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Results: 72
Three-dimensional morphological analysis of placental terminal villi.
Romina Plitman Mayo, Yassen Abbas, D Stephen Charnock-Jones, Graham J Burton, Gil Marom
Oct 01, 2019
Transport of nutrients and waste between the maternal and fetal circulations during pregnancy takes place at the final branches of the placental villous trees. Therefore, and unsurprisingly, pregnancy complications have been...
The relationship between human placental morphometry and ultrasonic measurements of utero-placental blood flow and fetal growth.
An Inquiry Into the Use of Generative AI and Its Implications in Education
The emergence of generative AI technologies has provoked considerable debate among educators regarding their role in education. This study is an investigation of the benefits, disadvantages, and potential strategies for...
Published by: IGI Global Scientific Publishing
Structure Prediction of Li--Sn and Li--Sb Intermetallics for Lithium-ion Batteries Anodes.
A variety of new stable and metastable Li–Sn and Li–Sb intermetallics are presented using the ab initio random structure searching (AIRSS) and species swapping methods. There include LiSn2–P4/mmm, Li2Sn3–P-1, Li7Sn9–P42/n...
Genetic variation in stromal proteins decorin and lumican with breast cancer
Linda E Kelemen, Fergus J Couch, Shahana Ahmed, Alison M Dunning, Paul DP Pharoah, Douglas F Easton, Zachary S Fredericksen, Robert A Vierkant, V Shane Pankratz, Ellen L Goode, Christopher G Scott, David N Rider, Xianshu Wang, James R Cerhan, Celine M Vachon
Jun 14, 2011
INTRODUCTION: The stroma is the supportive framework of biologic tissue in the breast, consisting of various proteins such as the proteoglycans, decorin and lumican. Altered expression of decorin and lumican is associated with...
A Phase II study of neoadjuvant axitinib for reducing the extent of venous tumour thrombus in clear cell renal cell cancer with venous invasion (NAXIVA).
Grant D Stewart, Sarah J Welsh, Stephan Ursprung, Ferdia A Gallagher, James O Jones, Jacqui Shields, Christopher G Smith, Thomas J Mitchell, Anne Y Warren, Axel Bex, Ekaterini Boleti, Jade Carruthers, Tim Eisen, Kate Fife, Abdel Hamid, Alexander Laird, Steve Leung, Jahangeer Malik, Iosif A Mendichovszky, Faiz Mumtaz, Grenville Oades, Andrew N Priest, Antony CP Riddick, Balaji Venugopal, Michelle Welsh, Kathleen Riddle, Lisa EM Hopcroft, NAXIVA Trial Group, Robert J Jones
Sep 14, 2022
BACKGROUND: Surgery for renal cell carcinoma (RCC) with venous tumour thrombus (VTT) extension into the renal vein (RV) and/or inferior vena cava (IVC) has high peri-surgical morbidity/mortality. NAXIVA assessed the response of...
Dendritic Cells Charged with Apoptotic Tumor Cells Induce Long-Lived Protective CD4+ and CD8+ T Cell Immunity against B16 Melanoma
Dendritic cells (DCs) are potent APCs and attractive vectors for cancer immunotherapy. Using the B16 melanoma, a poorly immunogenic experimental tumor that expresses low levels of MHC class I products, we investigated whether...
Apoptosis bone marrow cell antigen recognition cytokine release lymph node lymphatic drainage melanoma cell tumor immunity
Published by: Rockefeller University
Mayo's impact on patent applications related to biotechnology, diagnostics and personalized medicine.
On the sixth anniversary of Mayo v. Prometheus, what impact has the US Supreme Court decision had on patent subject-matter eligibility and the prosecution of biotech-related patent applications before the US Patent and Trademark...
Odorant transport in a hagfish
Todor G. Cross, Olivia C. Mayo, Graham Martin, Matthew P. Cross, David K. Ludlow, Katharine Fraser, Jonathan Cox
Nov 01, 2024
Odorant transport is of fundamental and applied importance. Using computational simulations, we studied odorant transport in an anatomically accurate model of the nasal passage of a hagfish (probably Eptatretus stoutii). We...
Hagfish lamprey Microfluidic devices Navigation Stereo olfaction /dk/atira/pure/subjectarea/asjc/1300/1303 name=Biochemistry /dk/atira/pure/subjectarea/asjc/1300/1314 name=Physiology /dk/atira/pure/subjectarea/asjc/1100/1104 name=Aquatic Science /dk/atira/pure/subjectarea/asjc/1100/1103 name=Animal Science and Zoology /dk/atira/pure/subjectarea/asjc/1300/1312 name=Molecular Biology
Astrocytes actively support long-range molecular clock synchronization of segregated neuronal populations.
Lidia Giantomasi, João F Ribeiro, Olga Barca-Mayo, Mario Malerba, Ermanno Miele, Davide De Pietri Tonelli, Luca Berdondini
Mar 24, 2023
Odorant transport in a hagfish
Todor G. Cross, Olivia C. Mayo, Graham Martin, Matthew P. Cross, David K. Ludlow, Katharine Fraser, Jonathan Cox
Nov 01, 2024
Odorant transport is of fundamental and applied importance. Using computational simulations, we studied odorant transport in an anatomically accurate model of the nasal passage of a hagfish (probably Eptatretus stoutii). We...
Hagfish lamprey Microfluidic devices Navigation Stereo olfaction /dk/atira/pure/subjectarea/asjc/1300/1303 name=Biochemistry /dk/atira/pure/subjectarea/asjc/1300/1314 name=Physiology /dk/atira/pure/subjectarea/asjc/1100/1104 name=Aquatic Science /dk/atira/pure/subjectarea/asjc/1100/1103 name=Animal Science and Zoology /dk/atira/pure/subjectarea/asjc/1300/1312 name=Molecular Biology
A Ramsey characterisation of eventually periodic words
A factorisation $x = u_1 u_2 \cdots$ of an infinite word $x$ on alphabet $X$
is called `monochromatic', for a given colouring of the finite words $X^*$ on
alphabet $X$, if each $u_i$ is the same colour. Wojcik and Zamboni proved...
ROS-Scavenging Enzymes as an Antioxidant Response to High Concentration of Anthracene in the Liverwort Marchantia polymorpha L
Nahuel Spinedi, Romina Storb, Elisabet Aranda, Facundo Romani, Maya Svriz, Santiago A. Varela, Javier E. Moreno, Sebastian Fracchia, Juan Cabrera, Ramón Alberto Batista-García, Inés Ponce de León, J. Martín Scervino
Jul 28, 2021
Marchantia polymorpha L. responds to environmental changes using a myriad set of physiological responses, some unique to the lineage related to the lack of a vascular- and root-system. This study investigates the physiological...
CONSORT-SPI 2018 Explanation and Elaboration
Sean Grant, Evan Mayo-Wilson, Paul Montgomery, Geraldine Macdonald, Susan Michie, Sally Hopewell, David Moher, on behalf of the CONSORT-SPI Group
Jan 08, 2019
BACKGROUND: The CONSORT (Consolidated Standards of Reporting Trials) Statement was developed to help biomedical researchers report randomised controlled trials (RCTs) transparently. We have developed an extension to the CONSORT...
CONSORT randomised controlled trial Reporting guideline reporting standards Transparency Behavior Therapy Checklist Consensus Data Accuracy Delphi Technique Endpoint Determination Humans Outcome Assessment Health Care Randomized Controlled Trials as Topic Research Design Social Environment Treatment Outcome
Choroid Plexus Acts as Gatekeeper for TREM2, Abnormal Accumulation of ApoE, and Fibrillary Tau in Alzheimer's Disease and in Down Syndrome Dementia.
Ruma Raha-Chowdhury, James W Henderson, Animesh Alexander Raha, Romina Vuono, Anastasia Bickerton, Elizabeth Jones, Robert Fincham, Kieren Allinson, Anthony Holland, Shahid H Zaman
May 28, 2019
Capacity-Building for Sustainability
An American K-12 cooperative educational services provider (“The Agency”) has an issue: partner school districts are saving money by building internal capacity for professional development, rather than fully utilizing expertise...
Published by: IGI Global Scientific Publishing
Identification of prognostic phenotypes of esophageal adenocarcinoma in two independent cohorts.
Tarek Sawas, Sarah Killcoyne, Prasad G Iyer, Kenneth K Wang, Thomas C Smyrk, John B Kisiel, Yi Qin, David A Ahlquist, Anil K Rustgi, OCCAMS consortium, Rui J Costa, Moritz Gerstung, Rebecca C Fitzgerald, David A Katzka
Nov 23, 2018
BACKGROUND & AIMS: Most patients with esophageal adenocarcinoma (EAC) present de novo. Although this may be due to inadequate screening strategies, the precise reason for this observation is not clear.. We compared survival of...
CD97 stabilises the immunological synapse between dendritic cells and T cells and is targeted for degradation by the Salmonella effector SteD
Ondrej Cerny, Camilla Godlee, Romina Tocci, Nancy E. Cross, Haoran Shi, James C. Williamson, Eric Alix, Paul J. Lehner, David W. Holden
Aug 11, 2021
The Salmonella enterica effector SteD depletes mature MHC class II (mMHCII) molecules from the surface of infected antigen-presenting cells through ubiquitination of the cytoplasmic tail of the mMHCII β chain. This requires the...
Association Between Toll-Like Receptor 4 (TLR4) and Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Genetic Variants and Clinical Progression of Huntington's Disease.
Romina Vuono, Antonina Kouli, Emilie M Legault, Lauriane Chagnon, Kieren S Allinson, Alberto La Spada, REGISTRY Investigators of the European Huntington's Disease Network, Ida Biunno, Roger A Barker, Janelle Drouin-Ouellet
Sep 11, 2019
Polymers of Z α1-antitrypsin are secreted in cell models of disease.
Annamaria Fra, Francesca Cosmi, Adriana Ordoñez, Romina Berardelli, Juan Perez, Noemi A Guadagno, Luciano Corda, Stefan J Marciniak, David A Lomas, Elena Miranda
Feb 12, 2019
Neuroprotective Effect of TREM-2 in Aging and Alzheimer's Disease Model.
Animesh Alexander Raha, James W Henderson, Simon RW Stott, Romina Vuono, Simona Foscarin, Robert P Friedland, Shahid H Zaman, Ruma Raha-Chowdhury
Sep 22, 2016
Alzheimer’ disease choroid plexus macrophages immunomodulation innate immunity Myelination Neurogenesis Neuroinflammation neuroplasticity neuroprotective soluble TREM2 aging Alzheimer Disease Amyloid beta-Protein Precursor Animals Brain Cells Cultured Humans Lipopolysaccharides MACROPHAGES Membrane Glycoproteins meninges Mice Inbred C57BL Mice Transgenic Microglia Neurogenesis Neurons Neuroprotection Presenilin-1 RNA Messenger Rats Sprague-Dawley Receptors Immunologic
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