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An Invariant Arginine in Common with MHC Class II Allows Extension at the C-Terminal End of Peptides Bound to Chicken MHC Class I.
Jin Xiao, Wangzhen Xiang, Yongli Zhang, Weiyu Peng, Min Zhao, Ling Niu, Yan Chai, Jianxun Qi, Fei Wang, Peng Qi, Chungang Pan, Lingxia Han, Ming Wang, Jim Kaufman, George F Gao, William J Liu
Dec 17, 2018
MHC molecules are found in all jawed vertebrates and are known to present peptides to T lymphocytes. In mammals, peptides can hang out either end of the peptide-binding groove of classical class II molecules, whereas the N and C...
End-to-End Deep Learning of Non-rigid Groupwise Registration and Reconstruction of Dynamic MRI.
Temporal correlation has been exploited for accelerated dynamic MRI reconstruction. Some methods have modeled inter-frame motion into the reconstruction process to produce temporally aligned image series and higher...
Why is reporting quality improvement so hard? A qualitative study in perioperative care.
OBJECTIVES: Quality improvement (QI) may help to avert or mitigate the risks of suboptimal care, but it is often poorly reported in the healthcare literature. We aimed to identify the influences on reporting QI in the area of...
Collectin-11 detects stress-induced L-fucose pattern to trigger renal epithelial injury.
Conrad A Farrar, David Tran, Ke Li, Weiju Wu, Qi Peng, Wilhelm Schwaeble, Wuding Zhou, Steven H Sacks
Apr 12, 2019
Physiochemical stress induces tissue injury as a result of the detection of abnormal molecular patterns by sensory molecules of the innate immune system. Here, we have described how the recently discovered C-type lectin...
Local blood pressure associates with the degree of luminal stenosis in patients with atherosclerotic disease in the middle cerebral artery.
Yuanliang Jiang, Wenjia Peng, Zhongzhao Teng, Jonathan H Gillard, Bo Hong, Qi Liu, Jianping Lu
Oct 11, 2016
A Leucine Aminopeptidase-Activated Theranostic Prodrug for Cancer Diagnosis and Chemotherapy
Feiyi Wang, Sisi Hu, Qi Sun, Qiang Fei, Chao Ma, Cuifen Lu, Junqi Nie, Zuxing Chen, Jun Ren, Guo Rong Chen, Guichun Yang, Xiao Peng He, Tony D. James
Nov 18, 2019
Currently, chemotherapy is a widely used and important treatment for cancer. However, almost all of the treatments have shortcomings associated with poor specificity and high toxicity, which results in severe side effects to...
bioimaging Chemotherapy leucine aminopeptidase sensor theranostic prodrugs /dk/atira/pure/subjectarea/asjc/2500/2502 name=Biomaterials /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry /dk/atira/pure/subjectarea/asjc/2200/2204 name=Biomedical Engineering /dk/atira/pure/subjectarea/asjc/2700/2704 name=Biochemistry, medical /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Determining the skills needed by frontline NHS staff to deliver quality improvement
BACKGROUND: Previous studies have detailed the technical, learning and soft skills healthcare staff deploy to deliver quality improvement (QI). However, research has mainly focused on management and leadership skills...
A Board Level Intervention to Develop Organisation-Wide Quality Improvement Strategies
Estela Capelas Barbosa, Lorelei Jones, Linda Pomeroy, Glenn Robert, Susan Burnett, Janet E Anderson, Steve Morris, Fulop Naomi
Aug 26, 2020
BACKGROUND: Hospital boards have statutory responsibility for upholding the quality of care in their organisations. International research on quality in hospitals resulted in a research-based guide to help senior hospital...
A Leucine Aminopeptidase-Activated Theranostic Prodrug for Cancer Diagnosis and Chemotherapy
Feiyi Wang, Sisi Hu, Qi Sun, Qiang Fei, Chao Ma, Cuifen Lu, Junqi Nie, Zuxing Chen, Jun Ren, Guo Rong Chen, Guichun Yang, Xiao Peng He, Tony D. James
Nov 18, 2019
Currently, chemotherapy is a widely used and important treatment for cancer. However, almost all of the treatments have shortcomings associated with poor specificity and high toxicity, which results in severe side effects to...
bioimaging Chemotherapy leucine aminopeptidase sensor theranostic prodrugs /dk/atira/pure/subjectarea/asjc/2500/2502 name=Biomaterials /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry /dk/atira/pure/subjectarea/asjc/2200/2204 name=Biomedical Engineering /dk/atira/pure/subjectarea/asjc/2700/2704 name=Biochemistry, medical /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Target Enzyme-Activated Two-Photon Fluorescent Probes
Jing Ning, Wei Wang, Guangbo Ge, Peng Chu, Feida Long, Yongliang Yang, Yulin Peng, Lei Feng, Xiaochi Ma, Tony D. James
Jul 15, 2019
The rapid development of fluorescent probes for monitoring target enzymes is still a great challenge owing to the lack of efficient ways to optimize a specific fluorophore. Herein, a practical two-dimensional strategy was...
One-Stop Smart Urban Apps and Determinants of Their Continuance Usage
This study aimed to explore factors affecting continual usage of one-stop smart urban apps, which is the key to realise the vision of smart cities. A questionnaire (involved a total of 578 users/citizens) was carried out to test...
Published by: IGI Global Scientific Publishing
Target Enzyme-Activated Two-Photon Fluorescent Probes
Jing Ning, Wei Wang, Guangbo Ge, Peng Chu, Feida Long, Yongliang Yang, Yulin Peng, Lei Feng, Xiaochi Ma, Tony D. James
Jul 15, 2019
The rapid development of fluorescent probes for monitoring target enzymes is still a great challenge owing to the lack of efficient ways to optimize a specific fluorophore. Herein, a practical two-dimensional strategy was...
A modified Delphi study to identify the features of high quality measurement plans for healthcare improvement projects.
Thomas Woodcock, Yewande Adeleke, Christine Goeschel, Peter Pronovost, Mary Dixon-Woods
Feb 15, 2020
BACKGROUND:The design and execution of measurement in quality improvement (QI) initiatives is often poor. Better guidance on "what good looks like" might help to mitigate some of the problems. We report a consensus-building...
Published by: BMC medical research methodology
Metabolically Specific In Situ Fluorescent Visualization of Bacterial Infection on Wound Tissues
Chen Jian Zhong, Xi Le Hu, Xiao Lan Yang, Hui Qi Gan, Kai Cheng Yan, Fu Ting Shu, Pei Wei, Teng Gong, Peng Fei Luo, Tony D. James, Zhao Hong Chen, Yong Jun Zheng, Xiao Peng He, Zhao Fan Xia
Sep 07, 2022
The ability to effectively detect bacterial infection in human tissues is important for the timely treatment of the infection. However, traditional techniques fail to visualize bacterial species adhered to host cells in situ...
An assessment on the incremental value of high-resolution magnetic resonance imaging to identify culprit plaques in atherosclerotic disease of the middle cerebral artery.
Zhongzhao Teng, Wenjia Peng, Qian Zhan, Xuefeng Zhang, Qi Liu, Shiyue Chen, Xia Tian, Luguang Chen, Adam J Brown, Martin J Graves, Jonathan H Gillard, Jianping Lu
Sep 04, 2015
Magnetic Resonance Imaging Middle Cerebral Artery Minimum luminal area Plaque burden Stenosis Aged Case-Control Studies Cerebral Angiography Cerebrovascular Disorders Constriction Pathologic Diffusion Magnetic Resonance Imaging Female Humans Image Processing Computer-Assisted Intracranial Arteriosclerosis Magnetic Resonance Angiography Magnetic Resonance Imaging Male Middle Aged Middle Cerebral Artery Plaque Atherosclerotic Predictive Value of Tests Sensitivity and Specificity
Metabolically Specific In Situ Fluorescent Visualization of Bacterial Infection on Wound Tissues
Chen Jian Zhong, Xi Le Hu, Xiao Lan Yang, Hui Qi Gan, Kai Cheng Yan, Fu Ting Shu, Pei Wei, Teng Gong, Peng Fei Luo, Tony D. James, Zhao Hong Chen, Yong Jun Zheng, Xiao Peng He, Zhao Fan Xia
Sep 07, 2022
The ability to effectively detect bacterial infection in human tissues is important for the timely treatment of the infection. However, traditional techniques fail to visualize bacterial species adhered to host cells in situ...
Mapping outcomes in quality improvement and system design activities
BACKGROUND: Whether explicit or implicit, models of value are fundamental in quality improvement (QI) initiatives. They embody the desirability of the impact of interventions-with either foresight or hindsight. Increasingly...
A modified Delphi study to identify the features of high quality measurement plans for healthcare improvement projects.
Thomas Woodcock, Yewande Adeleke, Christine Goeschel, Peter Pronovost, Mary Dixon-Woods
Jan 20, 2020
BACKGROUND: The design and execution of measurement in quality improvement (QI) initiatives is often poor. Better guidance on "what good looks like" might help to mitigate some of the problems. We report a consensus-building...
Characterizing Human Collective Behaviors During COVID-19 - Hong Kong SAR, China, 2020.
Zhanwei Du, Xiao Zhang, Lin Wang, Sidan Yao, Yuan Bai, Qi Tan, Xiaoke Xu, Sen Pei, Jingyi Xiao, Tim K Tsang, Qiuyan Liao, Eric HY Lau, Peng Wu, Chao Gao, Benjamin J Cowling
Mar 16, 2023
WHAT IS ALREADY KNOWN ABOUT THIS TOPIC?: People are likely to engage in collective behaviors online during extreme events, such as the coronavirus disease 2019 (COVID-19) crisis, to express awareness, take action, and work...
Dynamic Research on Youth Thought, Behavior, and Growth Law Based on Deep Learning Algorithm
Qi Fu
Apr 01, 2023
The growth and development of youth is related to the destiny of the country and the nation, and the cultivation of young people in the new era is of great significance. Youth is a special stage in life, and the ideological and...
Published by: IGI Global Scientific Publishing
A think-aloud method of investigating translanguaging strategies in learning Chinese characters
Asian scripts that are significantly different from Roman-derived alphabets usually impose difficulties in learning. Translanguaging has therefore been explored as a pedagogical tool for the language classroom, including...
Progress towards understanding protein S-acylation
S-acylation, also known as S-palmitoylation or palmitoylation, is a reversible post-translational lipid modification in which long chain fatty acid, usually the 16-carbon palmitate, covalently attaches to a cysteine residue(s)...
How Does User Social Network Improve Innovation Outcomes on a Virtual Innovation Platform?
Previous studies demonstrate that online interactive relations can help improve users' innovation outcomes, yet few studies have investigated how they influence user innovation. This paper builds a social network based on users'...
Published by: IGI Global Scientific Publishing
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