Rapid and Progressive Regional Brain Atrophy in CLN6 Batten Disease Affected Sheep Measured with Longitudinal Magnetic Resonance Imaging.
Stephen J Sawiak,
Sunthara Rajan Perumal,
Skye R Rudiger,
Loren Matthews,
Nadia L Mitchell,
Clive J McLaughlan,
C Simon Bawden,
David N Palmer,
Timothy Kuchel,
A Jennifer Morton
Feb 13, 2020
Variant late-infantile Batten disease is a neuronal ceroid lipofuscinosis caused by mutations in CLN6. It is a recessive genetic lysosomal storage disease characterised by progressive neurodegeneration. It starts insidiously and...