Search
Results: 460
Editorial.
Roberta Di Pietro
Nov 09, 2011
RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display...
Reduction of the geomagnetic field delays Arabidopsis thaliana flowering time through downregulation of flowering-related genes.
Chiara Agliassa, Ravishankar Narayana, Cinzia M Bertea, Christopher T Rodgers, Massimo E Maffei
Jun 21, 2018
Variations in magnetic field (MF) intensity are known to induce plant morphological and gene expression changes. In Arabidopsis thaliana Col-0, near-null magnetic field (NNMF, i.e., <100 nT MF) causes a delay in the transition...
Arabidopsis thaliana delay in flowering time geomagnetic field leaves and floral meristem gene expression near-null magnetic field Arabidopsis Arabidopsis Proteins Cluster Analysis Down-Regulation Flowers Gene Expression Regulation Plant magnetic fields Meristem Plant Leaves Real-Time Polymerase Chain Reaction Time Factors
Dale J Waterhouse, Wladyslaw Januszewicz, Sharib Ali, Rebecca C Fitzgerald, Massimiliano di Pietro, Sarah E Bohndiek
Apr 16, 2021
Early detection of esophageal neoplasia enables curative endoscopic therapy, but the current diagnostic standard of care has low sensitivity because early neoplasia is often inconspicuous with conventional white-light endoscopy....
Structural connectome and connectivity lateralization of the multimodal vestibular cortical network.
Iole Indovina, Gianfranco Bosco, Roberta Riccelli, Vincenzo Maffei, Francesco Lacquaniti, Luca Passamonti, Nicola Toschi
Aug 14, 2020
Unlike other sensory systems, the structural connectivity patterns of the human vestibular cortex remain a matter of debate. Based on their functional properties and hypothesized centrality within the vestibular network, the...
Barrett's esophagus and cancer risk
Barrett's esophagus (BE) is the only known precursor to esophageal adenocarcinoma (EAC), whose incidence has increased sharply in the last 4 decades. The annual conversion rate of BE to cancer is significant, but small. The...
Research advances in esophageal diseases
Over the last year, significant steps have been made toward understanding the pathogenesis of esophageal diseases and translating this knowledge to clinical practice. Gastroesophageal reflux disease (GERD) is the most common...
A sinister black finding in the stomach.
Wladyslaw Januszewicz, Pippa Corrie, Hongxiang Liu, James Chan, Rebecca C Fitzgerald, Massimiliano di Pietro
Oct 08, 2019
A 68-year-old woman undergoing a routine surveillance endoscopy—part of her follow-up for a Barrett's oesophagus—was found to have a solitary, black lesion, approximately 4 mm in diameter, in the gastric body (figure).
Acrylonitrile Aged Aniline Compounds Barrett Esophagus Benzimidazoles Drug Therapy Combination endoscopy Digestive System Female Humans Liver Liver Neoplasms Magnetic Resonance Imaging Melanoma Mutation Neoplasm Metastasis Paclitaxel Prognosis Stomach Tomography X-Ray Computed Tubulin Modulators Uveal Neoplasms
Graph Representation Forecasting of Patient's Medical Conditions
Objective: Modern medicine needs to shift from a wait and react, curative discipline to a preventative, interdisciplinary science aiming at providing personalized, systemic, and precise treatment plans to patients. To this...
Mitochondrial DNA and traumatic brain injury.
Harry Bulstrode, James AR Nicoll, Gavin Hudson, Patrick F Chinnery, Valentina Di Pietro, Antonio Belli
Apr 12, 2019
OBJECTIVE: Traumatic brain injury (TBI) is a multifactorial pathology with great interindividual variability in response to injury and outcome. Mitochondria contain their own DNA (mtDNA) with genomic variants that have different...
The human squamous oesophagus has widespread capacity for clonal expansion from cells at diverse stages of differentiation.
Mariagnese Barbera, Massimiliano di Pietro, Elaine Walker, Charlotte Brierley, Shona MacRae, Benjamin D Simons, Phil H Jones, John Stingl, Rebecca C Fitzgerald
Feb 13, 2020
OBJECTIVE: Knowledge of the cellular mechanisms involved in homeostasis of human squamous oesophagus in the steady state and following chronic injury is limited. We aimed to better understand these mechanisms by using a...
Pilot randomized crossover study comparing the efficacy of transnasal disposable endosheath with standard endoscopy to detect Barrett's esophagus.
Mohammed K Shariff, Sibu Varghese, Maria O'Donovan, Zarah Abdullahi, Xinxue Liu, Rebecca C Fitzgerald, Massimiliano di Pietro
Feb 18, 2016
Revised British Society of Gastroenterology recommendation on the diagnosis and management of Barrett's oesophagus with low-grade dysplasia.
The most recent guidelines for the management of Barrett's oesophagus published in 2014 recommended endoscopic surveillance for patient with histological evidence of low-grade dysplasia (LGD) on random biopsies.1 In the last...
Autofluorescence-Directed Confocal Endomicroscopy in Combination With a Three-Biomarker Panel Can Inform Management Decisions in Barrett's Esophagus.
Massimiliano di Pietro, Elizabeth L Bird-Lieberman, Xinxue Liu, Tara Nuckcheddy-Grant, Helga Bertani, Maria O'Donovan, Rebecca C Fitzgerald
Nov 16, 2015
Aged Algorithms Aneuploidy Barrett Esophagus Biomarkers Biopsy Cyclin A Disease Progression Esophagoscopy esophagus False Positive Reactions Female Humans Male Microscopy Confocal Middle Aged Narrow Band Imaging Optical Imaging Precancerous Conditions Sensitivity and Specificity Tumor Suppressor Protein p53 Watchful Waiting
Endoscopic measurement of gastric pH associates with persistent acid reflux in patients treated with proton-pump inhibitors for gastroesophageal reflux disease.
Wladyslaw Januszewicz, James Hartley, William Waldock, Geoffrey Roberts, Bincy Alias, Anthony Hobson, Lorenz Wernisch, Massimiliano di Pietro
Aug 13, 2020
BACKGROUND: Proton-pump inhibitors (PPIs) are the mainstay of gastroesophageal reflux disease (GERD) treatment, however, up to 30% of patients have a poor symptomatic response. PH-impedance is the gold standard to assess whether...
Design and validation of a near-infrared fluorescence endoscope for detection of early esophageal malignancy.
Dale J Waterhouse, James Joseph, André A Neves, Massimiliano di Pietro, Kevin M Brindle, Rebecca C Fitzgerald, Sarah E Bohndiek
Aug 23, 2016
A clinically translatable hyperspectral endoscopy (HySE) system for imaging the gastrointestinal tract.
Jonghee Yoon, James Joseph, Dale J Waterhouse, A Siri Luthman, George SD Gordon, Massimiliano di Pietro, Wladyslaw Januszewicz, Rebecca C Fitzgerald, Sarah E Bohndiek
Mar 14, 2019
Hyperspectral imaging (HSI) enables visualisation of morphological and biochemical information, which could improve disease diagnostic accuracy. Unfortunately, the wide range of image distortions that arise during flexible...
Parapred
MOTIVATION: Antibodies play essential roles in the immune system of vertebrates and are powerful tools in research and diagnostics. While hypervariable regions of antibodies, which are responsible for binding, can be readily...
The risk of neoplasia in patients with Barrett's esophagus indefinite for dysplasia
Richard Phillips, Wladyslaw Januszewicz, Nastazja D Pilonis, Maria O'Donovan, Tarek Sawas, David A Katzka, Rebecca C Fitzgerald, Massimiliano di Pietro
Feb 19, 2021
Managerial Discretion in Accruals and Informational Efficiency
In this paper, we examine the relation between managerial discretion in accruals and informational efficiency. We measure managerial discretion in accruals by the absolute value of abnormal accruals. Assuming that efficient...
Managerial Discretion in Accruals and Informational Efficiency
In this paper, we examine the relation between managerial discretion in accruals and informational efficiency. We measure managerial discretion in accruals by the absolute value of abnormal accruals. Assuming that efficient...
Output-Based Measurement of Accounting Comparability
Accounting comparability has been the subject of significant interest in empirical financial accounting research. Recent literature, particularly that following De Franco et al.’s (2011) influential study, has focused on...
|
|< |
< |
1 |