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Stanford Moore and William H. Stein, 1957
The Rockefeller University
Jan 01, 0001
Stanford Moore and William H. Stein. Determinations of the structure of proteins: studies on ribonuclease.
Lecture delivered February 21, 1957
Posted with permission
Published by: Academic Press Inc., Publishers
Cryo-EM structure of the Rhodospirillum rubrum RC-LH1 complex at 2.5 Å.
Pu Qian, Tristan I Croll, David JK Swainsbury, Pablo Castro-Hartmann, Nigel W Moriarty, Kasim Sader, C Neil Hunter
Nov 10, 2021
The reaction centre light-harvesting 1 (RC-LH1) complex is the core functional component of bacterial photosynthesis. We determined the cryo-electron microscopy (cryo-EM) structure of the RC-LH1 complex from Rhodospirillum...
Carotenoids cryo-electron microscopy light-harvesting Photosynthesis Quinone reaction centre Bacterial Proteins Bacteriochlorophylls Benzoquinones Binding Sites Cryoelectron Microscopy Crystallization Electron Transport Complex III Hydrogen Bonding Hydroquinones Ligands Light-Harvesting Protein Complexes Phospholipids Protein Conformation alpha-Helical Rhodospirillum rubrum
Quantifying moment redistribution in FRP-strengthened RC beams
Consideration of moment redistribution (MR) in the design of continuous reinforced concrete (RC) beams results in an efficient and economical design. Adding fibre-reinforced polymer (FRP) materials to RC structures to enhance...
Quantifying moment redistribution in FRP-strengthened RC beams
Consideration of moment redistribution (MR) in the design of continuous reinforced concrete (RC) beams results in an efficient and economical design. Adding fibre-reinforced polymer (FRP) materials to RC structures to enhance...
In-depth immunophenotyping data of IL-6R on the human peripheral regulatory T cell (Treg) compartment
RC Ferreira, DB Rainbow, A Rubio García, ML Pekalski, L Porter, JJ Oliveira, F Waldron-Lynch, LS Wicker, JA Todd
Jul 04, 2017
We provide in this paper a detailed characterization of the human peripheral CD4$^+$ CD127$^{low}$CD25$^+$ regulatory T cell (Treg) compartment, with a particular emphasis in defining the population expressing higher levels of...
Prediction of capacity for moment redistribution in FRP-strengthened continuous RC T-beams
Due to the premature debonding of fiber-reinforced polymer (FRP) materials which results in a reduction in 14 ductility, the problem of how to exploit moment redistribution (MR) in FRP-strengthened continuous 15 reinforced...
Prediction of capacity for moment redistribution in FRP-strengthened continuous RC T-beams
Due to the premature debonding of fiber-reinforced polymer (FRP) materials which results in a reduction in 14 ductility, the problem of how to exploit moment redistribution (MR) in FRP-strengthened continuous 15 reinforced...
Influence of Photoplethysmogram Signal Quality on Pulse Arrival Time during Polysomnography.
Intervals of low-quality photoplethysmogram (PPG) signals might lead to significant inaccuracies in estimation of pulse arrival time (PAT) during polysomnography (PSG) studies. While PSG is considered to be a "gold standard"...
The NRG1 gene is frequently silenced by methylation in breast cancers and is a strong candidate for the 8p tumour suppressor gene.
YL Chua, Y Ito, JCM Pole, S Newman, S-F Chin, RC Stein, IO Ellis, C Caldas, MJ O'Hare, A Murrell, PAW Edwards
Dec 03, 2020
Neuregulin-1 (NRG1) is both a candidate oncogene and a candidate tumour suppressor gene. It not only encodes the heregulins and other mitogenic ligands for the ERBB family, but also causes apoptosis in NRG1-expressing cells. We...
Cell Line Tumor Chromosomes Human Pair 8 Humans Breast Neoplasms Chromosome Aberrations Genetic Predisposition to Disease Neuregulin-1 Chromosome Mapping Cell Proliferation DNA Methylation Gene Expression Regulation Neoplastic Gene Silencing Base Sequence CpG Islands Genes Tumor Suppressor Transcription Initiation Site Female
Attachment representations and socio-emotional difficulties in alternative care
Attachment has been assessed in children living in alternative care (AC) settings, such as Residential Homes (RC) and Foster Care (FC). However, no study has been conducted to compare attachment styles in residential, foster and...
Linear mixed models for replication data to efficiently allow for covariate measurement error
It is well known that measurement error in the covariates of regression models generally causes bias in parameter estimates. Correction for such biases requires information concerning the measurement error, which is often in...
An evaluation of the Johanson model for roller compaction process development for a high dose API
Kevin M. Moroney, Patrick Cronin, Opeyemi A. Adeleye, Barbara E. Schaller, Matthew A. Howard, Bernardo Castro-Dominguez, Rohit Ramachandran, Gavin M. Walker
Apr 15, 2020
Roller compaction (RC) is a dry granulation technique applied to improve the flow and compressibility of drug formulations. RC implementation for high drug load formulations can be challenging due to flow issues and a high...
2.4-Å structure of the double-ring Gemmatimonas phototrophica photosystem.
Pu Qian, Alastair T Gardiner, Ivana Šímová, Katerina Naydenova, Tristan I Croll, Philip J Jackson, Nupur, Miroslav Kloz, Petra Čubáková, Marek Kuzma, Yonghui Zeng, Pablo Castro-Hartmann, Bart van Knippenberg, Kenneth N Goldie, David Kaftan, Pavel Hrouzek, Jan Hájek, Jon Agirre, C Alistair Siebert, David Bína, Kasim Sader, Henning Stahlberg, Roman Sobotka, Christopher J Russo, Tomáš Polívka, C Neil Hunter, Michal Koblížek
Mar 19, 2022
Phototrophic Gemmatimonadetes evolved the ability to use solar energy following horizontal transfer of photosynthesis-related genes from an ancient phototrophic proteobacterium. The electron cryo-microscopy structure of the...
An evaluation of the Johanson model for roller compaction process development for a high dose API
Kevin M. Moroney, Patrick Cronin, Opeyemi A. Adeleye, Barbara E. Schaller, Matthew A. Howard, Bernardo Castro-Dominguez, Rohit Ramachandran, Gavin M. Walker
Apr 15, 2020
Roller compaction (RC) is a dry granulation technique applied to improve the flow and compressibility of drug formulations. RC implementation for high drug load formulations can be challenging due to flow issues and a high...
Respiratory chain deficiency in nonmitochondrial disease.
Angela Pyle, Helen J Nightingale, Helen Griffin, Angela Abicht, Janbernd Kirschner, Ivo Baric, Mario Cuk, Konstantinos Douroudis, Lea Feder, Markus Kratz, Birgit Czermin, Stephanie Kleinle, Mauro Santibanez-Koref, Veronika Karcagi, Elke Holinski-Feder, Patrick F Chinnery, Rita Horvath
Mar 07, 2019
OBJECTIVE: In this study, we report 5 patients with heterogeneous phenotypes and biochemical evidence of respiratory chain (RC) deficiency; however, the molecular diagnosis is not mitochondrial disease. METHODS: The reported...
Linear mixed models for replication data to efficiently allow for covariate measurement error
It is well known that measurement error in the covariates of regression models generally causes bias in parameter estimates. Correction for such biases requires information concerning the measurement error, which is often in...
Attachment representations and socio-emotional difficulties in alternative care
Attachment has been assessed in children living in alternative care (AC) settings, such as Residential Homes (RC) and Foster Care (FC). However, no study has been conducted to compare attachment styles in residential, foster and...
How good are GPs at adhering to a pragmatic trial protocol in primary care? Results from the ADDITION-Cambridge cluster-randomized pragmatic trial
Objective: To assess the fidelity of general practitioners’ (GP) adherence to a long term pragmatic trial protocol.
Design: Retrospective analyses of electronic primary care records of participants in the pragmatic...
The resistance-compliance product of the pulmonary circulation varies in health and pulmonary vascular disease.
Pulmonary vascular resistance (PVR) is traditionally used to describe pulmonary hemodynamic characteristics. However, it does not take into account pulmonary artery compliance (Ca) or pulsatile flow. The product of PVR and Ca is...
HELIX-RC
Simone Campanoni, Kevin Brownell, Svilen Kanev, Timothy M Jones, Gu-Yeon Wei, David Brooks
Mar 10, 2015
p53 shapes genome-wide and cell type-specific changes in microRNA expression during the human DNA damage response.
Hiroyoshi Hattori, Rekin's Janky, Wilfried Nietfeld, Stein Aerts, M Madan Babu, Ashok R Venkitaraman
Feb 13, 2020
The human DNA damage response (DDR) triggers profound changes in gene expression, whose nature and regulation remain uncertain. Although certain micro-(mi)RNA species including miR34, miR-18, miR-16 and miR-143 have been...
AP-1 activator protein-1 DDR DNA damage response DNA damage response E2F1 transcription factor E2F1 FOXM1 forkhead box protein M1 NF-k B nuclear factor-k B NGS next-generation sequencing TF transcription factor TP53 tumour protein p53 clinical outcome computational analysis double stranded DNA breaks DSBs ionizing radiation IR miRNA micro-RNA micro-RNA misc RNA miscellaneous RNA next-generation sequencing p53 scRNA small cytoplasmic RNA snRNA small nuclear RNA snoRNA small nucleolar RNA tRNA transfer RNA Cell Line DNA Damage DNA Repair Gene Expression Regulation Gene Expression Regulation Neoplastic Genome Genome Human Humans MicroRNAs Neoplasms Organ Specificity Tumor Suppressor Protein p53
Neuronal cell types in the fly
At around 150 000 neurons, the adult Drosophila melanogaster central nervous system is one of the largest species, for which a complete cellular catalogue is imminent. While numerically much simpler than mammalian brains, its...
Review: The Anthropology of Economy
F Stein
Mar 13, 2017
With Anthropology and Economy, Stephen Gudeman has provided us with a valuable resource for teaching and rethinking the study of economic life. His book fulfils two important purposes.
On the one hand, as an introductory text it...
A Study of Pile Fatigue Failures in the Arabian Gulf
Leanne Mary Stein
Apr 09, 2013
In the summer of 1974, construction commenced for an oil tanker terminal in the Arabian Gulf. The following winter, a particularly strong tropical storm hit after the piles were driven, prior to installation of the...
Published by: Memorial University of Newfoundland
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