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Results: 2689
HLA class I and II expression in oropharyngeal squamous cell carcinoma in relation to tumor HPV status and clinical outcome.
Anders Näsman, Emilia Andersson, Linda Marklund, Nikolaos Tertipis, Lalle Hammarstedt-Nordenvall, Per Attner, Tommy Nyberg, Giuseppe V Masucci, Eva Munck-Wikland, Torbjörn Ramqvist, Tina Dalianis
Jun 08, 2018
HPV-DNA positive (HPVDNA+) oropharyngeal squamous cell carcinoma (OSCC) has better clinical outcome than HPV-DNA negative (HPVDNA-) OSCC. Current treatment may be unnecessarily extensive for most HPV+ OSCC, but before...
Adult Aged Aged 80 and over Carcinoma Squamous Cell Cohort Studies Cyclin-Dependent Kinase Inhibitor p16 DNA Viral Female Gene Expression Regulation Neoplastic HLA Antigens Histocompatibility Antigens Class I Histocompatibility Antigens Class II Humans Male Middle Aged Oropharyngeal Neoplasms Papillomaviridae Prognosis Survival Analysis Treatment Outcome
Alternatives to Traditional Per-Oral Endoscopy for Screening.
Barrett's esophagus (BE) predisposes patients to esophageal adenocarcinoma. 3 to 6% of individuals with gastro-esophageal reflux disease are estimated to have BE but only 20 to 25% of BE patients are currently diagnosed. The...
Delicate seafloor landforms reveal past Antarctic grounding-line retreat of kilometers per year.
JA Dowdeswell, CL Batchelor, A Montelli, D Ottesen, FDW Christie, EK Dowdeswell, J Evans
Jun 04, 2020
A suite of grounding-line landforms on the Antarctic seafloor, imaged at submeter horizontal resolution from an autonomous underwater vehicle, enables calculation of ice sheet retreat rates from a complex of grounding-zone...
Associating the Change in New COVID-19 Cases to GDP per Capita in 38 European Countries in the First Wave of the Pandemic.
COVID-19 has affected all countries globally. We explore associations between the change in new COVID-19 registered cases per million population and various macroeconomic and well-being indicators in 38 European countries over a...
The Municipality's Role in a Smart Internet of Things Ecosystem
This article explores how municipalities plan and utilize Internet of Things (IoT) for smart city development, as well as how they collaborate with actors in the IoT-ecosystem. To do so, in-depth interviews and secondary...
Published by: IGI Global Scientific Publishing
Organomegaly in Mali before and after praziquantel treatment. A possible association with Schistosoma haematobium.
Chalotte Willemann Stecher, Henry Madsen, Shona Wilson, Moussa Sacko, Christian Wejse, Adama D Keita, Aly Landouré, Mamadou S Traoré, Per Kallestrup, Eskild Petersen, Birgitte Vennervald
Jan 24, 2018
Continuous exposure to schistosome-infested water results in acute and chronic morbidity in all ages. We analysed occurence of organomegaly via ultrasonography and investigated a possible additive effect of dual-dose drug...
Intelligent Anti-Jamming Decision Algorithm of Bivariate Frequency Hopping Pattern Based on DQN With PER and Pareto
To improve the anti-jamming performance of frequency hopping system in complex electromagnetic environment, a Deep Q-Network algorithm with priority experience replay (PER) based on Pareto samples (PPER-DQN) is proposed, which...
Published by: IGI Global Scientific Publishing
Overexpression of the WAPO-A1 gene increases the number of spikelets per spike in bread wheat.
Lukas M Wittern, Jose M Barrero, William D Bovill, Klara L Verbyla, Trijntje Hughes, Steve M Swain, Gareth Steed, Alex AR Webb, Keith Gardner, Andy Greenland, John Jacobs, Claus Frohberg, Ralf-Christian Schmidt, Colin Cavanagh, Antje Rohde, Mark W Davey, Matthew A Hannah
Sep 20, 2022
Two homoeologous QTLs for number of spikelets per spike (SPS) were mapped on chromosomes 7AL and 7BL using two wheat MAGIC populations. Sets of lines contrasting for the QTL on 7AL were developed which allowed for the validation...
A synthetic enzyme built from DNA flips 107 lipids per second in biological membranes.
Alexander Ohmann, Chen-Yu Li, Christopher Maffeo, Kareem Al Nahas, Kevin N Baumann, Kerstin Göpfrich, Jejoong Yoo, Ulrich F Keyser, Aleksei Aksimentiev
Sep 10, 2018
Mimicking enzyme function and increasing performance of naturally evolved proteins is one of the most challenging and intriguing aims of nanoscience. Here, we employ DNA nanotechnology to design a synthetic enzyme that...
A Mendelian randomization analysis of circulating lipid traits and breast cancer risk.
Alicia Beeghly-Fadiel, Nikhil K Khankari, Ryan J Delahanty, Xiao-Ou Shu, Yingchang Lu, Marjanka K Schmidt, Manjeet K Bolla, Kyriaki Michailidou, Qin Wang, Joe Dennis, Drakoulis Yannoukakos, Alison M Dunning, Paul DP Pharoah, Georgia Chenevix-Trench, Roger L Milne, David J Hunter, Hall Per, Peter Kraft, Jacques Simard, Douglas F Easton, Wei Zheng
Jan 29, 2020
BACKGROUND: Conventional epidemiologic studies have evaluated associations between circulating lipid levels and breast cancer risk, but results have been inconsistent. As Mendelian randomization analyses may provide evidence for...
Proteinase-3 and myeloperoxidase serotype in relation to demographic factors and geographic distribution in anti-neutrophil cytoplasmic antibody-associated glomerulonephritis.
Maria Weiner, Rune Bjørneklett, Zdenka Hrušková, Bruce Mackinnon, Caroline J Poulton, Leo Sindelar, Aladdin J Mohammad, Per Eriksson, Loreto Gesualdo, Duvuru Geetha, Matija Crnogorac, David Jayne, Susan L Hogan, Colin Geddes, Vladimir Tesar, Knut Aasarød, Mårten Segelmark
May 13, 2019
BACKGROUND: In anti-neutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis, antigen specificity varies between myeloperoxidase (MPO) and proteinase 3 (PR3). This has been reported to vary in relation to age...
Aged Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Antibodies Antineutrophil Cytoplasmic Antibody Specificity Biopsy Czech Republic Demography Female Geography glomerulonephritis Humans Italy Male Middle Aged Myeloblastin Norway Peroxidase Registries Serogroup Sweden United Kingdom United States
The smallest known Devonian tetrapod shows unexpectedly derived features.
A new genus and species of Devonian tetrapod, Brittagnathus minutus gen. et sp. nov., is described from a single complete right lower jaw ramus recovered from the Acanthostega mass-death deposit in the upper part of the Britta...
Volumetric mammographic density
Judith S Brand, Keith Humphreys, Deborah J Thompson, Jingmei Li, Mikael Eriksson, Per Hall, Kamila Czene, , Per Hall
Feb 12, 2015
An exploration into measurement consistency on coordinate measuring machines
In high precision industry, the measurement of geometry is often performed using coordinate measuring machines (CMMs). Measurements on CMMs can occur at many places within a long and global supply chain. In this context it is...
An exploration into measurement consistency on coordinate measuring machines
In high precision industry, the measurement of geometry is often performed using coordinate measuring machines (CMMs). Measurements on CMMs can occur at many places within a long and global supply chain. In this context it is...
IR Tools
This paper describes a new MATLAB software package of iterative regularization methods and test problems for large-scale linear inverse problems. The software package, called IR TOOLS, serves two related purposes: we provide...
Mammographic density change in a cohort of premenopausal women receiving tamoxifen for breast cancer prevention over 5 years
Adam R. Brentnall, Ruth Warren, Elaine F. Harkness, Susan M. Astley, Julia Wiseman, Jill Fox, Lynne Fox, Mikael Eriksson, Per Hall, Jack Cuzick, D. Gareth Evans, Anthony Howell
Sep 29, 2020
Abstract: Background: A decrease in breast density due to tamoxifen preventive therapy might indicate greater benefit from the drug. It is not known whether mammographic density continues to decline after 1 year of therapy, or...
A Review of the Segmental Diameter of the Healthy Human Spinal Cord.
Knowledge of the average size and variability of the human spinal cord can be of importance when treating pathological conditions in the spinal cord. Data on healthy human spinal cord morphometrics have been published for more...
Complex Interaction as Emergent Behaviour
Accurately modelling user behaviour has the potential to significantly improve the quality of human-computer interaction. Traditionally, these models are carefully hand-crafted to approximate specific aspects of well-documented...
Mammographic density change in a cohort of premenopausal women receiving tamoxifen for breast cancer prevention over 5 years.
Adam R Brentnall, Ruth Warren, Elaine F Harkness, Susan M Astley, Julia Wiseman, Jill Fox, Lynne Fox, Mikael Eriksson, Per Hall, Jack Cuzick, D Gareth Evans, Anthony Howell
Oct 01, 2021
BACKGROUND: A decrease in breast density due to tamoxifen preventive therapy might indicate greater benefit from the drug. It is not known whether mammographic density continues to decline after 1 year of therapy, or whether...
The Office of the Future
Virtual reality has the potential to change the way we work. We envision the future office worker to be able to work productively everywhere solely using portable standard input devices and immersive head-mounted displays....
Mammographic density change in a cohort of premenopausal women receiving tamoxifen for breast cancer prevention over 5 years
Adam R. Brentnall, Ruth Warren, Elaine F. Harkness, Susan M. Astley, Julia Wiseman, Jill Fox, Lynne Fox, Mikael Eriksson, Per Hall, Jack Cuzick, D. Gareth Evans, Anthony Howell
Oct 12, 2020
Abstract: Background: A decrease in breast density due to tamoxifen preventive therapy might indicate greater benefit from the drug. It is not known whether mammographic density continues to decline after 1 year of therapy, or...
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