaces and Interfaces /dk/atira/pure/subjectarea/asjc/1600/1606 name=Physical and Theoretical Chemistry /dk/atira/pure/subjectarea/asjc/1500/1505 name=Colloid and Surface Chemistry
A new medium-throughput screening design approach for the development of hydroxymethylnitrofurazone (NFOH) nanostructured lipid carrier for treating leishmaniasis
Aline de Souza, Megumi Nishitani Yukuyama, Eduardo José Barbosa, Lis Marie Monteiro, Ana Cristina Breithaupt Faloppa, Leandro Augusto Calixto, Gabriel Lima de Barros Araújo, Nikoletta Fotaki, Raimar Löbenberg, Nádia Araci Bou-Chacra
Sep 01, 2020
Hydroxymethilnitrofurazone (NFOH) is a nitrofurazone derivative and has potential use in treating leishmaniasis. However, due to low water solubility and bioavailability, NFOH has failed in in vivo tests. Nanostructured lipid...
Drug delivery system(s) Hydroxymethylnitrofurazone Leishmaniasis Lipid-based formulation(s) Nanoparticle(s) Nanostructured lipid carrier /dk/atira/pure/subjectarea/asjc/1300/1305 name=Biotechnology /dk/atira/pure/subjectarea/asjc/3100/3110 name=Surfaces and Interfaces /dk/atira/pure/subjectarea/asjc/1600/1606 name=Physical and Theoretical Chemistry /dk/atira/pure/subjectarea/asjc/1500/1505 name=Colloid and Surface Chemistry
Estimating the Potential for Conservation and Farming in the Amazon and Cerrado under Four Policy Scenarios
Since 2013, clearing rates have rapidly increased in the Amazon and Cerrado biomes. This acceleration has raised questions about the efficacy of current regional public and private conservation policies that seek to...
Amintas Brandão Jr., Lisa Rausch, América Paz Durán, Ciniro Costa Jr., Seth A Spawn, Holly K Gibbs
Feb 11, 2020
SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development.
Ivy Kim-Ni Chiang, Martin Fritzsche, Cathy Pichol-Thievend, Alice Neal, Kelly Holmes, Anne Lagendijk, Jeroen Overman, Donatella D'Angelo, Alice Omini, Dorien Hermkens, Emmanuelle Lesieur, Ke Liu, Indrika Ratnayaka, Monica Corada, George Bou-Gharios, Jason Carroll, Elisabetta Dejana, Stefan Schulte-Merker, Benjamin Hogan, Monica Beltrame, Sarah De Val, Mathias Francois
Apr 17, 2019
Arterial enhancer artery Endothelial Cell human MOUSE Notch1 SoxF Transcriptional regulation Zebrafish Amino Acid Sequence Animals Animals Genetically Modified arteries Arteriovenous Malformations Enhancer Elements Genetic Female Gene Expression Regulation Developmental Human Umbilical Vein Endothelial Cells Humans Male Mice Mice Inbred C57BL Mice Knockout Mice Transgenic Pregnancy Receptor Notch1 SOXF Transcription Factors Sequence Homology Amino Acid Signal Transduction Zebrafish Zebrafish Proteins
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