IDO1 + Paneth cells promote immune escape of colorectal cancer
Sandra Pflügler,
Jasmin Svinka,
Irene Scharf,
Ilija Crncec,
Martin Filipits,
Pornpimol Charoentong,
Markus Tschurtschenthaler,
Lukas Kenner,
Monira Awad,
Judith Stift,
Marina Schernthanner,
Romana Bischl,
Dietmar Herndler-Brandstetter,
Elisabeth Glitzner,
Herwig P. Moll,
Emilio Casanova,
Gerald Timelthaler,
Maria Sibilia,
Michael Gnant,
Sigurd Lax,
Josef Thaler,
Mathias Müller,
Birgit Strobl,
Thomas Mohr,
Arthur Kaser,
Zlatko Trajanoski,
Gerwin Heller,
Robert Eferl
May 22, 2021
Abstract: Tumors have evolved mechanisms to escape anti-tumor immunosurveillance. They limit humoral and cellular immune activities in the stroma and render tumors resistant to immunotherapy. Sensitizing tumor cells to immune...