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Foundations for Knowledge and Belief Management
Roderic Girle
Jul 01, 2021
Three foundational principles are introduced: intelligent systems such as those that would pass the Turing test should display multi-agent or interactional intelligence; multi-agent systems should be based on conceptual...
Published by: IGI Global Scientific Publishing
Developing a Relative Humidity Correction for Low-Cost Sensors Measuring Ambient Particulate Matter.
There is increasing concern about the health impacts of ambient Particulate Matter (PM) exposure. Traditional monitoring networks, because of their sparseness, cannot provide sufficient spatial-temporal measurements...
Linking e-health records, patient-reported symptoms and environmental exposure data to characterise and model COPD exacerbations
Elizabeth Moore, Lia Chatzidiakou, Roderic L Jones, Liam Smeeth, Sean Beevers, Frank J Kelly, Jennifer K Quint, Benjamin Barratt
Jul 29, 2016
COPD Exacerbation Monitor pollution Adult Aged Aged 80 and over Air Pollutants Air Pollution Cohort Studies Data Collection Electronic Health Records Environmental Exposure Environmental Monitoring Female Humans London Male Middle Aged Models Biological Pulmonary Disease Chronic Obstructive Research Design Self Report Severity of Illness Index
The Use of Chest Voice in African-American Religious Singing
Robert T. Townsend
Nov 19, 2013
Chest resonance is used during singing events in most African-American churches. Actually, it is the way of singing for most folk singing. I remember the presentation by a Russian professor demonstrating the folk singing of his...
Published by: Faculty of Education
The Use of Chest Voice in African-American Religious Singing
Robert T. Townsend
Nov 19, 2013
Chest resonance is used during singing events in most African-American churches. Actually, it is the way of singing for most folk singing. I remember the presentation by a Russian professor demonstrating the folk singing of his...
Published by: Faculty of Education
Recruitment of patients with Chronic Obstructive Pulmonary Disease (COPD) from the Clinical Practice Research Datalink (CPRD) for research.
Jennifer K Quint, Elisabeth Moore, Adam Lewis, Maimoona Hashmi, Kirin Sultana, Mark Wright, Liam Smeeth, Lia Chatzidiakou, Roderic Jones, Sean Beevers, Sefki Kolozali, Frank Kelly, Benjamin Barratt
Sep 20, 2018
Databases of electronic health records (EHR) are not only a valuable source of data for health research but have also recently been used as a medium through which potential study participants can be screened, located and...
Measuring Aerosol Phase Changes and Hygroscopicity with a Microresonator Mass Sensor.
Arthur T Zielinski, Peter J Gallimore, Paul T Griffiths, Roderic L Jones, Ashwin A Seshia, Markus Kalberer
Oct 22, 2018
The interaction between atmospheric aerosol particles and water vapor influences aerosol size, phase, and composition, parameters which critically influence their impacts in the atmosphere. Methods to accurately measure aerosol...
Automated classification of time-activity-location patterns for improved estimation of personal exposure to air pollution.
Lia Chatzidiakou, Anika Krause, Mike Kellaway, Yiqun Han, Yilin Li, Elizabeth Martin, Frank J Kelly, Tong Zhu, Benjamin Barratt, Roderic L Jones
Jan 08, 2023
BACKGROUND: Air pollution epidemiology has primarily relied on measurements from fixed outdoor air quality monitoring stations to derive population-scale exposure. Characterisation of individual time-activity-location patterns...
Constraining emission estimates of carbon monoxide using a perturbed emissions ensemble with observations
Le Yuan, Olalekan A.M. Popoola, Christina Hood, David Carruthers, Roderic L. Jones, Huan Liu, Zhaofeng Lv, Qiang Zhang, Alexander T. Archibald
Sep 22, 2021
article Air quality model Emissions inventory Emissions uncertainty Ensemble simulations Low-cost sensors Network measurements
Published by: Springer Netherlands
A Systematic Review Protocol of Opportunities for Noncommunicable Disease Prevention via Public Space Initiatives in African Cities.
Ebele RI Mogo, Taibat Lawanson, Louise Foley, Clarisse Mapa-Tassou, Felix Assah, Toluwalope Ogunro, Victor Onifade, Damilola Odekunle, Richard Unuigboje, Nfondoh Blanche, Rose Alani, Lia Chatzidiakou, Olalekan Popoola, Roderic Jones, Tolu Oni
Mar 28, 2022
Public spaces have the potential to produce equitable improvements in population health. This mixed-methods systematic review aims to understand the components of, determinants, risks, and outcomes associated with public space...
Automated classification of time-activity-location patterns for improved estimation of personal exposure to air pollution.
Lia Chatzidiakou, Anika Krause, Mike Kellaway, Yiqun Han, Yilin Li, Elizabeth Martin, Frank J Kelly, Tong Zhu, Benjamin Barratt, Roderic L Jones
Dec 09, 2022
BACKGROUND: Air pollution epidemiology has primarily relied on measurements from fixed outdoor air quality monitoring stations to derive population-scale exposure. Characterisation of individual time-activity-location patterns...
Analysis of the variability of airborne particulate matter with prevailing meteorological conditions across a semi-urban environment using a network of low-cost air quality sensors.
Opeyemi R Omokungbe, Olusegun G Fawole, Oyediran K Owoade, Olalekan AM Popoola, Roderic L Jones, Felix S Olise, Muritala A Ayoola, Pelumi O Abiodun, Adekunle B Toyeje, Ayodele P Olufemi, Lukman A Sunmonu, Olawale E Abiye
Sep 09, 2020
The concentrations of fine and coarse fractions of airborne particulate matter (PM) and meteorological variables (wind speed, wind direction, temperature and relative humidity) were measured at six selected locations in Ile Ife...
Using low-cost sensor technologies and advanced computational methods to improve dose estimations in health panel studies
Lia Chatzidiakou, Anika Krause, Yiqun Han, Wu Chen, Li Yan, Olalekan AM Popoola, Mike Kellaway, Yangfeng Wu, Jing Liu, Min Hu, AIRLESS team, Ben Barratt, Frank J Kelly, Tong Zhu, Roderic L Jones
Jul 01, 2020
Identifying Patterns and Sources of Fine and Ultrafine Particulate Matter in London Using Mobile Measurements of Lung-Deposited Surface Area.
Rishabh U Shah, Lauren E Padilla, Daniel R Peters, Megan Dupuy-Todd, Elizabeth R Fonseca, Geoffrey Q Ma, Olalekan AM Popoola, Roderic L Jones, Jim Mills, Nicholas A Martin, Ramón A Alvarez
Jan 24, 2023
Immune Cell Associations with Cancer Risk.
Luis Palomero, Ivan Galván-Femenía, Rafael de Cid, Roderic Espín, Daniel R Barnes, CIMBA, Eline Blommaert, Miguel Gil-Gil, Catalina Falo, Agostina Stradella, Dan Ouchi, Albert Roso-Llorach, Concepció Violan, María Peña-Chilet, Joaquín Dopazo, Ana Isabel Extremera, Mar García-Valero, Carmen Herranz, Francesca Mateo, Elisabetta Mereu, Jonathan Beesley, Georgia Chenevix-Trench, Cecilia Roux, Tak Mak, Joan Brunet, Razq Hakem, Chiara Gorrini, Antonis C Antoniou, Conxi Lázaro, Miquel Angel Pujana
Aug 19, 2020
Proper immune system function hinders cancer development, but little is known about whether genetic variants linked to cancer risk alter immune cells. Here, we report 57 cancer risk loci associated with differences in immune...
Molecular signatures of plastic phenotypes in two eusocial insect species with simple societies.
Solenn Patalano, Anna Vlasova, Chris Wyatt, Philip Ewels, Francisco Camara, Pedro G Ferreira, Claire L Asher, Tomasz P Jurkowski, Anne Segonds-Pichon, Martin Bachman, Irene González-Navarrete, André E Minoche, Felix Krueger, Ernesto Lowy, Marina Marcet-Houben, Jose Luis Rodriguez-Ales, Fabio S Nascimento, Shankar Balasubramanian, Toni Gabaldon, James E Tarver, Simon Andrews, Heinz Himmelbauer, William OH Hughes, Roderic Guigó, Wolf Reik, Seirian Sumner
Dec 04, 2015
DNA Methylation genome sequencing phenotypic plasticity Social evolution transcriptomes Animals Ants Base Sequence Brain DNA Methylation Gene Expression Regulation Genome Insect HIERARCHY Social High-Throughput Nucleotide Sequencing MicroRNAs Models Genetic Molecular Sequence Data Phenotype Social Behavior Transcriptome Wasps
Transcriptional diversity during lineage commitment of human blood progenitors.
Lu Chen, Myrto Kostadima, Joost HA Martens, Giovanni Canu, Sara P Garcia, Ernest Turro, Kate Downes, Iain C Macaulay, Ewa Bielczyk-Maczynska, Sophia Coe, Samantha Farrow, Pawan Poudel, Frances Burden, Sjoert BG Jansen, William J Astle, Antony Attwood, Tadbir Bariana, Bernard de Bono, Alessandra Breschi, John C Chambers, Bridge Consortium, Fizzah A Choudry, Laura Clarke, Paul Coupland, Martijn van der Ent, Wendy N Erber, Joop H Jansen, Rémi Favier, Matthew E Fenech, Nicola Foad, Kathleen Freson, Chris van Geet, Keith Gomez, Roderic Guigo, Daniel Hampshire, Anne M Kelly, Hindrik HD Kerstens, Jaspal S Kooner, Michael Laffan, Claire Lentaigne, Charlotte Labalette, Tiphaine Martin, Stuart Meacham, Andrew Mumford, Sylvia Nürnberg, Emilio Palumbo, Bert A van der Reijden, David Richardson, Stephen J Sammut, Greg Slodkowicz, Asif U Tamuri, Louella Vasquez, Katrin Voss, Stephen Watt, Sarah Westbury, Paul Flicek, Remco Loos, Nick Goldman, Paul Bertone, Randy J Read, Sylvia Richardson, Ana Cvejic, Nicole Soranzo, Willem H Ouwehand, Hendrik G Stunnenberg, Mattia Frontini, Augusto Rendon
Nov 12, 2014
Re-annotation of 191 developmental and epileptic encephalopathy-associated genes unmasks de novo variants in SCN1A.
Charles A Steward, Jolien Roovers, Marie-Marthe Suner, Jose M Gonzalez, Barbara Uszczynska-Ratajczak, Dmitri Pervouchine, Stephen Fitzgerald, Margarida Viola, Hannah Stamberger, Fadi F Hamdan, Berten Ceulemans, Patricia Leroy, Caroline Nava, Anne Lepine, Electra Tapanari, Don Keiller, Stephen Abbs, Alba Sanchis-Juan, Detelina Grozeva, Anthony S Rogers, Mark Diekhans, Roderic Guigó, Robert Petryszak, Berge A Minassian, Gianpiero Cavalleri, Dimitrios Vitsios, Slavé Petrovski, Jennifer Harrow, Paul Flicek, F Lucy Raymond, Nicholas J Lench, Peter De Jonghe, Jonathan M Mudge, Sarah Weckhuysen, Sanjay M Sisodiya, Adam Frankish
Jan 09, 2020
The developmental and epileptic encephalopathies (DEE) are a group of rare, severe neurodevelopmental disorders, where even the most thorough sequencing studies leave 60-65% of patients without a molecular diagnosis. Here, we...
Re-annotation of 191 developmental and epileptic encephalopathy-associated genes unmasks de novo variants in SCN1A
Charles A. Steward, Jolien Roovers, Marie-Marthe Suner, Jose M. Gonzalez, Barbara Uszczynska-Ratajczak, Dmitri Pervouchine, Stephen Fitzgerald, Margarida Viola, Hannah Stamberger, Fadi F. Hamdan, Berten Ceulemans, Patricia Leroy, Caroline Nava, Anne Lepine, Electra Tapanari, Don Keiller, Stephen Abbs, Alba Sanchis-Juan, Detelina Grozeva, Anthony S. Rogers, Mark Diekhans, Roderic Guigó, Robert Petryszak, Berge A. Minassian, Gianpiero Cavalleri, Dimitrios Vitsios, Slavé Petrovski, Jennifer Harrow, Paul Flicek, F. Lucy Raymond, Nicholas J. Lench, Peter De Jonghe, Jonathan M. Mudge, Sarah Weckhuysen, Sanjay M. Sisodiya, Adam Frankish
Nov 03, 2020
Re-annotation of 191 developmental and epileptic encephalopathy-associated genes unmasks de novo variants in SCN1A.
Charles A Steward, Jolien Roovers, Marie-Marthe Suner, Jose M Gonzalez, Barbara Uszczynska-Ratajczak, Dmitri Pervouchine, Stephen Fitzgerald, Margarida Viola, Hannah Stamberger, Fadi F Hamdan, Berten Ceulemans, Patricia Leroy, Caroline Nava, Anne Lepine, Electra Tapanari, Don Keiller, Stephen Abbs, Alba Sanchis-Juan, Detelina Grozeva, Anthony S Rogers, Mark Diekhans, Roderic Guigó, Robert Petryszak, Berge A Minassian, Gianpiero Cavalleri, Dimitrios Vitsios, Slavé Petrovski, Jennifer Harrow, Paul Flicek, F Lucy Raymond, Nicholas J Lench, Peter De Jonghe, Jonathan M Mudge, Sarah Weckhuysen, Sanjay M Sisodiya, Adam Frankish
Jan 27, 2020
The developmental and epileptic encephalopathies (DEE) are a group of rare, severe neurodevelopmental disorders, where even the most thorough sequencing studies leave 60-65% of patients without a molecular diagnosis. Here, we...
Re-annotation of 191 developmental and epileptic encephalopathy-associated genes unmasks de novo variants in SCN1A
Charles A. Steward, Jolien Roovers, Marie-Marthe Suner, Jose M. Gonzalez, Barbara Uszczynska-Ratajczak, Dmitri Pervouchine, Stephen Fitzgerald, Margarida Viola, Hannah Stamberger, Fadi F. Hamdan, Berten Ceulemans, Patricia Leroy, Caroline Nava, Anne Lepine, Electra Tapanari, Don Keiller, Stephen Abbs, Alba Sanchis-Juan, Detelina Grozeva, Anthony S. Rogers, Mark Diekhans, Roderic Guigó, Robert Petryszak, Berge A. Minassian, Gianpiero Cavalleri, Dimitrios Vitsios, Slavé Petrovski, Jennifer Harrow, Paul Flicek, F. Lucy Raymond, Nicholas J. Lench, Peter De Jonghe, Jonathan M. Mudge, Sarah Weckhuysen, Sanjay M. Sisodiya, Adam Frankish
Dec 01, 2020
Altered regulation of BRCA1 exon 11 splicing is associated with breast cancer risk in carriers of BRCA1 pathogenic variants.
Gorka Ruiz de Garibay, Ignacio Fernandez-Garcia, Sylvie Mazoyer, Flavia Leme de Calais, Pietro Ameri, Sangeeta Haydeliz Martinez-Ruiz, Francesca Damiola, Laure Barjhoux, Mads Thomassen, Lars VB Andersen, Carmen Herranz, Francesca Mateo, Luis Palomero, Roderic Espin, Antonio Gómez, Nadia García, Daniel Jimenez, Núria Bonifaci, Ana I Extremera, Julio Castaño, Angel Raya, Eduardo Eyras, Xose S Puente, Joan Brunet, Conxi Lázaro, Gemo, CIMBA, Paolo Radice, Daniel R Barnes, Antonis C Antoniou, Amanda B Spurdle, Miguel de la Hoya, Diana Baralle, Mary Helen Barcellos-Hoff, Miquel A Pujana
Sep 01, 2021
Germline pathogenic variants in BRCA1 confer a high risk of developing breast and ovarian cancer. The BRCA1 exon 11 (formally exon 10) is one of the largest exons and codes for the nuclear localization signals of the...
Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells
L Chen, B Ge, FP Casale, L Vasquez, T Kwan, D Garrido-Martín, S Watt, Y Yan, K Kundu, S Ecker, A Datta, D Richardson, F Burden, D Mead, AL Mann, JM Fernandez, S Rowlston, SP Wilder, S Farrow, X Shao, JJ Lambourne, A Redensek, CA Albers, V Amstislavskiy, S Ashford, K Berentsen, L Bomba, G Bourque, D Bujold, S Busche, M Caron, S-H Chen, W Cheung, O Delaneau, ET Dermitzakis, H Elding, I Colgiu, FO Bagger, P Flicek, E Habibi, V Iotchkova, E Janssen-Megens, B Kim, H Lehrach, E Lowy, A Mandoli, F Matarese, MT Maurano, JA Morris, V Pancaldi, F Pourfarzad, K Rehnstrom, A Rendon, T Risch, N Sharifi, M-M Simon, M Sultan, A Valencia, K Walter, S-Y Wang, M Frontini, SE Antonarakis, L Clarke, M-L Yaspo, S Beck, R Guigo, D Rico, JHA Martens, WH Ouwehand, TW Kuijpers, DS Paul, HG Stunnenberg, O Stegle, K Downes, T Pastinen, N Soranzo
Dec 22, 2016
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease
WJ Astle, H Elding, T Jiang, D Allen, D Ruklisa, AL Mann, D Mead, H Bouman, F Riveros-Mckay, MA Kostadima, JJ Lambourne, S Sivapalaratnam, K Downes, K Kundu, L Bomba, K Berentsen, JR Bradley, LC Daugherty, O Delaneau, SF Garner, L Grassi, M Haimel, EM Janssen-Megens, A Kaan, M Kamat, B Kim, A Mandoli, J Marchini, K Freson, J Guerrero, J Marchini, JHA Martens, S Meacham, K Megy, J O'Connell, R Petersen, N Sharifi, SM Sheard, JR Staley, S Tuna, M van der Ent, K Walter, S-Y Wang, E Wheeler, SP Wilder, V Iotchkova, C Moore, J Sambrook, HG Stunnenberg, E Di Angelantonio, S Kaptoge, TW Kuijpers, E Carrillo-de-Santa-Pau, D Juan, D Rico, A Valencia, L Chen, B Ge, L Vasquez, T Kwan, D Garrido-Martín, S Watt, Y Yang, R Guigo, S Beck, DS Paul, T Pastinen, D Bujold, G Bourque, M Frontini, J Danesh, DJ Roberts, WH Ouwehand, AS Butterworth, N Soranzo
Jan 16, 2017
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