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Comparison of Lactulose plus Rifaxamin versus Lactulose Alone For Hepatic Encephalopathy
Objective;Comparison of lactulose plus Rifaxamin versus lactulose alone for hepatic encephalopathy. Patients and methods:this was a randomized control trial conducted at Service Hospital, Lahore. In the present study, the cases...
Published by: IJHS Medical Association
Comparison of Lactulose plus Rifaxamin versus Lactulose Alone For Hepatic Encephalopathy
Objective;Comparison of lactulose plus Rifaxamin versus lactulose alone for hepatic encephalopathy. Patients and methods:this was a randomized control trial conducted at Service Hospital, Lahore. In the present study, the cases...
Published by: IJHS Medical Association
A Survey on Arabic Handwritten Script Recognition Systems
The optical character recognition (OCR) system is still an active research field in pattern recognition. Such systems can identify, recognize and distinguish electronically between characters and texts, printed or handwritten....
Genetic overlap between endometriosis and endometrial cancer
Epidemiological, biological, and molecular data suggest links between endometriosis and endometrial cancer, with recent epidemiological studies providing evidence for an association between a previous diagnosis of endometriosis...
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Genetic loci for retinal arteriolar microcirculation.
Narrow arterioles in the retina have been shown to predict hypertension as well as other vascular diseases, likely through an increase in the peripheral resistance of the microcirculatory flow. In this study, we performed a...
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Genetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist
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AEDGE
Yousef Abou El-Neaj, Cristiano Alpigiani, Sana Amairi-Pyka, Henrique Araújo, Antun Balaž, Angelo Bassi, Lars Bathe-Peters, Baptiste Battelier, Aleksandar Belić, Elliot Bentine, José Bernabeu, Andrea Bertoldi, Robert Bingham, Diego Blas, Vasiliki Bolpasi, Kai Bongs, Sougato Bose, Philippe Bouyer, Themis Bowcock, William Bowden, Oliver Buchmueller, Clare Burrage, Xavier Calmet, Benjamin Canuel, Laurentiu-Ioan Caramete, Andrew Carroll, Giancarlo Cella, Vassilis Charmandaris, Swapan Chattopadhyay, Xuzong Chen, Maria Luisa Chiofalo, Jonathon Coleman, Joseph Cotter, Yanou Cui, Andrei Derevianko, Albert De Roeck, Goran S. Djordjevic, Peter Dornan, Michael Doser, Ioannis Drougkakis, Jacob Dunningham, Ioana Dutan, Sajan Easo, Gedminas Elertas, John Ellis, Mai El Sawy, Farida Fassi, Daniel Felea, Chen-Hao Feng, Robert Flack, Chris Foot, Ivette Fuentes, Naceur Gaaloul, Alexandre Gauguet, Remi Geiger, Valerie Gibson, Gian Giudice, Jon Goldwin, Oleg Grachov, Peter W. Graham, Dario Grasso, Maurits van der Grinten, Mustafa Gündogan, Martin G. Haehnelt, Tiffany Harte, Aurélien Hees, Richard Hobson, Jason Hogan, Bodil Holst, Michael Holynski, Mark Kasevich, Bradley J. Kavanagh, Wolf von Klitzing, Tim Kovachy, Benjamin Krikler, Markus Krutzik, Marek Lewicki, Yu-Hung Lien, Miaoyuan Liu, Giuseppe Gaetano Luciano, Alain Magnon, Mohammed Attia Mahmoud, Sarah Malik, Christopher McCabe, Jeremiah Mitchell, Julia Pahl, Debapriya Pal, Saurabh Pandey, Dimitris Papazoglou, Mauro Paternostro, Bjoern Penning, Achim Peters, Marco Prevedelli, Vishnupriya Puthiya-Veettil, John Quenby, Ernst Rasel, Sean Ravenhall, Jack Ringwood, Albert Roura, Dylan Sabulsky, Muhammed Sameed, Ben Sauer, Stefan Alaric Schäffer, Stephan Schiller, Vladimir Schkolnik, Dennis Schlippert, Christian Schubert, Haifa Rejeb Sfar, Armin Shayeghi, Ian Shipsey, Carla Signorini, Yeshpal Singh, Marcelle Soares-Santos, Fiodor Sorrentino, Timothy Sumner, Konstantinos Tassis, Silvia Tentindo, Guglielmo Maria Tino, Jonathan N. Tinsley, James Unwin, Tristan Valenzuela, Georgios Vasilakis, Ville Vaskonen, Christian Vogt, Alex Webber-Date, André Wenzlawski, Patrick Windpassinger, Marian Woltmann, Efe Yazgan, Ming-Sheng Zhan, Xinhao Zou, Jure Zupan
Mar 04, 2021
Abstract: We propose in this White Paper a concept for a space experiment using cold atoms to search for ultra-light dark matter, and to detect gravitational waves in the frequency range between the most sensitive ranges of LISA...
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Mendelian randomization analyses suggest a role for cholesterol in the development of endometrial cancer.
Pik-Fang Kho, Frederic Amant, Daniela Annibali, Katie Ashton, John Attia, Paul L Auer, Matthias W Beckmann, Amanda Black, Louise Brinton, Daniel D Buchanan, Stephen J Chanock, Chu Chen, Maxine M Chen, Timothy Ht Cheng, Linda S Cook, Marta Crous-Bous, Kamila Czene, Immaculata De Vivo, Joe Dennis, Thilo Dörk, Sean C Dowdy, Alison M Dunning, Matthias Dürst, Douglas F Easton, Arif B Ekici, Peter A Fasching, Brooke L Fridley, Christine M Friedenreich, Montserrat García-Closas, Mia M Gaudet, Graham G Giles, Ellen L Goode, Maggie Gorman, Christopher A Haiman, Per Hall, Susan E Hankinson, Alexander Hein, Peter Hillemanns, Shirley Hodgson, Erling A Hoivik, Elizabeth G Holliday, David J Hunter, Angela Jones, Peter Kraft, Camilla Krakstad, Diether Lambrechts, Loic Le Marchand, Xiaolin Liang, Annika Lindblom, Jolanta Lissowska, Jirong Long, Lingeng Lu, Anthony M Magliocco, Lynn Martin, Mark McEvoy, Roger L Milne, Miriam Mints, Rami Nassir, Geoffrey Otton, Claire Palles, Loreall Pooler, Tony Proietto, Timothy R Rebbeck, Stefan P Renner, Harvey A Risch, Matthias Rübner, Ingo Runnebaum, Carlotta Sacerdote, Gloria E Sarto, Fredrick Schumacher, Rodney J Scott, V Wendy Setiawan, Mitul Shah, Xin Sheng, Xiao-Ou Shu, Melissa C Southey, Emma Tham, Ian Tomlinson, Jone Trovik, Constance Turman, Jonathan P Tyrer, David Van Den Berg, Zhaoming Wang, Nicolas Wentzensen, Lucy Xia, Yong-Bing Xiang, Hannah P Yang, Herbert Yu, Wei Zheng, Penelope M Webb, Deborah J Thompson, Amanda B Spurdle, Dylan M Glubb, Tracy A O'Mara
Sep 23, 2020
Blood lipids have been associated with the development of a range of cancers, including breast, lung and colorectal cancer. For endometrial cancer, observational studies have reported inconsistent associations between blood...
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Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer.
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AEDGE
Yousef Abou El-Neaj, Cristiano Alpigiani, Sana Amairi-Pyka, Henrique Araújo, Antun Balaž, Angelo Bassi, Lars Bathe-Peters, Baptiste Battelier, Aleksandar Belić, Elliot Bentine, José Bernabeu, Andrea Bertoldi, Robert Bingham, Diego Blas, Vasiliki Bolpasi, Kai Bongs, Sougato Bose, Philippe Bouyer, Themis Bowcock, William Bowden, Oliver Buchmueller, Clare Burrage, Xavier Calmet, Benjamin Canuel, Laurentiu-Ioan Caramete, Andrew Carroll, Giancarlo Cella, Vassilis Charmandaris, Swapan Chattopadhyay, Xuzong Chen, Maria Luisa Chiofalo, Jonathon Coleman, Joseph Cotter, Yanou Cui, Andrei Derevianko, Albert De Roeck, Goran S. Djordjevic, Peter Dornan, Michael Doser, Ioannis Drougkakis, Jacob Dunningham, Ioana Dutan, Sajan Easo, Gedminas Elertas, John Ellis, Mai El Sawy, Farida Fassi, Daniel Felea, Chen-Hao Feng, Robert Flack, Chris Foot, Ivette Fuentes, Naceur Gaaloul, Alexandre Gauguet, Remi Geiger, Valerie Gibson, Gian Giudice, Jon Goldwin, Oleg Grachov, Peter W. Graham, Dario Grasso, Maurits van der Grinten, Mustafa Gündogan, Martin G. Haehnelt, Tiffany Harte, Aurélien Hees, Richard Hobson, Jason Hogan, Bodil Holst, Michael Holynski, Mark Kasevich, Bradley J. Kavanagh, Wolf von Klitzing, Tim Kovachy, Benjamin Krikler, Markus Krutzik, Marek Lewicki, Yu-Hung Lien, Miaoyuan Liu, Giuseppe Gaetano Luciano, Alain Magnon, Mohammed Attia Mahmoud, Sarah Malik, Christopher McCabe, Jeremiah Mitchell, Julia Pahl, Debapriya Pal, Saurabh Pandey, Dimitris Papazoglou, Mauro Paternostro, Bjoern Penning, Achim Peters, Marco Prevedelli, Vishnupriya Puthiya-Veettil, John Quenby, Ernst Rasel, Sean Ravenhall, Jack Ringwood, Albert Roura, Dylan Sabulsky, Muhammed Sameed, Ben Sauer, Stefan Alaric Schäffer, Stephan Schiller, Vladimir Schkolnik, Dennis Schlippert, Christian Schubert, Haifa Rejeb Sfar, Armin Shayeghi, Ian Shipsey, Carla Signorini, Yeshpal Singh, Marcelle Soares-Santos, Fiodor Sorrentino, Timothy Sumner, Konstantinos Tassis, Silvia Tentindo, Guglielmo Maria Tino, Jonathan N. Tinsley, James Unwin, Tristan Valenzuela, Georgios Vasilakis, Ville Vaskonen, Christian Vogt, Alex Webber-Date, André Wenzlawski, Patrick Windpassinger, Marian Woltmann, Efe Yazgan, Ming-Sheng Zhan, Xinhao Zou, Jure Zupan
Jun 06, 2020
Abstract: We propose in this White Paper a concept for a space experiment using cold atoms to search for ultra-light dark matter, and to detect gravitational waves in the frequency range between the most sensitive ranges of LISA...
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CYP19A1 fine-mapping and Mendelian randomization
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Five endometrial cancer risk loci identified through genome-wide association analysis.
Timothy Ht Cheng, Deborah J Thompson, Tracy A O'Mara, Jodie N Painter, Dylan M Glubb, Susanne Flach, Annabelle Lewis, Juliet D French, Luke Freeman-Mills, David Church, Maggie Gorman, Lynn Martin, National Study of Endometrial Cancer Genetics Group (NSECG), Shirley Hodgson, Penelope M Webb, Australian National Endometrial Cancer Study Group (ANECS), John Attia, Elizabeth G Holliday, Mark McEvoy, Rodney J Scott, Anjali K Henders, Nicholas G Martin, Grant W Montgomery, Dale R Nyholt, Shahana Ahmed, Catherine S Healey, Mitul Shah, Joe Dennis, Peter A Fasching, Matthias W Beckmann, Alexander Hein, Arif B Ekici, Per Hall, Kamila Czene, Hatef Darabi, Jingmei Li, Thilo Dörk, Matthias Dürst, Peter Hillemanns, Ingo Runnebaum, Frederic Amant, Stefanie Schrauwen, Hui Zhao, Diether Lambrechts, Jeroen Depreeuw, Sean C Dowdy, Ellen L Goode, Brooke L Fridley, Stacey J Winham, Tormund S Njølstad, Helga B Salvesen, Jone Trovik, Henrica MJ Werner, Katie Ashton, Geoffrey Otton, Tony Proietto, Tao Liu, Miriam Mints, Emma Tham, RENDOCAS, Chibcha Consortium, Mulin Jun Li, Shun H Yip, Junwen Wang, Manjeet K Bolla, Kyriaki Michailidou, Qin Wang, Jonathan P Tyrer, Malcolm Dunlop, Richard Houlston, Claire Palles, John L Hopper, AOCS Group, Julian Peto, Anthony J Swerdlow, Barbara Burwinkel, Hermann Brenner, Alfons Meindl, Hiltrud Brauch, Annika Lindblom, Jenny Chang-Claude, Fergus J Couch, Graham G Giles, Vessela N Kristensen, Angela Cox, Julie M Cunningham, Paul DP Pharoah, Alison M Dunning, Stacey L Edwards, Douglas F Easton, Ian Tomlinson, Amanda B Spurdle
May 18, 2016
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1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.
Mathias Gorski, Peter J van der Most, Alexander Teumer, Audrey Y Chu, Man Li, Vladan Mijatovic, Ilja M Nolte, Massimiliano Cocca, Daniel Taliun, Felicia Gomez, Yong Li, Bamidele Tayo, Adrienne Tin, Mary F Feitosa, Thor Aspelund, John Attia, Reiner Biffar, Murielle Bochud, Eric Boerwinkle, Ingrid Borecki, Erwin P Bottinger, Ming-Huei Chen, Vincent Chouraki, Marina Ciullo, Josef Coresh, Marilyn C Cornelis, Gary C Curhan, Adamo Pio d'Adamo, Abbas Dehghan, Laura Dengler, Jingzhong Ding, Gudny Eiriksdottir, Karlhans Endlich, Stefan Enroth, Tõnu Esko, Oscar H Franco, Paolo Gasparini, Christian Gieger, Giorgia Girotto, Omri Gottesman, Vilmundur Gudnason, Ulf Gyllensten, Stephen J Hancock, Tamara B Harris, Catherine Helmer, Simon Höllerer, Edith Hofer, Albert Hofman, Elizabeth G Holliday, Georg Homuth, Frank B Hu, Cornelia Huth, Nina Hutri-Kähönen, Shih-Jen Hwang, Medea Imboden, Åsa Johansson, Mika Kähönen, Wolfgang König, Holly Kramer, Bernhard K Krämer, Ashish Kumar, Zoltan Kutalik, Jean-Charles Lambert, Lenore J Launer, Terho Lehtimäki, Martin de Borst, Gerjan Navis, Morris Swertz, Yongmei Liu, Kurt Lohman, Ruth JF Loos, Yingchang Lu, Leo-Pekka Lyytikäinen, Mark A McEvoy, Christa Meisinger, Thomas Meitinger, Andres Metspalu, Marie Metzger, Evelin Mihailov, Paul Mitchell, Matthias Nauck, Albertine J Oldehinkel, Matthias Olden, Brenda Wjh Penninx, Giorgio Pistis, Peter P Pramstaller, Nicole Probst-Hensch, Olli T Raitakari, Rainer Rettig, Paul M Ridker, Fernando Rivadeneira, Antonietta Robino, Sylvia E Rosas, Douglas Ruderfer, Daniela Ruggiero, Yasaman Saba, Cinzia Sala, Helena Schmidt, Reinhold Schmidt, Rodney J Scott, Sanaz Sedaghat, Albert V Smith, Rossella Sorice, Benedicte Stengel, Sylvia Stracke, Konstantin Strauch, Daniela Toniolo, Andre G Uitterlinden, Sheila Ulivi, Jorma S Viikari, Uwe Völker, Peter Vollenweider, Henry Völzke, Dragana Vuckovic, Melanie Waldenberger, Jie Jin Wang, Qiong Yang, Daniel I Chasman, Gerard Tromp, Harold Snieder, Iris M Heid, Caroline S Fox, Anna Köttgen, Cristian Pattaro, Carsten A Böger, Christian Fuchsberger
Nov 21, 2018
HapMap imputed genome-wide association studies (GWAS) have revealed >50 loci at which common variants with minor allele frequency >5% are associated with kidney function. GWAS using more complete reference sets for imputation...
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Genetic determinants of heel bone properties
Alireza Moayyeri, Yi-Hsiang Hsu, David Karasik, Karol Estrada, Su-Mei Xiao, Carrie Nielson, Priya Srikanth, Sylvie Giroux, Scott G Wilson, Hou-Feng Zheng, Albert V Smith, Stephen R Pye, Paul J Leo, Alexander Teumer, Joo-Yeon Hwang, Claes Ohlsson, Fiona McGuigan, Ryan L Minster, Caroline Hayward, José M Olmos, Leo-Pekka Lyytikäinen, Joshua R Lewis, Karin MA Swart, Laura Masi, Chris Oldmeadow, Elizabeth G Holliday, Sulin Cheng, Natasja M van Schoor, Nicholas C Harvey, Marcin Kruk, Fabiola del Greco M, Wilmar Igl, Olivia Trummer, Efi Grigoriou, Robert Luben, Ching-Ti Liu, Yanhua Zhou, Ling Oei, Carolina Medina-Gomez, Joseph Zmuda, Greg Tranah, Suzanne J Brown, Frances M Williams, Nicole Soranzo, Johanna Jakobsdottir, Kristin Siggeirsdottir, Kate L Holliday, Anke Hannemann, Min Jin Go, Melissa Garcia, Ozren Polasek, Marika Laaksonen, Kun Zhu, Anke W Enneman, Mark McEvoy, Roseanne Peel, Pak Chung Sham, Maciej Jaworski, Åsa Johansson, Andrew A Hicks, Pawel Pludowski, Rodney Scott, Rosalie AM Dhonukshe-Rutten, Nathalie van der Velde, Mika Kähönen, Jorma S Viikari, Harri Sievänen, Olli T Raitakari, Jesús González-Macías, Jose L Hernández, Dan Mellström, Osten Ljunggren, Yoon Shin Cho, Uwe Völker, Matthias Nauck, Georg Homuth, Henry Völzke, Robin Haring, Matthew A Brown, Eugene McCloskey, Geoffrey C Nicholson, Richard Eastell, John A Eisman, Graeme Jones, Ian R Reid, Elaine M Dennison, John Wark, Steven Boonen, Dirk Vanderschueren, Frederick CW Wu, Thor Aspelund, J Brent Richards, Doug Bauer, Albert Hofman, Kay-Tee Khaw, George Dedoussis, Barbara Obermayer-Pietsch, Ulf Gyllensten, Peter P Pramstaller, Roman S Lorenc, Cyrus Cooper, Annie Wai Chee Kung, Paul Lips, Markku Alen, John Attia, Maria Luisa Brandi, Lisette CPGM de Groot, Terho Lehtimäki, José A Riancho, Harry Campbell, Yongmei Liu, Tamara B Harris, Kristina Akesson, Magnus Karlsson, Jong-Young Lee, Henri Wallaschofski, Emma L Duncan, Terence W O'Neill, Vilmundur Gudnason, Timothy D Spector, François Rousseau, Eric Orwoll, Steven R Cummings, Nick J Wareham, Fernando Rivadeneira, Andre G Uitterlinden, Richard L Prince, Douglas P Kiel, Jonathan Reeve, Stephen K Kaptoge
Nov 12, 2014
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PCSK9 genetic variants and risk of type 2 diabetes
AF Schmidt, DI Swerdlow, MV Holmes, RS Patel, Z Fairhurst-Hunter, DM Lyall, FP Hartwig, BL Horta, E Hyppönen, C Power, M Moldovan, E van Iperen, GK Hovingh, I Demuth, K Norman, E Steinhagen-Thiessen, J Demuth, L Bertram, T Liu, S Coassin, J Willeit, S Kiechl, K Willeit, D Mason, J Wright, R Morris, G Wanamethee, P Whincup, Y Ben-Shlomo, S McLachlan, JF Price, M Kivimaki, C Welch, A Sanchez-Galvez, P Marques-Vidal, A Nicolaides, AG Panayiotou, NC Onland-Moret, YT van der Schouw, G Matullo, G Fiorito, S Guarrera, C Sacerdote, NJ Wareham, C Langenberg, R Scott, J Luan, M Bobak, S Malyutina, A Pająk, R Kubinova, A Tamosiunas, H Pikhart, LLN Husemoen, N Grarup, O Pedersen, T Hansen, A Linneberg, KS Simonsen, J Cooper, SE Humphries, M Brilliant, T Kitchner, H Hakonarson, DS Carrell, CA McCarty, HL Kirchner, EB Larson, DR Crosslin, M de Andrade, DM Roden, JC Denny, C Carty, S Hancock, J Attia, E Holliday, M O'Donnell, S Yusuf, M Chong, G Pare, P van der Harst, MA Said, RN Eppinga, N Verweij, H Snieder, LifeLines Cohort study group, T Christen, DO Mook-Kanamori, S Gustafsson, L Lind, E Ingelsson, R Pazoki, O Franco, A Hofman, A Uitterlinden, A Dehghan, A Teumer, S Baumeister, M Dörr, MM Lerch, U Völker, H Völzke, J Ward, JP Pell, DJ Smith, T Meade, AH Maitland-van der Zee, EV Baranova, R Young, I Ford, A Campbell, S Padmanabhan, ML Bots, DE Grobbee, P Froguel, D Thuillier, B Balkau, A Bonnefond, B Cariou, M Smart, Y Bao, M Kumari, A Mahajan, PM Ridker, DI Chasman, AP Reiner, LA Lange, MD Ritchie, FW Asselbergs, J-P Casas, BJ Keating, D Preiss, AD Hingorani, UCLEB Consortium, N Sattar
Feb 16, 2017
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Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.
Ayush Giri, Jacklyn N Hellwege, Jacob M Keaton, Jihwan Park, Chengxiang Qiu, Helen R Warren, Eric S Torstenson, Csaba P Kovesdy, Yan V Sun, Otis D Wilson, Cassianne Robinson-Cohen, Christianne L Roumie, Cecilia P Chung, Kelly A Birdwell, Scott M Damrauer, Scott L DuVall, Derek Klarin, Kelly Cho, Yu Wang, Evangelos Evangelou, Claudia P Cabrera, Louise V Wain, Rojesh Shrestha, Brian S Mautz, Elvis A Akwo, Muralidharan Sargurupremraj, Stéphanie Debette, Michael Boehnke, Laura J Scott, Jian'an Luan, Jing-Hua Zhao, Sara M Willems, Sébastien Thériault, Nabi Shah, Christopher Oldmeadow, Peter Almgren, Ruifang Li-Gao, Niek Verweij, Thibaud S Boutin, Massimo Mangino, Ioanna Ntalla, Elena Feofanova, Praveen Surendran, James P Cook, Savita Karthikeyan, Najim Lahrouchi, Chunyu Liu, Nuno Sepúlveda, Tom G Richardson, Aldi Kraja, Philippe Amouyel, Martin Farrall, Neil R Poulter, Understanding Society Scientific Group, International Consortium for Blood Pressure, Blood Pressure-International Consortium of Exome Chip Studies, Markku Laakso, Eleftheria Zeggini, Peter Sever, Robert A Scott, Claudia Langenberg, Nicholas J Wareham, David Conen, Colin Neil Alexander Palmer, John Attia, Daniel I Chasman, Paul M Ridker, Olle Melander, Dennis Owen Mook-Kanamori, Pim van der Harst, Francesco Cucca, David Schlessinger, Caroline Hayward, Tim D Spector, Marjo-Riitta Jarvelin, Branwen J Hennig, Nicholas J Timpson, Wei-Qi Wei, Joshua C Smith, Yaomin Xu, Michael E Matheny, Edward E Siew, Cecilia Lindgren, Karl-Heinz Herzig, George Dedoussis, Joshua C Denny, Bruce M Psaty, Joanna MM Howson, Patricia B Munroe, Christopher Newton-Cheh, Mark J Caulfield, Paul Elliott, J Michael Gaziano, John Concato, Peter WF Wilson, Philip S Tsao, Digna R Velez Edwards, Katalin Susztak, Million Veteran Program, Christopher J O'Donnell, Adriana M Hung, Todd L Edwards
Feb 01, 2019
In this trans-ethnic multi-omic study, we reinterpret the genetic architecture of blood pressure to identify genes, tissues, phenomes and medication contexts of blood pressure homeostasis. We discovered 208 novel common blood...
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Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk.
Jodie N Painter, Tracy A O'Mara, Jyotsna Batra, Timothy Cheng, Felicity A Lose, Joe Dennis, Kyriaki Michailidou, Jonathan P Tyrer, Shahana Ahmed, Kaltin Ferguson, Catherine S Healey, Susanne Kaufmann, Kristine M Hillman, Carina Walpole, Leire Moya, Pamela Pollock, Angela Jones, Kimberley Howarth, Lynn Martin, Maggie Gorman, Shirley Hodgson, National Study of Endometrial Cancer Genetics Group (NSECG), CHIBCHA Consortium, Ma Magdalena Echeverry De Polanco, Monica Sans, Angel Carracedo, Sergi Castellvi-Bel, Augusto Rojas-Martinez, Erika Santos, Manuel R Teixeira, Luis Carvajal-Carmona, Xiao-Ou Shu, Jirong Long, Wei Zheng, Yong-Bing Xiang, Australian National Endometrial Cancer Study Group (ANECS), Grant W Montgomery, Penelope M Webb, Rodney J Scott, Mark McEvoy, John Attia, Elizabeth Holliday, Nicholas G Martin, Dale R Nyholt, Anjali K Henders, Peter A Fasching, Alexander Hein, Matthias W Beckmann, Stefan P Renner, Thilo Dörk, Peter Hillemanns, Matthias Dürst, Ingo Runnebaum, Diether Lambrechts, Lieve Coenegrachts, Stefanie Schrauwen, Frederic Amant, Boris Winterhoff, Sean C Dowdy, Ellen L Goode, Attila Teoman, Helga B Salvesen, Jone Trovik, Tormund S Njolstad, Henrica MJ Werner, Katie Ashton, Tony Proietto, Geoffrey Otton, Gerasimos Tzortzatos, Miriam Mints, Emma Tham, RENDOCAS, Per Hall, Kamila Czene, Jianjun Liu, Jingmei Li, John L Hopper, Melissa C Southey, Australian Ovarian Cancer Study (AOCS), Arif B Ekici, Matthias Ruebner, Nicola Johnson, Julian Peto, Barbara Burwinkel, Frederik Marme, Hermann Brenner, Aida K Dieffenbach, Alfons Meindl, Hiltrud Brauch, GENICA Network, Annika Lindblom, Jeroen Depreeuw, Matthieu Moisse, Jenny Chang-Claude, Anja Rudolph, Fergus J Couch, Janet E Olson, Graham G Giles, Fiona Bruinsma, Julie M Cunningham, Brooke L Fridley, Anne-Lise Børresen-Dale, Vessela N Kristensen, Angela Cox, Anthony J Swerdlow, Nicholas Orr, Manjeet K Bolla, Qin Wang, Rachel Palmieri Weber, Zhihua Chen, Mitul Shah, Juliet D French, Paul DP Pharoah, Alison M Dunning, Ian Tomlinson, Douglas F Easton, Stacey L Edwards, Deborah J Thompson, Amanda B Spurdle
Feb 12, 2015
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Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.
Gail Davies, Max Lam, Sarah E Harris, Joey W Trampush, Michelle Luciano, W David Hill, Saskia P Hagenaars, Stuart J Ritchie, Riccardo E Marioni, Chloe Fawns-Ritchie, David Cm Liewald, Judith A Okely, Ari V Ahola-Olli, Catriona LK Barnes, Lars Bertram, Joshua C Bis, Katherine E Burdick, Andrea Christoforou, Pamela DeRosse, Srdjan Djurovic, Thomas Espeseth, Stella Giakoumaki, Sudheer Giddaluru, Daniel E Gustavson, Caroline Hayward, Edith Hofer, M Arfan Ikram, Robert Karlsson, Emma Knowles, Jari Lahti, Markus Leber, Shuo Li, Karen A Mather, Ingrid Melle, Derek Morris, Christopher Oldmeadow, Teemu Palviainen, Antony Payton, Raha Pazoki, Katja Petrovic, Chandra A Reynolds, Muralidharan Sargurupremraj, Markus Scholz, Jennifer A Smith, Albert V Smith, Natalie Terzikhan, Anbupalam Thalamuthu, Stella Trompet, Sven J van der Lee, Erin B Ware, B Gwen Windham, Margaret J Wright, Jingyun Yang, Jin Yu, David Ames, Najaf Amin, Philippe Amouyel, Ole A Andreassen, Nicola J Armstrong, Amelia A Assareh, John R Attia, Deborah Attix, Dimitrios Avramopoulos, David A Bennett, Anne C Böhmer, Patricia A Boyle, Henry Brodaty, Harry Campbell, Tyrone D Cannon, Elizabeth T Cirulli, Eliza Congdon, Emily Drabant Conley, Janie Corley, Simon R Cox, Anders M Dale, Abbas Dehghan, Danielle Dick, Dwight Dickinson, Johan G Eriksson, Evangelos Evangelou, Jessica D Faul, Ian Ford, Nelson A Freimer, He Gao, Ina Giegling, Nathan A Gillespie, Scott D Gordon, Rebecca F Gottesman, Michael E Griswold, Vilmundur Gudnason, Tamara B Harris, Annette M Hartmann, Alex Hatzimanolis, Gerardo Heiss, Elizabeth G Holliday, Peter K Joshi, Mika Kähönen, Sharon LR Kardia, Ida Karlsson, Luca Kleineidam, David S Knopman, Nicole A Kochan, Bettina Konte, John B Kwok, Stephanie Le Hellard, Teresa Lee, Terho Lehtimäki, Shu-Chen Li, Tian Liu, Marisa Koini, Edythe London, Will T Longstreth, Oscar L Lopez, Anu Loukola, Tobias Luck, Astri J Lundervold, Anders Lundquist, Leo-Pekka Lyytikäinen, Nicholas G Martin, Grant W Montgomery, Alison D Murray, Anna C Need, Raymond Noordam, Lars Nyberg, William Ollier, Goran Papenberg, Alison Pattie, Ozren Polasek, Russell A Poldrack, Bruce M Psaty, Simone Reppermund, Steffi G Riedel-Heller, Richard J Rose, Jerome I Rotter, Panos Roussos, Suvi P Rovio, Yasaman Saba, Fred W Sabb, Perminder S Sachdev, Claudia L Satizabal, Matthias Schmid, Rodney J Scott, Matthew A Scult, Jeannette Simino, P Eline Slagboom, Nikolaos Smyrnis, Aïcha Soumaré, Nikos C Stefanis, David J Stott, Richard E Straub, Kjetil Sundet, Adele M Taylor, Kent D Taylor, Ioanna Tzoulaki, Christophe Tzourio, André Uitterlinden, Veronique Vitart, Aristotle N Voineskos, Jaakko Kaprio, Michael Wagner, Holger Wagner, Leonie Weinhold, K Hoyan Wen, Elisabeth Widen, Qiong Yang, Wei Zhao, Hieab HH Adams, Dan E Arking, Robert M Bilder, Panos Bitsios, Eric Boerwinkle, Ornit Chiba-Falek, Aiden Corvin, Philip L De Jager, Stéphanie Debette, Gary Donohoe, Paul Elliott, Annette L Fitzpatrick, Michael Gill, David C Glahn, Sara Hägg, Narelle K Hansell, Ahmad R Hariri, M Kamran Ikram, J Wouter Jukema, Eero Vuoksimaa, Matthew C Keller, William S Kremen, Lenore Launer, Ulman Lindenberger, Aarno Palotie, Nancy L Pedersen, Neil Pendleton, David J Porteous, Katri Räikkönen, Olli T Raitakari, Alfredo Ramirez, Ivar Reinvang, Igor Rudan, Dan Rujescu, Reinhold Schmidt, Helena Schmidt, Peter W Schofield, Peter R Schofield, John M Starr, Vidar M Steen, Julian N Trollor, Steven T Turner, Cornelia M van Duijn, Arno Villringer, Daniel R Weinberger, David R Weir, James F Wilson, Anil Malhotra, Andrew M McIntosh, Catharine R Gale, Sudha Seshadri, Thomas H Mosley, Jan Bressler, Todd Lencz, Ian J Deary
Sep 24, 2018
General cognitive function is a prominent and relatively stable human trait that is associated with many important life outcomes. We combine cognitive and genetic data from the CHARGE and COGENT consortia, and UK Biobank (total...
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