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Results: 782
Chromosome engineering in zygotes with CRISPR/Cas9.
Deletions, duplications, and inversions of large genomic regions covering several genes are an important class of disease causing variants in humans. Modeling these structural variants in mice requires multistep processes in ES...
Response to Ruby et al
Does disruption of prefrontal cortical activity using transcranial magnetic stimulation (TMS) impair visual metacognition? An initial study supporting this idea (Rounis, Maniscalco, Rothwell, Passingham, & Lau, 2010) motivated...
Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice.
George S Vassiliou, Jonathan L Cooper, Roland Rad, Juan Li, Stephen Rice, Anthony Uren, Lena Rad, Peter Ellis, Rob Andrews, Ruby Banerjee, Carolyn Grove, Wei Wang, Pentao Liu, Penny Wright, Mark Arends, Allan Bradley
Oct 22, 2020
Acute myeloid leukemia (AML) is a molecularly diverse malignancy with a poor prognosis whose largest subgroup is characterized by somatic mutations in NPM1, which encodes nucleophosmin. These mutations, termed NPM1c, result in...
Amino Acid Sequence Animals Base Sequence Disease Progression Gene Expression Gene Knock-In Techniques Hematopoietic Stem Cells Homeodomain Proteins Humans Leukemia Experimental Leukemia Myeloid Acute Mice Mice Transgenic Molecular Sequence Data Mutation Myelopoiesis Nuclear Proteins Nucleophosmin Recombinant Proteins Sequence Homology Amino Acid
Kierkegaard in the Anthropocene
What is the role of hope in the climate crisis? What type of hope does this crisis demand? How can we sustain hope, in order to resist falling into fatalistic despair or paralyzing fear, whilst always guarding against...
Ruby Guyatt
Jun 09, 2020
Ursinus College Bulletin Vol. 12, No. 8, May 1896
Elizabeth Ruby Titzel
Jan 01, 0001
A digitized copy of the May 1896 Ursinus College Bulletin.
Ursinus College Collegeville Pennsylvania Bulletin news Reformed Church literary societies Arbor Day LIBRARY baseball cultural history Higher Education History of Christianity History of Religion Liberal Studies Social History United States History
Published by: Ursinus College
PiggyBac mutagenesis and exome sequencing identify genetic driver landscapes and potential therapeutic targets of EGFR -mutant gliomas
Imran Noorani, Jorge de la Rosa, Yoonha Choi, Alexander Strong, Hannes Ponstingl, M. S. Vijayabaskar, Jusung Lee, Eunmin Lee, Angela Richard-Londt, Mathias Friedrich, Federica Furlanetto, Rocio Fuente, Ruby Banerjee, Fengtang Yang, Frances Law, Colin Watts, Roland Rad, George Vassiliou, Jong Kyoung Kim, Thomas Santarius, Sebastian Brandner, Allan Bradley
Jul 30, 2020
PiggyBac mutagenesis and exome sequencing identify genetic driver landscapes and potential therapeutic targets of EGFR-mutant gliomas.
Imran Noorani, Jorge de la Rosa, Yoon Ha Choi, Alexander Strong, Hannes Ponstingl, MS Vijayabaskar, Jusung Lee, Eunmin Lee, Angela Richard-Londt, Mathias Friedrich, Federica Furlanetto, Rocio Fuente, Ruby Banerjee, Fengtang Yang, Frances Law, Colin Watts, Roland Rad, George Vassiliou, Jong Kyoung Kim, Thomas Santarius, Sebastian Brandner, Allan Bradley
Aug 14, 2020
Glioma is the most common intrinsic brain tumor and also occurs in the spinal cord. Activating EGFR mutations are common in IDH1 wild-type gliomas. However, the cooperative partners of EGFR driving gliomagenesis remain poorly...
PiggyBac mutagenesis and exome sequencing identify genetic driver landscapes and potential therapeutic targets of EGFR -mutant gliomas
Imran Noorani, Jorge de la Rosa, Yoon Ha Choi, Alexander Strong, Hannes Ponstingl, M. S. Vijayabaskar, Jusung Lee, Eunmin Lee, Angela Richard-Londt, Mathias Friedrich, Federica Furlanetto, Rocio Fuente, Ruby Banerjee, Fengtang Yang, Frances Law, Colin Watts, Roland Rad, George Vassiliou, Jong Kyoung Kim, Thomas Santarius, Sebastian Brandner, Allan Bradley
Jul 30, 2021
PiggyBac mutagenesis and exome sequencing identify genetic driver landscapes and potential therapeutic targets of EGFR -mutant gliomas
Imran Noorani, Jorge de la Rosa, Yoon Ha Choi, Alexander Strong, Hannes Ponstingl, M. S. Vijayabaskar, Jusung Lee, Eunmin Lee, Angela Richard-Londt, Mathias Friedrich, Federica Furlanetto, Rocio Fuente, Ruby Banerjee, Fengtang Yang, Frances Law, Colin Watts, Roland Rad, George Vassiliou, Jong Kyoung Kim, Thomas Santarius, Sebastian Brandner, Allan Bradley
Aug 06, 2020
Ursinus College Bulletin Vol. 12, No. 7, April 1896
A digitized copy of the April 1896 Ursinus College Bulletin.
Ursinus College Collegeville Pennsylvania Bulletin news Reformed Church literary societies Samuel Vernon Ruby cultural history Higher Education History of Christianity History of Religion Liberal Studies Social History United States History
Published by: Ursinus College
Meta-Analysis of Cyber Intimate Partner Violence Perpetration and Victimization
Cyber intimate partner violence (C-IPV) is a technology-mediated form of violence. It has been examined only in the last 10 years as a form of violence that can cause psychological damage to its victims. How this phenomenon...
Meta-Analysis of Cyber Intimate Partner Violence Perpetration and Victimization
Cyber intimate partner violence (C-IPV) is a technology-mediated form of violence. It has been examined only in the last 10 years as a form of violence that can cause psychological damage to its victims. How this phenomenon...
Ursinus College Bulletin Vol. 11, No. 3, December 1894
A digitized copy of the December 1894 Ursinus College Bulletin.
Ursinus College Collegeville Pennsylvania Bulletin news Reformed Church literary societies LIBRARY Football cultural history Higher Education History of Christianity History of Religion Liberal Studies Social History United States History
Published by: Ursinus College
PiggyBac mutagenesis and exome sequencing identify genetic driver landscapes and potential therapeutic targets of EGFR -mutant gliomas
Imran Noorani, Jorge de la Rosa, Yoon Ha Choi, Alexander Strong, Hannes Ponstingl, M. S. Vijayabaskar, Jusung Lee, Eunmin Lee, Angela Richard-Londt, Mathias Friedrich, Federica Furlanetto, Rocio Fuente, Ruby Banerjee, Fengtang Yang, Frances Law, Colin Watts, Roland Rad, George Vassiliou, Jong Kyoung Kim, Thomas Santarius, Sebastian Brandner, Allan Bradley
Aug 17, 2020
Intimate technologies for affective development
SA Banerjee
Aug 13, 2021
Recently emerged as transformative fundraising tools for development causes, crowdfunding platforms leverage the ‘feelingful ties’ that connect individuals in pursuit of non-governmental organisation (NGO) fundraising. Focussing...
Studies of G-Protein Coupled Receptors Incorporated Into a Novel, Nanoscale, Membrane-Mimetic System
Sourabh Banerjee
Jan 01, 0001
From first principles of phospholipid â" apolipoprotein A-I (apo A-I) interactions, we hypothesized that the amino acid sequence of apo A-I derived from a different species may exhibit improved properties compared to human apo...
apo A-I interactions g protein coupled receptors (GPCRs) nanoscale apolipoprotein bound bilayers (NABBs) GPCR stoichiometry rhodospin Life Sciences
Published by: Rockefeller University
Monitoring a Meat-Free Pledge with Smartphones
Jared Piazza, Rebecca Gregson, Anastasia Kordoni, Tamara Pfeiler, Matthew Ruby, David Ellis, Ensu Sahin, Maren Reith
Jan 01, 2022
Pledges are a popular strategy to encourage meat reduction, though experimental studies of their efficacy are lacking. Three-hundred and twenty-five participants from three different countries (UK, Germany, Australia) were...
Monitoring a Meat-Free Pledge with Smartphones
Jared Piazza, Rebecca Gregson, Anastasia Kordoni, Tamara Pfeiler, Matthew Ruby, David Ellis, Ensu Sahin, Maren Reith
Jan 01, 2022
Pledges are a popular strategy to encourage meat reduction, though experimental studies of their efficacy are lacking. Three-hundred and twenty-five participants from three different countries (UK, Germany, Australia) were...
Backtracking Search Algorithm With Single and Multi-Objective Function for the Solution of Optimal Power Flow Problem
This manuscript investigates the performance of the backtracking search algorithm (BSA) to minimize various objectives for an economical and secure power system. A variety of single and multi - objectives are delineated and...
Published by: IGI Global Scientific Publishing
Influence of correlated antigen presentation on T-cell negative selection in the thymus.
The thymus is the primary organ for the generation of naive T cells, a key component of the immune system. Tolerance of T cells to self is achieved primarily in the thymic medulla, where immature T cells (thymocytes) sample...
Fragility and correlated dynamics in supercooled liquids.
A connection between the super-Arrhenius behavior of dynamical properties and the correlated dynamics for supercooled liquids is examined for a well known glass forming binary Lennard-Jones mixture and its repulsive counterpart...
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