The output of state-of-the-art reverse-engineering methods for biological networks is often based on the fitting of a mathematical model to the data. Typically, different datasets do not give single consistent network...
Neurodegenerative diseases such as Alzheimer's and Parkinson's impact millions of people worldwide. Early diagnosis has proven to greatly increase the chances of slowing down the diseases' progression. Correct diagnosis often...
Background: Identification of underlying mechanisms behind drugs side effects is of extreme interest and
importance in drugs discovery today. Therefore machine learning methodology, linking such different
multi features aspects...
IoT technology has been widely valued and applied, and the resulting massive IoT data brings many challenges to the traditional centralized data management, such as performance, privacy, and security challenges. This paper...
Cellular network data traffic can be offload onto opportunistic networks. This paper proposes a Distance-based Opportunistic Publish/Subscribe (DOPS) content dissemination model, which is composed of three layers: application...
BACKGROUND: Inflammation is a core element of many different, systemic and chronic diseases that usually involve an important autoimmune component. The clinical phase of inflammatory diseases is often the culmination of a long...
In recent years, there have been numerous developments toward solving multimodal tasks, aiming to learn a stronger representation than through a single modality. Certain aspects of the data can be particularly useful in this...
Structured illumination microscopy (SIM) has become an important technique for
optical super-resolution imaging because it allows a doubling of image resolution at speeds
compatible with live-cell imaging. However, the...
A significant seasonal variation in tuberculosis (TB) is observed in north India during 2006-2011, particularly in states like Himachal Pradesh, Haryana and Rajasthan. To quantify the seasonal variation, we measure average...
Recent analyses of human genome sequences have given rise to impressive advances in identifying non-synonymous single nucleotide polymorphisms (nsSNPs). By contrast, the annotation of nsSNPs and their links to diseases are...
Accurate identification of bitter peptides is of great importance for better understanding their biochemical and biophysical properties. To date, machine learning-based methods have become effective approaches for providing a...
A prime goal in systems biology is the comprehensive use of existing high-throughput genomic datasets to gain a better understanding of chromatin organization and genome function. In this report, we use chromatin...
Structured illumination microscopy (SIM) has become an important technique for optical super-resolution imaging because it allows a doubling of image resolution at speeds compatible with live-cell imaging. However, the...
Accurate identification of bitter peptides is of great importance for better understanding their biochemical and biophysical properties. To date, machine learning-based methods have become effective approaches for providing a...
BACKGROUND: Human embryonic stem cells (hESCs) potentially offer new routes to study, on the basis of the Developmental Origins of Health and Disease (DOHaD) concept, how the maternal environment during pregnancy influences the...
Tumor-homing peptides (THPs) are small peptides that can recognize and bind cancer cells specifically. To gain a better understanding of THPs' functional mechanisms, the accurate identification and characterization of THPs is...