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Field evaluation of a novel, rapid diagnostic assay, and molecular epidemiology of enterotoxigenic E. coli among Zambian children presenting with diarrhea.
Suwilanji Silwamba, Obvious N Chilyabanyama, Fraser Liswaniso, Caroline C Chisenga, Roma Chilengi, Gordon Dougan, Geoffrey Kwenda, Subhra Chakraborty, Michelo Simuyandi
Sep 04, 2022
BACKGROUND: Enterotoxigenic Escherichia coli (ETEC) is one of the top aetiologic agents of diarrhea in children under the age of 5 in low-middle income countries (LMICs). The lack of point of care diagnostic tools for routine...
Field evaluation of a novel, rapid diagnostic assay, and molecular epidemiology of enterotoxigenic E. coli among Zambian children presenting with diarrhea.
Suwilanji Silwamba, Obvious N Chilyabanyama, Fraser Liswaniso, Caroline C Chisenga, Roma Chilengi, Gordon Dougan, Geoffrey Kwenda, Subhra Chakraborty, Michelo Simuyandi
Aug 17, 2022
BACKGROUND: Enterotoxigenic Escherichia coli (ETEC) is one of the top aetiologic agents of diarrhea in children under the age of 5 in low-middle income countries (LMICs). The lack of point of care diagnostic tools for routine...
Body structural and cellular aging of women with low socioeconomic status in Hungary
Dorina Annar, Piroska Feher, Anna Madarasi, Nicholas Mascie-Taylor, Anna Kekesi, Irina Kalabiska, Agota Muzsnai, Annamaria Zsakai
Aug 11, 2021
OBJECTIVES: The health status of an individual is determined not only by their genetic background but also by their physical environment, social environment and access and use of the health care system. The Roma are one of the...
The Performance of HE4 Alone and in Combination with CA125 for the Detection of Ovarian Cancer in an Enriched Primary Care Population
Human epididymis 4 (HE4) is a promising ovarian cancer biomarker, but it has not been evaluated in primary care. In this prospective observational study, we investigated the diagnostic accuracy of HE4 alone and in...
Chloe E Barr, Garth Funston, David Jeevan, Sudha Sundar, Luke Ta Mounce, Emma J Crosbie
Apr 25, 2022
Introduction
Funder: Università degli Studi Roma Tre
Structural and functional brain networks of individual differences in trait anger and anger control
The ability to experience, use and eventually control anger is crucial to maintain well-being and build healthy relationships. Despite its relevance, the neural mechanisms behind individual differences in experiencing and...
Structural Features Related to Affective Instability Correctly Classify Patients With Borderline Personality Disorder. A Supervised Machine Learning Approach.
Alessandro Grecucci, Gaia Lapomarda, Irene Messina, Bianca Monachesi, Sara Sorella, Roma Siugzdaite
Mar 14, 2022
Previous morphometric studies of Borderline Personality Disorder (BPD) reported inconsistent alterations in cortical and subcortical areas. However, these studies have investigated the brain at the voxel level using mass...
Transdiagnostic Brain Mapping in Developmental Disorders.
Childhood learning difficulties and developmental disorders are common, but progress toward understanding their underlying brain mechanisms has been slow. Structural neuroimaging, cognitive, and learning data were collected from...
Women with early maltreatment experience show increased resting-state functional connectivity in the theory of mind (ToM) network.
Sara Boccadoro, Roma Siugzdaite, Anna R Hudson, Lien Maeyens, Charlotte Van Hamme, Sven C Mueller
Jan 11, 2021
Background: Experience of childhood maltreatment significantly increases the risk for the development of psychopathology and is associated with impairments in socio-cognitive skills including theory-of-mind (ToM). In turn...
Two Pathways to Self-Harm in Adolescence.
OBJECTIVE: The behavioral and emotional profiles underlying adolescent self-harm, and its developmental risk factors, are relatively unknown. We aimed to identify subgroups of young people who self-harm (YPSH) and longitudinal...
Longitudinal increases in childhood depression symptoms during the COVID-19 lockdown.
Giacomo Bignardi, Edwin S Dalmaijer, Alexander L Anwyl-Irvine, Tess A Smith, Roma Siugzdaite, Stepheni Uh, Duncan E Astle
Nov 23, 2020
OBJECTIVE: There has been widespread concern that so-called lockdown measures, including social distancing and school closures, could negatively impact children's mental health. However, there has been little direct evidence of...
Opportunities and Limitations of Mobile Neuroimaging Technologies in Educational Neuroscience.
The mitochondrial oxidoreductase CHCHD4 is present in a semi-oxidized state in vivo.
Alican J Erdogan, Muna Ali, Markus Habich, Silja L Salscheider, Laura Schu, Carmelina Petrungaro, Luke W Thomas, Margaret Ashcroft, Lars I Leichert, Leticia Prates Roma, Jan Riemer
Jun 19, 2018
Disulfide formation in the mitochondrial intermembrane space is an essential process catalyzed by a disulfide relay machinery. In mammalian cells, the key enzyme in this machinery is the oxidoreductase CHCHD4/Mia40. Here, we...
CHCHD4/ALR/disulfide/redox/mitochondria Animals Disulfides Mice Mitochondria Mitochondrial Membrane Transport Proteins Mitochondrial Precursor Protein Import Complex Proteins Mitochondrial Proteins Organ Specificity Oxidation-Reduction Oxidoreductases Oxidoreductases Acting on Sulfur Group Donors Protein Transport
Tuberculosis in badgers where the bovine tuberculosis epidemic is expanding in cattle in England.
Benjamin Michael Connor Swift, Elsa Sandoval Barron, Rob Christley, Davide Corbetta, Llorenç Grau-Roma, Chris Jewell, Colman O'Cathail, Andy Mitchell, Jess Phoenix, Alison Prosser, Catherine Rees, Marion Sorley, Ranieri Verin, Malcolm Bennett
Oct 25, 2021
Bovine tuberculosis (bTB) is an important animal health and economic problem for the cattle industry and a potential zoonotic threat. Wild badgers (Meles meles) play a role on its epidemiology in some areas of high prevalence in...
The Origin of Inequality. Origini 3, edited by Andrea Cardarelli, Alberto Cazzella and Marcella Frangipane
The article reviews The Origins of Inequality, a collection of essays brought together by Andrea Cardarelli, Alberto Cazzella and Marcella Frangipane following a series of seminars on this theme at the University of Roma La...
Tuberculosis in badgers where the bovine tuberculosis epidemic is expanding in cattle in England.
Benjamin Michael Connor Swift, Elsa Sandoval Barron, Rob Christley, Davide Corbetta, Llorenç Grau-Roma, Chris Jewell, Colman O'Cathail, Andy Mitchell, Jess Phoenix, Alison Prosser, Catherine Rees, Marion Sorley, Ranieri Verin, Malcolm Bennett
Jan 06, 2022
Bovine tuberculosis (bTB) is an important animal health and economic problem for the cattle industry and a potential zoonotic threat. Wild badgers (Meles meles) play a role on its epidemiology in some areas of high prevalence in...
Falerii Novi (Comune Di Fabrica Di Roma, Provincia Di Viterbo, Regione Lazio)
The project is run in collaboration with the British School at Rome and the Soprintendenza Archeologia del Lazio e dell’Etruria Meridionale. It has benefitted from the generous support of the Arts and Humanities Research Council...
ATP synthase deficiency due to TMEM70 mutation leads to ultrastructural mitochondrial degeneration and is amenable to treatment.
Anne K Braczynski, Stefan Vlaho, Klaus Müller, Ilka Wittig, Anna-Eva Blank, Dominique S Tews, Ulrich Drott, Stephanie Kleinle, Angela Abicht, Rita Horvath, Karl H Plate, Werner Stenzel, Hans H Goebel, Andreas Schulze, Patrick N Harter, Matthias Kieslich, Michel Mittelbronn
Mar 07, 2019
TMEM70 is involved in the biogenesis of mitochondrial ATP synthase and mutations in the TMEM70 gene impair oxidative phosphorylation. Herein, we report on pathology and treatment of ATP synthase deficiency in four siblings. A...
The KRAB Zinc Finger Protein Roma/Zfp157 Is a Critical Regulator of Cell-Cycle Progression and Genomic Stability.
A generative network model of neurodevelopmental diversity in structural brain organization
Danyal Akarca, Petra E. Vértes, Edward T. Bullmore, Duncan E. Astle, Kate Baker, Susan E. Gathercole, Joni Holmes, Rogier A. Kievit, Tom Manly, Joe Bathelt, Marc Bennett, Giacomo Bignardi, Sarah Bishop, Erica Bottacin, Lara Bridge, Diandra Brkic, Annie Bryant, Sally Butterfield, Elizabeth M. Byrne, Gemma Crickmore, Edwin S. Dalmaijer, Fánchea Daly, Tina Emery, Laura Forde, Grace Franckel, Delia Fuhrmann, Andrew Gadie, Sara Gharooni, Jacalyn Guy, Erin Hawkins, Agnieszka Jaroslawska, Sara Joeghan, Amy Johnson, Jonathan Jones, Silvana Mareva, Elise Ng-Cordell, Sinead O’Brien, Cliodhna O’Leary, Joseph P. Rennie, Ivan Simpson-Kent, Roma Siugzdaite, Tess A. Smith, Stephani Uh, Maria Vedechkina, Francesca Woolgar, Natalia Zdorovtsova, Mengya Zhang
Jul 28, 2021
Psycho-social factors associated with mental resilience in the Corona lockdown
Ilya M. Veer, Antje Riepenhausen, Matthias Zerban, Carolin Wackerhagen, Lara M. C. Puhlmann, Haakon Engen, Göran Köber, Sophie A. Bögemann, Jeroen Weermeijer, Aleksandra Uściłko, Netali Mor, Marta A. Marciniak, Adrian Dahl Askelund, Abbas Al-Kamel, Sarah Ayash, Giulia Barsuola, Vaida Bartkute-Norkuniene, Simone Battaglia, Yaryna Bobko, Sven Bölte, Paolo Cardone, Edita Chvojková, Kaja Damnjanović, Joana De Calheiros Velozo, Lena de Thurah, Yacila I. Deza-Araujo, Annika Dimitrov, Kinga Farkas, Clémence Feller, Mary Gazea, Donya Gilan, Vedrana Gnjidić, Michal Hajduk, Anu P. Hiekkaranta, Live S. Hofgaard, Laura Ilen, Zuzana Kasanova, Mohsen Khanpour, Bobo Hi Po Lau, Dionne B. Lenferink, Thomas B. Lindhardt, Dávid Á. Magas, Julian Mituniewicz, Laura Moreno-López, Sofiia Muzychka, Maria Ntafouli, Aet O’Leary, Ilenia Paparella, Nele Põldver, Aki Rintala, Natalia Robak, Anna M. Rosická, Espen Røysamb, Siavash Sadeghi, Maude Schneider, Roma Siugzdaite, Mirta Stantić, Ana Teixeira, Ana Todorovic, Wendy W. N. Wan, Rolf van Dick, Klaus Lieb, Birgit Kleim, Erno J. Hermans, Dorota Kobylińska, Talma Hendler, Harald Binder, Inez Myin-Germeys, Judith M. C. van Leeuwen, Oliver Tüscher, Kenneth S. L. Yuen, Henrik Walter, Raffael Kalisch
Jan 21, 2021
Psycho-social factors associated with mental resilience in the Corona lockdown.
Ilya M Veer, Antje Riepenhausen, Matthias Zerban, Carolin Wackerhagen, Lara MC Puhlmann, Haakon Engen, Göran Köber, Sophie A Bögemann, Jeroen Weermeijer, Aleksandra Uściłko, Netali Mor, Marta A Marciniak, Adrian Dahl Askelund, Abbas Al-Kamel, Sarah Ayash, Giulia Barsuola, Vaida Bartkute-Norkuniene, Simone Battaglia, Yaryna Bobko, Sven Bölte, Paolo Cardone, Edita Chvojková, Kaja Damnjanović, Joana De Calheiros Velozo, Lena de Thurah, Yacila I Deza-Araujo, Annika Dimitrov, Kinga Farkas, Clémence Feller, Mary Gazea, Donya Gilan, Vedrana Gnjidić, Michal Hajduk, Anu P Hiekkaranta, Live S Hofgaard, Laura Ilen, Zuzana Kasanova, Mohsen Khanpour, Bobo Hi Po Lau, Dionne B Lenferink, Thomas B Lindhardt, Dávid Á Magas, Julian Mituniewicz, Laura Moreno-López, Sofiia Muzychka, Maria Ntafouli, Aet O'Leary, Ilenia Paparella, Nele Põldver, Aki Rintala, Natalia Robak, Anna M Rosická, Espen Røysamb, Siavash Sadeghi, Maude Schneider, Roma Siugzdaite, Mirta Stantić, Ana Teixeira, Ana Todorovic, Wendy WN Wan, Rolf van Dick, Klaus Lieb, Birgit Kleim, Erno J Hermans, Dorota Kobylińska, Talma Hendler, Harald Binder, Inez Myin-Germeys, Judith MC van Leeuwen, Oliver Tüscher, Kenneth SL Yuen, Henrik Walter, Raffael Kalisch
Feb 05, 2021
The SARS-CoV-2 pandemic is not only a threat to physical health but is also having severe impacts on mental health. Although increases in stress-related symptomatology and other adverse psycho-social outcomes, as well as their...
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