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The decrease in silicon concentration of the connective tissues with age in rats is a marker of connective tissue turnover.
Silicon may be important for bone and connective tissue health. Higher concentrations of silicon are suggested to be associated with bone and the connective tissues, compared with the non-connective soft tissues. Moreover, in...
High-aluminum-affinity silica is a nanoparticle that seeds secondary aluminosilicate formation.
Despite the importance and abundance of aluminosilicates throughout our natural surroundings, their formation at neutral pH is, surprisingly, a matter of considerable debate. From our experiments in dilute aluminum and silica...
Silicon balance in human volunteers; a pilot study to establish the variance in silicon excretion versus intake.
BACKGROUND: Accumulating evidence suggests a role for silicon in optimal connective tissue health. Further proof of its importance/essentiality may be provided by studies involving imposed depletion followed by 29Si challenge to...
Silica nanoparticles as sources of silicic acid favoring wound healing in vitro.
There is good evidence that certain silicon-containing materials promote would healing and their common feature is the delivery of orthosilicic acid (Si(OH)4) either directly or following metabolism. In this respect, amorphous...
Urinary Excretion of Silicon in Men, Non-pregnant Women, and Pregnant Women
Catarina Magnusson, Ravin Jugdaohsingh, Lena Hulthen, Anna Westerlund, Jonathan J. Powell, Maria Ransjö
Jun 28, 2020
Abstract: Silicon is a trace element found mainly in plant-based food and proposed to be beneficial for bone health. Urinary excretion of Si has been shown to be a surrogate measure of its uptake in the gastrointestinal tract....
Urinary Excretion of Silicon in Men, Non-pregnant Women, and Pregnant Women
Catarina Magnusson, Ravin Jugdaohsingh, Lena Hulthen, Anna Westerlund, Jonathan J Powell, Maria Ransjö
Mar 26, 2020
Silicon is a trace element found mainly in plant-based food and proposed to be beneficial for bone health. Urinary excretion of Si has been shown to be a surrogate measure of its uptake in the gastrointestinal tract. The...
Urinary Excretion of Silicon in Men, Non-pregnant Women, and Pregnant Women
Catarina Magnusson, Ravin Jugdaohsingh, Lena Hulthen, Anna Westerlund, Jonathan J. Powell, Maria Ransjö
Jun 06, 2020
Abstract: Silicon is a trace element found mainly in plant-based food and proposed to be beneficial for bone health. Urinary excretion of Si has been shown to be a surrogate measure of its uptake in the gastrointestinal tract....
The silicon supplement 'Monomethylsilanetriol' is safe and increases the body pool of silicon in healthy Pre-menopausal women.
BACKGROUND: Monomethylsilanetriol (MMST) has been used for decades as an oral silicon supplement for bone and connective tissue health, although there are no formal data on its in vivo utilisation or safety following sustained...
Soluble silica stimulates osteogenic differentiation and gap junction communication in human dental follicle cells
Pamela Uribe, Anders Johansson, Ravin Jugdaohsingh, Jonathan J. Powell, Catarina Magnusson, Marcela Davila, Anna Westerlund, Maria Ransjö
Jun 18, 2020
Abstract: Several studies have indicated that dietary silicon (Si) is beneficial for bone homeostasis and skeletal health. Furthermore, Si-containing bioactive glass biomaterials have positive effects on bone regeneration when...
Heavy metal contamination in pristine environments
Constanza Toro-Valdivieso, Ravin Jugdaohsingh, Jonathan J. Powell, Joseph I. Hoffman, Jaume Forcada, Charles Moore, Barbara Blacklaws
Mar 28, 2023
Ecology conservation and global change biology RESEARCH ARTICLES Cadmium Mercury silicon Heavy metals marine mammal pinniped
Published by: The Royal Society
Soluble silica stimulates osteogenic differentiation and gap junction communication in human dental follicle cells.
Pamela Uribe, Anders Johansson, Ravin Jugdaohsingh, Jonathan J Powell, Catarina Magnusson, Marcela Davila, Anna Westerlund, Maria Ransjö
Jun 18, 2021
Several studies have indicated that dietary silicon (Si) is beneficial for bone homeostasis and skeletal health. Furthermore, Si-containing bioactive glass biomaterials have positive effects on bone regeneration when used for...
Choline-stabilized orthosilicic acid supplementation as an adjunct to calcium/vitamin D3 stimulates markers of bone formation in osteopenic females
Bone mineral health is sensitively related to environmental cadmium exposure- experimental and human data.
Aleksandra Buha, Ravin Jugdaohsingh, Vesna Matovic, Zorica Bulat, Biljana Antonijevic, Jemma G Kerns, Allen Goodship, Alister Hart, Jonathan J Powell
Jun 19, 2019
Exposure to cadmium (Cd) is recognised as one of the risk factors for osteoporosis, although critical exposure levels and exact mechanisms are still unknown. Here, we first confirmed that in male Wistar rats challenged orally...
Unexplored nutritive potential of tomato to combat global malnutrition
Sanskriti Vats, Ruchi Bansal, Nitika Rana, Surbhi Kumawat, Vacha Bhatt, Pravin Jadhav, Vijay Kale, Atul Sathe, Humira Sonah, Ravin Jugdaohsingh, Tilak Raj Sharma, Rupesh Deshmukh
Oct 27, 2020
Tomato, a widely consumed vegetable crop, offers a real potential to combat human nutritional deficiencies. Tomatoes are rich in micronutrients and other bioactive compounds (including vitamins, carotenoids, and minerals) that...
Dietary Silicon Deficiency Does Not Exacerbate Diet-Induced Fatty Lesions in Female ApoE Knockout Mice.
Ravin Jugdaohsingh, Katharina Kessler, Barbara Messner, Martin Stoiber, Liliana D Pedro, Heinrich Schima, Günther Laufer, Jonathan J Powell, David Bernhard
May 18, 2018
BACKGROUND: Dietary silicon has been positively linked with vascular health and protection against atherosclerotic plaque formation, but the mechanism of action is unclear. OBJECTIVES: We investigated the effect of dietary...
aorta silicon content aortic lesions apoE knockout mice collagen and elastin contents dietary silicon elastic structure and morphology Monomethylsilanetriol Nutrition serum lipids tensile strength and elasticity Animals Aorta Apolipoproteins E Atherosclerosis Body Weight Cholesterol HDL Cholesterol LDL Diet Diet High-Fat Dietary Supplements Disease Models Animal Endothelium Vascular Female Mice Mice Inbred C57BL Mice Knockout Plaque Atherosclerotic silicon Triglycerides
Formulation of Metal-Organic Framework-Based Drug Carriers by Controlled Coordination of Methoxy PEG Phosphate
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