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Establishing the plane of symmetry for lumen formation and bilateral brain formation in the zebrafish neural rod.
The lumen of the zebrafish neural tube develops precisely at the midline of the solid neural rod primordium. This process depends on cell polarisation and cell rearrangements, both of which are manifest at the midline of the...
Macromolecular interactions in the nucleoporin p62 complex of rat nuclear pores
Nuclear pore complexes are constructed from a large number of different proteins, called collectively nucleoporins. One of these nucleoporins, p62, has an alpha-helical coiled-coil COOH-terminal rod domain linked to an...
Surface-induced nonlinearity enhancement in subwavelength rod waveguides
We develop a perturbative theory to describe optical propagation in subwavelength rod waveguides. In this approach, we account for loss and nonlinearity in the boundary conditions. A comparison to the traditional perturbative...
CanRisk Tool-A Web Interface for the Prediction of Breast and Ovarian Cancer Risk and the Likelihood of Carrying Genetic Pathogenic Variants.
Tim Carver, Simon Hartley, Andrew Lee, Alex P Cunningham, Stephanie Archer, Chantal Babb de Villiers, Jonathan Roberts, Rod Ruston, Fiona M Walter, Marc Tischkowitz, Douglas F Easton, Antonis C Antoniou
Dec 16, 2020
BACKGROUND: The CanRisk Tool (https://canrisk.org) is the next-generation web interface for the latest version of the BOADICEA (Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm) state-of-the-art...
Surface-induced nonlinearity enhancement in subwavelength rod waveguides
We develop a perturbative theory to describe optical propagation in subwavelength rod waveguides. In this approach, we account for loss and nonlinearity in the boundary conditions. A comparison to the traditional perturbative...
Mirror-symmetric microtubule assembly and cell interactions drive lumen formation in the zebrafish neural rod.
Clare E Buckley, Xiaoyun Ren, Laura C Ward, Gemma C Girdler, Claudio Araya, Mary J Green, Brian S Clark, Brian A Link, Jonathan DW Clarke
Feb 01, 2019
By analysing the cellular and subcellular events that occur in the centre of the developing zebrafish neural rod, we have uncovered a novel mechanism of cell polarisation during lumen formation. Cells from each side of the...
Animals Body Patterning Carrier Proteins Cell Communication Cell Division Cell Movement Cell Polarity Embryo Nonmammalian Green Fluorescent Proteins Luminescent Agents Microtubules Mutation Neural Tube Neurulation Nocodazole Protein Transport Recombinant Fusion Proteins Tubulin Modulators Zebrafish Zebrafish Proteins rab GTP-Binding Proteins
Post-Doctoral Researcher's Conceptions of Research
This paper uses the analysis of metaphors to study the conceptions of research held by a sample of post-doctoral researchers at five Australian universities. It is based on an analysis of the metaphors the researchers use in...
Published by: University of Cambridge
Newly Identified Effects of Injector Nozzle Fouling in Diesel Engines
This paper describes newly identified effects of fouled injectors in diesel engines. As well as restricting and disrupting fuel flow into the combustion chamber, injector fouling has wider impacts on the engine, and these...
Diesel engine Injector fouling NOx emissions thermal efficiency /dk/atira/pure/subjectarea/asjc/1500/1500 name=General Chemical Engineering /dk/atira/pure/subjectarea/asjc/2100/2103 name=Fuel Technology /dk/atira/pure/subjectarea/asjc/2100/2102 name=Energy Engineering and Power Technology /dk/atira/pure/subjectarea/asjc/1600/1605 name=Organic Chemistry
The Self in Research and Other Matters
Rod Pitcher
Apr 13, 2010
This study uses metaphor analysis to examine doctoral students’ conceptions obtained from their responses to an on-line survey. The conceptions examined were the conception of self in research, the conception of the PhD, the...
Published by: University of Cambridge
Kinematic Behaviour of a Novel Pedicle Screw-Rod Fixation System for the Canine Lumbosacral Joint
Objective: To determine the biomechanical behaviour of a novel distraction-stabilization system, consisting of an intervertebral distraction bolt, polyaxial screws and connecting rods, in the canine lumbosacral spine.
Study...
Effects of off-plane deformation and biased bi-axial pre-strains on a planar contractile dielectric elastomer actuator
Dielectric elastomers are in a special class of electro-active polymers known for generating expansion in plane and contraction in thickness under voltage application. This paper advancesthe understanding of a planar contractile...
Far-Red and Near-IR AIE-Active Fluorescent Organic Nanoprobes with Enhanced Tumor-Targeting Efficacy
Andong Shao, Yongshu Xie, Shaojia Zhu, Zhiqian Guo, Shiqin Zhu, Jin Guo, Ping Shi, Tony D. James, He Tian, Wei Hong Zhu
Jun 15, 2015
The rational design of high-performance fluorescent materials for cancer targeting in vivo is still challenging. A unique molecular design strategy is presented that involves tailoring aggregation-induced emission...
Newly Identified Effects of Injector Nozzle Fouling in Diesel Engines
This paper describes newly identified effects of fouled injectors in diesel engines. As well as restricting and disrupting fuel flow into the combustion chamber, injector fouling has wider impacts on the engine, and these...
Diesel engine Injector fouling NOx emissions thermal efficiency /dk/atira/pure/subjectarea/asjc/1500/1500 name=General Chemical Engineering /dk/atira/pure/subjectarea/asjc/2100/2103 name=Fuel Technology /dk/atira/pure/subjectarea/asjc/2100/2102 name=Energy Engineering and Power Technology /dk/atira/pure/subjectarea/asjc/1600/1605 name=Organic Chemistry
Handwriting with sound-speed imaging using ultrasound computed tomography.
This letter proposes the use of ultrasound computed tomography (USCT) for handwriting by imaging sound velocity changes in a medium caused by a rod. The rod was used as a writing object, and the tomographic instrument was able...
Far-Red and Near-IR AIE-Active Fluorescent Organic Nanoprobes with Enhanced Tumor-Targeting Efficacy
Andong Shao, Yongshu Xie, Shaojia Zhu, Zhiqian Guo, Shiqin Zhu, Jin Guo, Ping Shi, Tony D. James, He Tian, Wei Hong Zhu
Jun 15, 2015
The rational design of high-performance fluorescent materials for cancer targeting in vivo is still challenging. A unique molecular design strategy is presented that involves tailoring aggregation-induced emission...
Effects of off-plane deformation and biased bi-axial pre-strains on a planar contractile dielectric elastomer actuator
Dielectric elastomers are in a special class of electro-active polymers known for generating expansion in plane and contraction in thickness under voltage application. This paper advancesthe understanding of a planar contractile...
Handwriting with sound-speed imaging using ultrasound computed tomography.
This letter proposes the use of ultrasound computed tomography (USCT) for handwriting by imaging sound velocity changes in a medium caused by a rod. The rod was used as a writing object, and the tomographic instrument was able...
Retinal regions shape human and murine Müller cell proteome profile and functionality.
Lew Kaplan, Corinne Drexler, Anna M Pfaller, Santra Brenna, Kirsten A Wunderlich, Andrea Dimitracopoulos, Juliane Merl-Pham, Maria-Theresa Perez, Ursula Schlötzer-Schrehardt, Volker Enzmann, Marijana Samardzija, Berta Puig, Peter Fuchs, Kristian Franze, Stefanie M Hauck, Antje Grosche
Nov 05, 2022
The human macula is a highly specialized retinal region with pit-like morphology and rich in cones. How Müller cells, the principal glial cell type in the retina, are adapted to this environment is still poorly understood. We...
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