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Personalized Mobile Learning and Course Recommendation System
Mobile-based learning provides new experience to the learners to learn anything from anywhere and anytime by using their portable or mobile device. Vast educational contents and also different media formats can be supported by...
Published by: IGI Global Scientific Publishing
The repertoire of mutational signatures in human cancer.
Ludmil B Alexandrov, Jaegil Kim, Nicholas J Haradhvala, Mi Ni Huang, Alvin Wei Tian Ng, Yang Wu, Arnoud Boot, Kyle R Covington, Dmitry A Gordenin, Erik N Bergstrom, SM Ashiqul Islam, Nuria Lopez-Bigas, Leszek J Klimczak, John R McPherson, Sandro Morganella, Radhakrishnan Sabarinathan, David A Wheeler, Ville Mustonen, PCAWG Mutational Signatures Working Group, Gad Getz, Steven G Rozen, Michael R Stratton, PCAWG Consortium
Feb 04, 2021
Somatic mutations in cancer genomes are caused by multiple mutational processes, each of which generates a characteristic mutational signature1. Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium2 of...
A memory clinic v. traditional community mental health team service
Judy Sasha Rubinsztein, Marelna Janse van Rensburg, Zerak Al-Salihy, Deborah Girling, Louise Lafortune, Muralikrishnan Radhakrishnan, Carol Brayne
Aug 05, 2020
Aims and method To compare the cost and quality of a memory-clinic-based service (MCS) with a traditional community mental health team (CMHT) service. Using a retrospective case-note review, we studied two groups, each with 33...
MANUFACTURING MULTI-MATRIX COMPOSITES:
The formation of porosity is a major challenge in any composite manufacturing process, particularly in the absence of vacuum assistance. Highly localised injection of polymer matrix into regions of interest in a dry preform is a...
MANUFACTURING MULTI-MATRIX COMPOSITES:
The formation of porosity is a major challenge in any composite manufacturing process, particularly in the absence of vacuum assistance. Highly localised injection of polymer matrix into regions of interest in a dry preform is a...
Black bone MRI with 3D reconstruction for the detection of skull fractures in children with suspected abusive head trauma.
Stephen F Kralik, Nucharin Supakul, Isaac C Wu, Gaspar Delso, Rupa Radhakrishnan, Chang Y Ho, Karen A Eley
Dec 11, 2019
PURPOSE: The purpose of this study was to determine the accuracy of "black bone" (BB) MRI for the detection of skull fractures in children with potential abusive head trauma. METHODS: A total of 34 pediatric patients were...
Feature Extraction From Single-Channel EEG Using Tsfresh and Stacked Ensemble Approach for Sleep Stage Classification
The smart world under Industry 4.0 is witnessing a notable spurt in sleep disorders and sleep-related issues in patients. Artificial intelligence and IoT are taking a giant leap in connecting sleep patients remotely with...
Published by: IGI Global Scientific Publishing
Comparative effectiveness of cognitive therapies delivered face-to-face or over the telephone
Geoffrey C Hammond, Tim J Croudace, Muralikrishnan Radhakrishnan, Louise Lafortune, Alison Watson, Fiona McMillan-Shields, Peter B Jones
Aug 05, 2020
OBJECTIVES: To compare the clinical and cost-effectiveness of face-to-face (FTF) with over-the-telephone (OTT) delivery of low intensity cognitive behavioural therapy. DESIGN: Observational study following SROBE guidelines....
A Novel Trust Model for Secure Group Communication in Distributed Computing
Distributed networks are networks in which each node can act as a server or client and hence any node can provide service to any other node. In such a scenario, establishing a trust model between the service providing user and...
Published by: IGI Global Scientific Publishing
A combination of chitooligosaccharide and lipochitooligosaccharide recognition promotes arbuscular mycorrhizal associations in Medicago truncatula.
Feng Feng, Jongho Sun, Guru V Radhakrishnan, Tak Lee, Zoltán Bozsóki, Sébastien Fort, Aleksander Gavrin, Kira Gysel, Mikkel B Thygesen, Kasper Røjkjær Andersen, Simona Radutoiu, Jens Stougaard, Giles ED Oldroyd
Nov 09, 2020
Plants associate with beneficial arbuscular mycorrhizal fungi facilitating nutrient acquisition. Arbuscular mycorrhizal fungi produce chitooligosaccharides (COs) and lipo-chitooligosaccharides (LCOs), that promote symbiosis...
The Science of the Self (ātmavidyā)
A Barua
Jul 10, 2017
A distinctive claim of some of the configurations of ‘modern Hinduism’ is that ancient Vedic wisdom foreshadows some contemporary scientific and technological advances, or provides a spiritual framework within which the current...
Cost-effectiveness of early intervention services for psychosis and fidelity to national policy implementation guidance.
Needle(s) in the Haystack – Synchronous Multifocal Tumor Induced Osteomalacia
Anand K. Annamalai, Krishnaswamy Sampathkumar, Shubhada Kane, Nitin S. Shetty, Suyash Kulkarni, Venkatesh Rangarajan, Nilendu Purandare, Prathamesh S. Pai, Ankit D. Mahuvakar, Radhakrishnan Shanthi, Govindarajulu Suriyakumar, Vipla Puri, Aram Subramaniam, Chandrasekhar Gopalakrishnan, Mathirajan Chelian, K. G. Srinivasan, Anthony J. Gill, Mark Gurnell, Roderick Clifton-Bligh
Feb 23, 2016
A combination of chitooligosaccharide and lipochitooligosaccharide recognition promotes arbuscular mycorrhizal associations in Medicago truncatula.
Feng Feng, Jongho Sun, Guru V Radhakrishnan, Tak Lee, Zoltán Bozsóki, Sébastien Fort, Aleksander Gavrin, Kira Gysel, Mikkel B Thygesen, Kasper Røjkjær Andersen, Simona Radutoiu, Jens Stougaard, Giles E D Oldroyd
Dec 10, 2019
Plants associate with beneficial arbuscular mycorrhizal fungi facilitating nutrient acquisition. Arbuscular mycorrhizal fungi produce chitooligosaccharides (COs) and lipo-chitooligosaccharides (LCOs), that promote symbiosis...
Needle(s) in the Haystack-Synchronous Multifocal Tumor-Induced Osteomalacia.
Anand K Annamalai, Krishnaswamy Sampathkumar, Shubhada Kane, Nitin S Shetty, Suyash Kulkarni, Venkatesh Rangarajan, Nilendu Purandare, Prathamesh S Pai, Ankit D Mahuvakar, Radhakrishnan Shanthi, Govindarajulu Suriyakumar, Vipla Puri, Subramaniam Aram, Chandrasekhar Gopalakrishnan, Mathirajan Chelian, KG Srinivasan, Anthony J Gill, Mark Gurnell, Roderick Clifton-Bligh
Jan 14, 2016
SNP in human ARHGEF3 promoter is associated with DNase hypersensitivity, transcript level and platelet function, and Arhgef3 KO mice have increased mean platelet volume
S Zou, AM Teixeira, M Kostadima, WJ Astle, A Radhakrishnan, LM Simon, L Truman, JS Fang, J Hwa, P-X Zhang, P van der Harst, PF Bray, WH Ouwehand, M Frontini, DS Krause
Aug 07, 2017
Executive summary of the KDIGO 2021 Guideline for the Management of Glomerular Diseases.
Brad H Rovin, Sharon G Adler, Jonathan Barratt, Frank Bridoux, Kelly A Burdge, Tak Mao Chan, H Terence Cook, Fernando C Fervenza, Keisha L Gibson, Richard J Glassock, David RW Jayne, Vivekanand Jha, Adrian Liew, Zhi-Hong Liu, Juan M Mejía-Vilet, Carla M Nester, Jai Radhakrishnan, Elizabeth M Rave, Heather N Reich, Pierre Ronco, Jan-Stephan F Sanders, Sanjeev Sethi, Yusuke Suzuki, Sydney CW Tang, Vladimír Tesar, Marina Vivarelli, Jack FM Wetzels, Lyubov Lytvyn, Jonathan C Craig, David J Tunnicliffe, Martin Howell, Marcello A Tonelli, Michael Cheung, Amy Earley, Jürgen Floege
Nov 10, 2021
The Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline for the Management of Glomerular Diseases is an update to the KDIGO 2012 guideline. The aim is to assist clinicians caring for individuals with...
AAV ANCA C3 FSGS IgA nephropathy IgA Vasculitis KDIGO MPGN anti-GBM complement evidence-based glomerular diseases glomerulonephritis Guideline infection-related glomerulonephritis Lupus Nephritis membranous nephropathy minimal change disease Nephrotic syndrome Systematic review Adult Child glomerulonephritis glomerulonephritis IGA glomerulonephritis Membranous Humans Kidney Nephrosis Lipoid
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes.
Esther Rheinbay, Morten Muhlig Nielsen, Federico Abascal, Jeremiah A Wala, Ofer Shapira, Grace Tiao, Henrik Hornshøj, Julian M Hess, Randi Istrup Juul, Ziao Lin, Lars Feuerbach, Radhakrishnan Sabarinathan, Tobias Madsen, Jaegil Kim, Loris Mularoni, Shimin Shuai, Andrés Lanzós, Carl Herrmann, Yosef E Maruvka, Ciyue Shen, Samirkumar B Amin, Pratiti Bandopadhayay, Johanna Bertl, Keith A Boroevich, John Busanovich, Joana Carlevaro-Fita, Dimple Chakravarty, Calvin Wing Yiu Chan, David Craft, Priyanka Dhingra, Klev Diamanti, Nuno A Fonseca, Abel Gonzalez-Perez, Qianyun Guo, Mark P Hamilton, Nicholas J Haradhvala, Chen Hong, Keren Isaev, Todd A Johnson, Malene Juul, Andre Kahles, Abdullah Kahraman, Youngwook Kim, Jan Komorowski, Kiran Kumar, Sushant Kumar, Donghoon Lee, Kjong-Van Lehmann, Yilong Li, Eric Minwei Liu, Lucas Lochovsky, Keunchil Park, Oriol Pich, Nicola D Roberts, Gordon Saksena, Steven E Schumacher, Nikos Sidiropoulos, Lina Sieverling, Nasa Sinnott-Armstrong, Chip Stewart, David Tamborero, Jose M C Tubio, Husen M Umer, Liis Uusküla-Reimand, Claes Wadelius, Lina Wadi, Xiaotong Yao, Cheng-Zhong Zhang, Jing Zhang, James E Haber, Asger Hobolth, Marcin Imielinski, Manolis Kellis, Michael S Lawrence, Christian von Mering, Hidewaki Nakagawa, Benjamin J Raphael, Mark A Rubin, Chris Sander, Lincoln D Stein, Joshua M Stuart, Tatsuhiko Tsunoda, David A Wheeler, Rory Johnson, Jüri Reimand, Mark Gerstein, Ekta Khurana, Peter J Campbell, Núria López-Bigas, Joachim Weischenfeldt, Rameen Beroukhim, Iñigo Martincorena, Jakob Skou Pedersen, Gad Getz
Mar 10, 2020
The discovery of drivers of cancer has traditionally focused on protein-coding genes1-4. Here we present analyses of driver point mutations and structural variants in non-coding regions across 2,658 genomes from the Pan-Cancer...
Published by: Nature
Standards for plant synthetic biology
Nicola J Patron, Diego Orzaez, Sylvestre Marillonnet, Heribert Warzecha, Colette Matthewman, Mark Youles, Oleg Raitskin, Aymeric Leveau, Gemma Farré, Christian Rogers, Alison Smith, Julian Hibberd, Alex AR Webb, James Locke, Sebastian Schornack, Jim Ajioka, David C Baulcombe, Cyril Zipfel, Sophien Kamoun, Jonathan DG Jones, Hannah Kuhn, Silke Robatzek, H Peter van Esse, Dale Sanders, Giles Oldroyd, Cathie Martin, Rob Field, Sarah O'Connor, Samantha Fox, Brande Wulff, Ben Miller, Andy Breakspear, Guru Radhakrishnan, Pierre-Marc Delaux, Dominique Loqué, Antonio Granell, Alain Tissier, Patrick Shih, Thomas P Brutnell, W Paul Quick, Heiko Rischer, Paul D Fraser, Asaph Aharoni, Christine Raines, Paul F South, Jean-Michel Ané, Björn R Hamberger, Jane Langdale, Jens Stougaard, Harro Bouwmeester, Michael Udvardi, James AH Murray, Vardis Ntoukakis, Patrick Schäfer, Katherine Denby, Keith J Edwards, Anne Osbourn, Jim Haseloff
Jun 13, 2019
DNA assembly GoldenGate Type IIS restriction endonucleases Cloning genetic syntax synthetic biology Botany Cloning Molecular DNA Deoxyribonucleases Type II Site-Specific Eukaryota Genetic Engineering Plants Plants Genetically Modified Plasmids Reference Standards synthetic biology Transcription Genetic
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes.
Esther Rheinbay, Morten Muhlig Nielsen, Federico Abascal, Jeremiah A Wala, Ofer Shapira, Grace Tiao, Henrik Hornshøj, Julian M Hess, Randi Istrup Juul, Ziao Lin, Lars Feuerbach, Radhakrishnan Sabarinathan, Tobias Madsen, Jaegil Kim, Loris Mularoni, Shimin Shuai, Andrés Lanzós, Carl Herrmann, Yosef E Maruvka, Ciyue Shen, Samirkumar B Amin, Pratiti Bandopadhayay, Johanna Bertl, Keith A Boroevich, John Busanovich, Joana Carlevaro-Fita, Dimple Chakravarty, Calvin Wing Yiu Chan, David Craft, Priyanka Dhingra, Klev Diamanti, Nuno A Fonseca, Abel Gonzalez-Perez, Qianyun Guo, Mark P Hamilton, Nicholas J Haradhvala, Chen Hong, Keren Isaev, Todd A Johnson, Malene Juul, Andre Kahles, Abdullah Kahraman, Youngwook Kim, Jan Komorowski, Kiran Kumar, Sushant Kumar, Donghoon Lee, Kjong-Van Lehmann, Yilong Li, Eric Minwei Liu, Lucas Lochovsky, Keunchil Park, Oriol Pich, Nicola D Roberts, Gordon Saksena, Steven E Schumacher, Nikos Sidiropoulos, Lina Sieverling, Nasa Sinnott-Armstrong, Chip Stewart, David Tamborero, Jose MC Tubio, Husen M Umer, Liis Uusküla-Reimand, Claes Wadelius, Lina Wadi, Xiaotong Yao, Cheng-Zhong Zhang, Jing Zhang, James E Haber, Asger Hobolth, Marcin Imielinski, Manolis Kellis, Michael S Lawrence, Christian von Mering, Hidewaki Nakagawa, Benjamin J Raphael, Mark A Rubin, Chris Sander, Lincoln D Stein, Joshua M Stuart, Tatsuhiko Tsunoda, David A Wheeler, Rory Johnson, Jüri Reimand, Mark Gerstein, Ekta Khurana, Peter J Campbell, Núria López-Bigas, PCAWG Drivers and Functional Interpretation Working Group, PCAWG Structural Variation Working Group, Joachim Weischenfeldt, Rameen Beroukhim, Iñigo Martincorena, Jakob Skou Pedersen, Gad Getz, PCAWG Consortium
Feb 04, 2021
The discovery of drivers of cancer has traditionally focused on protein-coding genes1-4. Here we present analyses of driver point mutations and structural variants in non-coding regions across 2,658 genomes from the Pan-Cancer...
Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis
Joana Carlevaro-Fita, Chen Hong, David Mas-Ponte, Jakob Skou Pedersen, Federico Abascal, Samirkumar B. Amin, Gary D. Bader, Jonathan Barenboim, Rameen Beroukhim, Johanna Bertl, Keith A. Boroevich, Søren Brunak, Peter J. Campbell, Dimple Chakravarty, Calvin Wing Yiu Chan, Ken Chen, Jung Kyoon Choi, Jordi Deu-Pons, Priyanka Dhingra, Klev Diamanti, Lars Feuerbach, J. Lynn Fink, Nuno A. Fonseca, Joan Frigola, Carlo Gambacorti-Passerini, Dale W. Garsed, Mark Gerstein, Gad Getz, Abel Gonzalez-Perez, Qianyun Guo, Ivo G. Gut, David Haan, Mark P. Hamilton, Nicholas J. Haradhvala, Arif O. Harmanci, Mohamed Helmy, Carl Herrmann, Julian M. Hess, Asger Hobolth, Ermin Hodzic, Henrik Hornshøj, Keren Isaev, Jose M. G. Izarzugaza, Rory Johnson, Todd A. Johnson, Malene Juul, Randi Istrup Juul, Andre Kahles, Abdullah Kahraman, Manolis Kellis, Ekta Khurana, Jaegil Kim, Jong K. Kim, Youngwook Kim, Jan Komorowski, Jan O. Korbel, Sushant Kumar, Andrés Lanzós, Erik Larsson, Michael S. Lawrence, Donghoon Lee, Kjong-Van Lehmann, Shantao Li, Xiaotong Li, Ziao Lin, Eric Minwei Liu, Lucas Lochovsky, Shaoke Lou, Tobias Madsen, Kathleen Marchal, Iñigo Martincorena, Alexander Martinez-Fundichely, Yosef E. Maruvka, Patrick D. McGillivray, William Meyerson, Ferran Muiños, Loris Mularoni, Hidewaki Nakagawa, Morten Muhlig Nielsen, Marta Paczkowska, Keunchil Park, Kiejung Park, Oriol Pich, Tirso Pons, Sergio Pulido-Tamayo, Benjamin J Raphael, Jüri Reimand, Iker Reyes-Salazar, Matthew A. Reyna, Esther Rheinbay, Mark A. Rubin, Carlota Rubio-Perez, Radhakrishnan Sabarinathan, S. Cenk Sahinalp, Gordon Saksena, Leonidas Salichos, Chris Sander, Steven E. Schumacher, Mark Shackleton, Ofer Shapira, Ciyue Shen, Raunak Shrestha, Shimin Shuai, Nikos Sidiropoulos, Lina Sieverling, Nasa Sinnott-Armstrong, Lincoln D. Stein, Joshua M. Stuart, David Tamborero, Grace Tiao, Tatsuhiko Tsunoda, Husen M. Umer, Liis Uusküla-Reimand, Alfonso Valencia, Miguel Vazquez, Lieven P. C. Verbeke, Claes Wadelius, Lina Wadi, Jiayin Wang, Jonathan Warrell, Sebastian M. Waszak, Joachim Weischenfeldt, David A. Wheeler, Guanming Wu, Jun Yu, Jing Zhang, Xuanping Zhang, Yan Zhang, Zhongming Zhao, Lihua Zou, Christian von Mering
Feb 04, 2021
Abstract: Long non-coding RNAs (lncRNAs) are a growing focus of cancer genomics studies, creating the need for a resource of lncRNAs with validated cancer roles. Furthermore, it remains debated whether mutated lncRNAs can drive...
SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion.
Petra Mlcochova, Steven A Kemp, Mahesh Shanker Dhar, Guido Papa, Bo Meng, Isabella ATM Ferreira, Rawlings Datir, Dami A Collier, Anna Albecka, Sujeet Singh, Rajesh Pandey, Jonathan Brown, Jie Zhou, Niluka Goonawardane, Swapnil Mishra, Charles Whittaker, Thomas Mellan, Robin Marwal, Meena Datta, Shantanu Sengupta, Kalaiarasan Ponnusamy, Venkatraman Srinivasan Radhakrishnan, Adam Abdullahi, Oscar Charles, Partha Chattopadhyay, Priti Devi, Daniela Caputo, Tom Peacock, Chand Wattal, Neeraj Goel, Ambrish Satwik, Raju Vaishya, Meenakshi Agarwal, Indian SARS-CoV-2 Genomics Consortium (INSACOG), Genotype to Phenotype Japan (G2P-Japan) Consortium, CITIID-NIHR BioResource COVID-19 Collaboration, Antranik Mavousian, Joo Hyeon Lee, Jessica Bassi, Chiara Silacci-Fegni, Christian Saliba, Dora Pinto, Takashi Irie, Isao Yoshida, William L Hamilton, Kei Sato, Samir Bhatt, Seth Flaxman, Leo C James, Davide Corti, Luca Piccoli, Wendy S Barclay, Partha Rakshit, Anurag Agrawal, Ravindra K Gupta
Sep 10, 2021
The B.1.617.2 (Delta) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first identified in the state of Maharashtra in late 2020 and spread throughout India, outcompeting pre-existing lineages...
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