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Disaster displacement and zoonotic disease dynamics
Projected increases in human and animal displacement driven by climate change, disasters and related environmental degradation will have significant implications to global health. Pathways for infectious disease transmission...
Published by: PLOS global public health
Serviceability of non-prismatic concrete beams
Interest in the shape optimisation of concrete members is increasing alongside the availability of fabric formwork as a relatively simple technique to cast non-prismatic concrete structures. Research has shown that up 40% of...
Ultrasound Promoted Synthesis and Properties of Chitosan Nanocomposites Containing Carbon Nanotubes and Silver Nanoparticles
A rapid and facile method to prepare functional chitosan nanocomposite films incorporating silver nanoparticles (AgNPs) has been developed using ultrasound assisted in-situ synthesis, dispersion and crosslinking. Addition of...
The Role of Educational Technology in Academia
The subject of study known as educational technology examines the process of examining, creating, developing, implementing, and evaluating the instructional environment, learning materials, students, and the learning process in...
Global Information Technology Computer Science and Information Technology Global Information Technology Physical Sciences and Engineering Business and Management
Published by: IGI Global Scientific Publishing
Ultrasound Promoted Synthesis and Properties of Chitosan Nanocomposites Containing Carbon Nanotubes and Silver Nanoparticles
A rapid and facile method to prepare functional chitosan nanocomposite films incorporating silver nanoparticles (AgNPs) has been developed using ultrasound assisted in-situ synthesis, dispersion and crosslinking. Addition of...
Serviceability of non-prismatic concrete beams
Interest in the shape optimisation of concrete members is increasing alongside the availability of fabric formwork as a relatively simple technique to cast non-prismatic concrete structures. Research has shown that up 40% of...
An SOI CMOS-Based Multi-Sensor MEMS Chip for Fluidic Applications.
Mohtashim Mansoor, Ibraheem Haneef, Suhail Akhtar, Muhammad Aftab Rafiq, Andrea De Luca, Syed Zeeshan Ali, Florin Udrea
Dec 13, 2018
An SOI CMOS multi-sensor MEMS chip, which can simultaneously measure temperature, pressure and flow rate, has been reported. The multi-sensor chip has been designed keeping in view the requirements of researchers interested in...
Allergic disease, corticosteroid use, and risk of Hodgkin lymphoma
Meena Rafiq, Andrew Hayward, Charlotte Warren-Gash, Spiros Denaxas, Arturo Gonzalez-Izquierdo, Georgios Lyratzopoulos, Sara Thomas
Feb 07, 2020
BACKGROUND: Immunodeficiency syndromes (acquired/congenital/iatrogenic) are known to increase Hodgkin lymphoma (HL) risk, but the effects of allergic immune dysregulation and corticosteroids are poorly understood. OBJECTIVE: We...
allergic disease Hodgkin lymphoma allergic rhinitis Asthma Atopic dermatitis corticosteroids eczema risk Adolescent Adrenal Cortex Hormones Adult Case-Control Studies Child Child Preschool Female Hodgkin Disease Humans Hypersensitivity Immediate Immunocompromised Host Immunosuppressive Agents Male United Kingdom Young Adult
Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy.
J Lei, A Rudolph, KB Moysich, S Rafiq, S Behrens, EL Goode, PD Pharoah, P Seibold, PA Fasching, IL Andrulis, VN Kristensen, FJ Couch, U Hamann, MJ Hooning, H Nevanlinna, U Eilber, MK Bolla, J Dennis, Q Wang, A Lindblom, A Mannermaa, D Lambrechts, M García-Closas, P Hall, G Chenevix-Trench, M Shah, R Luben, L Haeberle, AB Ekici, MW Beckmann, JA Knight, G Glendon, S Tchatchou, GI Alnæs, AL Borresen-Dale, S Nord, JE Olson, E Hallberg, C Vachon, D Torres, HU Ulmer, T Rüdiger, A Jager, CH van Deurzen, MM Tilanus-Linthorst, TA Muranen, K Aittomäki, C Blomqvist, S Margolin, VM Kosma, JM Hartikainen, V Kataja, S Hatse, H Wildiers, A Smeets, J Figueroa, SJ Chanock, J Lissowska, J Li, K Humphreys, KA Phillips, kConFab Investigators, S Linn, S Cornelissen, SA van den Broek, D Kang, JY Choi, SK Park, KY Yoo, CN Hsiung, PE Wu, MF Hou, CY Shen, SH Teo, NA Taib, CH Yip, GF Ho, K Matsuo, H Ito, H Iwata, K Tajima, AM Dunning, J Benitez, K Czene, LE Sucheston, T Maishman, WJ Tapper, D Eccles, DF Easton, MK Schmidt, J Chang-Claude
Jun 17, 2019
Breast Cancer Genetics Cancer 2.1 Biological and endogenous factors 2 Aetiology 4.2 Evaluation of markers and technologies 4 Detection screening and diagnosis Cancer Adult Antineoplastic Combined Chemotherapy Protocols Biomarkers Tumor Breast Neoplasms Female Genomics Humans immunomodulation Interleukin-12 Subunit p40 Kaplan-Meier Estimate Middle Aged Neoplasm Grading Neoplasm Staging Polymorphism Single Nucleotide Prognosis Protein Serine-Threonine Kinases Receptor Transforming Growth Factor-beta Type II Receptors Estrogen Receptors Transforming Growth Factor beta Signal Transduction Treatment Outcome Tumor Burden
2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy.
Jingmei Li, Linda S Lindström, Jia N Foo, Sajjad Rafiq, Marjanka K Schmidt, Paul DP Pharoah, Kyriaki Michailidou, Joe Dennis, Manjeet K Bolla, Qin Wang, Laura J van 't Veer, Sten Cornelissen, Emiel Rutgers, Melissa C Southey, Carmel Apicella, Gillian S Dite, John L Hopper, Peter A Fasching, Lothar Haeberle, Arif B Ekici, Matthias W Beckmann, Carl Blomqvist, Taru A Muranen, Kristiina Aittomäki, Annika Lindblom, Sara Margolin, Arto Mannermaa, Veli-Matti Kosma, Jaana M Hartikainen, Vesa Kataja, Georgia Chenevix-Trench, kConFab Investigators, Kelly-Anne Phillips, Sue-Anne McLachlan, Diether Lambrechts, Bernard Thienpont, Ann Smeets, Hans Wildiers, Jenny Chang-Claude, Dieter Flesch-Janys, Petra Seibold, Anja Rudolph, Graham G Giles, Laura Baglietto, Gianluca Severi, Christopher A Haiman, Brian E Henderson, Fredrick Schumacher, Loic Le Marchand, Vessela Kristensen, Grethe I Grenaker Alnaes, Anne-Lise Borresen-Dale, Silje Nord, Robert Winqvist, Katri Pylkäs, Arja Jukkola-Vuorinen, Mervi Grip, Irene L Andrulis, Julia A Knight, Gord Glendon, Sandrine Tchatchou, Peter Devilee, Robert Tollenaar, Caroline Seynaeve, Maartje Hooning, Mieke Kriege, Antoinette Hollestelle, Ans van den Ouweland, Yi Li, Ute Hamann, Diana Torres, Hans U Ulmer, Thomas Rüdiger, Chen-Yang Shen, Chia-Ni Hsiung, Pei-Ei Wu, Shou-Tung Chen, Soo Hwang Teo, Nur Aishah Mohd Taib, Cheng Har Yip, Gwo Fuang Ho, Keitaro Matsuo, Hidemi Ito, Hiroji Iwata, Kazuo Tajima, Daehee Kang, Ji-Yeob Choi, Sue K Park, Keun-Young Yoo, Tom Maishman, William J Tapper, Alison Dunning, Mitul Shah, Robert Luben, Judith Brown, Chiea Chuen Khor, Diana M Eccles, Heli Nevanlinna, Douglas Easton, Keith Humphreys, Jianjun Liu, Per Hall, Kamila Czene
Sep 10, 2018
Large population-based registry studies have shown that breast cancer prognosis is inherited. Here we analyse single-nucleotide polymorphisms (SNPs) of genes implicated in human immunology and inflammation as candidates for...
Prediction of breast cancer risk based on profiling with common genetic variants.
Nasim Mavaddat, Paul DP Pharoah, Kyriaki Michailidou, Jonathan Tyrer, Mark N Brook, Manjeet K Bolla, Qin Wang, Joe Dennis, Alison M Dunning, Mitul Shah, Robert Luben, Judith Brown, Stig E Bojesen, Børge G Nordestgaard, Sune F Nielsen, Henrik Flyger, Kamila Czene, Hatef Darabi, Mikael Eriksson, Julian Peto, Isabel dos-Santos-Silva, Frank Dudbridge, Nichola Johnson, Marjanka K Schmidt, Annegien Broeks, Senno Verhoef, Emiel J Rutgers, Anthony Swerdlow, Alan Ashworth, Nick Orr, Minouk J Schoemaker, Jonine Figueroa, Stephen J Chanock, Louise Brinton, Jolanta Lissowska, Fergus J Couch, Janet E Olson, Celine Vachon, Vernon S Pankratz, Diether Lambrechts, Hans Wildiers, Chantal Van Ongeval, Erik van Limbergen, Vessela Kristensen, Grethe Grenaker Alnæs, Silje Nord, Anne-Lise Borresen-Dale, Heli Nevanlinna, Taru A Muranen, Kristiina Aittomäki, Carl Blomqvist, Jenny Chang-Claude, Anja Rudolph, Petra Seibold, Dieter Flesch-Janys, Peter A Fasching, Lothar Haeberle, Arif B Ekici, Matthias W Beckmann, Barbara Burwinkel, Frederik Marme, Andreas Schneeweiss, Christof Sohn, Amy Trentham-Dietz, Polly Newcomb, Linda Titus, Kathleen M Egan, David J Hunter, Sara Lindstrom, Rulla M Tamimi, Peter Kraft, Nazneen Rahman, Clare Turnbull, Anthony Renwick, Sheila Seal, Jingmei Li, Jianjun Liu, Keith Humphreys, Javier Benitez, M Pilar Zamora, Jose Ignacio Arias Perez, Primitiva Menéndez, Anna Jakubowska, Jan Lubinski, Katarzyna Jaworska-Bieniek, Katarzyna Durda, Natalia V Bogdanova, Natalia N Antonenkova, Thilo Dörk, Hoda Anton-Culver, Susan L Neuhausen, Argyrios Ziogas, Leslie Bernstein, Peter Devilee, Robert AEM Tollenaar, Caroline Seynaeve, Christi J van Asperen, Angela Cox, Simon S Cross, Malcolm Wr Reed, Elza Khusnutdinova, Marina Bermisheva, Darya Prokofyeva, Zalina Takhirova, Alfons Meindl, Rita K Schmutzler, Christian Sutter, Rongxi Yang, Peter Schürmann, Michael Bremer, Hans Christiansen, Tjoung-Won Park-Simon, Peter Hillemanns, Pascal Guénel, Thérèse Truong, Florence Menegaux, Marie Sanchez, Paolo Radice, Paolo Peterlongo, Siranoush Manoukian, Valeria Pensotti, John L Hopper, Helen Tsimiklis, Carmel Apicella, Melissa C Southey, Hiltrud Brauch, Thomas Brüning, Yon-Dschun Ko, Alice J Sigurdson, Michele M Doody, Ute Hamann, Diana Torres, Hans-Ulrich Ulmer, Asta Försti, Elinor J Sawyer, Ian Tomlinson, Michael J Kerin, Nicola Miller, Irene L Andrulis, Julia A Knight, Gord Glendon, Anna Marie Mulligan, Georgia Chenevix-Trench, Rosemary Balleine, Graham G Giles, Roger L Milne, Catriona Mclean, Annika Lindblom, Sara Margolin, Christopher A Haiman, Brian E Henderson, Fredrick Schumacher, Loic Le Marchand, Ursula Eilber, Shan Wang-Gohrke, Maartje J Hooning, Antoinette Hollestelle, Ans Mw van den Ouweland, Linetta B Koppert, Jane Carpenter, Christine Clarke, Rodney Scott, Arto Mannermaa, Vesa Kataja, Veli-Matti Kosma, Jaana M Hartikainen, Hermann Brenner, Volker Arndt, Christa Stegmaier, Aida Karina Dieffenbach, Robert Winqvist, Katri Pylkäs, Arja Jukkola-Vuorinen, Mervi Grip, Kenneth Offit, Joseph Vijai, Mark Robson, Rohini Rau-Murthy, Miriam Dwek, Ruth Swann, Katherine Annie Perkins, Mark S Goldberg, France Labrèche, Martine Dumont, Diana M Eccles, William J Tapper, Sajjad Rafiq, Esther M John, Alice S Whittemore, Susan Slager, Drakoulis Yannoukakos, Amanda E Toland, Song Yao, Wei Zheng, Sandra L Halverson, Anna González-Neira, Guillermo Pita, M Rosario Alonso, Nuria Álvarez, Daniel Herrero, Daniel C Tessier, Daniel Vincent, Francois Bacot, Craig Luccarini, Caroline Baynes, Shahana Ahmed, Mel Maranian, Catherine S Healey, Jacques Simard, Per Hall, Douglas F Easton, Montserrat Garcia-Closas
May 14, 2015
Adult Aged Biomarkers Tumor Breast Neoplasms Europe Female Gene Expression Profiling Gene Expression Regulation Neoplastic Genetic Predisposition to Disease Genotype Humans Middle Aged Odds Ratio Polymorphism Single Nucleotide Predictive Value of Tests Receptors Estrogen Risk Assessment Risk Factors
PALB2, CHEK2 and ATM rare variants and cancer risk
Melissa C Southey, David E Goldgar, Robert Winqvist, Katri Pylkäs, Fergus Couch, Marc Tischkowitz, William D Foulkes, Joe Dennis, Kyriaki Michailidou, Elizabeth J van Rensburg, Tuomas Heikkinen, Heli Nevanlinna, John L Hopper, Thilo Dörk, Kathleen BM Claes, Jorge Reis-Filho, Zhi Ling Teo, Paolo Radice, Irene Catucci, Paolo Peterlongo, Helen Tsimiklis, Fabrice A Odefrey, James G Dowty, Marjanka K Schmidt, Annegien Broeks, Frans B Hogervorst, Senno Verhoef, Jane Carpenter, Christine Clarke, Rodney J Scott, Peter A Fasching, Lothar Haeberle, Arif B Ekici, Matthias W Beckmann, Julian Peto, Isabel dos-Santos-Silva, Olivia Fletcher, Nichola Johnson, Manjeet K Bolla, Elinor J Sawyer, Ian Tomlinson, Michael J Kerin, Nicola Miller, Federik Marme, Barbara Burwinkel, Rongxi Yang, Pascal Guénel, Thérèse Truong, Florence Menegaux, Marie Sanchez, Stig Bojesen, Sune F Nielsen, Henrik Flyger, Javier Benitez, M Pilar Zamora, Jose Ignacio Arias Perez, Primitiva Menéndez, Hoda Anton-Culver, Susan Neuhausen, Argyrios Ziogas, Christina A Clarke, Hermann Brenner, Volker Arndt, Christa Stegmaier, Hiltrud Brauch, Thomas Brüning, Yon-Dschun Ko, Taru A Muranen, Kristiina Aittomäki, Carl Blomqvist, Natalia V Bogdanova, Natalia N Antonenkova, Annika Lindblom, Sara Margolin, Arto Mannermaa, Vesa Kataja, Veli-Matti Kosma, Jaana M Hartikainen, Amanda B Spurdle, KConFaB Investigators, Australian Ovarian Cancer Study Group, Els Wauters, Dominiek Smeets, Benoit Beuselinck, Giuseppe Floris, Jenny Chang-Claude, Anja Rudolph, Petra Seibold, Dieter Flesch-Janys, Janet E Olson, Celine Vachon, Vernon S Pankratz, Catriona Mclean, Christopher A Haiman, Brian E Henderson, Fredrick Schumacher, Loic Le Marchand, Vessela Kristensen, Grethe Grenaker Alnæs, Wei Zheng, David J Hunter, Sara Lindstrom, Susan E Hankinson, Peter Kraft, Irene Andrulis, Julia A Knight, Gord Glendon, Anna Marie Mulligan, Arja Jukkola-Vuorinen, Mervi Grip, Saila Kauppila, Peter Devilee, Robert AEM Tollenaar, Caroline Seynaeve, Antoinette Hollestelle, Montserrat Garcia-Closas, Jonine Figueroa, Stephen J Chanock, Jolanta Lissowska, Kamila Czene, Hatef Darabi, Mikael Eriksson, Diana M Eccles, Sajjad Rafiq, William J Tapper, Sue M Gerty, Maartje J Hooning, John WM Martens, J Margriet Collée, Madeleine Tilanus-Linthorst, Per Hall, Jingmei Li, Judith S Brand, Keith Humphreys, Angela Cox, Malcolm Wr Reed, Craig Luccarini, Caroline Baynes, Alison M Dunning, Ute Hamann, Diana Torres, Hans Ulrich Ulmer, Thomas Rüdiger, Anna Jakubowska, Jan Lubinski, Katarzyna Jaworska, Katarzyna Durda, Susan Slager, Amanda E Toland, Christine B Ambrosone, Drakoulis Yannoukakos, Anthony Swerdlow, Alan Ashworth, Nick Orr, Michael Jones, Anna González-Neira, Guillermo Pita, M Rosario Alonso, Nuria Álvarez, Daniel Herrero, Daniel C Tessier, Daniel Vincent, Francois Bacot, Jacques Simard, Martine Dumont, Penny Soucy, Rosalind Eeles, Kenneth Muir, Fredrik Wiklund, Henrik Gronberg, Johanna Schleutker, Børge G Nordestgaard, Maren Weischer, Ruth C Travis, David Neal, Jenny L Donovan, Freddie C Hamdy, Kay-Tee Khaw, Janet L Stanford, William J Blot, Stephen Thibodeau, Daniel J Schaid, Joseph L Kelley, Christiane Maier, Adam S Kibel, Cezary Cybulski, Lisa Cannon-Albright, Katja Butterbach, Jong Park, Radka Kaneva, Jyotsna Batra, Manuel R Teixeira, Zsofia Kote-Jarai, Ali Amin Al Olama, Sara Benlloch, Stefan P Renner, Arndt Hartmann, Alexander Hein, Matthias Ruebner, Diether Lambrechts, Els Van Nieuwenhuysen, Ignace Vergote, Sandrina Lambretchs, Jennifer A Doherty, Mary Anne Rossing, Stefan Nickels, Ursula Eilber, Shan Wang-Gohrke, Kunle Odunsi, Lara E Sucheston-Campbell, Grace Friel, Galina Lurie, Jeffrey L Killeen, Lynne R Wilkens, Marc T Goodman, Ingo Runnebaum, Peter A Hillemanns, Liisa M Pelttari, Ralf Butzow, Francesmary Modugno, Robert P Edwards, Roberta B Ness, Kirsten B Moysich, Andreas du Bois, Florian Heitz, Philipp Harter, Stefan Kommoss, Beth Y Karlan, Christine Walsh, Jenny Lester, Allan Jensen, Susanne Krüger Kjær, Estrid Høgdall, Bernard Peissel, Bernardo Bonanni, Loris Bernard, Ellen L Goode, Brooke L Fridley, Robert A Vierkant, Julie M Cunningham, Melissa C Larson, Zachary C Fogarty, Kimberly R Kalli, Dong Liang, Karen H Lu, Michelle AT Hildebrandt, Xifeng Wu, Douglas A Levine, Fanny Dao, Maria Bisogna, Andrew Berchuck, Edwin S Iversen, Jeffrey R Marks, Lucy Akushevich, Daniel W Cramer, Joellen Schildkraut, Kathryn L Terry, Elizabeth M Poole, Meir Stampfer, Shelley S Tworoger, Elisa V Bandera, Irene Orlow, Sara H Olson, Line Bjorge, Helga B Salvesen, Anne M van Altena, Katja KH Aben, Lambertus A Kiemeney, Leon FAG Massuger, Tanja Pejovic, Yukie Bean, Angela Brooks-Wilson, Linda E Kelemen, Linda S Cook, Nhu D Le, Bohdan Górski, Jacek Gronwald, Janusz Menkiszak, Claus K Høgdall, Lene Lundvall, Lotte Nedergaard, Svend Aage Engelholm, Ed Dicks, Jonathan Tyrer, Ian Campbell, Iain McNeish, James Paul, Nadeem Siddiqui, Rosalind Glasspool, Alice S Whittemore, Joseph H Rothstein, Valerie McGuire, Weiva Sieh, Hui Cai, Xiao-Ou Shu, Rachel T Teten, Rebecca Sutphen, John R McLaughlin, Steven A Narod, Catherine M Phelan, Alvaro N Monteiro, David Fenstermacher, Hui-Yi Lin, Jennifer B Permuth, Thomas A Sellers, Y Ann Chen, Ya-Yu Tsai, Zhihua Chen, Aleksandra Gentry-Maharaj, Simon A Gayther, Susan J Ramus, Usha Menon, Anna H Wu, Celeste L Pearce, David Van Den Berg, Malcolm C Pike, Agnieszka Dansonka-Mieszkowska, Joanna Plisiecka-Halasa, Joanna Moes-Sosnowska, Jolanta Kupryjanczyk, Paul DP Pharoah, Honglin Song, Ingrid Winship, Georgia Chenevix-Trench, Graham G Giles, Sean V Tavtigian, Doug F Easton, Roger L Milne
Aug 17, 2016
Cancer: breast Cancer: ovary Cancer: prostate Genetics cancer predisposition Ataxia Telangiectasia Mutated Proteins Breast Neoplasms Case-Control Studies Checkpoint Kinase 2 Fanconi Anemia Complementation Group N Protein Female Genetic Association Studies Genetic Predisposition to Disease Humans Male Mutation Nuclear Proteins Ovarian Neoplasms Prostatic Neoplasms risk Tumor Suppressor Proteins