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The Source of the Current of Injury
Jacques Loeb and Reinhard Beutner. The source of the current of injury
Reprinted from Science, 1912, Jun 21, 35(912):970-971
Published by: Rockefeller University
Two-year outcomes of minimally invasive XEN Gel Stent implantation in primary open-angle and pseudoexfoliation glaucoma.
PURPOSE: The aim of this study was to evaluate the efficacy of XEN® Gel Stent implantation in the treatment of primary open-angle glaucoma (POAG) and pseudoexfoliation glaucoma (XFG) regarding the reduction of intraocular...
Ab interno XEN Gel Stent Glaucoma minimally invasive glaucoma surgery Exfoliation syndrome Female Follow-Up Studies glaucoma drainage implants Glaucoma Open-Angle Humans Intraocular Pressure Male Minimally Invasive Surgical Procedures Prosthesis Design Retrospective Studies Stents Time Factors Tonometry Ocular Treatment Outcome
Comparison of frequency and time domain methods of assessment of cerebral autoregulation in traumatic brain injury.
Xiuyun Liu, Marek Czosnyka, Joseph Donnelly, Karol P Budohoski, Georgios V Varsos, Nathalie Nasr, Ken M Brady, Matthias Reinhard, Peter J Hutchinson, Peter Smielewski
Dec 03, 2014
Shallow water equations with depth-dependent anisotropic porosity for subgrid-scale topography
This paper derives a novel formulation of the depth-averaged shallow water equations with anisotropic porosity for computational efficiency reasons. The aim is to run simulations on coarser grids while maintaining an acceptable...
Lane Detection Algorithm Based on Road Structure and Extended Kalman Filter
Lane detection still demonstrates low accuracy and missing robustness when recorded markings are interrupted by strong light or shadows or missing marking. This article proposes a new algorithm using a model of road structure...
Published by: IGI Global Scientific Publishing
"I am not delusional!" Sensory dysaesthesia secondary to degenerative cervical myelopathy.
Degenerative cervical myelopathy (DCM) is the most common cause of adult spinal cord dysfunction, most classically presenting with a broad-based gait and clumsy hands. Limb sensory loss and paraesthesia are considered common...
Recombination Rate Heterogeneity within Arabidopsis Disease Resistance Genes.
Kyuha Choi, Carsten Reinhard, Heïdi Serra, Piotr A Ziolkowski, Charles J Underwood, Xiaohui Zhao, Thomas J Hardcastle, Nataliya E Yelina, Catherine Griffin, Matthew Jackson, Christine Mézard, Gil McVean, Gregory P Copenhaver, Ian R Henderson
Jul 29, 2016
Molecular and atomic gas along and across the main sequence of star-forming galaxies
Amelie Saintonge, Barbara Catinella, Luca Cortese, Reinhard Genzel, Riccardo Giovanelli, Martha P. Haynes, Steven Janowiecki, Carsten Kramer, Katharina A. Lutz, David Schiminovich, Linda J. Tacconi, Stijn Wuyts, Gioacchino Accurso
Oct 21, 2016
We use spectra from the ALFALFA, GASS and COLD GASS surveys to quantify variations in the mean atomic and molecular gas mass fractions throughout the SFR-M* plane and along the main sequence (MS) of star-forming...
Distinction of early complement classical and lectin pathway activation via quantification of C1s/C1-INH and MASP-1/C1-INH complexes using novel ELISAs.
Lisa Hurler, Erik JM Toonen, Erika Kajdácsi, Bregje van Bree, Ricardo JMGE Brandwijk, Wieke de Bruin, Paul A Lyons, Laura Bergamaschi, Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) COVID BioResource Collaboration, György Sinkovits, László Cervenak, Reinhard Würzner, Zoltán Prohászka
Dec 24, 2022
The most commonly used markers to assess complement activation are split products that are produced through activation of all three pathways and are located downstream of C3. In contrast, C4d derives from the cleavage of C4 and...
C1-INH complexes C1s/C1-INH complex MASP-1/C1-INH complex assay development and validation classical pathway activation early complement activation lectin pathway activation Adult Humans Complement C1 Inhibitor Protein Complement System Proteins covid-19 Lectins Mannose-Binding Protein-Associated Serine Proteases Enzyme-Linked Immunosorbent Assay
Gene drives for schistosomiasis transmission control
Theresa Maier, Nicolas James Wheeler, Erica K. O. Namigai, Josh Tycko, Richard Ernest Grewelle, Yimtubezinash Woldeamanuel, Katharina Klohe, Javier Perez-Saez, Susanne H. Sokolow, Giulio A. De Leo, Timothy P. Yoshino, Mostafa Zamanian, Jutta Reinhard-Rupp
Dec 19, 2019
Schistosomiasis is one of the most important and widespread neglected tropical diseases (NTD), with over 200 million people infected in more than 70 countries; the disease has nearly 800 million people at risk in endemic areas....
RNA-Seq Time Series of Vitis vinifera Bud Development Reveals Correlation of Expression Patterns with the Local Temperature Profile.
Boas Pucker, Anna Schwandner, Sarah Becker, Ludger Hausmann, Prisca Viehöver, Reinhard Töpfer, Bernd Weisshaar, Daniela Holtgräwe
Nov 13, 2020
Plants display sophisticated mechanisms to tolerate challenging environmental conditions and need to manage their ontogenesis in parallel. Here, we set out to generate an RNA-Seq time series dataset throughout grapevine (Vitis...
NRASQ61K melanoma tumor formation is reduced by p38-MAPK14 activation in zebrafish models and NRAS-mutated human melanoma cells.
Ishani Banik, Phil F Cheng, Christopher M Dooley, Jana Travnickova, Munise Merteroglu, Reinhard Dummer, Elizabeth E Patton, Elisabeth M Busch-Nentwich, Mitchell P Levesque
Sep 18, 2020
NRAS mutation Zebrafish Anisomycin Melanoma p38-MAPK14 pathway Animals Anisomycin Apoptosis Cell Proliferation GTP Phosphohydrolases Gene Expression Regulation Neoplastic Humans Melanoma Membrane Proteins Mitogen-Activated Protein Kinase 14 Mutation Protein Kinase Inhibitors Protein Synthesis Inhibitors Tumor Cells Cultured Zebrafish
Distinction of early complement classical and lectin pathway activation via quantification of C1s/C1-INH and MASP-1/C1-INH complexes using novel ELISAs.
Lisa Hurler, Erik JM Toonen, Erika Kajdácsi, Bregje van Bree, Ricardo JMGE Brandwijk, Wieke de Bruin, Paul A Lyons, Laura Bergamaschi, Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) COVID BioResource Collaboration, György Sinkovits, László Cervenak, Reinhard Würzner, Zoltán Prohászka
Nov 21, 2022
Gene drives for schistosomiasis transmission control.
Theresa Maier, Nicolas James Wheeler, Erica KO Namigai, Josh Tycko, Richard Ernest Grewelle, Yimtubezinash Woldeamanuel, Katharina Klohe, Javier Perez-Saez, Susanne H Sokolow, Giulio A De Leo, Timothy P Yoshino, Mostafa Zamanian, Jutta Reinhard-Rupp
Jan 27, 2020
Schistosomiasis is one of the most important and widespread neglected tropical diseases (NTD), with over 200 million people infected in more than 70 countries; the disease has nearly 800 million people at risk in endemic areas....
Galactic Winds across the Gas-rich Merger Sequence. I. Highly Ionized N v and O vi Outflows in the QUEST Quasars*
Abstract
This program is part of QUEST (Quasar/ULIRG Evolutionary Study) and seeks to examine the gaseous environments of z ≲ 0.3 quasars and ULIRGs as a...
Sylvain Veilleux, David SN Rupke, Weizhe Liu, Anthony To, Margaret Trippe, Todd M Tripp, Fred Hamann, Reinhard Genzel, Dieter Lutz, Roberto Maiolino, Hagai Netzer, Kenneth R Sembach, Eckhard Sturm, Linda Tacconi, Stacy H Teng
Feb 11, 2022
Differential Inhibition of Human Atherosclerotic Plaque-Induced Platelet Activation by Dimeric GPVI-Fc and Anti-GPVI Antibodies
Janina Jamasbi, Remco TA Megens, Mariaelvy Bianchini, Götz Münch, Martin Ungerer, Alexander Faussner, Shachar Sherman, Adam Walker, Pankaj Goyal, Stephanie Jung, Richard Brandl, Christian Weber, Reinhard Lorenz, Richard Farndale, Natalie Elia, Wolfgang Siess
Jun 01, 2015
Integrin-Mediated Focal Anchorage Drives Epithelial Zippering during Mouse Neural Tube Closure.
Matteo A Molè, Gabriel L Galea, Ana Rolo, Antonia Weberling, Oleksandr Nychyk, Sandra C De Castro, Dawn Savery, Reinhard Fässler, Patricia Ybot-González, Nicholas DE Greene, Andrew J Copp
Feb 28, 2020
Epithelial fusion is a key process of morphogenesis by which tissue connectivity is established between adjacent epithelial sheets. A striking and poorly understood feature of this process is "zippering," whereby a fusion point...
Cell Adhesion epithelial zippering Extracellular Matrix Fibronectin Fusion gap closure Integrins Morphogenesis Neurulation spina bifida Actomyosin Animals Cell Fusion Embryo Mammalian Epithelial Cells Female focal adhesions Integrin beta1 Mice Mice Inbred BALB C Mice Inbred C57BL Mice Knockout Morphogenesis Neural Crest Neural Tube Neurulation
Real-time deformability cytometry reveals sequential contraction and expansion during neutrophil priming.
Kathleen R Bashant, Arlette Vassallo, Christoph Herold, Reinhard Berner, Leonhard Menschner, Julien Subburayalu, Mariana J Kaplan, Charlotte Summers, Jochen Guck, Edwin R Chilvers, Nicole Toepfner
Mar 11, 2019
It has become increasingly apparent that the biomechanical properties of neutrophils impact on their trafficking through the circulation and in particularly through the pulmonary capillary bed. The retention of polarized or...
Automated insulin delivery
Jennifer L Sherr, Lutz Heinemann, G Alexander Fleming, Richard M Bergenstal, Daniela Bruttomesso, Hélène Hanaire, Reinhard W Holl, John R Petrie, Anne L Peters, Mark Evans
Nov 05, 2022
A technological solution for the management of diabetes in people who require intensive insulin therapy has been sought for decades. The last 10 years have seen substantial growth in devices that can be integrated into clinical...
Longitudinal RNA-Seq Analysis of Vertebrate Aging Identifies Mitochondrial Complex I as a Small-Molecule-Sensitive Modifier of Lifespan.
Mario Baumgart, Steffen Priebe, Marco Groth, Nils Hartmann, Uwe Menzel, Luca Pandolfini, Philipp Koch, Marius Felder, Michael Ristow, Christoph Englert, Reinhard Guthke, Matthias Platzer, Alessandro Cellerino
Mar 01, 2016
GAGE Nothobranchius furzeri RNA transport RNA-seq aging history trait hormesis hourglass life ribosome lifespan regulation longevity longitudinal study mitohormesis rejuvenation weighted gene coexpression network analysis (WGCNA) Zebrafish Animals Cyprinodontiformes Longitudinal Studies RNA Sequence Analysis RNA Vertebrates
Molecular and atomic gas along and across the main sequence of star-forming galaxies
Amelie Saintonge, Barbara Catinella, Luca Cortese, Reinhard Genzel, Riccardo Giovanelli, Martha P. Haynes, Steven Janowiecki, Carsten Kramer, Katharina A. Lutz, David Schiminovich, Linda J. Tacconi, Stijn Wuyts, Gioacchino Accurso
Oct 21, 2016
We use spectra from the ALFALFA, GASS and COLD GASS surveys to quantify variations in the mean atomic and molecular gas mass fractions throughout the SFR-M* plane and along the main sequence (MS) of star-forming...
Cross-calibration of CO- versus dust-based gas masses and assessment of the <i>dynamical </i>mass budget in <i>Herschel</i>-SDSS Stripe82 galaxies
Caroline Bertemes, Stijn Wuyts, Dieter Lutz, Natascha M Förster schreiber, Reinhard Genzel, Robert F Minchin, Carole G Mundell, David Rosario, Amélie Saintonge, Linda Tacconi
Aug 01, 2018
We present a cross-calibration of CO- and dust-based molecular gas masses at z ≤ 0.2. Our results are based on a survey with the IRAM 30-m telescope collecting CO(1–0) measurements of 78 massive (logM⋆/M⊙> 10) galaxies with...
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