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The Treatment of Cartilage Damage Using Human Mesenchymal Stem Cell-Derived Extracellular Vesicles
Damage to joints through injury or disease can result in cartilage loss, which if left untreated can lead to inflammation and ultimately osteoarthritis. There is currently no cure for osteoarthritis and management focusses on...
Zinc Complexes for PLA Formation and Chemical Recycling:
A series of Zn II complexes, based on propylenediamine Schiff bases, have been prepared and fully characterized. X-ray crystallography and NMR spectroscopy identified significant differences in the solid and...
Di-Zinc Aryl Complexes
Charles Romain, Jennifer A. Garden, Gemma Trott, Antoine Buchard, Andrew J. P. White, Charlotte Katherine Williams
May 29, 2017
Two new di-zinc aryl complexes, [LZn2Ph2] and [LZn2(C6F5)2], coordinated by a diphenol tetraamine macrocyclic ligand are prepared and fully characterized, including by single crystal X-ray diffraction experiments. The complexes'...
Zinc Complexes for PLA Formation and Chemical Recycling:
A series of Zn II complexes, based on propylenediamine Schiff bases, have been prepared and fully characterized. X-ray crystallography and NMR spectroscopy identified significant differences in the solid and...
Synovium-Derived Mesenchymal Stem Cell Transplantation in Cartilage Regeneration
Articular cartilage damaged through trauma or disease has a limited ability to repair. Untreated, focal lesions progress to generalized changes including osteoarthritis. Musculoskeletal disorders including osteoarthritis are the...
Shaken and stirred
The viscosity of suspensions of large (≥10 μm) particles diverges at high solid fractions due to proliferation of frictional particle contacts. Reducing friction, to allow or improve flowability, is usually achieved by tuning...
Acute Neurologic Complications of COVID-19 and Postacute Sequelae of COVID-19.
Neurologic complications can be seen in mild to severe COVID-19 with a higher risk in patients with severe COVID-19. These can occur as a direct consequence of viral infection or consequences of treatments. The spectrum ranges...
Mechanism of nuclear movements in a multinucleated cell.
Multinucleated cells are important in many organisms, but the mechanisms governing the movements of nuclei sharing a common cytoplasm are not understood. In the hyphae of the plant pathogenic fungus Ashbya gossypii, nuclei move...
A method for the fast and photon-efficient analysis of time-domain fluorescence lifetime image data over large dynamic ranges.
Fluorescence lifetime imaging (FLIM) allows the quantification of sub-cellular processes in situ, in living cells. A number of approaches have been developed to extract the lifetime from time-domain FLIM data, but they are often...
Di-Zinc Aryl Complexes
Charles Romain, Jennifer A. Garden, Gemma Trott, Antoine Buchard, Andrew J. P. White, Charlotte Katherine Williams
May 29, 2017
Two new di-zinc aryl complexes, [LZn2Ph2] and [LZn2(C6F5)2], coordinated by a diphenol tetraamine macrocyclic ligand are prepared and fully characterized, including by single crystal X-ray diffraction experiments. The complexes'...
The unquantified mass loss of Northern Hemisphere marine-terminating glaciers from 2000-2020.
Stick or Spill? Scaling Relationships for the Binding Energies of Adsorbates on Single-Atom Alloy Catalysts.
Single-atom alloy catalysts combine catalytically active metal atoms, present as dopants, with the selectivity of coinage metal hosts. Determining whether adsorbates stick at the dopant or spill over onto the host is key to...
Published by: The journal of physical chemistry letters
Micro-scale finishing of the surface and form of a Ti-6Al-4V lightweight rotor obtained by laser powder bed fusion used for air bearing
Claude Sanz, Romain Gerard, Paul Morantz, Ahmed Chérif, Paul Shore, Hélène Mainaud-Durand, Alexander J.G. Lunt
Oct 01, 2018
The European Organisation for Nuclear Research, CERN, is in the process of designing and testing parts for the next generation of linear accelerators. In order to operate the experiments, the pre-alignment precision of the...
The unquantified mass loss of Northern Hemisphere marine-terminating glaciers from 2000-2020.
William Kochtitzky, Luke Copland, Wesley Van Wychen, Romain Hugonnet, Regine Hock, Julian A Dowdeswell, Toby Benham, Tazio Strozzi, Andrey Glazovsky, Ivan Lavrentiev, David R Rounce, Romain Millan, Alison Cook, Abigail Dalton, Hester Jiskoot, Jade Cooley, Jacek Jania, Francisco Navarro
Nov 15, 2022
In the Northern Hemisphere, ~1500 glaciers, accounting for 28% of glacierized area outside the Greenland Ice Sheet, terminate in the ocean. Glacier mass loss at their ice-ocean interface, known as frontal ablation, has not yet...
Structural analysis of herpes simplex virus by optical super-resolution imaging.
Romain F Laine, Anna Albecka, Sebastian van de Linde, Eric J Rees, Colin M Crump, Clemens F Kaminski
Jan 30, 2015
Animals Antibodies Monoclonal Cell Line Cryoelectron Microscopy Female Herpesvirus 1 Human Humans Image Processing Computer-Assisted Keratinocytes Mice Mice Inbred BALB C Microscopy Microscopy Fluorescence Optical Imaging Recombinant Proteins Simplexvirus Viral Envelope Proteins Viral Proteins Viral Structural Proteins Virion
Evaluation of a Pseudotyped Virus Neutralisation Test for the Measurement of Equine Influenza Virus-Neutralising Antibody Responses Induced by Vaccination and Infection.
Rebecca Kinsley, Stéphane Pronost, Manuelle De Bock, Nigel Temperton, Janet M Daly, Romain Paillot, Simon Scott
Aug 24, 2020
Equine influenza is a major respiratory disease of horses that is largely controlled by vaccination in some equine populations. Virus-neutralising antibodies, the mainstay of the protective immune response, are problematic in...
SpeS
C Coral Dominguez-Medina, Nicola L Rash, Sylvain Robillard, Carl Robinson, Androulla Efstratiou, Karen Broughton, Julian Parkhill, Matthew TG Holden, Maria R Lopez-Alvarez, Romain Paillot, Andrew S Waller
Aug 03, 2020
Bacterial superantigens (sAgs) are powerful activators of the immune response that trigger unspecific T cell responses accompanied by the release of proinflammatory cytokines. Streptococcus equi (S. equi) and Streptococcus...
Streptococcus equi Streptococcus zooepidemicus Adjuvant horse immune response strangles superantigen vaccine Adjuvants Immunologic Antigen Presentation Bacterial Proteins Exotoxins Histocompatibility Antigens Class II Humans Membrane Proteins Meningitis Phylogeny Receptors Antigen T-Cell Streptococcal Infections Streptococcus equi Superantigens vaccines
Impulsive prepotent actions and tics in Tourette disorder underpinned by a common neural network.
Cyril Atkinson-Clement, Camille-Albane Porte, Astrid de Liege, Yanica Klein, Cecile Delorme, Benoit Beranger, Romain Valabregue, Cecile Gallea, Trevor W Robbins, Andreas Hartmann, Yulia Worbe
Oct 11, 2021
Tourette disorder (TD), which is characterized by motor and vocal tics, is not in general considered as a product of impulsivity, despite a frequent association with attention deficit hyperactivity disorder and impulse control...
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