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Results: 261
Genetic Risk as a Marker of Amyloid-β and Tau Burden in Cerebrospinal Fluid.
Nicola Voyle, Hamel Patel, Amos Folarin, Stephen Newhouse, Caroline Johnston, Pieter Jelle Visser, Richard JB Dobson, Steven J Kiddle, EDAR and DESCRIPA study groups and the Alzheimer’s Disease Neuroimaging Initiative
May 21, 2018
Alzheimer’s disease biomarker Blood multi-modal polygenic risk score Tau Aged Aged 80 and over Alzheimer Disease Amyloid beta-Peptides Apolipoproteins E Biomarkers Cohort Studies Databases Factual Early Diagnosis Female Humans Logistic Models Male Oligonucleotide Array Sequence Analysis Polymorphism Single Nucleotide Positron-Emission Tomography tau Proteins
Amyloid-β and APOE genotype predict memory decline in cognitively unimpaired older individuals independently of Alzheimer's disease polygenic risk score.
Jori Tomassen, Anouk den Braber, Sven J van der Lee, Lianne M Reus, Elles Konijnenberg, Stephen F Carter, Maqsood Yaqub, Bart NM van Berckel, Lyduine E Collij, Dorret I Boomsma, Eco JC de Geus, Philip Scheltens, Karl Herholz, Betty M Tijms, Pieter Jelle Visser
Dec 15, 2022
BACKGROUND: What combination of risk factors for Alzheimer's disease (AD) are most predictive of cognitive decline in cognitively unimpaired individuals remains largely unclear. We studied associations between APOE genotype...
APOE genotype Amyloid-β cognitive decline Longitudinal design neuropsychology polygenic risk score Preclinical Alzheimer’s disease Female Humans Male Alzheimer Disease Amyloid beta-Peptides Cognitive Dysfunction Genotype Apolipoproteins E Memory Disorders Risk Factors Positron-Emission Tomography Apolipoprotein E4
The Grizzly, March 17, 1989
Kevin Murphy, Todd Koser, Richard P. Richter, Yvette Dennis, Veronica Algeo, Neil Schafer, Bridget Algeo, Lora L. Hart, Katherine Grim, Matt Becker, Christopher Harbach, Peggy Hermann, Derk Visser, Lisa Tremper Barnes
Jan 01, 0001
Pledging Violations Abound: Change Imminent Approaching Commencement Scares Seniors Letters: Bermans Ship Garbage Here?; Alumni Concerned About Curtis Fire; Bond Facts Straight?; Collegeville Water Now Non-Toxic; Visser Vicous...
Ursinus College Collegeville Pennsylvania newspaper Sara Ward Shannon Peru wrestling Basketball track team Biloxi Blues Colonial restaurant Easton Campus Activities Board honor code Julian Bond Waste disposal pollution EPA Water Authority arson pledging fraternities career planning cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The Grizzly, April 15, 1988
Jean M. Kiss, Lora L. Hart, Veronica Algeo, Tony Tarone, Ed Wentzel, Andrea Power, Peter Henty, Bill Platt, Steve Gall, Kerry Durgin, Karen Singhofen, Derk Visser, Richard P. Richter, Douglas Nagy
Jan 01, 0001
Greek Week's Coming! Sorority Songfest Sunday Letters: Visser to Goofley: Kiss Dirt!; Code: Honor; Billing Miffs Student; Professor Nagy Responds to Tiryak Forum; Red Cross Congratulates UC Donators Mid East Forum Scheduled ...
Ursinus College Collegeville Pennsylvania newspaper Student Alumni Association Alysa Vickery Rumblers Kris Carr Susan Stamburg baseball softball Mark Hallinger cycling team sailing team white water rafting track team lacrosse Gad Gilbar Edmund Tiryak Abortion Diversity Inter Fraternity Council Inter Sorority Council cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Prescreening for European Prevention of Alzheimer Dementia (EPAD) trial-ready cohort
Lisa Vermunt, Graciela Muniz-Terrera, Lea ter Meulen, Colin Veal, Kaj Blennow, Archie Campbell, Isabelle Carrié, Julien Delrieu, Karine Fauria, Gema Huesa Rodríguez, Silvia Ingala, Natalie Jenkins, José Luis Molinuevo, Pierre-Jean Ousset, David Porteous, Niels D Prins, Alina Solomon, Brian D Tom, Henrik Zetterberg, Marissa Zwan, Craig W Ritchie, Philip Scheltens, Gerald Luscan, Anthony J Brookes, Pieter Jelle Visser
Feb 07, 2020
BACKGROUND:Recruitment is often a bottleneck in secondary prevention trials in Alzheimer disease (AD). Furthermore, screen-failure rates in these trials are typically high due to relatively low prevalence of AD pathology in...
Amyloid Recruitment engagement Registries Secondary prevention trials Prescreening Trial-ready cohort
Published by: Alzheimer's research & therapy
Prescreening for European Prevention of Alzheimer Dementia (EPAD) trial-ready cohort
Lisa Vermunt, Graciela Muniz-Terrera, Lea ter Meulen, Colin Veal, Kaj Blennow, Archie Campbell, Isabelle Carrié, Julien Delrieu, Karine Fauria, Gema Huesa Rodríguez, Silvia Ingala, Natalie Jenkins, José Luis Molinuevo, Pierre-Jean Ousset, David Porteous, Niels D Prins, Alina Solomon, Brian D Tom, Henrik Zetterberg, Marissa Zwan, Craig W Ritchie, Philip Scheltens, Gerald Luscan, Anthony J Brookes, Pieter Jelle Visser, IMI-EPAD collaborators
Jan 20, 2020
BACKGROUND: Recruitment is often a bottleneck in secondary prevention trials in Alzheimer disease (AD). Furthermore, screen-failure rates in these trials are typically high due to relatively low prevalence of AD pathology in...
Prescreening for European Prevention of Alzheimer Dementia (EPAD) trial-ready cohort
Lisa Vermunt, Graciela Muniz-Terrera, Lea ter Meulen, Colin Veal, Kaj Blennow, Archie Campbell, Isabelle Carrié, Julien Delrieu, Karine Fauria, Gema Huesa Rodríguez, Silvia Ingala, Natalie Jenkins, José Luis Molinuevo, Pierre-Jean Ousset, David Porteous, Niels D. Prins, Alina Solomon, Brian D. Tom, Henrik Zetterberg, Marissa Zwan, Craig W. Ritchie, Philip Scheltens, Gerald Luscan, Anthony J. Brookes, Pieter Jelle Visser
Jun 06, 2020
Abstract: Background: Recruitment is often a bottleneck in secondary prevention trials in Alzheimer disease (AD). Furthermore, screen-failure rates in these trials are typically high due to relatively low prevalence of AD...
Prescreening for European Prevention of Alzheimer Dementia (EPAD) trial-ready cohort
Lisa Vermunt, Graciela Muniz-Terrera, Lea ter Meulen, Colin Veal, Kaj Blennow, Archie Campbell, Isabelle Carrié, Julien Delrieu, Karine Fauria, Gema Huesa Rodríguez, Silvia Ingala, Natalie Jenkins, José Luis Molinuevo, Pierre-Jean Ousset, David Porteous, Niels D. Prins, Alina Solomon, Brian D. Tom, Henrik Zetterberg, Marissa Zwan, Craig W. Ritchie, Philip Scheltens, Gerald Luscan, Anthony J. Brookes, Pieter Jelle Visser
Jan 05, 2021
Abstract: Background: Recruitment is often a bottleneck in secondary prevention trials in Alzheimer disease (AD). Furthermore, screen-failure rates in these trials are typically high due to relatively low prevalence of AD...
The minus sign in the first law of de Sitter horizons
Abstract
Due to a well-known, but curious, minus sign in the Gibbons-Hawking first law for the static patch of de Sitter space, the entropy of the...
Role of Leucine 341 in Thyroid Hormone Receptor Beta Revealed by a Novel Mutation Causing Thyroid Hormone Resistance.
Karn Wejaphikul, Stefan Groeneweg, Prapai Dejkhamron, Kevalee Unachak, W Edward Visser, V Krishna Chatterjee, Theo J Visser, Marcel E Meima, Robin P Peeters
May 03, 2019
Leucine 341 has been predicted from crystal structure as an important residue for thyroid hormone receptor beta (TRβ) function, but this has never been confirmed in functional studies. Here, a novel p.L341V mutation as a cause...
Inflammatory biomarkers in Alzheimer's disease plasma.
Angharad R Morgan, Samuel Touchard, Claire Leckey, Caroline O'Hagan, Alejo J Nevado-Holgado, NIMA Consortium, Frederik Barkhof, Lars Bertram, Olivier Blin, Isabelle Bos, Valerija Dobricic, Sebastiaan Engelborghs, Giovanni Frisoni, Lutz Frölich, Silvey Gabel, Peter Johannsen, Petronella Kettunen, Iwona Kłoszewska, Cristina Legido-Quigley, Alberto Lleó, Pablo Martinez-Lage, Patrizia Mecocci, Karen Meersmans, José Luis Molinuevo, Gwendoline Peyratout, Julius Popp, Jill Richardson, Isabel Sala, Philip Scheltens, Johannes Streffer, Hikka Soininen, Mikel Tainta-Cuezva, Charlotte Teunissen, Magda Tsolaki, Rik Vandenberghe, Pieter Jelle Visser, Stephanie Vos, Lars-Olof Wahlund, Anders Wallin, Sarah Westwood, Henrik Zetterberg, Simon Lovestone, B Paul Morgan, Annex: NIMA–Wellcome Trust Consortium for Neuroimmunology of Mood Disorders and Alzheimer's Disease
Jul 23, 2019
INTRODUCTION: Plasma biomarkers for Alzheimer's disease (AD) diagnosis/stratification are a "Holy Grail" of AD research and intensively sought; however, there are no well-established plasma markers. METHODS: A hypothesis-led...
Ursinus College Bulletin, Spring 1984
Donald Lawrence Helfferich, 1898-1984 Past and presence of Zacharias Ursinus What were they fighting about? Heidelberg Catechism Today's clergy take Reformation seriously A Homecoming for winners November 6: A Founders Day...
Ursinus College Collegeville Pennsylvania alumni Deaths Marriages Donald L. Helfferich Zacharias Ursinus Derk Visser Heidelberg Catechism Michael Price field hockey John Van Ness Nelson Williams William T. Parsons Maurice Armstrong sycamore tree Peter F. Small Higher Education Social History United States History
Published by: Ursinus College
The Grizzly, November 4, 1983
Perry Romer, John Zerr, Rosemary J. Wuenschel, Tracey Clark, Richard P. Richter, Alison K. Brown, Kurt Richter, Diane Nicander, Timothy Cosgrave, Scott Scheffler, Neil Brown, Jeffrey Jacobson
Jan 01, 0001
Got a Career? Convocation Set Visser Conducts Forum Ursinus Awaits Celebration Letters to the Editor: Grenada Forums Finally Finish Sixteenth-Century Play to Finish Sports Medicine - It's Where It's At! College With a...
Ursinus College Collegeville Pennsylvania newspaper Business Economics Council founder's' day Derk Visser Zacharias Ursinus George Fago ProTheatre Joseph S. Torg Lyman C. Ogilby Creedence Clearwater Revival Tohoku Gakuin University Colonial Philadelphia Historical Society Football Soccer cross country cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Neural stem cell temporal patterning and brain tumour growth rely on oxidative phosphorylation.
D. melanogaster Warburg effect brain tumours developmental biology Neural Stem Cells Oxidative Phosphorylation Regenerative Medicine Stem Cells temporal patterning tumour heterogeneity Animals Brain Neoplasms Cell Differentiation Cell Proliferation Disease Models Animal Drosophila Glycolysis Neural Stem Cells Oxidative Phosphorylation
TaDa! Analysing cell type-specific chromatin in vivo with Targeted DamID.
The emergence of neuronal diversity during development of the nervous system relies on dynamic changes in the epigenetic landscape of neural stem cells and their progeny. Targeted DamID (TaDa) is proving invaluable in...
Peripersonal and extrapersonal visuospatial neglect in different frames of reference
Antonia F Ten Brink, J Matthijs Biesbroek, Quirien Oort, Johanna M a Visser-Meily, Tanja C W Nijboer
Jan 01, 2019
INTRODUCTION: Visuospatial neglect can occur in peripersonal and extrapersonal space. The dorsal visual pathway is hypothesized to be associated with peripersonal, and the ventral pathway with extrapersonal neglect. We aimed to...
Dynamic assessment of visual neglect
Introduction: Visual neglect is a frequent disorder following stroke and is often diagnosed by neuropsychological assessment. However, paper-and-pencil tasks have low predictive value as they lack sensitivity to capture neglect...
Hygrothermal performance of bio-based insulation materials
Bio-based insulation materials have the potential to make a significant contribution to the reduction in the global warming potential of the construction industry world-wide. They contribute in two ways. First they provide the...
A carrier-assisted ChIP-seq method for estrogen receptor-chromatin interactions from breast cancer core needle biopsy samples.
Wilbert Zwart, Rutger Koornstra, Jelle Wesseling, Emiel Rutgers, Sabine Linn, Jason S Carroll
May 02, 2019
BACKGROUND: The Estrogen Receptor alpha (ERα) is the key transcriptional regulator in luminal breast cancer and is therefore the main target for adjuvant treatment of this subtype. Luminal gene signatures are dictated by the...
Peripersonal and extrapersonal visuospatial neglect in different frames of reference
Antonia F Ten Brink, J Matthijs Biesbroek, Quirien Oort, Johanna M a Visser-Meily, Tanja C W Nijboer
Jan 01, 2019
INTRODUCTION: Visuospatial neglect can occur in peripersonal and extrapersonal space. The dorsal visual pathway is hypothesized to be associated with peripersonal, and the ventral pathway with extrapersonal neglect. We aimed to...
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